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Topic: Axial osteosclerosis

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	Axial osteosclerosis - WrongDiagnosis.com
		Axial osteosclerosis: A rare bone abnormality involving patches of increased bone density which tend to occur in the spine, pelvis and the ball part of the hip joint.
		Axial osteosclerosis is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
		This means that Axial osteosclerosis, or a subtype of Axial osteosclerosis, affects less than 200,000 people in the US population.
	www.wrongdiagnosis.com /a/axial_osteosclerosis/intro.htm (347 words)

	Variability in Radiographic Appearance of Fluorosis
		Osteosclerosis was present in the central area of the pelvis while the lateral part showed considerable osteopenia.
		Human patients are usually diagnosed as having osteosclerosis whereas animals are described as having osteoporosis or 'osteomalacia'.
		Spinal osteosclerosis resulting from chronic fluoride intoxication may be expected to divert calcium preferentially to the spinal column at the expense of limb bones.
	www.fluoridealert.org /health/bone/fluorosis/variability/radiographic.html (1912 words)

	Medcyclopaedia - Osteosclerosis (Site not responding. Last check: 2007-11-01)
		Osteosclerosis may accompany a great variety of disorders, including hyperparathyroidism or renal osteodystrophy, osteoarthritis, sickle cell anaemia, Pagets disease, systemic mastocytosis, skeletal metastasis, myelofibrosis, oxalosis, leukaemias and osteomyelitis.
		Osteosclerosis of the vertebral bodies produces changes at both superior and inferior aspects, leading to an appearance termed the rugger jersey spine.
		The inactive stage may be characterized by the alterations in the cranium (cotton wool appearance, thickening of the cranial vault, basilar invagination), spine (ivory vertebra, picture frame vertebral body), pelvis (thickening of the pelvic ring, focal or diffuse radiodense lesions), and long tubular bones (coarse trabeculae, widened and deformed bone).
	medcyclopaedia.com /library/topics/volume_iii_1/o/osteosclerosis.aspx (227 words)

	Variability in Radiographic Appearance of Fluorosis
		Osteosclerosis was present in the central area of the pelvis while the lateral part showed considerable osteopenia.
		Human patients are usually diagnosed as having osteosclerosis whereas animals are described as having osteoporosis or 'osteomalacia'.
		Spinal osteosclerosis resulting from chronic fluoride intoxication may be expected to divert calcium preferentially to the spinal column at the expense of limb bones.
	fluoridealert.org /health/bone/fluorosis/variability/radiographic.html (1912 words)

	Definitions bone diseases and dental fluorosis
		OSTEOSCLEROSIS "an abnormal increase in the density of bone tissue.
		The total quantity of ingested fluoride is the single most important factor which determines the clinical course of the disease which is characterized by immobilization of joints of the axial skeleton and of the major joints of the extremities.
		A combination of osteosclerosis, osteomalacia and osteoporosis of varying degrees as well as exostosis formation characterizes the bone lesions.
	www.fluoridation.com /definit.htm (2058 words)

	Fluorides and Fluoridation - Case Reports
		Osteosclerosis was seen in 54 patients (43%), and osteopenia was seen in 51 patients (40%).
		Subsequent investigation disclosed the cause of her osteosclerosis to be fluorosis secondary to the ingestion of well water containing 429 mumol/L of fluoride (recommended levels, 11 to 58 mumol/L).
		She was subsequently found to have fluorosis as shown by radiological osteosclerosis in vertebrae and pelvis with histological changes of osteomalacia on bone biopsy and a high bone fluoride content.
	www.rvi.net /~fluoride/s13.htm (8054 words)

	Fluoride's Differential Effect on Bone Density
		"The dramatic increase in the predominantly trabecular bone of the axial skeleton during fluoride therapy is not accompanied by a corresponding increase in the predominantly cortical bone of the appendicular skeleton...
		"Osteosclerosis was particularly prominent in axial bones of the spine, pelvis, and ribs...
		The peculiarity of peripheral osteomalacia was its frequent association with axial osteosclerosis...
	www.flouridealert.com /health/bone/density/cortical-trabecular.html (1946 words)

	[No title] (Site not responding. Last check: 2007-11-01)
		It is important to realize that the degree of osteolysis versus the degree of osteosclerosis in a bone lesion has nothing to do with categorizing the lesion as aggressive or nonaggressive.
		Primary tumors of the axial skeleton may be purely osteolytic, osteolytic and osteoblastic, or purely osteoblastic.
		The primary diagnostic considerations for aggressive lesions of the axial skeleton are neoplasia, infection, and trauma.
	cal.vet.upenn.edu /saortho/chapter_73/73mast.htm (3479 words)

	Fluoride's Differential Effect on Bone Density
		"The dramatic increase in the predominantly trabecular bone of the axial skeleton during fluoride therapy is not accompanied by a corresponding increase in the predominantly cortical bone of the appendicular skeleton...
		"Osteosclerosis was particularly prominent in axial bones of the spine, pelvis, and ribs...
		The peculiarity of peripheral osteomalacia was its frequent association with axial osteosclerosis...
	www.fluoridealert.org /health/bone/density/cortical-trabecular.html (2112 words)

	Medcyclopaedia - Osteosclerosis
		Osteosclerosis of the vertebral bodies produces changes at both superior and inferior aspects, leading to an appearance termed the rugger jersey spine.
		Hodgkins disease may be characterized by osteosclerosis alone, osteolysis alone, or both of these together.
		In Paget's disease osteosclerosis may occur in both the active and the inactive stage.
	www.medcyclopaedia.com /library/topics/volume_iii_1/o/osteosclerosis.aspx (765 words)

	Fluorides and Fluoridation - Skeletal Fluorosis
		Fluoride has a positive effect on axial bone density, but the axial bone gain is not matched by similar changes in cortical bone.
		Endemic bent knee is observed primarily in young and adolescent boys and is characterized by: simultaneous osteomalacia; osteosclerosis; and osteoporosis with secondary hyperparathyroidism.
		The fluoride-induced osteosclerosis seems to be reversible, but the long-term significance of fluoride accumulation in the body is not known.
	www.rvi.net /~fluoride/s10.htm (5966 words)

	Fluoridation - Potentially Harmful Fluoride Levels Found in Some Instant Teas
		Radiographs from 1993 and 1998 documented the appearance of marked osteosclerosis and cortical thickening throughout the entire spine (especially the lumbar region) and pelvis during this 5-year period (Figure 1).
		The cortices of the pelvic bones and proximal femur are relatively spared.
		Axial osteosclerosis, exostoses, periostitis, and pelvis ligament calcification are typical radiographic findings.
	www.thenhf.com /skeletal_flourosis_and_instant_tea_study.htm (2681 words)

	osteoporosis osteomalacia axial (Site not responding. Last check: 2007-11-01)
		A combination of osteosclerosis, osteomalacia and osteoporosis net remineralization of bone in both axial and appendicular skeleton due to superior in metabolic bone diseases including osteoporosis, osteomalacia and rickets.
		The axial skeleton is commonly involved, with thickness and composition (ie, the axial skeleton, hip, or whole body turnover versus low-turnover osteoporosis, osteomalacia, secondary hyperparathyroidism, and complicated HEALTH EFFECTS: Fluoride and Osteomalacia.
		Osteoporosis And Exercise Lecture stainability suburbanize osteoporosis osteomalacia axial the mandibular cohesion osteoporosis and exercise
	arthritis.medicalfatcs.com /.../osteoporosis-osteomalacia-axial.html (678 words)

	What are the long-term effects of ingesting fluoride on our bones?
		Osteosclerosis in workers exposed to fluoride (F) and aluminum (Al) (industrial fluorosis) led to the use of F as a treatment to increase bone mass in osteoporosis patients.
		Because the influence of traces of Al on the effects of F on bone formation is heretofore unknown, we have investigated this issue both in vitro and in vivo.
		Thus, osteosclerosis and osteoporosis demonstrated by X-ray should be considered as manifestation of bone fluorosis.
	www.fluoridation.com /bones.htm (15491 words)

	APPENDIX 4: A chronological listing of animal, clinical, and endemic studies of fluoride and bone, with quotations.
		An important point to consider in this regard, is the fact that trabecular bone is the predominant form of bone in the axial skeleton (vertebrae, ribs, cranium) while cortical bone is the predominant form of bone in the appendicular skeleton (limbs).
		The idea was that fluoride-induced osteosclerosis (an increase in bone mass) would serve to counteract osteoporosis, a condition marked by a loss of bone mass.
		Osteosclerosis and interosseous membrane calcification have long been regarded as hallmarks of this disease.
	www.slweb.org /f-bone.html (3412 words)

	Autosomal dominant osteopetrosis - Wheeless' Textbook of Orthopaedics
		[JC:dfy] (294):45-51, 1993 Sep. Autosomal dominant osteopetrosis is radiographically characterized by universal osteosclerosis, primarily involving the axial skeleton, and by symmetrical affections of the long bones without modeling defects.
		Type I is radiographically characterized by pronounced osteosclerosis of the cranial vault, whereas Type II has end-plate thickening of the vertebrae (Rugger-Jersey spine) and endobones in the pelvis.
		Symptoms are progressive with age, and correlated with osteosclerosis.
	www.wheelessonline.com /ortho/autosomal_dominant_osteopetrosis (209 words)

	7.00-Hematological-Adult
		The laboratory findings cited must reflect the values reported on more than one examination over that 3-month period.
		Medically acceptable imaging includes, but is not limited to, x-ray imaging, computerized axial tomography (CAT scan) or magnetic resonance imaging (MRI), with or without contrast material, myelography, and radionuclear bone scans.
		Intractable bone pain with radiologic evidence of osteosclerosis.
	www.ssa.gov /disability/professionals/bluebook/7.00-HemicandLymphatic-Adult.htm (566 words)

	The Turkish Journal of Pediatrics
		This syndrome is characterized by generalized osteosclerosis with craniofacial anomalies and intracranial calcifications.
		Nasal hypoplasia and punctuate calcifications, especially in the axial skeleton, calcaneus and epiphyses of the long bones, are also described in warfarin- induced embryopathy[8].
		Osteosclerosis, hypoplastic nose, and proptosis (Raine syndrome): further delineation.
	tjp.dergisi.org /text.php3?id=221 (1115 words)

	Fluoride and Bone (More)
		Fluoride is well known to cause osteosclerosis, a bone condition marked by an increase of bone mass.
		Increased bone levels of fluoride, osteosclerosis, increased incidence of osteomalacia, and increased plasma levels of fluoride have been reported in these caases.
		Osteosclerosis appeared progressively but was clinically symptomatic in only one patient..
	www.orgsites.com /ny/nyscof2/_pgg3.php3 (9591 words)

	Insulin-like Growth Factor System Abnormalities in Hepatitis C- associated Osteosclerosis . Potential Insights into ...
		Hepatitis C-associated osteosclerosis (HCAO) is a rare disorder characterized by a marked increase in bone mass during adult
		Khosla (1997) Hepatitis C-associated osteosclerosis: an unusual syndrome of acquired osteosclerosis in adults.
		Depczynski (1996) Acquired osteosclerosis associated with intravenous drug use and hepatitis C infection.
	www.jci.org /cgi/content/full/101/10/2165 (5207 words)

	Breaking News - Although fluoride is one of the most potent stimulators of bone formation in-vivo, it is also the least ... (Site not responding. Last check: 2007-11-01)
		Whereas bone mass and architecture in all appendicular and most axial sites is normally controlled by loading history, the new bone formed as a result of artificially stimulated bone remodeling using fluoride is exclusively appositional, with no creation of new trabeculae (Balena, et al.
		It has an "abnormal texture" that is less strong (Lips, 1998), and the loss in trabecular strength due to the adverse influence of fluoride treatment altering the normal control has been calculated (Carter and Beaupre, 1990).
		These large crystals (calcium-fluoride) which are not present in either controls or osteoporotic bone before the fluoride treatment contribute to increased mineral density with no improvement in mechanical properties (ibid, 1994).
	www.johnleemd.net /breaking_news/fluoridation_02.html (4629 words)

	Ernheim-Chester Disease, Nancy Witts, Thu 10:24 AM, 04/22/04
		Histopathology and distribution are similar to Langerhans cell histiocytosis but ECD presents in middle age, cells are S100 negative and lack Birbeck granules, bony lesions are symmetric and sclerotic involving long bones in the region of the metadiaphyses, the symptoms include bone pain, fever, weight loss, exophthalmos, dyspnea, neurologic findings.
		Plain x-rays of involved bones show osteosclerosis with sparing of the epiphyses.
		Patients frequently have cerebellar symptoms including gait ataxia and MRI of the brain shows intra-axial lesions in cerebellum and pons mimicking demyelinating process and often confused with multiple sclerosis.
	www.himaofaz.org /bbs/02/msg/4173.html (243 words)

	[No title] (Site not responding. Last check: 2007-11-01)
		An important point to consider in this regard, is the fact that trabecular bone is the predominant form of bone in the axial skeleton (vertebrae, ribs, cranium) while cortical bone is the predominant form of bone in the appendicular skeleton (arms, legs, hips).
		To help clarify the relevance of skeletal fluorosis studies to fluoride therapy, it is instructive to note the comment made by Riggs (1983) in his comprehensive review of fluoride as a treatment for osteoporosis.
		When fluoride is used therapeutically, therefore, it is obvious that conditions must be carefully chosen so as to maximize the development of osteosclerosis and to minimize the undesirable manifestations of osteoporosis and osteomalacia." - Riggs BL.
	members.lycos.co.uk /thomasdover/papers/fluoride_and_bone.htm (7689 words)

	SAPHO Syndrome of the Temporomandibular Joint Associated with Sudden -- Marsot-Dupuch et al. 20 (5): 902 -- American ...
		A, Axial contrast-enhanced T1-weighted MR image (500/15) reveals focal enhancement of the dura (large arrow) of the temporal bone, spreading into the internal auditory meatus with enhancement of the cochlea (small arrow).
		B, Axial contrast-enhanced T1-weighted MR image of the infratemporal fossa (540/15) (1 cm below A) shows a large soft-tissue mass around the TMJ (arrowhead), involving the lateral pterygoid muscle (arrow).
		C, Axial CT scan of the left temporal bone shows abnormal endosteal sclerosis of the temporal squama (arrow) with subcortical erosions (arrowhead).
	www.ajnr.org /cgi/content/full/20/5/902 (1888 words)

	A boy with bilateral hip pain -- Yamamoto and Fujita 75 (898): 853 -- The British Journal of Radiology
		(b) Anteroposterior radiograph of the right knee reveals a heavily ossified lesion in the distal femur and multiple spotty osteosclerosis in the proximal metaphysis of the tibia (arrows).
		scintigraphic scan showing multiple increased uptake of isotope in the axial and appendicular skeleton.
		or mixed foci in the axial and appendicular skeleton [5].
	bjr.birjournals.org /cgi/content/full/75/898/853 (431 words)

	TOXILIT - Mithal, A.//Trivedi, N.//Gupta, S. K.//Kumar, S.//Gupta, R. K. : Radiological spectrum of endemic fluorosis: ... (Site not responding. Last check: 2007-11-01)
		Osteosclerosis and interosseous membrane calcification have long been regarded as hallmarks of this disease.
		Our study showed in addition a wide variety of radiological patterns: coarse trabecular pattern, axial osteosclerosis with distal osteopenia and diffuse osteopenia.
		Subjects with osteopenic changes had a significantly lower dietary intake of calcium than those groups having normal radiological findings, predominant osteosclerosis or coarse trabecular pattern (p
	www.mib.ch /toxi/lit/p41861.html (144 words)

	Osteomesopyknosis - WrongDiagnosis.com - WrongDiagnosis.com
		Ophanet, a consortium of European partners, currently defines a condition rare when if affects 1 person per 2,000.
		Osteomesopyknosis: Another name for Axial osteosclerosis (or close medical condition association).
		See full list of 6 symptoms of Osteomesopyknosis (Axial osteosclerosis)
	www.wrongdiagnosis.com /medical/osteomesopyknosis_printer.htm (259 words)

	IngentaConnect Bone Densitometry of a Patient with Osteosclerosis (Site not responding. Last check: 2007-11-01)
		Radiographic abnormalities were marked osteosclerosis in the pelvis and vertebral bodies without changes in size.
		The radiologic, densitometric, and biochemical findings in the patient presented herein are compatible with axial osteomalacia.
		Evaluation of total skeleton BMD, and especially skeletal subareas, clearly indicated that the abnormal BMD was restricted to the spine and pelvis whereas the rest of the skeleton was not affected.
	www.ingentaconnect.com /content/hum/jcd/2003/00000006/00000001/art00009 (244 words)

	MIR Teaching file case bs141 (Site not responding. Last check: 2007-11-01)
		Osteomesopyknosis is a rare autosomal dominant condition characterized by osteosclerosis of the axial skeleton.
		Its radiological abnormalities consist of increased density of the vertebral plates, pelvis, and sometimes of the upper part of the femurs.
		It is usually discovered incidentally on radiographic examination, is a mild form of familial osteosclerosis and must be distinguished from osteopetrosis which carries a worse prognosis.
	gamma.wustl.edu /bs141te146.html (268 words)

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