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Topic: Benzopyrene

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Aromatic hydrocarbon

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	Benzopyrene - Wikipedia, the free encyclopedia
		Benzopyrene is a product of incomplete combustion at temperatures between 300 and 600°C.
		A chemical found in tobacco smoking, benzopyrene, was shown to cause genetic damage in lung cells that is identical to the damage observed in the DNA of most malignant lung tumours.
		A 2001 National Cancer Institute study found levels of benzopyrene to be significantly higher in foods that were cooked well-done on the barbecue, particularly steaks, chicken with skin, and hamburgers.
	en.wikipedia.org /wiki/Benzopyrene (314 words)

	Newhouse A1
		Well-done barbecued hamburgers are among meats found to contain benzopyrene, a carcinogen carried in smoke.
		The smoke contains benzopyrene, a potent carcinogen in animals, particularly in the gastrointestinal tract.
		A 2001 National Cancer Institute study found levels of benzopyrene, also known as benzo(a)pyrene, to be significantly higher in foods cooked well-done on the barbecue, particularly steaks, chicken with skin, and hamburger.
	www.newhousenews.com /archive/seeman052004.html (879 words)

	JournalNow Special Report : RJR R J Reynolds Tobacco - Lost Empire
		Benzopyrene and other polycyclic hydrocarbons were first, followed by aza-arenes, phenols, aldehyde, ketone, nitrosamine, polonium-210.
		Benzopyrene is formed whenever anything organic is burned, and Rodgman confirmed its existence in cigarette smoke in 1956.
		RJR researchers found that solanesol, a long-chain hydrocarbon that was the primary precursor of benzopyrene, could be greatly reduced by treating the tobacco with the solvent hexane.
	extras.journalnow.com /lostempire/tob20a.htm (1780 words)

	JournalNow Special Report : RJR R J Reynolds Tobacco - Lost Empire
		Scientists by then knew that benzopyrene, among a class of compounds called polycyclic hydrocarbons, was present after organic material was burned.
		Its propensity to trigger cancer had been known since 1910 when benzopyrene was identified as the cause of the scrotum cancer that chimney sweeps in England had developed.
		Benzopyrene is still in cigarette smoke in minute quantities, though Reynolds and other companies tried to remove it.
	extras.journalnow.com /lostempire/tob5c.htm (1902 words)

	Benzopyrene - TheBestLinks.com - Animal, Carcinogen, Meat, Organic compound, ...
		Benzopyrene - TheBestLinks.com - Animal, Carcinogen, Meat, Organic compound,...
		Benzopyrene, Animal, Carcinogen, Meat, Organic compound, Plant, Smoke, Tobacco...
		Benzopyrene is a carcinogenic organic compound which is produced by charring animal or plant matter.
	www.thebestlinks.com /Benzopyrene.html (97 words)

	Guardian Unlimited \| Special reports \| Close encounters (Site not responding. Last check: 2007-10-13)
		The yellow, crystalline chemical is found in coal tar and cigarette smoke and is produced when organic matter is inefficiently burnt.
		Benzopyrene is one of a group of polycyclic aromatic hydrocarbons (PAHs) that have been shown to cause cancer in animals.
		Indeed, benzopyrene is sometimes used in laboratory experiments to induce a range of cancers in mice.
	www.guardian.co.uk /chemicalworld/story/0,14534,1219603,00.html (859 words)

	Why do carcinogens like nicotine cause cancer?
		DNA damaged by Benzopyrene-diol-epoxide Benzopyrene is a chemical found in cigarette smoke.
		Benzopyrene is converted to Benzopyrene-diol-epoxide in the body, which can randomly insert itself into the grooves of DNA.
		Once bound in the groove, DNA is not able to be replicated or transcribed effectively.
	www.edinformatics.com /interactive_molecules/dna.htm (337 words)

	Top-Rated Pollutants in Russian Federation
		That exposure group is closely followed, in terms of size, by those in contact with polycyclic aromatic hydrocarbons (benzopyrene) (14 million), and people exposed to phenol constitute the third-largest group (13 million).
		Benzopyrene content is monitored in 170 Russian cities.
		It would be unfair not to mention that the Soviet Union was the first nation in the world to raise the problem to the high level it did.
	www.chem.unep.ch /pops/POPs_Inc/proceedings/stpetbrg/kurlyand.htm (1292 words)

	K-State researcher links cigarette smoke, vitamin A deficiency and emphysema
		In his most recent research, Baybutt exposed a group of rats to cigarette smoke and found that those rats became vitamin A deficient.
		Benzopyrene, a common carcinogen found in cigarettes, is the link to the deficiency, Baybutt said.
		When fed to rats, benzopyrene induces vitamin A deficiency.
	www.eurekalert.org /pub_releases/2004-07/ksu-krl072604.php (393 words)

	Smoked meats: food makers to watch carcinogen PAH levels
		From 1 April new rules set maximum levels for benzopyrene in fish and meat products will be 5 micrograms/kg, in oils and fats 2 micrograms and in children's foods 1 microgram/kg.
		Increasingly pinpointed by consumer organisations as a food safety issue in the food chain, Polycyclic Aromatic Hydrocarbons (PAH), of which benzopyrene figures prominently, are a group of over 100 different chemicals that are formed during the incomplete burning of coal and oil, or other organic substances like tobacco or charbroiled meat.
		The new barrier levels against PAH contamination, in particular benzopyrene, firm up temporary measures set up while the Commission accumulated more data on this potential contamination problem highlighted by stakeholder groups.
	www.thepigsite.com /LatestNews?AREA=LatestNews&Display=9063 (419 words)

	Letter to Editor (Site not responding. Last check: 2007-10-13)
		Benzopyrene, a deadly toxin that is highly volatile, exists at six times "acceptable limits" at that site.
		Aside of the health and ecological concerns of building shopping shelves atop benzopyrene are the potential legal and financial concerns.
		The announcement by the environmenta department that there are "no proven adverse affects" from selling food a few feet from tonnes of benzopyrene soil and other toxins is particularly disturbing.
	www.sierraclub.ca /atlantic/cbgroup/old_site/lte99420.html (628 words)

	NEW FUNCTIONS OF P53 GENE: REGULATORY AND HYPERSENSITIVE SITES IN EXONS OF MUTANT P53 MRNA FORMS
		The models of aflatoxin B1 and benzopyrene interactions with the critical codons 249/248 were created: these codons were shown to be located in the looped regions.
		The invariant DNA/RNA secondary structures for exons 5-8 of p53 gene were calculated basing on the epidemiological data on the mutations in p53 and the revealed "hotspots"---targets of forming the mutagen and carcinogen adducts with DNA.
		The models of aflatoxin B1 and benzopyrene with the critical codons 249/248 were created: these codons were shown to be located in the looped regions (Figs.
	www.bionet.nsc.ru /bgrs/thesis/45 (2066 words)

	The Black Informant » Blog Archive » Weekend Health Clinic: Cooking on the Grill
		During broiling, fat from the meat drips onto the charcoal, producing benzopyrene that distills back up onto the meat.
		Benzopyrene is one of the main cancer-producing agents found in tobacco smoke.
		In Iceland, where large amounts of smoked fish containing benzopyrene are consumed, there are large numbers of patients with cancer of the stomach and intestinal tract.
	blackinformant.com /index.php?p=277 (561 words)

	SIGHTINGS
		He said NATO air power's destroying of Yugoslavia's refineries and setting them to fire are associated with the release of large amounts of hydrocarbons, the most dangerous of which is benzopyrene.
		The US' using the shells with depleted uranium in operation Desert Storm in Iraq has left 20-25 percent of the American and British personnel involved in it with diseases and abnormalities at the genetic level, Alekseyev said.
		NATO's raids are contaminating Yugoslavia and adjacent European states with dioxins, benzopyrene and uranium, he said.
	www.rense.com /politics2/diox.htm (480 words)

	Portland NORML News - Saturday, September 19, 1998
		Many foods have more benzopyrene and other polycyclic aromatic hydrocarbons in quantities greater than one finds in the stale Mexican marijuana tested by Hoffman and found to contain 31 ng of benzopyrene per joint in his 1975 report.
		The most relevant animal study which specifically used inhalation of benzopyrene, found over 1,500 joints per day worth of benzopyrene to have no negative effect on the little quarter pound hamsters used in the experiment.
		Please let me know if you are interested in my complete 9 page report on benzopyrene, full of very reputable references, so that you can see how outrageous it is to claim that marijuana is very carcinogenic - while the evidence points to the fact that it fights cancer rather efficiently.
	www.pdxnorml.org /980919.html (6373 words)

	Lung Cancer (Site not responding. Last check: 2007-10-13)
		A breakthrough report published in the journal Science, October 18, 1996, provides the first true molecular evidence conclusively linking components in tobacco smoking to lung cancer.
		Although scientists have been convinced in the past that smoking causes lung cancer, the strong statistical associations did not provide absolute proof.
		This paper absolutely pinpoints that mutations in lung cancer cells are caused by benzopyrene.
	www.sarnia.com /groups/antidrug/mjmeds/mjcancr.html (288 words)

	Marijuana Policy Project: Indiana
		When exposed to heat, these compounds react, subjecting the smoker to some 2,000 chemicals including hydrogen cyanide, ammonia, carbon monoxide, acetaldehyde, acetone and phenol as well as carcinogens found in tobacco smoke: benzopyrene, benzoanthracene, benzene and nitrosamine.
		Benzopyrene, in particular, has been implicated in lung cancer and is known to suppress a gene (P53) that governs cell growth.
		It is true that no study has definitively linked marijuana smoking to lung cancer, but this is because a high percentage of marijuana smokers are also tobacco smokers and it is difficult to untangle the two effects.
	www.mpp.org /IN/news_2601.html (840 words)

	Charbroil - Wikipedia, the free encyclopedia
		It also does not dry out the meat.
		However, studies have shown that charbroiled (and barbecued) food may contain benzopyrene, a known carcinogen.
		This page was last modified 13:51, 19 November 2005.
	en.wikipedia.org /wiki/Charbroil (116 words)

	CNN - Local News - Toxic wastes endanger new Fenway ballpark - August 4, 2000
		That could prove troublesome to the team, which was denied a state-financed environmental contingency fund as part of a $313 million government subsidy bill approved by the Legislature last week.
		Records show high concentrations of dangerous benzopyrene and a half-dozen other hazardous compounds were detected last year following an underground fuel oil spill at 1265 Boylston St. The Sox plan to build a service area and players' garage on the site as part of the team's $665 million ballpark project.
		And while its primary threat is exhibited when the substance becomes airborne or is ingested, benzopyrene is also dangerous when it comes in contact with the skin.
	archives.cnn.com /2000/LOCAL/northeast/08/04/boh.ballpark.toxic.waste (993 words)

	Nat' Academies Press, Fetal Research and Applications: A Conference Summary (1994)
		Knowledge of aromatic hydrocarbon (Ah) receptor differences allowed investigators to give benzopyrene to pregnant mice and demonstrate that the offspring of mice with the low-affinity receptor had more birth defects and in utero toxicity.
		This finding is supported by work in humans showing that pregnant women with the low-affinity Ah receptor had babies with more birth defects than mothers with the high-affinity receptor, despite smoking the same number of cigarettes.
		In the study, all six of the DME genes were activated by benzopyrene and by dioxin.
	www.nap.edu /books/0309051762/html/42.html (764 words)

	Eurofood: Sunflower oil contaminated - Brief Article (Site not responding. Last check: 2007-10-13)
		At the end of April, the contamination of Italian high oleic sun flower oil with benzopyrene was discovered in the Netherlands.
		Benzopyrene is a PAC which is considered to be carcinogenic.
		Two Dutch manufacturers of baby food had bought the high oleic sun flower oil and they have now taken all the necessary precautionary measures.
	www.findarticles.com /p/articles/mi_m0DQA/is_2000_July_6/ai_63857280 (189 words)

	Nicotine Least Guilty
		Tar, which is a composite of benzopyrene, nitrosamines and other substances produced by cigarette combustion, is jointly responsible for lung cancer.
		Now, according to the British researchers, it has been discovered that although it is true that a filter retains a certain amount of nicotine, it increases by about [measurement illegible] the amount of carbon monoxide absorbed by the smoker.
		There is no longer any doubt about this....Tar reduces our defences against cancer; in particular it paralyzes the bronchial defensive systems, so that if the unknown cause of cancer attacks a smoker, it finds his defences stripped.
	tobaccofreedom.org /issues/documents/addiction/guilty (1354 words)

	Sloan-Kettering - Dinshaw J. Patel, Ph.D.
		Patel's research focuses on identifying the structure of DNA as it binds with carcinogens and antitumor agents.
		One of the carcinogens he studies is benzopyrene, which is found in cigarette smoke.
		He is trying to learn how benzopyrene binds to DNA and how the resulting damage induces mutations that can lead to the development of tumors.
	www.mskcc.org /prg/mrg/bios/452.cfm (165 words)

	Protein Damage Through Heating (Site not responding. Last check: 2007-10-13)
		There are more than twenty known, with the two most notable being benzopyrene and quinoline compounds.
		During barbecuing, for example, the fat from the meat drips onto the charcoal producing benzopyrene which then filters back up into the meat.
		A one-pound, well done, charcoal -broiled steak contains 4-5 micrograms of benzopyrene, an amount equal to what a person would get from smoking 600 cigarettes, stated Dave Townsend, an industry researcher who testified before a Minnesota tobacco trial.
	www.innvista.com /health/nutrition/amino/pdamage.htm (664 words)

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