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Topic: Basal lamina


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In the News (Mon 17 Jun 19)

  
  CiteULike: Astrocytes secrete basal lamina after hemisection of rat spinal cord.
Basal lamina is reconstructed over the lesioned surface of the spinal cord.
Ultrastructurally (3 days), basal lamina was polymerizing as small projections on the surface of astrocytic membranes facing the lesion, endothelia or pia.
By 5 days the basal lamina was a single membrane, folded multiple sheets or in swirls.
www.citeulike.org /user/cite0000/article/803313   (460 words)

  
  Dorlands Medical Dictionary
In the renal glomeruli and the pulmonary alveoli, it is bounded by the lamina rara externa and the lamina rara interna.
It consists of nine laminae (I–IX) that extend throughout the cord, roughly paralleling the dorsal and ventral columns of the gray substance, and a tenth region (lamina X) that surrounds the central canal and consists of the dorsal and ventral commissures and the central gelatinous substance.
(lam”ĭ-not´ə-me) [lamina + -tomy] division of the lamina of a vertebra.
www.mercksource.com /pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_l_02zPzhtm   (3781 words)

  
 BBB association with pericytes, astrocytes and basal lamina   (Site not responding. Last check: )
The basal lamina surrounds the endothelial cells and pericytes; the region between which is known as the Virchow-Robin space.
Between brain capillaries, astrocytes, and pericytes is the basal lamina, which consists of laminin, fibronectin, tenascin, collagens, and proteoglycan (Heimark, 1993).
Cell adhesion to the basal lamina involves the integrins (Hynes, 1992).
users.ahsc.arizona.edu /davis/bbbpericyte.htm   (681 words)

  
 [No title]
The basal lamina is a sheetlike structure, usually composed of type IV collagen, proteoglycan, and laminin, a glycoprotein that aids in binding cells to the basal lamina.
Basal lamina components are contributed by the epithelial cells, the underlying connective tissue cells, and (in some locations) muscle, adipose, and Schwann cells.
Basal laminae accompanied by reticular laminae are often thick enough to be seen with the light microscope as PAS- positive layers and are sometimes termed basement membranes, b.
www.loyno.edu /~chood/histnotesepith.html   (3262 words)

  
 Epithelium
In some cases the basal laminae are greatly thickened (as in the glomeruli and filtration system of the kidneys).
The basal laminae, as seen by transmission electron microscopy, are seen to be formed from an electron-dense layer (50-80 nm thick) composed of non-fibrous type IV collagen and the proteoglycan, heparan sulfate, surrounded on both sides by a less-dense layer containing the glycoprotein, laminin.
Basal laminae are not exclusive features of epithelia, but are also found associated with endothelia and some other cell types.
www.technion.ac.il /~mdcourse/274203/lect2.html   (2682 words)

  
 Basal lamina disorganisation of the acini and ducts of labial salivary glands from patients with Sjogren's syndrome: ...
Basal lamina disorganisation of the acini and ducts of labial salivary glands from patients with Sjogren's syndrome: association with mononuclear cell infiltration.
OBJECTIVE: To study the expression of laminin and type IV collagen as biomarkers of the organisation of the basal lamina of acini and ducts in labial salivary glands from patients with Sjögren's syndrome, and to relate this organisation to inflammatory cell invasion of acini and ducts.
A remarkable characteristic was the disorganisation of the basal lamina in the labial salivary glands in Sjögren's syndrome.
rheumatoidarthritis.researchtoday.net /archive/3/1/1194.htm   (367 words)

  
 Canolfan Edward Llwyd
The basal lamina is also able to determine cell polarity, influence cell metabolism, organise the proteins in adjacent plasma membranes, promote cell survival, proliferation or differentiation, and serve as specific highways for cell migration.
The term basement membrane is often used to describe the basal lamina and this layer of collagen fibrils, although it isn’t strictly a membrane.
The basal lamina is structured differently in different tissues, the lamina found on one side of endothelial cells forms a filter for regulating passage of proteins and molecules from the blood into tissues.
www.aber.ac.uk /gwydd-cym/cellbiol/ECM/basallamina.htm   (477 words)

  
 Basal lamina - Wikipedia, the free encyclopedia
The basal lamina is a component of the basement membrane that separates epithelium from the underlying connective tissue.
The exception is when two epithelial layers abut one another as in the alveoli of the lungs and glomeruli of the kidneys, in which the basal lamina of one epithelial layer fuses with that of the other.
The combination of the basal lamina and reticular lamina (or of two basal laminae) is called the basement membrane, a light microscopy term that predated the invention of the electron microscope.
en.wikipedia.org /wiki/Basal_lamina   (386 words)

  
 Microfabrication of an analog of the basal lamina: biocompatible membranes with complex topographies -- PINS et al. 14 ...
Microfabrication of an analog of the basal lamina: biocompatible membranes with complex topographies -- PINS et al.
Microfabrication of an analog of the basal lamina: biocompatible membranes with complex topographies
In the glomerulus of the kidney, the basal lamina
www.fasebj.org /cgi/content/full/14/3/593   (4957 words)

  
 Epithelia and Tissue Lab
However, because the basal lamina is very thin, it will appear as a very thin line at the base of the tubules.
The basal layer of epithelial cells is sparse and compressed down at the basal lamina.
Lamina propria contains a resident population of different cell types including fibroblasts, adipose cells and mast cells that you may be able to identify in your slides.
www.fsu.edu /~histo/two~1.htm   (2932 words)

  
 LLU - EPITHELIUM
This fundamental tissue is characterized by its lack of vessels, little intercellular material, and by the presence of a basement membrane anchoring it to the underlying connective tissue stroma and separating it from its nutrient vessels.
Desmosomes, between cells, and hemidesmosomes or attachment plaques, at basal lamina, are localized spots where there is an accumulation of fibrillar and granular cementing material between cells or between the cell and the basal lamina.
Contractile myoepithelial cells are usually found between the secretory cells and the basal lamina.
www.llu.edu /llu/medicine/anatomy/glossary/syllabus/Epithelia.htm   (1028 words)

  
 basement membrane Dr.Jastrow's electron microscopic atlas
In short the basement membrane is comprised of the 3-layered basal lamina and the lamina fibroreticularis.
A Lamina fibroreticularis is missing at these locations: a.) basement membrane of glomeruli in kidney located between podocyte processes and endothelial cells of the glomerular capillaries; b.) in the capsule of the lens of the eye and c.) beneath transverse tululi (T-Tubuli) of heart muscle cells.
In the area of the blood air barrier between alveolar epithelial cells type 1 and endothelial cells of the capillaries in ling alveols the basal laminae of both cells join to a common relatively thin lamina to facilitate diffusion of gases.
www.uni-mainz.de /FB/Medizin/Anatomie/workshop/EM/EMBasalmembranE.html   (781 words)

  
 Epithelia Study Guide
The basal surfaces faces the basal lamina and the blood vessels.
In addition, the next region is actually a capillary and what we are seeing is the basal lamina of the kidney epithelial and the capillary endothelial cells.
In those basal lamina attached to epithelia sitting on connective tissue, there are additional types of anchoring fibers.
cellbio.utmb.edu /microanatomy/epithelia/epith_lec.htm   (1779 words)

  
 EXTRACELLULAR MATRIX (ECM)
Type IV collagen forms a two-dimensional reticulum and is a major component of the basal lamina.
The basal lamina is often refered to as the type IV matrix.
Each of the components of the basal lamina is synthesized by the cells that rest upon it.
web.indstate.edu /thcme/mwking/extracellularmatrix.html   (820 words)

  
 BioMed Central | Abstract | Aging is associated with increased collagen type IV accumulation in the basal lamina of ...
Aging is associated with increased collagen type IV accumulation in the basal lamina of human cerebral microvessels
The goal of this study was to evaluate age and hypertension related changes of the basal lamina in cerebral microvessels of individuals, who died from non-cerebral causes.
Basal lamina changes of the cerebral microvessels were determined in the putamen using antibodies against collagen type IV and by quantitative analysis of vessel number, total stained area of collagen, thickness of the vessel wall and lumen, and relative staining intensity using immunofluorescence.
www.biomedcentral.com /1471-2202/5/37/abstract   (328 words)

  
 Laminin and the malaria parasite's journey through the mosquito midgut -- Arrighi et al. 208 (13): 2497 -- Journal of ...
Thus, binding of the ookinete to the basal lamina is a condition
that the basal lamina and its integrity are vital for parasite development.
Reinhardt, C. and Hecker, H. Structure and function of the basal lamina and of the cell junctions in the midgut epithelium (stomach) of female Aedes aegypti L. (Insecta, Diptera).
jeb.biologists.org /cgi/content/full/208/13/2497   (3775 words)

  
 Steve's place - Extracellular Matrix
The basal lamina (BL) is a specialised ECM found underlying epithelial cells: it coats muscle and fat cells, forms the glomerular filter in the kidney, and wraps the myelin sheath formed from Schwann cells on nerve axons.
A specialised basal lamina forms the glomerular basement membrane, which is the filter of the kidney, and confers most of the filter's specificity: note the gaps between the epithelial and endothelial cells.
Laminin is the pioneer of the basal lamina.
www.steve.gb.com /science/extracellular_matrix.html   (2897 words)

  
 Basal lamina disorganisation of the acini and ducts of labial salivary glands from patients with Sjogren's syndrome: ...
Basal lamina disorganisation of the acini and ducts of labial salivary glands from patients with Sjogren's syndrome: association with mononuclear cell infiltration -- Molina et al.
Basal lamina disorganisation of the acini and ducts of labial salivary glands from patients with Sjögren’s syndrome: association with mononuclear cell infiltration
characteristic was the disorganisation of the basal lamina in
ard.bmjjournals.com /cgi/content/abstract/65/2/178   (309 words)

  
 Int. J. Dev. Biol. - Cellular origin of the basement membrane in embryonic chicken/quail chimeras.   (Site not responding. Last check: )
ABSTRACT The cellular origin of the components of the basal lamina of an epithelium, the chicken epiblast, has been investigated in a model system resulting from the transplantation of metabolically labeled quail hypoblast (an epithelium without basal lamina), associated or not with individual mesoblast cells, into an unlabeled chicken blastoderm deprived of its own hypoblast.
The ability to discriminate chicken from quail cells after nuclear staining, combined with autoradiographic labeling of the basal lamina components, made it possible to determine the origin of the cells and labeled compounds in tissue sections of the chimeras.
It is concluded that the basal lamina of the epiblast has a dual epithelial origin, resulting from the interaction of epiblast-derived materials and non-collagenous glycoproteins synthesized by the hypoblast.
www.ijdb.ehu.es /web/paper.php?doi=8398681   (318 words)

  
 Epithelia
The basement membrane, a structure seen with the light microscope, has been subdivided into a basal lamina (thought to be produced by the epithelium) and a reticular lamina (produced by connective tissue cells).
Inspection of the epithelial layer at low-power indicates that the basal surface of the epithelium is indented by connective tissue papillae.
The plasma membrane nearest the basement membrane is the basal membrane; the apical membrane lines the free surface, and the lateral membrane is between adjacent cells.
ect.downstate.edu /courseware/histomanual/epithelia.html   (1472 words)

  
 Highbeam Encyclopedia - Search Results for lamina
basal lamina One of two layers (the other is the reticular lamina) that form the basement membrane.
Lamina Ceramics Receives $12-million in Venture Funding; Bonded Ceramic-on-Metal Promises to Become Enabling Technology for Next Generation RF and Optical Communications Components and Packaging.
Lamina Ceramics Sets Another World Record With Brightest-Ever LED Array; Company unveils 28,000-lumen solid state white light engine; shatters record it set in October.
www.encyclopedia.com /SearchResults.aspx?Q=lamina   (527 words)

  
 [No title]
Unfortunately, no studies on alterations of the different basal laminal components in diabetic peripheral nerves have been detailed enough to confirm whether there is an alteration in the proportions of the various components.
Morphometric and morphological studies on human nerves suggest that the factors causing thickening of vascular basal lamina differ from those producing widened basal lamina in the perineurium.85 These studies suggested that the alterations in perineurial basal lamina were more characteristic of diabetic neuropathy than thickening of the basal laminal zone around endoneurial capillaries.
Basal laminal changes of both perineurial cells and blood vessels differ from the Schwann cell basal laminal changes, where the abnormality is its abnormal shape and persistence during regeneration; on undamaged fibres it appears to be normal.
www.lycos.com /info/diabetic--figs.html?page=2   (530 words)

  
 Basal lamina of ovarian follicle regulates an inward Cl- current in differentiated granulosa cells -- Qin et al. 282 ...
Basal lamina was isolated as previously described (4, 7).
Differentiated chicken granulosa cells were incubated on plastic or intact basal lamina in serum-free medium 199 for 24 h in the absence and presence of 5 µg/ml cycloheximide.
Basal lamina of avian ovarian follicle: influence on morphology of granulosa cells in-vitro.
ajpcell.physiology.org /cgi/content/full/282/1/C34   (7190 words)

  
 Basal lamina disorganisation of the acini and ducts of labial salivary glands from patients with Sjogren's syndrome: ...   (Site not responding. Last check: )
Basal lamina disorganisation of the acini and ducts of labial salivary glands from patients with Sjogren's syndrome: association with mononuclear cell infiltration -- Molina et al.
characteristic was the disorganisation of the basal lamina in
The disorganisation of the basal lamina of acini and ducts of
www.arabmedmag.com /issue-15-03-2006/rheumatology/main01.htm   (3559 words)

  
 EPITHELIA
In stratified epithelia, the basal layer of cells rests on the basal lamina, but subsequent layers do not, and are simply stacked on top of the basal layer.
An epithelium always rests on a basal lamina, and this basal lamina is the interface between the epithelium and underlying connective tissue.
They rest on a basal lamina, and their secretion is polarized towards the lumen at their apical surface.
medocs.ucdavis.edu /cha/402/labsyl/01/02.htm   (2408 words)

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