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Topic: Basal cell layer


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  Basal cell carcinoma - Wikipedia, the free encyclopedia
Basal cell carcinoma (BCC) is the most common skin cancer in humans.
Tumor cells resemble normal basal cells (small, monomorphous) are disposed in palisade at the periphery of the tumor nests, but are spindle-shaped and irregular in the middle.
Basal cell carcinomas develop in the basal cell layer of the skin.
en.wikipedia.org /wiki/Basal_cell_carcinoma   (474 words)

  
 Sloan-Kettering - Basal Cell Carcinoma
Basal cell carcinomas are most often found on the face, neck, hands, or other parts of the body that have been exposed to the sun.
Basal cell carcinomas rarely spread throughout the body and deaths from them are very rare; however, because they often occur on the face, their locally destructive effects can result in serious cosmetic deformity if not diagnosed and treated early.
Basal cell carcinomas are highly curable with both surgical and non-surgical therapy.
www.mskcc.org /mskcc/html/5424.cfm   (374 words)

  
 Dr. Koop - Basal Cell Carcinoma- Health Encyclopedia and Reference
Basal cell carcinoma (BCC) is the most common and least lethal form of all cancers.
The main cause of basal cell carcinoma of the skin is ultraviolet radiation from the sun.
Basal cell carcinomas on the scalp, nose and corners of the nose, are especially troublesome.
www.drkoop.com /encyclopedia/43/199.html   (976 words)

  
 basal cell carcinoma
Basal cell carcinoma is a common, slow-growing tumor that rarely metastasize.
Tumor cells are basal epidermal cells that never mature and lose their nuclei as normal basal cells do.
Tumor cells appear to bud off from the epidermis and grow downward as islands and cords of basophilic cels with hyperchromatic nuclei.
www.brown.edu /Courses/Digital_Path/Skin/basal_cell_carcinoma.htm   (137 words)

  
 Graminex - Cernilton and products containing Flower Pollen Extract - Pathology of Benign Prostatic Hyperplasia (BPH)
The staining of the basal cell layer by the stratum corneum-keratin reaction has been found to be an important differential diagnostic index between typical and atypical hyperplasia and prostatic intraepithelial neoplasia (PIN) of a moderate and severe grade, and between a glandular prostate carcinoma (2,5,28,34).
The basal cell prostatic hyperplasia is characterized by strong stratum corneumkeratin expression (M 903) with a lack of PSA or PAP staining (8,9,10).
The expression of estrogen and progesterone in the stroma neighboring of the prostatic carcinoma is increased (20).
www.graminex.com /clinical_studies/study4.php   (3448 words)

  
 Basal Cell Carcinoma
Basal cell carcinoma accounts for more than 90 percent of all skin cancers in the United States.
Basal cell carcinoma is the most common skin cancer found in Caucasians.
A basal cell carcinoma usually appears as a small, shiny bump or nodule on the skin, and mainly on the areas exposed to the sun, such as the head, neck, arms, hands, and face.
www.saintjosephs.com /healthinfo/adult/skin/basal.asp   (222 words)

  
 Basal Cell Carcinoma
RESULTS: p63 was expressed in the nuclei of epidermal basal and suprabasal cells, in the cells of the germinative hair matrix and the external root sheath of hair follicles, in the basal cells of the sebaceous gland and in the myoepithelial/basal cells of the sweat glands.
Basal cell carcinoma arising from the nipple of the breast is an uncommon malignancy, with only a handful of cases reported in the literature.
Infiltrative basal cell carcinoma is a distinct histologic subtype of basal cell carcinoma (BCC).
www.thedoctorsdoctor.com /diseases/skin_basalcell_ca.htm   (14081 words)

  
 About Basal Cell Carcinoma
Basal cell carcinoma is the most common form of skin cancer, affecting 800,000 Americans each year.
These cancers arise in the basal cells, which are at the bottom of the epidermis (outer skin layer).
Chronic exposure to sunlight is the cause of almost all basal cell carcinomas, which occur most frequently on exposed parts of the body -- the face, ears, neck, scalp, shoulders, and back.
www.skincancer.org /basal/index.php   (792 words)

  
 Vertical Movement of Epithelial Basal Cells toward the Corneal Surface during Use of Extended-Wear Contact Lenses -- ...
cell in the corneal epithelium (basal or suprabasal) was determined.
decreases in corneal epithelial basal cell proliferation and
The percentages of BrdU-labeled cells in the basal cell layer of the contralateral control eyes in the low- and medium-Dk/t RGP lens–wearing rabbits were identical with the control eyes of rabbits wearing no contact lens.
www.iovs.org /cgi/content/full/44/3/1056   (4932 words)

  
 Targeted activation of {beta}-catenin signaling in basal mammary epithelial cells affects mammary development and leads ...
the basal cell layer of mouse mammary epithelium.
progenitor cell population in the mammary epithelium and its
to the basal layer of the mammary epithelium.
dev.biologists.org /cgi/content/full/132/2/267   (6016 words)

  
 Skin cancer - basal cell and squamous cell carcinoma
Basal cell carcinoma is a cancer that begins in the deep basal cell layer of the epidermis (the outer layer of the skin).
Basal cell carcinoma is not one of the most dangerous cancers but it must still be treated to avoid it spreading.
It is not as common as basal cell carcinoma and is typically found in places exposed to sunlight, like the face or neck.
www.netdoctor.co.uk /diseases/facts/skincancernonmelanoma.htm   (684 words)

  
 Skin cancer article - Skin cancer medicine dermatology cancer squamous cell carcinoma basal cell - What-Means.com   (Site not responding. Last check: 2007-10-20)
The most common types are squamous cell carcinoma and basal cell carcinoma, while the most dangerous is malignant melanoma.
Skin cancer is an increasingly common condition, attributed in part to the degradation of the ozone layer and the consequently increased levels of ultraviolet radiation, and also due to the recent popularity of sun tanning (sun bathing), against which no level of sun screens offer any decisive protection.
Minor surface skin cancers are readily treatable by simple surgery, but if the cancer is allowed to grow then it will penetrate through the layers of skin and affect the lymphatic system.
www.what-means.com /encyclopedia/Skin_cancer   (171 words)

  
 Confocal microscopic study of rabbit and human corneal epithelia using two objectives with different
The outermost layer of the human cornea, the corneal epithelium, consists of 5-6 layers of 3 different types of epithelial cells: 2-3 layers of superficial cells, 2-3 layers of intermediate cells (wing cells), and a single layer of collunar basal cells
The basal layer cells had bright outlines and their contents were dark, unlike the confocal microscope appearance of corneal endothelial cells, in which the cell outlines were dark and contents were bright.
The basal and the intermediate cell layers of the rabbit corneas were visible only with the high NA objective.
www.abonet.com.br /abo/abo62604.htm   (3147 words)

  
 Basal cell carcinoma - free-definition   (Site not responding. Last check: 2007-10-20)
It develops in the basal cell layer of the skin and can be very destructive and disfiguring.
There are different types of basal cell carcinomas which can look very different, but most commonly the carcinoma begins as a shiny papule that shows a pearly translucent border after months or even years with engorged superficial vessels.
Basel cell carcinoma rarely metastasizes, but invades healthy tissue in the proximity.
www.free-definition.com /Basal-cell-carcinoma.html   (174 words)

  
 patients
Basal cell carcinoma is the most common skin cancer in humans.
Melanoma and nonmelanoma (basal and squamous cell carcinoma) skin cancer are now the most common type of cancer in the Caucasian population and the incidence of skin cancer has reached epidemic proportions.
Although basal cell carcinoma may appear on apparently healthy skin it usually is related to damaged or injured skin.
skincancer.dermis.net /content/e04typesof/e148/e149/index_eng.html   (2290 words)

  
 Epidermis - skin care information
It is made up of five layers: the basal cell layer, the squamous cell layer, the stratum granulosum, the stratum lucidum, and the stra­tum corneum.
Above the basal cell layer is the squamous cell layer, also called the stratum spinosum or “spiny layer” because the cells are held to­gether with spiny projections.
The squamous cell layer is the thickest layer of the epidermis.
www.essentialdayspa.com /epidermis-c_17.htm   (615 words)

  
 Morphometric analysis of basal cell layer in oral premalignant white lesions and squamous cell carcinoma -- Shabana et ...
Morphometric analysis of basal cell layer in oral premalignant white lesions and squamous cell carcinoma -- Shabana et al.
Morphometric analysis of basal cell layer in oral premalignant white lesions and squamous cell carcinoma
in squamous cell carcinoma was twice as large as in normal mucosa.
jcp.bmjjournals.com /cgi/content/abstract/40/4/454   (249 words)

  
 CONFOCAL IN VIVO MICROSCOPY OF THE NORMAL CENTRAL CORNEAL EPITHELIUM   (Site not responding. Last check: 2007-10-20)
Results: Images of the basal cell layer were obtained in 49 cases.
In one case the basal layer was not visible.
In 18 cases a homogenous low to medium reflective cell layer image, seperated by medium reflective cell boarders, with no or dark core region in 12 cases, or medium to high reflective core in 6 cases was found.
www.dog.org /1998/e-abstract98/509.html   (318 words)

  
 Study 4: Pathology of Benign Prostatic Hyperplasia (BPH)   (Site not responding. Last check: 2007-10-20)
Labeling of the basal cell layer by the stratum corneum-keratin reaction (PAP method; x 63).
Expression of prostatic specific antigen (PSA) in the secretory cells of the hyperplastic prostate gland.
Patchy staining of the basal cells in atypical hyperplasia with stratum corneumkeratin (PAP; x 160) (31).
www.cernitinamerica.com /study4.html   (3406 words)

  
 Medical Information -- Prostatic Intraepithelial Neoplasia (PIN)-- bostwicklaboratories.com
PIN is associated with progressive abnormalities of phenotype and genotype that are similar to cancer rather than normal prostatic epithelium, indicating impairment of cell differentiation with advancing stages of prostatic carcinogenesis.
(1,2) PIN coexists with cancer in more than 85% of cases (3, 8) but retains an intact or fragmented basal cell layer, unlike cancer which lacks a basal cell layer.(5) The clinical importance of recognizing PIN is based on its strong association with prostatic carcinoma.
PIN spreads through prostatic ducts in multiple different patterns, similar to prostatic carcinoma.(6,15-16) In the first pattern, neoplastic cells replace the normal luminal secretory epithelium, with preservation of the basal cell layer and basement membrane.
www.bostwicklaboratories.com /edresour/pin/article.htm   (935 words)

  
 Basal Cell Carcinoma   (Site not responding. Last check: 2007-10-20)
A type of skin cancer that arises from the basal cells, small round cells found in the lower part (or base) of the epidermis, the outer layer of the skin.
It develops in the basal cell layer of the skin and can, if neglected, be very destructive and locally disfiguring.
Because basal cell carcinoma rarely spreads, a biopsy often is the only test needed to determine the stage.
www.cubadermatologysymposium.com /cbasal.htm   (244 words)

  
 Absence of Caveolin-1 Sensitizes Mouse Skin to Carcinogen-Induced Epidermal Hyperplasia and Tumor Formation -- Capozza ...
Note that in Cav-1 null mice all of the layers of the epidermis, especially the basal, granular, and cornified layers are hyperplastic or thickened.
Note that in Cav-1 null mice both the suprabasal cell layer (keratin-10 immunostaining, A) and the basal cell layer (keratin-14 immunostaining, B) are increased in thickness and appear hypercellular.
In wild-type animals, mainly the proliferative basal cell layer is immunostained for cyclin D1; in contrast, in Cav-1 null animals, both the basal cell layer and the suprabasal layers are heavily immunostained.
ajp.amjpathol.org /cgi/content/full/162/6/2029   (5767 words)

  
 Basal cell carcinoma of the skin Health Guide - Health Guides Online
A malignant tumour of the skin thought to arise from epidermal basal cells.
It resembles the undifferentiated cells of the basal layer of the epidermis.
When these cancers are detected and treated early the cure rate and prognosis is very high.
www.healthguidesonline.com /Basal_cell_carcinoma_of_the_skin.html   (792 words)

  
 Stanford Hospital And Clinics - Stanford University Medical Center - Basal Cell Carcinoma   (Site not responding. Last check: 2007-10-20)
Basal cell cancer, sometimes called non-melanoma skin cancer, usually appears as a small, flesh-colored bump or nodule on the head, neck, or hands.
Occasionally, these nodules appear on the trunk of the body. Basal cell carcinoma accounts for more than 90 percent of all skin cancers in the United States.
People who have this cancer frequently have light hair (red or blond), green or blue eyes, and fair complexion, with tendency to sunburn.
www.stanfordhospital.com /healthLib/greystone/skin/basal.html   (261 words)

  
 Basal cell layer - Wikipedia, the free encyclopedia
The basal cell layer is also called the Stratum Germinativum or Stratum Basale and is the innermost layer of the epidermis.
Cells are produced here in the germinal layer and forms the prickle cells in the above layer (the Stratum Spinosum).
This page was last modified 01:21, 31 July 2005.
en.wikipedia.org /wiki/Basal_cell_layer   (84 words)

  
 Nevoid Basal Cell Carcinoma Syndrome
It is possible that the main title of the report Nevoid Basal Cell Carcinoma Syndrome is not the name you expected.
Nevoid basal cell carcinoma syndrome (NBCCS), also known as Gorlin or Gorlin-Goltz syndrome, is an inherited disorder characterized by a tendency to develop multiple cancerous cysts, lesions (nevi) of the skin and lining of the mouth, and other developmental and systemic defects.
The lesions (nevus, nevi) are usually found in the outer layer of the skin (epidermis) or in the mucous membranes of the mouth.
www.bchealthguide.org /kbase/nord/nord681.htm   (433 words)

  
 Feline Basal Cell Carcinoma   (Site not responding. Last check: 2007-10-20)
A low-grade malignant proliferation of epidermal cells that recapitulates the basal cell layer of the normal epidermis or the adnexa.
There are histologic variants of basal cell carcinoma.
Architecture is that of a solid basal cell carcinoma
cal.vet.upenn.edu /derm2/epi/fbcc.html   (141 words)

  
 Arch Dermatol -- Abstract: Clinical significance of basal cell layer antibodies, October 1977, Bystryn 113 (10): 1380
Arch Dermatol -- Abstract: Clinical significance of basal cell layer antibodies, October 1977, Bystryn 113 (10): 1380
Circulating antibodies in humans were found to antigens present only in the
basal cell layer of stratified squamous epidermis by the immunofluorescence
archderm.ama-assn.org /cgi/content/abstract/113/10/1380   (69 words)

  
 Immunohistochemical Expression of p-Class Glutathione S-Transferase in the Basal Cell Layer of Benign Prostate Tissue ...   (Site not responding. Last check: 2007-10-20)
The relationship of VEGF expression to chromogranin A positive (e.g., neuroendocrine) cells was investigated.
Significant levels of VEGF are present in prostate cancer and in a population of PIN lesions, the expression being highest in association with NE cells and correlated with an altered pattern of vascularization.
The VEGF expression is downregulated by hormonal manipulation, except in the population of NE cells.
ejpath.amu.edu.pl /ejp8-1/021-06.htm   (283 words)

  
 Basal Cell Carcinoma   (Site not responding. Last check: 2007-10-20)
Common, locally destructive, nonmetastasizing malignancy of the skin composed of medullary pattens of basaloid cells.
round to ovoid solid nests of tumor cells showing multiple cystic areas
cells are uniform in size and polygonal in shape with prominent nuclei and scant cytoplasm
www.marquette.edu /dentistry/oralpath/lesions/bcc/bcc.htm   (222 words)

  
 Skin Cancer: symptoms, detection, prevention, and treatment options
What Is Basal Cell Cancer What Causes Basal Cell Cancer Basal Cell Cancer Treatment
From skin cancer symptoms to currently available treatments for skin cancer, Skin Cancer Guide offers comprehensive information to those looking for answers to their questions about actinic keratosis, basal cell cancer, superficial basal cell cancer, squamous cell cancer, and melanoma.
Basal cell cancer, squamous cell cancer, melanoma, early signs of skin cancer.
www.skincancerguide.ca /tf/content.asp?z=821   (382 words)

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