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| | NIH Guide: IMAGING PANCREATIC BETA CELL MASS, FUNCTION, OR INFLAMMATION |
 | | Insulin is produced in the pancreatic islet beta cell and released in response to a meal, or to elevations in plasma glucose and certain amino acids. |
 | | In the course of development of this technique, it would be of great clinical benefit to be able to identify the location, number, viability, growth and function of these grafts, and to noninvasively monitor their response to immune modulating therapy using imaging. |
 | | These include tagged antibodies to the beta cell surface, ligands for receptors specific to the beta cell, or agents whose contrast properties are "unmasked" by beta cell enzymes. |
| grants.nih.gov /grants/guide/rfa-files/RFA-DK-99-018.html (3754 words) |
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