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Topic: Asymmetric septal hypertrophy


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In the News (Mon 28 May 12)

  
  Asymmetric septal hypertrophy - Health Encyclopedia
hypertrophic cardiomyopathy, idiopathic hypertrophic subaortic stenosis, IHSS (idiopathic hypertrophic subaortic stenosis), obstructive asymmetric septal hypertrophy
Asymmetric septal hypertrophy is often suggested by very deep septal Q waves in leads I, aVL, V5, and V6; a QS complex sometimes occurs in V1 and V2, simulating previous septal infarction.
Asymmetric septal hypertrophyAsymmetric septal hypertrophy is an abnormal thickening of the heart muscle inside the lower left chamber (left ventricle) of the heart.
www.steadyhealth.com /encyclopedia/Asymmetric_septal_hypertrophy   (210 words)

  
 Bioline International Official Site (site up-dated regularly)
Asymmetric (Figure 2) and concentric symmetric hypertrophy (Figure 3) was seen in seven cases each (Table 2).
Septal endocardial thickening in the form of a mirror image of the anterior mitral leaflet in the subaortic region of the left ventricular outflow tract was seen in three cases, with corresponding thickening of the anterior mitral leaflet (Figure 4).
Asymmetric hypertrophy was anteroseptal in four cases, anteroseptal and lateral in two and septal in one case.
www.bioline.org.br /request?jp01048   (2610 words)

  
 Hypertrophic Cardiomyopathy: Heart Failure and Cardiomyopathies: Merck Manual Professional
During systole, the septum thickens, and sometimes the anterior leaflet of the mitral valve, already abnormally oriented because of the abnormally shaped ventricle, is sucked toward the septum by a Venturi effect of high velocity blood flow, further obstructing the outflow tract and decreasing cardiac output.
Septal hypertrophy produces a systolic ejection-type murmur that does not radiate to the neck and may be heard at the left sternal edge in the 3rd or 4th intercostal space.
Genetic counseling is appropriate for patients with asymmetric septal hypertrophy, which appears to accelerate during puberty.
www.merck.com /mmpe/print/sec07/ch074/ch074e.html   (1450 words)

  
 Spencer W - Results of Alcohol Septal Ablation for Hypertrophic
By echocardiography, the patient should have asymmetric septal hypertrophy with an inter-ventricular septal thickness of 1.6 cm or greater and have a septal to posterior wall ratio of 1.3 to 1.0 or greater.
Regression of left ventricular hypertrophy in the remainder of the uninfarcted ventricle combined with a significant decrease in the cardiac cytokine, tumor necrosis factor alpha, a decrease in overall myocyte size and a diminution in total myocardial collagen content have been reported on long-term follow-up (18-19).
Efficacy of non-surgical septal reduction therapy in symptomatic patients with obstructive hypertrophic cardiomyopathy and provocable gradients.
www.fac.org.ar /scvc/llave/interven/spencer/spenceri.htm   (1619 words)

  
 The 18-23-week scan - Chapter 4.08
The latter is also known as asymmetric septal hypertrophy or idiopathic hypertrophic subaortic stenosis.
A transient form of dynamic obstruction of the left outflow tract is seen in infants of diabetic mothers, and is probably the consequence of fetal hyperglycemia and hyperinsulinemia.
Asymmetric septal hypertrophy and hypertrophic cardiomyopathy of fetuses of diabetic mothers, resulting in subaortic stenosis, has been occasionally diagnosed by demonstrating an unusual thickness of the ventricular septum.
www.fetalmedicine.com /18-23scanbook/Chapter4/chap04-08.htm   (459 words)

  
 FOCUS: Nonsurgical Septal Reduction
The inward movement of the hypertrophied septum during systole further narrows the LV outflow tract resulting in high LVOT blood velocities that pull the mitral valve leaflet toward the interventricular septum (Venturi effect).
Schematic diagram of hypertrophic obstructive cardiomyopathy illustrating asymmetric septal hypertrophy (ASH), systolic anterior motion of the mitral valve leaflet (SAM) and obstruction of the left ventricular outflow tract.
The ideal target region is the hypertrophied muscle at the point where the SAM of the mitral valve touches the septum.
www.hmc.org.qa /hmc/heartviews/issue9/FOCUS.htm   (3934 words)

  
 Postgraduate Medicine: Hypertrophic cardiomyopathy
The most common form of hypertrophic cardiomyopathy is diffuse hypertrophy of the ventricular septum and anterolateral free wall (70% to 75% of cases) (figure 2: not shown), followed by basal septal hypertrophy (10% to 15%), concentric hypertrophy (<5%), hypertrophy of the lateral wall (1% to 2%), and apical hypertrophy (5).
Because left ventricular hypertrophy usually develops between the ages of 5 and 15 years, a normal echocardiogram in a child does not exclude the presence of hypertrophic cardiomyopathy (9).
A small amount of alcohol is injected into the septal branch of the left anterior descending artery that supplies the culprit hypertrophied portion of the interventricular septum.
www.postgradmed.com /issues/2000/06_00/deluca.htm   (3212 words)

  
 eMedicine - Cardiomyopathy, Hypertrophic : Article by Diwaker Agarwal, MD
The disease includes asymmetric septal hypertrophy, and idiopathic subaortic stenosis (IHSS), but the term HCM is preferred because the majority (75%) of patients do not present with outflow obstruction (Braunwald, 1997), and 30% do not exhibit asymmetric hypertrophy.
On echocardiograms, asymmetrical septal hypertrophy is defined as a ratio of septal thickness to posterior wall thickness of at least 1.3-1.5.
The left septal surface is flat or it bulges into the LV cavity at its middle or lower portion, in contrast to the normal curve toward the right ventricle.
www.emedicine.com /radio/topic129.htm   (8033 words)

  
  Symmetric and Asymmetric Left Ventricular Hypertrophy in Patients with End-Stage Renal Failure on Long-Term ...   (Site not responding. Last check: 2007-11-03)
Asymmetric septal hypertrophy and impairment of LV outflow can occur in these patients and may contribute to adverse outcomes.
Conclusions: Symmetric LV hypertrophy and asymmetric septal hypertrophy are frequent in patients on maintenance hemodialysis.
Predictors for LV hypertrophy were age and body mass index, and, particularly for asymmetric septal hypertrophy, age and hypertension duration.
clinicalcardiology.org /productcart/pc/briefs/9809briefs/21-672.html   (414 words)

  
 The Turkish Journal of Pediatrics   (Site not responding. Last check: 2007-11-03)
DCRV may be associated with other congenital cardiac anomalies, most commonly with ventricular septal defect and pulmonary stenosis, tetralogy of Fallot, aortic stenosis and regurgitation[1-5].
Hypertrophied anomalous muscle at the infundibular region was resected, as were additional hypertrophied septal and parietal muscle bands.
Associated cardiac anomalies are common in DCRV and include ventricular septal defect (VSD) in 56% to 90% of cases, pulmonary stenosis, atrial septal defect, cor triatriatum, and aortic and subaortic stenosis[1,3,7].
tjp.dergisi.org /text.php3?id=43   (916 words)

  
 Clinicopathologic heterogeneity in hypertrophic cardiomyopathy with regard to age, asymmetric septal hypertrophy, and ...
Clinicopathologic heterogeneity in hypertrophic cardiomyopathy with regard to age, asymmetric septal hypertrophy, and concentric hypertrophy beyond the pediatric age group
Ventricular septal myocyte disarray and intramural coronary artery thickening were far more marked among the young with asymmetric septal hypertrophy than the young with concentric hypertrophy and the elderly.
Much higher degrees of ventricular disarray and intramural coronary artery disease were noted in younger patients with asymmetric septal hypertrophy compared to the elderly patients and the younger patients with concentric hypertrophy.
findarticles.com /p/articles/mi_qa3725/is_199805/ai_n8803110?lstpn=article_results&lstpc=search&lstpr=external&lstprs=other&lstwid=1&lstwn=search_results&lstwp=body_middle   (817 words)

  
 [No title]   (Site not responding. Last check: 2007-11-03)
Asymmetric septal hypertrophy (ASH), present in the majority of dogs and humans with HC, is present in only 30% of cats with HC.
Other disorders that produce left ventricular and septal hypertrophy, such as hyperthyroidism, systemic hypertension, and aortic stenosis, must also be ruled out.
In the case of sudden death, the diagnosis is made at necropsy by disclosure of typical gross and histologic cardiac pathology.
www.vetlatranquera.com.ar /pages/wild/small_animal_2.htm   (1727 words)

  
 eMedicine - Cardiomyopathy, Hypertrophic : Article Excerpt by: Michael E Zevitz, MD
This hypertrophy can occur in any region of the left ventricle but frequently involves the interventricular septum, which results in an obstruction of flow through the left ventricular (LV) outflow tract.
The pressure gradient appears to be related to further narrowing of an already small outflow tract (by the marked asymmetric septal hypertrophy and possibly an abnormal location of the mitral valve) by the systolic anterior motion of the mitral valve against the hypertrophied septum.
The molecular basis for HCM is defects in several of the genes encoding for the sarcomeric proteins, such as myosin heavy chain, actin, tropomyosin, and titin.
www.emedicine.com /med/byname/cardiomyopathy-hypertrophic.htm   (575 words)

  
 Left Ventricle Hypertrophy   (Site not responding. Last check: 2007-11-03)
Hypertrophy of the left ventricle is defined as a wall thickness greater than 1.
Prostate, benign hypertrophy, hyperplasiaThis larger-than-normal amount of blood that collects in the left ventricle puts pressure on the walls of the heart, causing the heart muscle to increase in thickness (hypertrophy)Asymmetric septal hypertrophy and concentric left ventricle hypertrophy are known causes of cardiac dysrhythmias and sudden death.
Cardiac MR may be useful to help differentiate theseAsymmetric septal hypertrophy and concentric left ventricle hypertrophy are known causes of cardiac dysrhythmias and sudden death.
ventricle.protofind.com /left-ventricle-hypertrophy.htm   (251 words)

  
 Doppler Echocardiography in Fetuses of Diabetic Mothers [MJM 1996 2: 24-30]
Similarly, the fetal heart, rich in insulin receptors (5), may undergo increased ventricular septal thickening in the presence of high insulin levels in the third trimester, culminating in asymmetric septal hypertrophy (6-8).
Asymmetric septal hypertrophy, found at increased incidence in infants of insulin-dependent diabetic mothers, often hinders diastolic function, as evidenced by decreased cardiac output and increased morbidity, including persistent pulmonary hypertension of the newborn, and perhaps idiopathic respiratory distress syndrome (1,2,8).
Asymmetric septal hypertrophy in infants of diabetic mothers.
www.medicine.mcgill.ca /mjm/v02n01/doppler.html   (3204 words)

  
 Asymmetric septal hypertrophy and propranolol treatment in a case of Ullrich-Noonan syndrome -- Jackson et al. 42 (5): ...
Asymmetric septal hypertrophy and propranolol treatment in a case of Ullrich-Noonan syndrome -- Jackson et al.
Asymmetric septal hypertrophy and propranolol treatment in a case of Ullrich-Noonan syndrome
septal hypertrophy was diagnosed by echocardiography and confirmed at
heart.bmjjournals.com /cgi/content/abstract/42/5/611   (141 words)

  
 HCMA :: Hypertrophic Cardiomyopathy Association | The HCM Heart | The Heart in Hypertrophic Cardiomyopathy
It can be seen from figure 5 that the hypertrophy is usually greatest in the upper septum, in the area where blood flows out of the heart into the aorta or "outflow tract".
In some cases of asymmetric septal hypertrophy obstruction to the outflow of blood from the heart may occur as shown here.
This is known as "symmetric" or "concentric" ventricular hypertrophy.
www.4hcm.org /WCMS/index.php?heart   (612 words)

  
 Congenital Heart Disease - When Chambers and Valves Are in Normal Sequence and Position
Without an atrial septal defect to provide some mixing of blood and a route (such as a patent ductus arteriosus or surgically placed central shunt) to provide some flow to the lungs, survival is impossible.
Symmetric or asymmetric septal hypertrophy may be present and the aortic valve shows abnormal systolic closure and fluttering.
The asymmetric septal hypertrophy is variable in degree and position and may be secondary to other lesions, such as coarctation, systemic hypertension, right ventricular hypertrophy, or valvular aortic stenosis.
www.echoincontext.com /advanced/chd_11.asp   (619 words)

  
 [No title]   (Site not responding. Last check: 2007-11-03)
In the first demonstration of asymmetric hypertrophy of the heart in young adults, Teare (1958) reported the autopsy findings in 9 cases of sudden death in young subjects distributed in 6 families.
In 1 family with the leu908-to-val mutation of the MYH7 gene (160760.0010), central core disease was demonstrated on soleus muscle biopsy, although cardiac hypertrophy was absent on echocardiogram in 2 adults and 3 children.
(2000) found that the magnitude of hypertrophy is directly related to the risk of sudden death and then is a strong and independent predictor of prognosis.
zeta.embl-heidelberg.de:8000 /srs5bin/cgi-bin/wgetz?-e+[omim-id:192600]   (5319 words)

  
 Aortic Stenosis
Associated with inherited disorders, asymmetric septal hypertrophy, hypertrophic obstructive cardiomyopathy.
If the obstruction is not relieved, critical aortic stenosis can lead to secondary endocardial fibroelastosis Asymmetric septal hypertrophy may be visualized sonographically (often seen in fetuses of diabetic mothers).
Asymmetric septal hypertrophy has been identified antenatally (1).
www.fetalultrasound.com /online/text/7-041.HTM   (274 words)

  
 eMedicine - Cardiomyopathy, Hypertrophic : Article Excerpt by: Charles Berul, MD
The hallmark of the disorder is myocardial hypertrophy that is inappropriate, often asymmetric, and occurs in the absence of an obvious inciting hypertrophy stimulus.
Although any region of the left ventricle (LV) can be involved, hypertrophy frequently involves the interventricular septum, which results in an obstruction in the LV outflow tract.
The pressure gradient appears to be related to further narrowing of the outflow tract, already made small by the marked asymmetric septal hypertrophy and the possibly abnormally located mitral valve, by systolic anterior motion of the mitral valve against the hypertrophied septum.
www.emedicine.com /ped/byname/cardiomyopathy-hypertrophic.htm   (621 words)

  
 Isolation and characterization of myosin from subjects with asymmetric septal hypertrophy -- Maron et al. 40 (5): 468 ...
Isolation and characterization of myosin from subjects with asymmetric septal hypertrophy -- Maron et al.
Isolation and characterization of myosin from subjects with asymmetric septal hypertrophy
subjects with ASH is not expressed in the particular structural and
circres.ahajournals.org /cgi/content/abstract/40/5/468   (186 words)

  
 Coexistence of asymmetric septal hypertrophy and aortic valve disease in adults -- Raj et al. 34 (1): 91 -- Thorax
Coexistence of asymmetric septal hypertrophy and aortic valve disease in adults -- Raj et al.
Coexistence of asymmetric septal hypertrophy and aortic valve disease in adults
ASH was confirmed at the time of aortic valve replacement in two of
thorax.bmjjournals.com /cgi/content/abstract/34/1/91   (174 words)

  
 MedlinePlus Medical Encyclopedia: Hypertrophic cardiomyopathy
Cardiomyopathy - hypertrophic (HCM); IHSS; Idiopathic hypertrophic subaortic stenosis; Asymmetric septal hypertrophy; ASH; HOCM; Hypertrophic obstructive cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a form of cardiomyopathy, a condition in which the heart muscle to become thick.
Hypertrophic cardiomyopathy is often asymmetrical, meaning one part of the heart is thicker than the other parts.
www.nlm.nih.gov /medlineplus/ency/article/000192.htm   (944 words)

  
 Save an Athlete.org | The Issue of Sudden Cardiac Arrest and Our Youth
The syndrome is known as Hypertrophic Obstructive Cardiomyopathy (H.O.C.M.) or Asymmetric Septal Hypertrophy (A.S.H.) or Idiopathic Hypertrophic Subaortic Stenosis (I.H.S.S.).
A Restrictive Cardiomyopathy, the rarest form of cardiomyopathy, is a condition in which the walls of the lower chambers of the heart (the ventricles) are abnormally rigid and lack the flexibility to expand as the ventricles fill with blood.
Left Ventricular Hypertrophy (LVH) is an enlargement of the left pumping chamber of the heart and may be due to several different things.
www.saveanathlete.com /the_issue.cfm   (2295 words)

  
 Asymmetric septal hypertrophy - WrongDiagnosis.com
The term Asymmetric septal hypertrophy can be used for:
Other terms that may be related to Asymmetric septal hypertrophy:
The description of Asymmetric septal hypertrophy may also be used for the following terms:
www.wrongdiagnosis.com /medical/asymmetric_septal_hypertrophy.htm   (260 words)

  
 Asymmetric Septal Hypertrophy, Cardiomyopathy
Asymmetric hypertrophy of the interventricular septum, conspicuous in the mid portion, measuring 2.0 cm in width, and dilatation of both the ventricles of the hypertrophic heart (380 g/ 44 kg = circa 8.6, *152 g).
Histologically, severe disarray and disorganization of myocardial fibers showing abnormal branching, ovarlapping, hypertrophy and contraction band necrosis with hyperchromatic and bizarre nuclei, and accompanying interstitial edema and fibrosis (plexiform fibrosis).
Molecular-genetic studies have recently demonstrated mutations in the beta cardiac myosin heavy-chain genes on chromosome 14 in some but not all families with familial hypertrophic cardiomyopathy, in which Watkins et al (Harvard Medical School) identified seven different missense mutations in that gene in 12 of 25 families (or 48 %) with the disease.
members.aol.com /drhasegawa/cpc9209.htm   (474 words)

  
 CiteULike: Cardiac involvement in Friedreich's ataxia: a clinical study of 75 patients.   (Site not responding. Last check: 2007-11-03)
Electrocardiograms revealed ST-T wave abnormalities in 79%, right axis deviation in 40%, short PR interval in 24%, abnormal R wave in lead V1 in 20%, abnormal inferolateral Q waves in 14% and left ventricular hypertrophy (voltage and repolarization criteria) in 16%.
Echocardiograms revealed concentric left ventricular hypertrophy in 11%, asymmetric septal hypertrophy in 9% and globally decreased left ventricular function in 7%.
Progression from a normal echocardiogram to concentric left ventricular hypertrophy, asymmetric septal hypertrophy or globally decreased left ventricular function was identified in one patient in each category, although the study was not designed for longitudinal follow-up.
www.citeulike.org /user/abelmagalhaes/article/717393   (479 words)

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