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| | Untitled (Site not responding. Last check: 2007-10-15) |
 | | Because the phencyclidine analog, BTCP binds to a site on the dopamine (DA) reuptake complex different from that of cocaine (Maurice et al., Neuropharmacology, 30, 591, 1991), it is conceivable that its behavioral effects may differ from those of cocaine. |
 | | To compare further the behavioral effects of BTCP and cocaine, different groups of rats were trained to discriminate either BTCP (5 mg/kg, i.p.) or cocaine (10 mg/kg, i.p.) from saline in a two-lever, FR10 drug discrimination paradigm. |
 | | BTCP engendered dose-related increases in drug-lever (DL) selection in BTCP-trained (ED50=3.3 mg/kg; 95% CL=2.1-5.0) and in cocaine-trained rats (ED50=4.1 mg/kg; 2.9-5.8). |
| www.cpdd.vcu.edu /98abs/kleven.html (283 words) |
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