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Topic: Beta clamp

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	Walthers Entertainment World - Cable microphones
		The Beta 53 (and its wireless version the WBH53) is a fully adjustable omnidirectional condenser microphone, designed for applications where unconspicuous appearance and incredible sound quality are required.
		The uniform cardioid polar pattern of the Beta 87C enables users to effectively reject ambient noise arriving at the rear of the microphone, an attribute that will be especially appealing to users of personal monitors and others who frequently experience undesirable sounds bleeding into their mixes.
		The Shure Beta 98H/C (also available as the WB98H/C for use with wireless systems) is a premium cardioid condenser instrumental microphone that clamps onto the bell of wind instruments or onto the rim of percussion instruments.
	www.wew.com.au /products/sales-mics-cable.htm (3335 words)

	Mechanism of Loading the Escherichia coli DNA Polymerase III beta Sliding Clamp on DNA. BONA FIDE PRIMER/TEMPLATES ...
		by a slower decrease attributed to the release of the clamp on
		of the clamp on DNA (17, 18, 23).
		trigger the clamp loader to hydrolyze ATP and release the clamp
	www.jbc.org /cgi/content/full/278/12/10033 (4559 words)

	DNA Replication II
		However, linearization of the nicked circle with a restriction endonuclease releases beta from the DNA; that is, beta is a sliding clamp.
		In panel (A) the hexameric DnaB helicase encircles the lagging strand, and the two core polymerases are held to the two strands of DNA by beta clamps.
		Upon completion of an Okazaki fragment, the lagging strand polymerase releases from DNA by severing its tie to the beta clamp, leaving the beta ring behind on the finished fragment as in panel (B).
	oregonstate.edu /instruction/bb492/lectures/DNAII.html (1924 words)

	Print the story
		New research published this week in Molecular Cell from the laboratory of Rockefeller University's Michael O'Donnell, a Howard Hughes Medical Institute Investigator, now shows that one of these proteins, the beta sliding clamp, serves as a toolbelt from which the correct proteins are retrieved to enable DNA replication in the face of DNA damage.
		The replication machinery inside the cell's nucleus is made up of a collection of enzymes including DNA polymerases, sliding clamps and clamp loaders.
		As the ring-shaped beta sliding clamp works its way along the DNA double helix, a network of proteins work together to unwind the two strands.
	www.physorg.com /printnews.php?newsid=6605 (384 words)

	Interactive Fly, Drosophila
		For example, the Escherichia coli clamp (the beta subunit) is active as a dimer, while the eukaryotic and T4 phage clamps (PCNA and gp45, respectively) are active as trimers.
		beta is more stable in solution (Kd The remarkable processivity of cellular replicative DNA polymerases derive their tight grip to DNA from a ring-shaped protein that encircles DNA and tethers the polymerase to the chromosome.
		The amino acid sequences of 11 beta and 13 PCNA proteins from different organisms have been aligned and studied to gain further insight into the relation between the structure and function of these sliding clamps.
	www.sdbonline.org /fly/polycomb/pcna2b.htm (3602 words)

	Ion channel Literature - Single channel properties of recombinant GABAA receptors containing gamma 2 or delta subtypes ... (Site not responding. Last check: 2007-10-24)
		The single channel conductance of alpha 1 beta 3 channels was low (13 pS) compared with that of alpha 1 beta 3 delta and alpha 1 beta 3 gamma 2L channels (27 pS).
		The alpha 1 beta 3 gamma 2L channel exhibited three open states, while the alpha 1 beta 3 and alpha 1 beta 3 delta channels exhibited only two open states with mean dwell times similar to those of the two shorter open states of the alpha 1 beta 3 gamma 2L channel.
		Addition of a delta subunit to form the alpha 1 beta 3 delta heterotrimer altered the single channel conductance and the kinetic properties of the closed components, but did not affect the GABA sensitivity of the receptor nor the open state kinetics.
	www.ionchannels.org /showabstract.php?pmid=9423172 (602 words)

	Ion channel Literature - On the role of endogenous G-protein beta gamma subunits in N-type Ca2+ current inhibition by ... (Site not responding. Last check: 2007-10-24)
		Expression of the C-terminus domain of beta-adrenergic receptor kinase 1 (beta ARK1), which contains the consensus motif (QXXER) for binding G beta gamma, reduced the fast (pertussis toxin (PTX)-sensitive) and voltage-dependent inhibition of ICa by noradrenaline and somatostatin, but not the slow (PTX-insensitive) and voltage-independent inhibition induced by angiotensin II.
		Overexpression of G beta 1 gamma 2, which mimicked the voltage-dependent inhibition by reducing ICa density and enhancing basal facilitation, occluded the voltage-dependent noradrenaline- and somatostatin-mediated inhibitions but not the inhibition mediated by angiotensin II.
		Co-expression of the C-terminus of beta ARK1 with beta 1 and gamma 2 subunits prevented the effects of G beta gamma dimers on basal Ca2+ channel behaviour in a manner consistent with the sequestering of G beta gamma.
	www.ionchannels.org /showabstract.php?pmid=9490860 (448 words)

	POL30 -
		To preserve genomic beta DNA from common endogenous and exogenous base and sugar damage, cells are provided with multiple base excision repair (BER) pathways: the DNA polymerase (Pol) beta-dependent single nucleotide BER and the long-patch (2-10 nt) BER that requires PCNA.
		A cDNA encoding the proliferating cell nuclear antigen (PCNA) from Brassica napus (oilseed rape) was shown to complement the lethal deletion mutation in the PCNA gene (delta POL30) of Saccharomyces cerevisiae.
		The sliding clamps of bacteriophage T4 (gp45), Escherichia coli (beta clamp), and yeast (PCNA) are required for processive DNA synthesis by their cognate DNA polymerases.
	www.ihop-net.org /UniPub/iHOP/gi/32749.html (1520 words)

	[No title] (Site not responding. Last check: 2007-10-24)
		Beta 1 AL Beta 1 al shock absorbed
		Beta 2 AL Beta 2 AL shock absorbed
		Beta 3 AL Beta 3 AL shock absorbed
	www.baltronics.com.au /tred_1_update.htm (465 words)

	[Frontiers in Bioscience, 4, d849-858, December 1, 1999]
		Clamps have a common ring shape that is able to rap around DNA and slide along double helical DNA freely in both directions (8-10) so that their interactions with DNA polymerases stabilize the enzymes on template.
		The head to tail connection at the interface of clamp monomers is maintained by stable interactions of hydrophobic residues.
		It is apparent that the existence of a DNA sliding clamp is a necessity for all organisms.
	www.bioscience.org /1999/v4/d/tsurimot/fulltext.htm (7059 words)

	Evolutionary clues to DNA polymerase III {beta} clamp structural mechanisms -- Neuwald 31 (15): 4503 -- Nucleic Acids ...
		clamp is mediated by the clamp loader complex (9–11),
		LM06747 to A.F.N. Jeruzalmi,D., O’Donnell,M. and Kuriyan,J. (2002) Clamp loaders and sliding clamps.
		O’Donnell,M., Jeruzalmi,D. and Kuriyan,J. (2001) Clamp loader structure predicts the architecture of DNA polymerase III holoenzyme and RFC.
	nar.oxfordjournals.org /cgi/content/full/31/15/4503 (5563 words)

	Figure H4 (Site not responding. Last check: 2007-10-24)
		The clamp loader (gamma complex) of DNA polymerase III holoenzyme puts a beta clamp around an RNA primer using ATP energy.
		The beta ring is constrained to the primer since it cannot slide over single-stranded DNA.
		Since beta is needed to tether core polymerase to DNA, the end result is a primase-to-polymerase switch.
	oregonstate.edu /instruction/bb331/lecture07/FigH4.html (338 words)

	Shure - Accessories - A98KCS Universal Horn Mount
		The Model A98KCS Horn Mount is a versatile device that securely attaches Shure SM98A, Beta 98, or WM98 microphones to a horn, wind, or reed instrument in the exact position desired while protecting the instrument and its finish.
		A short gooseneck (165 mm [6-1/2 in.]) attached to the clamp terminates in a shock-mount adapter for the SM98 or WM98 microphone.
		The A98KCS Horn Mount is a versatile device that securely attaches Shure SM98A, Beta 98, or WM98 microphones to a horn, wind, or reed instrument in the exact position desired while protecting the instrument and its finish.
	www.shure.com /ProAudio/Products/Accessories/us_pro_A98KCS_content (175 words)

	Mechanism of beta Clamp Opening by the delta Subunit of Escherichia coli DNA Polymerase III Holoenzyme -- Stewart et ...
		Mechanism of beta Clamp Opening by the delta Subunit of Escherichia coli DNA Polymerase III Holoenzyme -- Stewart et al.
		(the sliding clamp (6, 7)); and the multisubunit
		clamp is a tight dimer and remains a dimer even when diluted to a concentration of 50
	www.jbc.org /cgi/content/full/276/22/19182 (3753 words)

	Interaction of the beta sliding clamp with MutS, ligase, and DNA polymerase I -- López de Saro and O'Donnell 98 ...
		Interaction of the beta sliding clamp with MutS, ligase, and DNA polymerase I -- López de Saro and O'Donnell 98 (15): 8376 -- Proceedings of the National Academy of Sciences
		clamps may serve to target Pol I to the lagging strand for removal of the RNA used to initiate each fragment.
		The DNA sliding clamp was originally identified as a key component of the chromosomal replicating machine.
	www.pnas.org /cgi/content/full/98/15/8376 (3797 words)

	Brainstorms: Convergence or Divergence?
		Sliding DNA clamps are ring-shaped proteins that allow DNA polymerase to achieve high processivity during chromosome replication by tethering the polymerase catalytic subunit to DNA.
		In the case of DNA sliding clamps, the basic function has remained the same across all the groups, but eukaryotes attach a number of extra proteins to the clamps in comparison to prokaryotes, and archaebacteria are well-known extremophiles.
		Too me it seems like the function is basically "sliding clamp" (surprise surprise), with the purpose of serving as an attachment to hold other components near to the DNA strand, and it seems that a variety of ring structures could serve this purpose.
	www.iscid.org /boards/ubb-get_topic-f-6-t-000121-p-5.html (8849 words)

	Brainstorms: Convergence or Divergence?
		Starting with the Clamps, it has been suggested that the PCNAs and the Beta Clamps are likely related because they look so similar, and also because they (supposedly) share some very remote sequence similarity (which we might expect if they really were related).
		Once more for good measure, when we BLAST the Beta Clamp, we find, for example, that a yeast proteasome component is actually one of the top scores against the bacterial Beta Clamp.
		Since Beta is much bigger than PCNA, this means that there is a block of sequence (>100 aa's) in the Beta Clamp that does not align to PCNA at all, as far as I can see.
	www.iscid.org /boards/ubb-get_topic-f-6-t-000121-p-6.html (4952 words)

	BMB 615 Outline - DNA Polymerases
		Made from beta subunit in bacteria, PCNA in Eukayotes and Archaea, and gp45 in T4 bacteriophage.
		There are other associated proteins that attach to the clamp loader; for example, a subunit that functions to couple the clamp loader to single-stranded DNA binding proteins.
		The three gamma subunits are ATPases (AAA+ family of ATPases), and act as the motor of the clamp loader by uncovering parts of delta (covered by delta' in the resting state) upon ATP hydrolysis.
	structure.med.miami.edu /bmb615_DNApol_notes.html (947 words)

	Shure - Wired Microphones - Beta 98H/C
		The Shure Beta 98H/C and the wireless version WB98H/C is a premium cardioid condenser instrumental microphone that clamps onto the bell of wind instruments or onto the rim of percussion instruments.
		The Beta 98H/C and WB98H/C feature transformerless preamplifier circuitry, which improves linearity across the full frequency range.
		Beta 98H/C with integrated shock mount and attached preamplifier.
	shure.com /ProAudio/Products/WiredMicrophones/us_pro_Beta98H-C_content (394 words)

	CardioMed Supplies Products - New Products
		This clamp is constructed of durable plastic and strong metal components.
		Made from polypropylene plastic with a latch closure system, our Beta Clamp is ideal for the occlusion of compliant silicone or soft PVC tubing.
		Injection Cap can be used on any line where medication may need to be administered or wherever a sample may need to be drawn from.
	www.cardiomed.com /products/new.htm (263 words)

	ScienceDaily: Clearing Jams In Copy Machinery
		New research published this week in MolecularCell from the laboratory of Rockefeller University's Michael O'Donnell,a Howard Hughes Medical Institute Investigator, now shows that one ofthese proteins, the beta sliding clamp, serves as a toolbelt from whichthe correct proteins are retrieved to enable DNA replication in theface of DNA damage.
		As thering-shaped beta sliding clamp works its way along the DNA doublehelix, a network of proteins work together to unwind the two strands.Polymerases then add, in assembly line fashion, nucleotide bases -- thebuilding blocks that make up DNA -- to convert the now-single-strandedtemplates into two new duplex DNA molecules.
		"Onepossibility is that the beta clamp may sense when Pol III stalls,triggering a change in beta that pulls the polymerase from the primedsite, allowing Pol IV to take over synthesis," O'Donnell says.
	www.sciencedaily.com /releases/2005/09/050920082649.htm (1700 words)

	Eagnas Professional Stringing Machine
		The Beta has the extra feature of the 360 degree swivel glide bar tray table, which the GAMMA 6000 does not have it.
		All-metal swivel clamp base with spring-action lever: much easier to use and no muscle needed.
		Metal swivel clamps, reel holder, all-metal tool tray with pad, all-metal machine base with level-adjustable pads, height adjustable, metal swivel clamp base with regular lever but without spring-action lever - just need half turn to lock and release the base.
	www.eagnas.com /upright.html (5632 words)

	Beta Adapters (Site not responding. Last check: 2007-10-24)
		The new and exclusive BETA-ADAPTER allows a clamping junction to be inserted into virtually any hydraulic line.
		The junction adapter provides a point of union for hydraulic runs transitioning from one form of conveyance to another (i.e., hose to tubing).
		Once inserted into the customized Beta-Adapter clamp body, the junction point is securely clamped, fighting the effects of vibration, insuring a leak-free system.
	www.cushaclamp.com /betaad.html (177 words)

	Genetic Interactions between the Escherichia coli umuDC Gene Products and the {beta} Processivity Clamp of the ...
		clamp showing the positions of missense mutations as viewed from the face bearing the extruding C-terminal tails of each protomer (A), and the side (B), corresponding to a 90° rotation of that shown in panel A. The crystal structure of the homodimeric
		Structural analyses of gp45 sliding clamp interactions during assembly of the bacteriophage T4 DNA polymerase holoenzyme.
		The Gp43 DNA polymerase binds to the same face of the sliding clamp as the clamp loader.
	jb.asm.org /cgi/content/full/183/9/2897 (7364 words)

	Forceware 67.66 Official Beta (Drivers Dated 1/18/2005) - nV News Forums
		It's a little confusing now that Nvidia is releasing official beta drivers.
		It looks like the negative LOD clamp is missing in these...
		If you read the literature that was in the same FTP folder as these, you'll see that Nvidia is realllly pushing Nview.
	www.nvnews.net /vbulletin/showthread.php?t=44227&page=2 (714 words)

	Interaction of the Sliding Clamp {beta}-Subunit and Hda, a DnaA-Related Protein -- Kurz et al. 186 (11): 3508 -- The ...
		Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E.
		The beta clamp targets DNA polymerase IV to DNA and strongly increases its processivity.
		Kongsuwan, K., Josh, P., Picault, M. J., Wijffels, G., Dalrymple, B. The Plasmid RK2 Replication Initiator Protein (TrfA) Binds to the Sliding Clamp {beta} Subunit of DNA Polymerase III: Implication for the Toxicity of a Peptide Derived from the Amino-Terminal Portion of 33-Kilodalton TrfA.
	jb.asm.org /cgi/content/full/186/11/3508 (5130 words)

	[No title]
		Has problems if you try shadowing the rim light.
		Added clamping to the alpha and beta angles to avoid instability around 90 degree grazing angles.
		This is not a correct solution, but it should at least avoid bright speckles most of the time.
	www.renderman.org /RMR/Shaders/MKShaders/MKfancysurf.sl (308 words)

	nV News Forums - Xtreme G 67.03's and 70.90 beta's Ready . . .
		- - Xtreme G 67.03's and 70.90 beta's Ready.
		the 70.90 XG betas will be up shortly.
		Beware, these drivers put my monitor into power save after 2 mins for no reason.
	www.nvnews.net /vbulletin/printthread.php?t=42019&pp=40 (306 words)

	In praise of the hyperglycemic clamp. A method for assessment of beta-cell sensitivity and insulin resistance -- Elahi ...
		The use of the hyperglycemic clamp and several of its
		Hyperglycemic Clamp Assessment of Insulin Secretory Responses in Normal Subjects Treated with Olanzapine, Risperidone, or Placebo
		Glucose-induced desensitization of the pancreatic beta -cell is species dependent
	care.diabetesjournals.org /cgi/content/abstract/19/3/278 (829 words)

	BMB615 - DNA polymerase section related PDB files (Site not responding. Last check: 2007-10-24)
		Human DNA Polymerase beta complexed with gapped DNA and Ddctp - 1BPY
		E. coli Pol III DNA clamp loader - delta/gamma3/delta' subunits - 1JR3
		You can use programs such as Pymol, Rasmol/Chime, Swiss-Pdb Viewer or Cn3D to view these pdb files (see links to these and other programs on the main Malhotra lab web page).
	structure.med.miami.edu /bmb615_DNApol_structures.html (164 words)

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