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| | SSAT - 2005 Abstracts: Antibiotic Prophylaxis for Pancreatic Necrosis: Does the Choice Of Agent Make a Difference? (Site not responding. Last check: 2007-09-02) |
 | | Five relevant RCTs were identified: three evaluating a betalactam type regimen (175 patients) (Pederzoli 1993, Sainio 1995, Nordback 2001), and two a quinolone/imidazole combination (102 patients) (Schwarz 1997, Isenmann 2004). |
 | | Mortality was lower, but not significantly in betalactam (p=0.13, OR 0.45) and quinolone/imidazole (p=0.25, OR 0.45) subgroups. |
 | | Infected necrosis was not significantly reduced overall (p=0.1, OR 0.62), but was in the betalactam subgroup (p=0.02, OR 0.41) and not in the quinolone/imidazole subgroups (p=0.61, OR 1.29). |
| www.ssat.com /cgi-bin/abstracts/05ddw/SSAT_DDW05_188.cgi?affiliation=1 (330 words) |
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