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Topic: Bert Sakmann


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  Bert Sakmann Biography | World of Scientific Discovery
Bert Sakmann, along with physicist Erwin Neher, was awarded the 1991 Nobel Prize in physiology or medicine for inventing the patch clamp technique.
Sakmann's early interest in ion channels was stimulated by two papers published in 1969 and 1970 that gave strong evidence for the existence of ion channels.
Sakmann has continued to work with other research teams, altering the genes for identified ion channels in order to trace the molecules in the channel responsible for opening and closing the ion pore.
www.bookrags.com /biography/bert-sakmann-wsd   (727 words)

  
 Bert Sakmann - Wikipedia, the free encyclopedia
Bert Sakmann (born June 12, 1942) is a German cell physiologist.
Born in Stuttgart, Sakmann enrolled in Volksschule in Lindau, and completed the Wagenburg gymnasium in Stuttgart in 1961.
Sakmann joined the membrane biology group the in 1979.
en.wikipedia.org /wiki/Bert_Sakmann   (333 words)

  
 Bert Sakmann - Hutchinson encyclopedia article about Bert Sakmann   (Site not responding. Last check: 2007-10-16)
German cell physiologist who was awarded a Nobel Prize for Physiology or Medicine in 1991 with Erwin Neher for their discovery of how gatelike structures (ion channels) regulate the flow of ions into and out of cells.
In 1976 Sakmann worked with Neher to develop a technique called the patch-clamp technique, which greatly enhanced the ability of researchers to measure the electrical activity of nerves and revolutionized the study of ion channels in membranes.
Sakmann was born in Stuttgart and trained as a doctor at the University of Stuttgart.
encyclopedia.farlex.com /Bert+Sakmann   (264 words)

  
 Untitled   (Site not responding. Last check: 2007-10-16)
Along with Erwin Neher, Bert Sakmann developed the patch clamp technique to record the small ionic currents (only a few picoamperes) that flow through a single ion channel in neuronal membranes.
The first recordings of native ion channels in biological membranes were made by Bert Sakmann and Erwin Neher using an innovative modification of the voltage-clamp method.
The primary difficulty for Sakmann and Neher in their development of the patch clamp method was noise.
nobel-prize-winners.com /sakmann.html   (339 words)

  
 [No title]   (Site not responding. Last check: 2007-10-16)
BIOGRAPHICAL NOTE: Bert Sakmann studied at the universities of Tübingen and Munich, graduating in 1967.
Bert Sakmann’s admiration for his supervisor was to find tangible expression in 1993, through the establishment of the Bernard Katz Minerva Center for Cell Biophysics, a joint venture of the Max-Planck Institute for Medical Research in Heidelberg where Bert Sakmann is Director, the Hebrew University of Jerusalem and the Technicon-Israel Institute of Technology in Haifa.
Professor Sakmann’s development of the patch-clamp with Erwin Neher for measuring electrical activity and chemical flow across cell membranes and single ion channels resulted in a technique is now common place in laboratories throughout the world.
www.acadeuro.org /filesNov06/events/Sakmann.doc   (795 words)

  
 The University of Melbourne - Honorary Degree - Professor Bert Sakmann   (Site not responding. Last check: 2007-10-16)
Bert Sakmann studied at the universities of Tübingen and Munich, graduating in 1967.
Professor Sakmann's important discovery of the patch-clamp technique for measuring electrical activity and chemical flow across cell membranes resulted in a technique now used in laboratories throughout the world.
Bert Sakmann's work has attracted many prestigious awards, among them the Spencer and Gross-Horwitz prizes and Feldberg Prize of the Feldberg Foundation of London.
www.unimelb.edu.au /ExecServ/honcausa/citation/sakmann.html   (377 words)

  
 [No title]
The two German cell physiologists Erwin Neher and Bert Sakmann have together developed a technique that allows the registration of the incredibly small electrical currents (amounting to a picoampere - 10-12A) that passes through a single ion channel.
Neher and Sakmann have shown which parts of the molecule that constitute the "sensor" and the interior wall of the channel.
With the help of the technique of Neher and Sakmann it is now possible to tailormake drugs, to achieve an optimal effect on particular ion channels of importance in a given disease.
www.alternativesolutions.net /pressrelease.htm   (1911 words)

  
 Ion Channels - explains the Electro Acuscope and Myopulse
The patch clamp method of Sakmann and Neher, a technology which enables the examination of individual ion channels, was honored with a Nobel Prize and has resulted in the foundation of molecular electrophysiology as a recognized science.
After numerous futile experiments and constant improvements, Neher and Sakmann finally succeeded in 1976 to measure the ionic current of single channels in the cell membrane of a muscle fiber.
When Sakmann joined the Max Planck Institute in Heidelberg, the institute began to reorient itself and focus on the molecular and cellular basis of life.
www.thorpinstitute.com /html/P-ion_channels.html   (1140 words)

  
 diabetes   (Site not responding. Last check: 2007-10-16)
He was born in 1944 at Landsberg in Germany and trained originally as a physicist in Munich and at the University of Wisconsin.
He shared the Nobel Prize for Physiology or Medicine in 1991 with Bert Sakmann for his studies on ion channels and beta-endorphin.
Neher and Sakmann demonstrated that beta-endorphin acts not only on nerves in the brain to regulate their secretion of neurotransmitters but also, via calcium channels, acts on the walls of arteries in the brain.
www.probertencyclopaedia.com /cgi-bin/xphrase.pl?keyword=diabetes   (615 words)

  
 Bert Sakmann, doctor honoris causa
Bert Sakmann nace en Stuttgart, en el sur de Alemania, en 1942.
Sakmann hacia Bernard Katz, hasta tal punto que ha dedicado parte del premio Nobel a la creación de una fundación que lleva su nombre.
Bert Sakmann comenzó a colaborar con otros equipos de investigadores, especialmente biólogos moleculares.
www.ua.es /va/presentacion/doctores/sakmann/laudatio.html   (945 words)

  
 Erwin Neher Biography | World of Anatomy and Physiology
Erwin Neher, along with Bert Sakmann, was awarded the 1991 Nobel Prize in physiology or medicine for the development of the patch clamp technique.
The use of this technique enabled Neher and Sakmann to forge new paths in the study of membrane physiology and to understand the structure and functions of ion channels found in the plasma membranes of most body cells.
From 1975 to 1976, Neher was a research associate in the department of physiology at Yale University, and much of the data for the paper on patch clamps came from the Yale studies.
www.bookrags.com /biography/erwin-neher-wap   (976 words)

  
 Bert Sakmann - Wikipedia, the free encyclopedia   (Site not responding. Last check: 2007-10-16)
Bert Sakmann (born June 12, 1942 in Stuttgart) is a German cell physiologist.
Sakmann enroled in Volksschule in Lindau, and completed the Wagenburg gymnasium in Stuttgart in 1961.
In 1991 he received the Nobel prize for Physiology or Medicine together with Erwin Neher, with whom he had worked in Göttingen.
88.208.194.172 /wiki/index.php/Bert_Sakmann   (275 words)

  
 Bert Sakmann - Wikipedia
Bert Sakmann ist Professor und Direktor des Max-Planck-Instituts für medizinische Forschung in Heidelberg.
Sakmann habilitierte sich an der Georg-August-Universität Göttingen und forschte am Max-Planck-Institut für biophysikalische Chemie in Göttingen.
Informationen der Nobelstiftung zur Preisverleihung 1991 für Bert Sakmann (englisch)
de.wikipedia.org /wiki/Bert_Sakmann   (421 words)

  
 Nobel Laureate Erwin Neher to speak   (Site not responding. Last check: 2007-10-16)
Neher won the Nobel Prize with Bert Sakmann of the Max-Planck-Institute for medical biology in Heidelberg, Germany, for discoveries concerning the function of single ion channels in cells.
He and Sakmann were awarded the Nobel for developing a technique that allows the registration of the incredibly small electrical currents that pass through a single ion channel.
Neher and Sakmann showed which parts of the molecule constitute the "sensor" and the interior wall of the channel.
www.news.cornell.edu /chronicle/01/3.29.01/Neher.html   (372 words)

  
 Single Spine Ca2+ Signals Evoked by Coincident EPSPs and Backpropagating Action Potentials in Spiny Stellate Cells of ...
Brecht M, Sakmann B (2002a) Whisker maps of neuronal subclasses of the rat ventral posterior medial thalamus, identified by whole-cell voltage recording and morphological reconstruction.
Brecht M, Sakmann B (2002b) Dynamic representation of whisker deflection by synaptic potentials in spiny stellate and pyramidal cells in the barrels and septa of layer 4 rat somatosensory cortex.
Feldmeyer D, Sakmann B (2000) Synaptic efficacy and reliability of excitatory connections between the principal neurones of the input (layer 4) and output layer (layer 5) of the neocortex.
www.jneurosci.org /cgi/content/full/24/7/1689   (8286 words)

  
 Nobel Prize - the foundation of Electro Acuscope and Myopulse
Sakmann, a medical doctor, said he was working in an experiment in his laboratory at the Max-Planck Institute for Medical Research in Heidelberg, Germany, when he received a telephone call announcing that he had won the prize.
Sakmann said that after spending seven years developing the technique, he and Dr. Neher had spent the last decade applying it to describe precisely the structure and function of single ion channels, particularly in the brain.
Sakmann, who enjoys playing tennis and soccer, is a man with a good sense of humor.
www.thorpinstitute.com /html/nobel_prize.html   (1455 words)

  
 Intro Sakmann   (Site not responding. Last check: 2007-10-16)
Bert Sakmann is Head of the Department of Cell Physiology at the Max Planck Institute for Medical Research in Heidelberg, Germany.
The overall goal of his research is to elucidate the mechanisms of fast signalling within nerve cells, between nerve cells and of long-term changes in their synaptic coupling.
In 1991, Bert Sakmann was awarded the Nobel Prize in Physiology or Medicine together with Erwin Neher for the "discoveries concerning the function of single ion channels in cells" (http://nobelprize.org/medicine/laureates/1991/index.html).
www.uib.no /med/biomed/sbmb/seminarer/2005/intro/sakmann.htm   (163 words)

  
 [ISI Highly Cited Researchers Version 1.1]
Bollmann, J.H., Sakmann, B., Gerard, J., Borst, G..
Lubke, J., Egger, V., Sakmann, B., Feldmeyer, D..
Wu, L.G., Westenbroek, R.E., Borst, J.G.G., Catterall, W.A., Sakmann, B..
hcr3.isiknowledge.com /formViewCharacteristic.cgi?table=Publication&link1=Biography&id=57   (1352 words)

  
 Bert Sakmann (apunt biogràfic)
L'admiració de Bert Sakmann cap al seu mestre perdura encara avui en dia, fet que l'ha induït a la creació de la Fundació Bernard Katz.
Bert Sakmann va començar llavors a col·laborar amb altres grups, biòlegs moleculars primordialment, amb la finalitat d'alterar els gens que codifiquen els canals iònics, i, en definitiva, modificar-ne l'estructura molecular.
El 1983 Bert Sakmann va ser nomenat membre de la Societat Max Planck i posteriorment director del Departament de Fisiologia Cel·lular de l'Institut Max Planck de Göttingen (1985).
www.ua.es /va/presentacion/doctores/sakmann/apunte.htm   (496 words)

  
 Ion Channels and the Award of the Nobel Prize to Sakmann und Neher   (Site not responding. Last check: 2007-10-16)
The patch clamp method of Sakmann and Neher, a technology which enables the examination of individual ion channels, was honoured with a Nobel Prize and has resulted in the foundation of molecular electrophysiology as a recognized science.
After numerous futile experiments and constant improvements, Neher and Sakmann finally succeeded in 1976 to measure the ionic current of single channels in the cell membrane of a muscle fibre.
In order to investigate the elementary processes of synaptic signal transmission in close cooperation with molecular biologists, Sakmann moved his laboratory from Göttingen, where he had been collaborating with Erwin Neher for sixteen years, to Heidelberg, one of the best molecular biology centres in Germany.
www.bio-pro.de /en/region/rhein/magazin/00971   (1211 words)

  
 Bert Sakmann   (Site not responding. Last check: 2007-10-16)
From 1969 to 1970 Sakmann served as a research assistant in the department of neurophysiology at the Max Planck Institute for Psychiatry and then finished his postdoctoral studies in the department of biophysics at University College, London.
In 1979 Sakmann became a research associate in the Max Planck Institute's membrane biology group.
He was made head of the membrane physiology unit in 1983, and he became director of the institute's department of cell physiology two years later.
medicine.nobel.brainparad.com /bert_sakmann.html   (233 words)

  
 Bert Sakmann - Autobiography
I was born during the second world war in Stuttgart, the capital of Swebia, as the first of two children.
My father, Bertold Sakmann, was the director of a theatre, the third son of a physician whose family had lived in southern Germany for several generations.
My mother, Annemarie Sakmann, was a physiotherapist and was born in Bangkok, the second child of a Prussian physician who served as doctor to the King of Siam and was the founder of the first hospital in Siam.
nobelprize.org /nobel_prizes/medicine/laureates/1991/sakmann-autobio.html   (1721 words)

  
 Bert Sakmann Erwin Neher Nobel Prize in Physiology or Medicine June 12 German   (Site not responding. Last check: 2007-10-16)
Bert Sakmann blev født i Stuttgart under 2.
Den omhandler derfor videnskabsmændene Bert Sakmann og Erwin Neher, som i 1991 modtog nobelprisen i kategorien Medicin, for deres...
Awarded the $1 million prize by the Nobel Assembly of the Karolinska Institute were Erwin Neher, 47, and Bert Sakmann, 49, of the Max-Planck Institutes in Goettingen and Heidelberg, Germany.
en.powerwissen.com /vWDu1ioKhc7F9IKaOPg5YA==_Bert_Sakmann.html   (153 words)

  
 News, Publications, Ausländerbehörde, Award, scholar, scientist, fellowships, Alexander von Humboldt Foundation - ...
The lectureship is financed from funds of the Bert Sakmann Foundation that is administered by the Alexander von Humboldt Foundation.
In 1991 Sakmann was awarded the Nobel Prize of Medicine.
Professor Sakmann will be in the audience of the honorary lecture on January 26.
www.humboldt-foundation.de /en/aktuelles/presse/pn_archiv_2000/2000_02.htm   (363 words)

  
 Erwin Neher   (Site not responding. Last check: 2007-10-16)
German physicist, winner with Bert Sakmann in 1991 of the Nobel Prize for Physiology or Medicine for their research into basic cell function and for the development of the patch-clamp technique, a laboratory method that can detect the very small electrical currents produced by the passage of ions through the cell membrane.
Neher and Sakmann presented their patch-clamp findings at a scientific gathering in 1976.
Neher and Sakmann used a thin glass pipette, one-thousandth of a millimetre in diameter, that was fitted with an electrode to detect the flow of individual ions through the ion channels of a cell membrane.
medicine.nobel.brainparad.com /erwin_neher.html   (314 words)

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