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Topic: Autoimmune disease


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  What is Autoimmunity?: Johns Hopkins Autoimmune Disease Research Center
Autoimmune diseases are, thus, defined when the progression from benign autoimmunity to pathogenic autoimmunity occurs.
Autoimmune diseases are among the ten leading causes of death among women in all age groups up to 65.
Autoimmune diseases of the blood, for example, are treated by hematologists, those of the nervous system by neurologists, those of the endocrine system by endocrinologists and those of the joints and muscles by rheumatologists.
autoimmune.pathology.jhmi.edu /whatisautoimmunity.html   (974 words)

  
 Autoimmune Disease
Diseases arising from a deficiency in complement: When an antigen and antibody react they may activate a series of serum enzymes (the complement system) whose end result is either the lysis (breakup) of the antigen molecule or to make it easier for phagocytic cells like the macrophages to destroy it.
Autoimmune thyroiditis (hypothyroidism) is generally found with the other autoimmune diseases or may occur by itself.
The reported incidence of autoimmune disease is on the rise, and there is some debate as to whether this is because it is really more common or because we are better at detecting it.
bccc.pair.com /autoimmu.htm   (2407 words)

  
 AUTOIMMUNE DISEASE IN WOMEN - The Facts
Autoimmune diseases also seem to have a genetic component, but, mysteriously, they can cluster in families as different illnesses.
This is a broad and heterogeneous group of diseases characterized by inflammation and damage to the blood vessels, thought to be brought on by an autoimmune response.
The programs and activities in autoimmune diseases of the PHS Office on Women's Health, joined with initiatives and programs across the agencies and office of the Department of Health and Human Services, are providing a solid foundation from which to increase knowledge about autoimmune disorders in women.
www.aarda.org /women.html   (1673 words)

  
  Autoimmune3   (Site not responding. Last check: )
Diseases arising from a deficiency in complement: When an antigen and antibody react they may activate a series of serum enzymes (the complement system) with the end result being either lysis (breakup) of the antigen molecule or a process which makes it easier for phagocytic cells like the macrophages to destroy it.
The reported incidence of autoimmune disease is on the rise, and there is some debate as to whether this is because it is really more common or because we are better at detecting it.
Hormonal changes can trigger autoimmune disease, and for this reason it is wise to avoid giving vaccinations before (30 days before expected onset) during or immediately after a bitch's estrus (heat) period.
www.beaconforhealth.org /Autoimmune3.htm   (4140 words)

  
 Autoimmune Disease treatment : by Ray Sahelian, M.D., herbs and supplements for autoimmune disease
This islet "autoimmunity" is decreased by high dietary levels of omega-3's in children with a family history of type 1 diabetes or who have a genetic pattern linked to the condition.
Dizziness, fatigue, malaise and a low-grade fever are among autoimmune disease symptoms associated with collagen vascular—type of autoimmune diseases.
The effects of flavones were the same for human and murine autoreactive T cells, stressing the usefulness of animal models of autoimmunity for further studies on the effects of flavonones on autoimmune diseases.
www.raysahelian.com /autoimmunedisease.html   (2297 words)

  
 Autoimmune Diseases  What Are Autoimmune Diseases
Most autoimmune diseases strike women more often than men; in particular, they affect women of working age and during their childbearing years.
Thus, the social, economic, and health impact from autoimmune diseases is far-reaching and extends not only to family but also to employers, co-workers, and friends.
Autoimmune diseases are often chronic, requiring lifelong care and monitoring, even when the person may look or feel well.
www.tjclarkminerals.com /Diseases/d_autoimmune_diseases.htm   (739 words)

  
 Autoimmune Diseases
Are chronic fatigue syndrome and fibromyalgia autoimmune diseases?
Autoimmune diseases can affect connective tissue in your body (the tissue which binds together body tissues and organs).
Autoimmune disease can affect many parts of your body, like your nerves, muscles, endocrine system (system that directs your body’s hormones and other chemicals), and digestive system.
www.4woman.gov /faq/autoimmune.htm   (1719 words)

  
 NPI- Main Articles - Autoimmune Disease
This concept of autoimmunity as the cause of human illness is relatively new, and it was not accepted in the mainstream of medical thinking until the 1950s and 1960s, reported the Autoimmune Disease Research Center at Baltimore-based Johns Hopkins.
Autoimmune diseases are defined as diseases in which the progression from benign autoimmunity to pathogenic autoimmunity occurs.
Crohns disease and UC are both mainly developed in areas with high bacterial concentrations, such as the terminal ileum and cecum in Crohns disease and the rectum in ulcerative colitis.
www.naturalproductsinsider.com /articles/441autoimmune.html   (4162 words)

  
 Autoimmune Disease Infertility
Specific autoimmune diseases are, at times, difficult to diagnose, especially in the early stages of the disease, when symptoms and laboratory data may not yet be specific enough.
Since autoimmune diseases are often chronic, they may require lifelong care and monitoring, even when the person may look and feel well.
As the causes of autoimmune diseases are not well understood, it is not surprising that we still lack specific treatments for the various conditions.
www.centerforhumanreprod.com /autoimmune_disease.html   (757 words)

  
 lupus an autoimmune disease information.
T is thought that autoimmune diseases, such as lupus, occur when a genetically susceptible individual encounters an unknown environmental agent or trigger.
Upus is a condition of chronic inflammation caused by an autoimmune disease.
Autoimmune diseases are illnesses which occur when the body's tissues are..
www.lawnet.com.au /l/lupus_an_autoimmune_disease.html   (142 words)

  
 Life With an Autoimmune Disease
Your first symptoms of an autoimmune disease may be general, such as fatigue, low-grade fever, and difficulty concentrating, making autoimmune diseases difficult to diagnose at first.
That such different-seeming diseases as psoriasis and diabetes could stem from a common cause actually is a relatively new notion, according to Noel R. Rose, MD, PhD, professor of molecular microbiology and immunology and pathology at the Johns Hopkins University in Baltimore.
Another common characteristic of all autoimmune diseases is that it is thought that an outside agent is required to start the process.
www.webmd.com /content/article/76/90216.htm   (590 words)

  
 Autoimmune Disease @ Suite101: Diagnosis, treatment, triggers, prognosis and new and traditional lab testing for ...
Various symptoms in autoimmune diseases, including endocrine imbalances and pain, contribute to low libido in autoimmune disease.
Cytokines include a number of different proteins that modulate the immune response; cytokines contribute to symptoms and their severity in autoimmune disease.
Evidence for the role of vitamin D deficiency in autoimmune disease continues to grow.
autoimmunedisease.suite101.com   (486 words)

  
 Immunologic Diseases -- Autoimmune Diseases
For instance, the autoimmune reaction is directed against the brain in multiple sclerosis and the gut in Crohn's disease.
Most autoimmune diseases strike women more often than men, particularly affecting women of working age and during their childbearing years.
Certain diseases such as psoriasis can occur among several members of the same family, suggesting that a specific gene or set of genes predisposes a family member to psoriasis.
www.niaid.nih.gov /final/immds/immdeff.htm   (350 words)

  
 Autoimmune disease definition - Medical Dictionary definitions of popular medical terms easily defined on MedTerms
Autoimmune disease: An illness that occurs when the body tissues are attacked by its own immune system.
Patients with autoimmune diseases frequently have unusual antibodies circulating in their blood that target their own body tissues.
It is felt that the estrogen of females may influence the immune system to predispose some women to autoimmune diseases.
www.medterms.com /script/main/art.asp?articlekey=2402   (251 words)

  
 Autoimmune disease triggered if T cells miss a single protein early on
The discovery, from a mouse model of a human autoimmune condition, suggests that effective strategies to treat autoimmune disease should target not only the "peripheral" sites where autoimmune disease is active, but also the thymus -- the organ where T cells and self-proteins, or self-antigens, first interact.
T cell soldiers encounter the body's full array of proteins in the thymus, and those T cells with receptors that recognize "self" proteins, or antigens, normally are purged to avoid autoimmune attacks in the body later on.
A clue to how the elimination process is controlled came from previous work involving a protein in the cell nucleus called Aire (for autoimmune regulator), which regulates the expression of some 300 to 1,000 antigens in the thymus.
www.eurekalert.org /pub_releases/2006-11/uoc--adt112106.php   (973 words)

  
 Product Candidates - Autoimmune Disease
The resulting conditions, known as autoimmune diseases, often allow B cells to produce antibodies that attack healthy cells and tissues, including vital organs.
Antibody-mediated autoimmune diseases are potentially life-threatening conditions that affect millions of individuals worldwide.
In response to the unmet need for effective and safe therapeutic approaches to antibody-mediated diseases, La Jolla Pharmaceutical Company is applying its proprietary Tolerance Technology® to the development of a novel class of compounds, called Toleragens®, with the goal of inactivating targeted B cells, and stopping them from producing harmful antibodies.
www.ljpc.com /product_research.html   (334 words)

  
 Autoimmune Disease Update
In Graves' disease, the thyroid gland is primarily affected.
Approximately 3-5 percent of the population are affected by autoimmune diseases.
Factors which predispose to the development of autoimmunity include genetic factors, age of the individual and environmental factors such as stress and infectious agents.
www.suite101.com /article.cfm/graves_disease/85212   (555 words)

  
 Autoimmune Diseases
Also referred to as autoimmune thyroiditis and chronic lymphocytic thyroiditis, is a chronic inflammatory glandular autoimmune disease.
An autoimmune reaction to proteins in the thyroid is the underlying cause of Hashimoto's thyroiditis.
Although men and women of any age can develop this disease, it is most common in women between the ages of 30 or 50 where the ratio of female to male is fifty to one.
www.angelfire.com /extreme3/mikalehealth   (673 words)

  
 Autoimmune Hepatitis   (Site not responding. Last check: )
Autoimmune hepatitis is a disease in which the body's immune system attacks liver cells.
Type II autoimmune hepatitis is less common, typically affecting girls ages 2 to 14, although adults can have it too.
Autoimmune hepatitis is a long-term disease in which your body's immune system attacks liver cells.
digestive.niddk.nih.gov /ddiseases/pubs/autoimmunehep/index.htm   (1258 words)

  
 Some Examples of Autoimmune Processes
Cold agglutinin disease is an acquired autoimmune hemolytic anemia due to an IgM autoantibody usually directed against the I antigen on red blood cells.
Chronic active hepatitis (CAH), or autoimmune hepatitis, is a chronic inflammatory autoimmune disease of the liver.
Autoimmune Addison's disease is an uncommon autoimmune disease, characterized by chronic and insufficient functioning of the outer layer of the adrenal gland.
www.valdezlink.com /pages/autoimmune.htm   (3931 words)

  
 Dog Owner's Guide: Autoimmune diseases
Secondly, most autoimmune diseases are treated with very high doses of corticosteroids or other immunosuppressive drugs to lower the immune response, much like a kidney transplant patient takes anti-rejection drugs.
Unfortunately, due to the insidious nature of autoimmune diseases, progeny from your kennel may not be diagnosed until after you have retired the suspect dogs from your breeding program.
As in other autoimmune diseases previously discussed, the primary goal of therapy is to suppress the body's immune response with large doses of systemic glucorticoids.
www.canismajor.com /dog/autoimmn.html   (3045 words)

  
 NIH Guide: AUTOIMMUNE ENDOCRINE DISEASE
People with one autoimmune endocrine disease are at increased risk for another of these disorders, as are family members of patients with autoimmune endocrine disease.
As a result of this workshop several key research issues relevant to autoimmune endocrine diseases were identified, including the underlying nature of autoimmunity, the basis of increased incidence in women, and potential therapeutic approaches to autoimmune diabetes and thyroid disease.
For autoimmune thyroid diseases, several of the antigens that are involved in the immune system responses, including the TSH receptor for Graves' disease and thyroid peroxidase (TPO) for Hashimoto's thyroiditis, have been identified.
grants.nih.gov /grants/guide/pa-files/PA-93-114.html   (1178 words)

  
 What is Autoimmune Disease?
The immune system is made up of white blood cells, organs and structures whose mission it is to identify and destroy disease causing organisms such as bacteria, viruses, fungi, and parasites.
In autoimmune diseases, a foreign antigen mimics a group of self proteins, and then when the immune system mounts an attacking response against these foreign invaders, it inadvertently attacks and destroys self tissues.
Most treatment of autoimmune diseases is usually aimed at lessening the severity of symptoms and replacing the missing hormones when a gland is destroyed.
www.healinglight.com /autoimmune/whatis.html   (1135 words)

  
 type of autoimmune disease information.
This is a long needed support page for all people afflicted with an autoimmune disease and their caregivers.
In a few types of autoimmune disease (such as rheumatic fever), a bacteria or virus triggers an immune response, and the antibodies or T-cells attack normal..
The types of autoimmune disease treated at the SCCA with a stem-cell..
www.lawnet.com.au /t/type_of_autoimmune_disease.html   (119 words)

  
 Photopheresis as a Treatment of Autoimmune Disease and Graft-versus-Host Disease
The use of photopheresis as a treatment of autoimmune disease is based on the premise that the pathogenic lymphocytes form an expanded clone of cells, which are then damaged when exposed to light.
However, although scleroderma and other autoimmune diseases are associated with the presence of circulating antibodies, it is not certain how these antibodies are related to the pathogenesis of the disease, and as discussed below, photopheresis is not associated with consistent changes in autoantibody levels.
The use of photopheresis as a treatment of graft-versus-host disease (GVHD) after a prior allogeneic stem cell transplant is based on the fact that GVHD is similar to autoimmune disease in that it too is an immunologically mediated disease.
www.regence.com /trgmedpol/medicine/med84.html   (1499 words)

  
 Strategic Analysis of the Autoimmune Disease Diagnostics Market in Europe
The high double digit growth rate in the segment for autoimmune diseases tests other than thyroid and rheumatoid arthritis is driving the autoimmune testing market in Europe.
The variety of potential therapies for autoimmune diseases is expected to expand rapidly in the next decade based on the efforts of leading pharmaceutical companies.
The total European autoimmune disease diagnostics market was worth $440 million in 2004 and is all set for a sizeable growth to reach almost $700.0 million by 2011.
www.marketresearch.com /product/display.asp?productid=1070499&partnerid=901625821   (482 words)

  
 Allergies
This is an autoimmune disorder in which the patient develops antibodies against his or her own platelets (thrombocytes).
The role of antibodies (of the IgG class) in this disorder is demonstrated by the presence of the disease in the newborn babies of mothers with the disorder.
In this disease, T cells initiate the destruction of the insulin-producing beta cells of the islets of Langerhans in the pancreas.
users.rcn.com /jkimball.ma.ultranet/BiologyPages/A/Allergies.html   (2788 words)

  
 Scientists Spot Key Autoimmune Disease Genes - Disease Prevention and Wellness Information to Improve Your Health on ...
MONDAY, Jan. 22 (HealthDay News) -- The identification by U.S. scientists of genes thought to be key to autoimmune disorders could be a big step toward new treatments for these illnesses, which include lupus, rheumatoid arthritis and type 1 diabetes.
Cells called regulatory T-cells are supposed to help keep the immune system in check, but in autoimmune disease, these mechanisms can fail.
The finding could have important implications for research into autoimmune disease and even cancer, experts say.
www.medicinenet.com /guide.asp?s=rss&a=79151&k=Senior_Health_General   (811 words)

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