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Topic: Autologous


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In the News (Mon 7 Dec 09)

  
  Autologous definition - Medical Dictionary definitions of popular medical terms easily defined on MedTerms
Autologous: In blood transfusion and transplantation, a situation in which the donor and recipient are the same person.
Patients scheduled for non-emergency surgery may be autologous donors by donating blood for themselves that will be stored until the surgery.
An autologous graft is providing a graft, for example of skin, to yourself.
www.medterms.com /script/main/art.asp?articlekey=13210   (218 words)

  
  Umbilical cord blood banks for autologous use or for research
In 50% of autologous grafts, patients are over the age of 50, and patients under the age of 20 represent 10% of that population.
Although organising the preservation of cord blood for autologous purposes must of necessity compare favourably with allogenic bank procedures as regards stringency and safety, autologous therapeutic indications are not at all comparable to those of allogenic procedures, and in the present state of scientific progress, are very nearly virtual.
Autologous transplant indications are more frequent for adults than for children : the International Bone Marrow Transplant Registry (IBMTR/ABMTR http://www.ibmtr.org/newsletter/newsletter.asp) reports that between 1997 and 2000 ~5% of autografts concerned patients under the age of 20, whereas more than 50% were performed on patients over the age of 50.
www.ccne-ethique.fr /english/avis/a_074.htm   (1779 words)

  
 dtm autologous donations
Autologous donors are those who store one or more pints of their own blood prior to a scheduled treatment or surgery that may require a transfusion.
Because autologous blood is the safest transfusion available, NIH employees may also donate their own blood at the NIH Blood Bank if they are having surgery at another hospital.
Autologous donors can give as often as once a week but donations must be discontinued at least a week before surgery.
www.cc.nih.gov /dtm/dtm_autologous_donations.htm   (474 words)

  
 Transfusion Alert: Use of Autologous Blood
Thus, the adding of unused autologous blood to the inventory would have little impact on the overall blood supply and should not be considered a justification for requesting autologous donations from patients who are not likely to require transfusion.
For example, the transfusion of autologous RBCs to the slightly or non-anemic patient or the use of autologous fresh frozen plasma in the absence of coagulopathy is inappropriate.
Autologous blood transfusion techniques should be used for eligible patients likely to require transfusion but should not be started for procedures in which transfusion is unlikely.
www.nhlbi.nih.gov /health/prof/blood/transfusion/logo.htm   (5582 words)

  
 Cormack-AUTOLOGOUS BLOOD DONATION
Autologous blood is defined as blood drawn from one individual to be given back to that individual as the need for transfusion arises.
Autologous blood donation programs for high risk patients have been in existence in the United States for many years in response to concerns associated with post transfusion hepatitis and HIV infection.
The incidence of mild reactions is estimated to be 1.13-4.8% in volunteer donors (9) and 4.8% in autologous donation patients (10).
www.bloodloc.com /bib17.htm   (1502 words)

  
 CureHodgkins.com, Autologous Stem Cell Transplant
In an autologous BMT the patient is both the donor and the recipient of the bone marrow.
Autologous BMTs have expanded treatment options for thousands of patients diagnosed with life-threatening diseases such as Hodgkin's disease and non-Hodgkin's lymphoma, breast cancer, ovarian cancer, testicular cancer and pediatric solid tumors such as neuroblastoma.
An autologous BMT enables physicians to "rescue" the patient from the effects of high-dose chemotherapy and/or radiation treatment by replacing the destroyed bone marrow.
www.curehodgkins.com /hodgkins_resources/transplant.html   (603 words)

  
 October 1995 - Autologous and Directed Blood Donations
Autologous donation can be utilized in children weighing at least 65 pounds and is generally a safe procedure, even for elderly patients.
Autologous Donation Technique: Autologous units may be stored and used as whole blood, but are usually processed into packed red blood cells; fresh frozen plasma may also be prepared from the latter.
Unused autologous blood is stored for the patient’s peri-operative needs until the unit outdates or until the patient is discharged (according to specific hospital policy); it is then discarded.
www.itxm.org /TMU1995/tmu10-95.htm   (1083 words)

  
 Autologous blood transfusion [Sep 1996; 31-5]
In Bandolier 17 you quote a study from the New England Journal of Medicine (332:719, 1995) purporting to demonstrate that autologous transfusion is not cost-effective.
The two randomised trials comparing autologous with allogenic transfusion were done in colorectal surgery, so Blumberg and colleagues [1] based their analyses on case-control studies in their own hospital setting, in which autologous blood collection is common.
Because present practice of autologous transfusion did not allow a direct comparison of allogenic with autologous transfusion, records from a previous study were examined for a comparison of 33 patients having 2 or 3 units of autologous blood only and 49 patients having 2 or 3 units of allogenic blood only.
www.jr2.ox.ac.uk /bandolier/band31/b31-5.html   (799 words)

  
 Autologous Summary
In blood banking terminology, autologous refers to a blood donation marked for use by the donor, often in an upcoming scheduled surgery.
Autologous blood is stored at one specific hospital clearly labelled for use by one specific patient; if it is not used by that patient, it is discarded.
Autologous donation is also not suitable for patients who are medically unable to or not advised to give blood, such as cardiac patients or small children and infants.
www.bookrags.com /Autologous   (684 words)

  
 [No title]   (Site not responding. Last check: )
The most common autologous donation is the preoperative donation of blood for possible transfusion back to the donor during elective surgery.
Autologous donation is most often employed in surgery on bones, blood vessels, the urinary tract, and the heart, when the likelihood of transfusion is high.
Forty-four percent of autologous donations are unused by the autologous donor.
www.aabb.org /Content/About_Blood/Facts_About_Blood_and_Blood_Banking/fabloodautoallo.htm   (766 words)

  
 IMF: Autologous Bone Marrow And Stem Cell Transplantation, part 1
An autologous peripheral blood stem cell transplant is a procedure that replenishes the supply of normal cells that are destroyed by high dose chemotherapy and/or radiation therapy.
The word autologous means that the blood is collected from the patient, not from a relative or a volunteer donor.
Autologous transplantation is a complex process that can take weeks to months to complete.
www.myeloma.org /myeloma/kb_index.jsp?type=detail&id=37   (3092 words)

  
 Autologous Chondrocyte Transplantation
Autologous chondrocyte transplantation for the treatment of cartilage defects is considered investigational.
The authors state that further investigation is needed to determine if it is the transplanted autologous chondrocytes or the mesenchymal cells of the periosteal flap that develop in to the cellular component of the regenerated tissue.
Autologous chondrocyte transplantation in osteochondral lesions of the ankle joint.
www.regence.com /trgmedpol/surgery/sur87.html   (4183 words)

  
 Autologous & Designated Blood Donation
In the late 1980s the transfusion services noticed a steady increase in the number of requests for both autologous and designated donation (where a patient can select their own donors and ensure that blood is kept exclusively for the patient).
At the WPBTS all the autologous donations follow a routine screening process and are tested for haemoglobal levels, HIV antibody, p24 antigen, hepatitis Band C, and syphilis.
Autologous donors who test positive for HIV or hepatitis will not be accepted on the programme, as the transfusion services are concerned about the risk of storing positive units of blood in their blood bank.
members.tripod.com /cab94/wpbts01.htm   (965 words)

  
 Autologous Blood Deposits and Transfusions
Using autologous blood eliminates the possibilities of infecting the recipient with blood-borne viral diseases; prevents alloimmunization to erythrocyte, leukocyte, and platelet antigens; and, in general, saves the patient from all potential short- and long-term, alleged consequences of allogeneic blood transfusions.
Even though autologous blood deposits and transfusions have become a routine measure of standard of care, the percentage of patients undergoing elective surgery who avail themselves of this option is still rather low due to the lack of information or other logistical problems.
Issues such as the probability of needing a transfusion during surgery, the number of autologous blood deposits for the anticipated surgery, and the possibility for perioperative phlebotomy with hemodilution should be discussed with and explained to the patient.
www3.mdanderson.org /~citm/H-92-10.html   (1892 words)

  
 Autologous Blood Donation Basics - BloodBook, Blood Information for Life
Autologous Blood donation should be the transfusion therapy of choice, or at least, fully and carefully considered.
Preoperative autologous Blood donation, transfusion and storage (PABD): units of Blood are drawn from a patient usually starting (in the short term case) three to five weeks before an elective surgical procedure and stored for transfusion at the time of the surgery.
Autologous self stored Blood (Blood banking): your own Blood is preserved in a frozen state for use by you or your designee at a later time, in case your need of a Blood transfusion arises.
www.bloodbook.com /autolog-1.html   (2084 words)

  
 Autologous Stem Cell Transplants
Autologous stem cell transplants refer to stem cells that are collected from an individual and given back to that same individual.
Autologous transplants are also referred to as autografts, and are by far the most common type of transplant performed in myeloma patients today.
High-dose chemotherapy and autologous transplant is considered by many to be a standard of care for patients up to the age of 65.
www.multiplemyeloma.org /treatments/3.03.02.html   (2472 words)

  
 Autologous Blood Donation Information on Healthline
Autologous blood donation is the process of donating one's own blood prior to an elective surgical or medical procedure to avoid or reduce the need for an allogeneic blood transfusion (from a volunteer blood donor).
Autologous donation is indicated for an elective surgical or medical procedure in which the likelihood of a blood transfusion is high.
Acute normo-volemic hemodilution (ANH) is a variant of autologous donation in which a volume of the patient's blood is removed directly before surgery and replaced with fluids so that any blood lost during surgery has a lower red blood cell count (i.e., the red blood cells have been diluted).
www.healthline.com /galecontent/autologous-blood-donation   (855 words)

  
 Carticel (Autologous Cultured Chondrocytes) Package Insert   (Site not responding. Last check: )
Autologous cultured chondrocytes, the Carticel product, are derived from in vitro expansion of autologous chondrocytes harvested from a patient's normal, femoral articular cartilage.
To help differentiate the effects of the autologous cultured chondrocyte implantation procedure from those of debridement alone, an analysis was performed on 22 patients who had failed prior debridement and had a follow-up period after autologous cultured chondrocyte implantation which was greater than the time period to failure of their initial debridement.
Registry data on 891 patients who received implantation of autologous cultured chondrocytes were derived from voluntary reporting by surgeons and do not include those from routine arthroscopy; 131 patients had a follow up of at least 18 months.
www.fda.gov /cber/label/autogen030200LB.htm   (2484 words)

  
 The Leukemia & Lymphoma Society : The Society - News from 411Cancer
Autologous stem cell transplants involve the collection of patient's stem cells prior to treatment and re-infusion following high-dose therapy to restore depleted blood cell levels.
The double transplant patients were treated with high-dose melphalan and autologous stem cells followed by high-dose melphalan and total body irradiation and an additional autologous stem cell infusion.
Patients with multiple myeloma under the age of 65 who have not responded well to either induction therapy or a first autologous transplant may wish to speak with their physician about the risks and benefits of participating in a clinical trial further evaluating a double transplant.
www.leukemia-lymphoma.org /all_news_detail.adp?item_id=223206&cat_id=140   (714 words)

  
 CBBS: Does Anyone Use an Abbreviated Questionnaire for Autologous Donors?   (Site not responding. Last check: )
We use an abbreviated questionnaire for autologous donors and a consent form that is different from the consent form used for allogeneic donors.
At our center autologous donors answer only a few questions about their health, since we are not going to crossover their blood, and all we are interested in is whether or not they can tolerate the procedure.
We use a shortened history for autologous donors and only ask 11 questions, which are the ones that refer to donor safety i.e.
www.cbbsweb.org /enf/1999_2000/ad_hx.html   (843 words)

  
 Hematicus - Definitions
is a technique used by anesthesiologists during surgery to conserve autologous blood.
Preservation of patient's "native" or "their own" blood supply and avoidance of allogeneic blood transfusion are 2 hallmarks of autologous blood transfusion.
Autologous blood conservation is a blossoming field, covering many different medical specialties and health care areas.
www.hematicus.com /Defines.html   (322 words)

  
 Autologous
Autologous means “self donation” and refers to donating blood for your own surgery.
Autologous donations may only be drawn as early as 30 days prior to surgery and no less than 5 days prior to surgery.
After an autologous blood unit has been successfully collected, it is carefully labeled with a specific autologous label with the patient’s name to identify it as an autologous unit belonging to a specific patient.
www.bloodntissue.org /Autologous.asp   (417 words)

  
 Clinical Trial: Chemotherapy Followed By Autologous Natural Killer Cells and Aldesleukin in Treating Patients With ...
Determine the ability of the administration of autologous natural killer cells and aldesleukin after a nonmyeloablative lymphodepleting preparative regimen to mediate tumor regression in patients with metastatic melanoma or renal cell cancer.
Leukapheresis: Patients undergo apheresis to collect peripheral blood lymphocytes that are used for in vitro generation of autologous natural killer (NK) cell lymphocytes.
Autologous NK cell infusion: Patients receive autologous NK cells IV over 20-30 minutes on day 0.
www.clinicaltrials.gov /ct/show/NCT00354055?order=4   (671 words)

  
 eMedicine - Hematopoietic Stem Cell Transplantation : Article by E Anders Kolb, MD   (Site not responding. Last check: )
Autologous transplantation refers to the use of the patient's own stem cells as a rescue therapy after high-dose myeloablative therapy.
Autologous transplantation is the standard of care for relapsed Hodgkin disease and primary refractory Hodgkin disease.
Autologous transplantation is the standard of care for relapsing or refractory diffuse, large B-cell lymphoma and relapsing or refractory follicular lymphoma.
www.emedicine.com /ped/topic2593.htm   (3877 words)

  
 Patient Care: Autologous Blood Donations   (Site not responding. Last check: )
An Autologous Blood Donation is a procedure that allows you to donate blood to yourself prior to an upcoming operation, with your physician's approval.
The Autologous Donation process is similar to the process for volunteer donations.
Autologous blood can be collected at the Central FGBA Community Donor Center at 536 West 10th Street, by appointment only.
www.igiveblood.com /patient/default.htm   (279 words)

  
 2005 Annual Meeting Information - AAOS   (Site not responding. Last check: )
Autologous platelet concentrates have been available for several years, however there is a lack of human clinical data.
Autologous concentrated growth factors in combination with autologous bone graft may have a positive influence on the syndesmosis fusion rate.
Autologous concentrated growth factors appear to make a significant positive difference in the syndesmosis union rate in total ankle replacements.
www.aaos.org /education/anmeet/anmt2005/poster/P185.asp   (263 words)

  
 NHL Transplant Outcomes -- patient information
Autologous transplant outcomes for patients with diffuse large cell lymphoma or follicular lymphoma are shown in Figures 1 and 2.
Whether an autologous transplant is recommended at first remission depends on the type of lymphoma and a patient's specific risk factors.
This risk has balanced or outweighed the higher risk of relapse after an autologous transplant, leading to survival rates that are similar or higher for autologous transplants.
www.marrow.org /PATIENT/Undrstnd_Disease_Treat/Lrn_about_Disease/NHL/NHL_Transplant_Outcomes/index.html   (1319 words)

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