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| | Life before model systems: General zoology at August Weismann's institute American Zoologist - Find Articles |
 | | He reminds us of and endorses what Hans Krebs once called the "[August] Krogh principle," named after the famous Danish physiologist, who wrote that "For a large number of problems there will be some animal of choice or a few such animals on which it can be most conveniently studied" (Krebs, 1975; Krogh, 1929, p. |
 | | Krogh thereby implied that convenience, in a broad sense, and specific problem solving, not a presumptive general model, had and should guide the choice of an organism in research (Gest, 1995). |
 | | Developmental biologist Jessica Bolker has provided a thoughtful analysis of some of the shortcomings of a model systems approach: the unavoidable biases in the organism selection process, the confusion of experimental convenience for universality, and a frequent disregard of phylogenetic reality are among the dangers she discusses (Bolker, 1995). |
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