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	eMedicine - Lymphoma, B-Cell : Article by Ajeet Gajra, MD
		Increased incidence of GI lymphomas is observed in patients with celiac sprue and inflammatory bowel disease.
		Two principal cell types are observed in varying proportions: small cells with irregular or cleaved nuclear contours and scant cytoplasm that are referred to as centrocytes (small cleaved cells) and larger cells with open nuclear chromatin, several nucleoli, and modest amounts of cytoplasm that are referred to as centroblasts.
		Mantle cell lymphoma is a tumor of older adults, with a male predominance.
	www.emedicine.com /med/topic1358.htm (10920 words)

	Homo sapiens molecular nosology - Cutaneous lymphomas
		LyP type B is uncommon (< 10%) and is characterized by an epidermotropic infiltrate of small atypical cells with cerebriform nuclei similar to that observed in MF.
		The infiltrates are composed of small lymphocytes, marginal zone B cells (centrocyte-like cells), lymphoplasmacytoid cells, and plasma cells, admixed with small numbers of centroblast- or immunoblast-like cells and many reactive T cells.
		They may be surrounded by a population of small-to medium-sized cells with irregular nuclei, inconspicuous nucleoli, and abundant pale cytoplasm (marginal zone B cells).
	focosi.immunesig.org /pathohomotissueblood_skin.html (9120 words)

	Primary Large B-cell Lymphoma of the Skin
		Although primary cutaneous diffuse large B-cell lymphomas (DLBCLs) except for those of the leg are grouped together with primary cutaneous follicle center cell lymphoma in the European Organization for Research and Treatment of Cancer classification of primary cutaneous lymphomas, they typically lack the usual phenotypic profile of follicular lymphoma.
		Among the cutaneous B lymphomas, B-cell lymphomas of the lower limbs appear as a special subgroup with a prognosis that is possibly worse than that of primary cutaneous B-cell lymphomas located on the trunk, arms or head, with more frequent relapses.
		With a mean follow-up of 31 months, the study confirmed the worse prognosis of lymphomas with a predominance of centroblasts and immunoblasts (3 deaths) compared with lymphomas with a predominance of centrocytes, as well as their higher rate of recurrence (7/11).
	www.thedoctorsdoctor.com /diseases/cbcl_largecell.htm (3909 words)

	Resistance to Fas-Mediated Apoptosis in EBV-Infected B Cell Lymphomas Is Due to Defects in the Proximal Fas Signaling ...
		by the outgrowth of EBV-infected B cell lymphomas in immunosuppressed transplant
		outgrowth of EBV-infected B cells in the context of immunosuppression.
		B inhibition causes spontaneous apoptosis in Epstein-Barr virus-transformed lymphoblastoid cells.
	www.jimmunol.org /cgi/content/full/167/9/5404 (6006 words)

	Theses from Uppsala University : 4567 - Immunoglobulin Gene Analysis in Different B cell Lymphomas
		B cell lymphoma (BCL) comprises a biologically and clinically heterogeneous group of tumors deriving from different stages of B cell development.
		The normal counterpart of mantle cell lymphoma (MCL) has been postulated to be a naïve B cell and in hairy cell leukemia (HCL) it is considered to be a post-germinal centre B cell.
		We conclude that stem cell selection reduced the number of clonal cells linearly, but purging could not totally eliminate the tumor cells from the graft, thus increasing the risk of a relapse.
	publications.uu.se /theses/abstract.xsql?dbid=4567 (554 words)

	TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas
		B-cell lymphoma is a cancer in which the antibody-producing cells (B lymphocytes) multiply uncontrollably and crowd out other blood cells.
		The gene TEL1, which works to slow cell growth and multiplication, is another member of the ETS family and is a known target of mutations in human leukemia.
		It was already known that many human B-cell lymphomas over-express the MYC gene, either because the tumor cells acquire additional copies of this gene or because the cells suffer mutations that affect control over the level of MYC expression.
	www.eurekalert.org /pub_releases/2005-03/sjcr-tgc032105.php (921 words)

	Malignant lymphomas (Site not responding. Last check: 2007-11-05)
		Lymphomas are a group of cancers in which cells of the lymphatic system become abnormal and start to grow uncontrollably.
		The lymphocyte is the main cell of the lymphoid tissue.
		B cell lymphomas are more common among adults, while among children, the incidence of T and B cell lymphomas are almost equal.
	www.healthatoz.com /healthatoz/Atoz/ency/malignant_lymphomas.jsp (2023 words)

	USCAP 2002 Annual Meeting
		It is present in the majority of B cell lymphomas but may occasionally react with T cell lymphomas.
		This is particularly true in the case of immature B cell proliferations such as ALL, and in cases of immunodeficiency related lymphomas.
		Monoclonal antibody L26, an antibody that is restrictive with normal and neoplastic B lymphocytes in routinely fixed and paraffin embedded tissue.
	www.uscap.org /site~/91st/bone10.htm (276 words)

	1995 Scientific Report1995 Scientific Report
		Although the lymphomas often occur in individuals whose immune systems are severely compromised, they can also occur in HIV positive individuals whose immune systems appear to be intact.
		If malignant transformation of B lymphocytes occurs in vitro at a demonstrable frequency, it is also likely to occur in HIV-infected individuals, thereby generating a subset of lymphomas with a viral etiology.
		Thus HIV, in concert with EBV, is oncogenic in B cells.
	www.fccc.edu /research/reports/report95/astrin.html (2184 words)

	Evidence for Replicative Repair of DNA Double-Strand Breaks Leading to Oncogenic Translocation and Gene Amplification ...
		are susceptible to thymic lymphomas (4, 10, 17, 24–27).
		In scenario B it appears that the copying of chromosome 15 to the der(12)b initiates centromeric of the c-myc locus and continues along toward the telomere.
		A non-transgenic mouse model for B-cell lymphoma: in vivo infection of p53-null bone marrow progenitors by a Myc retrovirus is sufficient for tumorigenesis.
	www.jem.org /cgi/content/full/196/4/469 (5735 words)

	The gastric marginal zone B-cell lymphoma of MALT type -- Zucca et al. 96 (2): 410 -- Blood
		lymphoma in a gastric biopsy specimen: prominent lymphoepithelial
		Primary B cell lymphoma of the thyroid and its relationship to Hashimoto's thyroiditis.
		Chromosome 18 breakpoint in t(11;18)(q21;q21) translocation associated with MALT lymphoma is proximal to BCL2 and distal to DCC.
	www.bloodjournal.org /cgi/content/full/96/2/410 (7419 words)

	Dysregulated TCL1 promotes multiple classes of mature B cell lymphoma -- Hoyer et al. 99 (22): 14392 -- Proceedings of ...
		Clonal B cell expansions detected by the PCR analysis of Ig and TCR genomic DNA.
		B and T cells from cell death to the same extent.
		TCL1 overexpression in B cells of transgenic mice (46).
	www.pnas.org /cgi/content/full/99/22/14392 (4751 words)

	BHRF1, the Epstein-Barr virus (EBV) homolog of the BCL-2 (proto-)oncogene, is transcribed in EBV associated B-cell ...
		BHRF1, the Epstein-Barr virus (EBV) homolog of the BCL-2 (proto-)oncogene, is transcribed in EBV associated B-cell lymphomas and in reactive lymphocytes (Meeting abstract).
		Moreover, weak BHRF1 signals were found in 2 T-cell lymphomas where EBER 1/2 expression was detected mainly in sporadic reactive lymphocytes and in one reactive tonsil with sporadic EBER 1/2 positive lymphocytes.
		When BHRF1 transcripts are detected in T-cell lymphomas or in Hodgkin's disease, this is probably due to the presence of reactive EBER 1/2 positive lymphocytes.
	www.aegis.com /aidsline/1996/jun/m9660030.html (491 words)

	[No title] (Site not responding. Last check: 2007-11-05)
		The primary evidence for this is that EBV DNA sequences are often found in B cell malignancies.
		However, not all B cell lymphomas are thought to be caused by EBV.
		B-cell lymphomas in the immunodeficient host can appear in many parts of the body including the mediastinum, pleura, CNS (both brain and spinal cord), and abdominal and mesenteric chain.
	www.stanford.edu /group/virus/herpes/Burkittslymphoma.html (175 words)

	Lymphomas-non B cell
		Large B cells present in peripheral T cell disorders may be due to EBV (in immunodeficient patients) or represent clonal populations that develop into diffuse large B cell lymphoma (
		Lymphomas of small intestine may derive from various subsets of intestinal intraepithelial lymphocytes that are differentially activated by diverse antigenic stimuli
		B cell lymphomas, histiocytic neoplasms, anaplastic carcinoma, melanoma
	www.pathologyoutlines.com /lymphomanonB.html (2352 words)

	Curriculum Vitae
		Resistance to Fas-mediated Apoptosis in EBV-infected B Cell Lymphomas is Due to Defects in the Proximal Fas Signaling Pathway.
		Resistance to Fas and TRAIL-Mediated Apoptosis in EBV+ B Cell Lymphomas from Patients with PTLD.
		Cell Death Pathways In Epstein Barr Virus B Cell Lines From Patients With Post-Transplant Lymphoproliferative Disorder.
	www.stanford.edu /group/TIL/cv/ron.html (1143 words)

	Vincent K. Tsiagbe Ph.D.
		Erianne1 GS; Wajchman2 J; Yauch3 R; Tsiagbe VK; Kim BS; Ponzio NM."B cell lymphomas of C57L/J mice; the role of natural killer cells and T helper cells in lymphoma development and growth".
		Tsiagbe VK; Yoshimoto T; Asakawa J; Cho SY; Meruelo D; Thorbecke GJ."Linkage of superantigen-like stimulation of syngeneic T cells in a mouse model of follicular center B cell lymphoma to transcription of endogenous mammary tumor virus".
		Rabinowitz JL; Tsiagbe VK; Nicknam MH; Thorbecke GJ."Germinal center cells are a major IL-5-responsive B cell population in peripheral lymph nodes engaged in the immune response".
	www.med.nyu.edu /pubs/tsiagv01.html (1476 words)

	NEJM -- Lymphoma-Specific Genetic Aberrations in Microvascular Endothelial Cells in B-Cell Lymphomas
		in 27 B-cell lymphomas for cytogenetic alterations that are
		known to be present in the lymphoma cells.
		From the Institutes of Pathology (B.S., A.C., D.H.) and Medical and Chemical Laboratory Diagnostics (M.E., O.W., I.S.) and the Department of Internal Medicine I, Division of Hematology (U.J.), Center of Excellence in Clinical and Experimental Oncology, Lymphoma Program, Medical University of Vienna, Vienna General Hospital, Vienna.
	content.nejm.org /cgi/content/short/351/3/250?query=prevarrow&ck=nck (743 words)

	Exclusive Detection of the t(11;18)(q21;q21) in Extranodal Marginal Zone B Cell Lymphomas (MZBL) of MALT Type in ...
		FISH in a t(11;18)-positive extranodal lymphoma of MALT-type with YAC DNA probes flanking the breakpoint in 11q21.
		Ott MM, Linke B, Gerhard N, Kneba M, Greiner A, Ott G, Müller-Hermelink HK: Characterization of clonal B-cell populations in gastric MALT lymphomas and chronic gastritis by means of the polymerase chain reaction.
		Ortiz-Hidalgo C, Wright DH: The morphological spectrum of monocytoid B-cell lymphoma and its relationship to lymphomas of mucosa-associated lymphoid tissue.
	ajp.amjpathol.org /cgi/content/full/155/6/1817 (3832 words)

	Weill Cornell researchers identify tumor-suppressor gene important to diffuse large B-cell lymphomas
		Inactivation of a "tumor suppressor" gene could be a major cause of a class of blood cancers called diffuse large B-cell lymphomas, reports a team of researchers at the Weill Medical College of Cornell University.
		They narrowed their search to PRDM1, which plays a key role in the life cycle of B lymphocytes.
		"Normal B cells mature in the bone marrow, then migrate to the lymph nodes," Dr. Tam explains.
	www.news-medical.net /?id=16972 (711 words)

	About Lymphomas (Site not responding. Last check: 2007-11-05)
		Lymphoma is a cancer affecting immune cells called lymphocytes
		For me case discussions among experts (such as case3) show why we should be a little uncomfortable with Let the Patient Decide clinical practice.
		We need to hear the reasoning process of the experts we consult and make use of their educated clinical judgment.
	www.lymphomation.org /aboutNHL.htm (365 words)

	Plasmacellular differentiation in extranodal marginal zone B cell lymphomas of the ocular adnexa: an analysis of the ...
		Plasmacellular differentiation in extranodal marginal zone B cell lymphomas of the ocular adnexa: an analysis of the neoplastic plasma cell phenotype and its prognostic significance in 136 cases -- Coupland et al.
		Plasmacellular differentiation in extranodal marginal zone B cell lymphomas of the ocular adnexa: an analysis of the neoplastic plasma cell phenotype and its prognostic significance in 136 cases
		Keywords: ocular adnexal lymphoma; extranodal marginal zone B cell lymphoma; lymphoma classification; plasmacellular differentiation
	bjo.bmjjournals.com /cgi/content/abstract/89/3/352 (328 words)

	Distinct methylated profiles in Helicobacter pylori dependent and independent gastric MALT lymphomas -- Kaneko et al. ...
		BCL 10 expression in normal and neoplastic lymphoid tissue: nuclear localization in MALT lymphoma.
		Hypermethylation of a 5' CpG island of p16 is a frequent event in non-Hodgkin’s lymphoma.
		Oligoclonality of a composite gastric diffuse large B-cell lymphoma with areas of marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue type.
	gut.bmjjournals.com /cgi/content/full/52/5/641 (3412 words)

	Stem Cell Therapy Treatment and Research - Information page for stem cell therapies treatment
		Stem Cell Therapy Stem Cell Transplants Embryonic Stem Cells Adult Stem Cells Cord Blood Stem Cells Neural Stem Cells Pro and Cons
		Current clinical uses of umbilical, placental, cord blood and other adult stem cells include the successful treatment of the following illnesses, diseases and disorders:
		For more information on how stem cell therapies can help you in recovering from a serious degenerative condition, please contact Jim Cohan and Associates at 818-504-2318.
	www.stemcelltherapies.biz /stemcelltherapies/information (161 words)

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