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Topic: Biomolecule


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In the News (Thu 23 May 19)

  
  biomolecule - Search Results - MSN Encarta
A biomolecule is a chemical compound that naturally occurs in living organisms.
Biomolecules consist primarily of carbon and hydrogen, along with nitrogen, oxygen, phosphorus and sulfur.
The Biomolecule Toolkit is a library for modeling biological macromolecules such as proteins, DNA...
encarta.msn.com /biomolecule.html   (0 words)

  
 SurModics | Bringing Innovation Together
Immunoassay stabilizers that maintain the activity of antibodies, enzymes, and antigens in the dry state.
StabilCoat, StabilGuard, immunoassay stabilizer, biomolecule stabilizer, SC01, SC05, stabilize antibodies, stabilize enzymes, stabilize antigens, dry stabilization, blocking agent
StabilCoat Plus™ Immunoassay Stabilizer and StabilGuard Choice™ Biomolecule Stabilizer are formulated to improve the performance of protein arrays used in in vitro diagnostics and drug discovery.
rd.business.com /index.asp?epm=s.1&bdcq=Biomolecule&bdcr=3&bdcu=http://www.surmodics.com&bdcp=&partner=2662601&bdcs=nwuuid-2662601-25A25616-0579-6CC6-2D1F-238A1B1526E9-ym   (0 words)

  
  Biomolecule
A biomolecule is a compound that naturally occurs in living organisms.
Biomolecules consist primarily of carbon and hydrogen, along with nitrogen, oxygen, phosphorus and sulfur.
Biomolecules are necessary for the existence of all known forms of life.
www.knowledgefun.com /book/b/bi/biomolecule.html   (855 words)

  
  Biomolecule
A biomolecule is a chemical compound that naturally occurs in living organisms.
Biomolecules consist primarily of carbon and hydrogen, along with nitrogen, oxygen, phosphorus and sulfur.
Biomolecules are necessary for the existence of all known forms of life.
www.ibpassociation.org /encyclopedia/Chemistry/Biomolecule.php   (924 words)

  
 Patent 6,645,525
The biomolecule may be complexed with either one of the polymers, depending on the characteristics of the biomolecule, such as the charge of the biomolecule.
Preferably, the biomolecules in the microcarrier composition are in biologically active form or are immunogenic and are then released gradually in situ from the microcarrier when administered to a human or animal subject.
A microparticle composition for delivery of a biomolecule comprising a biomolecule incorporated in a complex comprising a cationic polymer ionically complexed with an anionic polymer, wherein the cationic polymer is polyethyleneimine and the anionic polymer is dextran sulfate.
www.pharmcast.com /Patents100/Yr2003/Nov2003/111103/6645525_Microcarriers111103.htm   (2719 words)

  
 Patent 7,141,374   (Site not responding. Last check: )
According to one aspect of the invention, the immobilized biomolecules are nucleic acid molecules or oligonucleotides.
According to the present invention, biomolecules are immobilized on a surface of a substrate having a first surface including a functional group for non-covalent attachment to a biomolecule.
Other interactions between biomolecules and coated substrates are, of course, possible and the above discussion is not intended to be exhaustive or limiting of the mechanisms, which may play a role in the immobilization of biomolecules on coated substrates in accordance with this invention.
www.pharmcast.com /Patents100/Yr2006/Nov2006/112806/7141374_Substrates112806.htm   (1531 words)

  
  One-step method for attachment of biomolecules to substrate surfaces - Patent 6143354
Biomolecules useful in the methods of the present invention are those that include moieties that are activated toward a substrate and/or ethylenically unsaturated monomers by oxidizing metal ions such that bonding occurs.
Biomolecules, which can be a mixture of different biomolecules, are present in the reaction mixture (preferably, in the form of a solution) in an amount sufficient to provide a desired level of biomolecule attachment.
By this it is meant that for a substrate to which there is a biomolecule, such as heparin, attached to a substrate surface, there is a reduction in the number of platelets attached to the substrate surface per unit area relative to the same substrate without the biomolecule attached thereto when contacted with human blood.
www.freepatentsonline.com /6143354.html   (5742 words)

  
 ELISA Technical Bulletin No. 2
The Universal Covalent surface, which is used to covalently immobilize biomolecules through abstractable hydrogen via UV activation of the functional group on the surface, must be protected from UV light prior to the activation process.
Typical biomolecule concentrations destined for immobilization to a hard plastic surface are in the µg/mL range.
Biomolecule immobilization to hard plastic surfaces, such as polystyrene 96 well plates, is primarily governed by the chemistry of the surface.
www.corning.com /Lifesciences/technical_information/techDocs/elisa2.asp?region=&language=   (3335 words)

  
 Theoretical Biology and Medical Modelling | Full text | Identification of biomolecule mass transport and binding rate ...
The first section of this paper presents the mathematical model used to describe diffusion-reaction of biomolecules inside cells during the course of the FRAP experiment, along with the numerical algorithm used to solve it and the approach developed for parameter estimation by nonlinear optimization.
The effects of heating (caused by the absorption of the laser beam by the sample and fluorophore) on the biomolecule mass transport and binding rate parameters are negligible.
A way to perform this is to use a biomolecule of the same molecular weight and class as the biomolecule under study, which does not react with the vacant binding site(s).
www.tbiomed.com /content/3/1/36   (7359 words)

  
 A Model for Binding of DNA and Proteins to Transfer Membranes
Hydrophobic regions on both the biomolecule and the membrane align with each other and layers of hydration surrounding both the membrane and biomolecule are excluded.
Biomolecules having secondary and tertiary structure are transported to the membrane surface by diffusion.
Transport of the biomolecules to the membrane surface by diffusion; 2.
www.pall.com /34696_27294.asp   (1998 words)

  
 RLE :: Micro / Nanofluidic BioMEMS Group
Biomolecule separation is a fundamental analytical and preparative technique in biology, medicine, chemistry, and industry.
In this project, we construct different nanofilter based separation devices and explore the steric and electrostatic partitioning of biomolecules with the nanofilter for size- or charge-fractionation of various biologically relevant macromolecules.
In addition to the application of biomolecule separation, the nanofilter based artificial sieving structures provide an ideal platform for the theoretical study of molecular dynamics and stochastic motion in confining spaces because of their precisely characterized environments.
www.rle.mit.edu /micronano/research_protein.htm   (876 words)

  
 Biomolecule sample immobilization (US5124041)
A filter system for separating and binding biomolecules contained in a solution includes a first filter means for selectively passing components of the solution that are smaller than the biomolecules, thereby concentrating the biomolecules in the solution.
Also included is a binding membrane means having an affinity for the biomolecules for binding the biomolecules to the binding membrane means, with the binding membrane means being located where the biomolecules are concentrated by the first filter means.
The concept is to concentrate the biomolecules of interest by means of the cut-off membrane in the vicinity of the binding membrane, thereby increasing the binding yield on the binding membrane.
www.delphion.com /details?pn10=US05124041   (439 words)

  
 Patterning method, substrate for biomolecule immobilization using the patterning method, and biochip employing the ...
Overall biochemical analysis of biochips where desired biomolecules are immobilized on specific zones of a silicon microchip using a semiconductor processing technique can easily provide important information.
Immobilization of biomolecules occurs on surfaces of slide glasses, silicon wafers, microwell plates, tubes, spherical particles, and porous films.
In this case, when the gold pattern is formed by photolithography, it is necessary to use room temperature and atmospheric pressure conditions because there is a likelihood of damage to the nanopores occurring under photolithographic deposition environment.
www.freshpatents.com /Patterning-method-substrate-for-biomolecule-immobilization-using-the-patterning-method-and-biochip-employing-the-substrate-dt20060824ptan20060188907.php   (4246 words)

  
 MedlinePlus: Biomolecule Test Could Bring Diagnostics to the Bedside   (Site not responding. Last check: )
This technology could lead to the development of low-cost medical diagnostic tests at patients' bedsides and could also be used for genetic profiling, disease monitoring and drug discovery, the scientists said.
A paper on the research is published in the March 9 issue of the journal Science.
This technique uses tiny customizable particles (thinner than the width of a human hair) that are each equipped with a barcoded ID and one or more probe regions that turn fluorescent when they detect specific biomolecules in a sample, the scientists explained.
www.nlm.nih.gov /medlineplus/news/fullstory_46325.html   (183 words)

  
 Biocompare - Biomolecules Search Help
The Biomolecule search tool is designed to assist you in finding specific proteins, enzymes, peptides, lipids, carbohydrates, and other biomolecule products.
If you are interested in a biomolecule with a certain species origin, you may narrow your search by selecting one of the options in the pulldown menu.
Affinity/Antibody binding tags and conjugates are those that are meant to allow purification of the biomolecule or binding with a standard antibody.
www.biocompare.com /help_biomol.asp   (702 words)

  
 Quantum Dot Conjugation Protocols - Amine EviTags
Biomolecule used with s-SMCC activated EviTags must have a free sulfhydryl group which can be obtained by using reducing agents (For example, either DTT or TCEP can be used).
Free biomolecule fractions will be represented by peaks with no fluorescence, but absorption at 260nm (for nucleic acid) or at 280nm (for protein).
Pool the fractions containing free biomolecule and quantify amount of unreacted biomolecule (biomolecule out) using standard assay (e.g., Beer's Law; Lowry or Bradford assays for protein).
www.evidenttech.com /life_sciences/protocols/evitag_protocols/quantum-dot-evitag-protocols-sulfhy.php   (524 words)

  
 Biostabilization
The biomolecule storage solution is used to preserve the activity of biomolecules like enzymes, antibodies, DNA, whole cells or cell membranes during the storage over a long time.
The PCR optimizer stabilizes biomolecules like enzymes and is used to increase the thermostability and the half-life period of the Taq Polymerase, so it is possible to realize more cycles.
The biomolecule storage solution is used to preserve the activity of biomolecules like enzymes, antibodies, DNA, whole cells or cell membranes during long-term storage.
www.sigmaaldrich.com /Brands/Fluka___Riedel_Home/Bioscience/Biostabilization.html   (847 words)

  
 Description of Research   (Site not responding. Last check: )
Photooxidation of biomolecules by reactive oxygen species is an important biological process associated with aging, disease and photodynamic therapy for cancer, and is also related to the destruction of atmospheric biomolecule aerosols.
With the current lack of reaction kinetics research on biomolecule aerosols, one primary goal of our research is to develop kinetic modes for reactions of bioaerosols.
Of particular interest are the interaction between micelle host and guest molecules, the structure and conformation of biomolecules encapsulated in the confined microenvironment, and photooxidation reactions within such "nano-reactors".
qcpages.qc.edu /Chemistry/liu_researchpage.htm   (994 words)

  
 SurModics | Products | In Vitro Technologies | Biomolecule Immobilization
Because of its flexibility and gentle coating conditions, the PhotoLink® approach is uniquely suited for attaching virtually all classes of biomolecules to a wide range of surfaces.
Immobilization of biomolecules by long tethers generally provides higher levels of retained activity than other surface modification methods.
Biomolecules can be immobilized over an entire surface or "printed" in specific patterns.
www.surmodics.com /pageDetail.aspx?pageId=103&menuId=105   (173 words)

  
 Boston University: National Emerging Infectious Diseases Laboratories   (Site not responding. Last check: )
The overall objective of this Core is to provide the necessary infrastructure for the expression and purification of biologic molecules including proteins, glycoproteins, peptides, and other biologics from the Risk Group 4 viral agents for investigators associated with the NEIDL.
We believe that this design maximizes the efficiency of research that will be performed under high containment in the Institute by minimizing the extensive downtime that would be required for conversion of a single flexible laboratory module.
For example, at the same time Kyasanur Forest Disease virus can be propagated for challenge studies in the BSL-4 Biomolecule Production Core laboratory, Francisella tularensis may be grown for the extraction and purification of capsule to be used in an experimental conjugate vaccine in the BSL-3 Biomolecule Production Core laboratory.
www.bu.edu /neidl/research/biomolecule/index.html   (548 words)

  
 Affinity Chromatography
Affinity chromatography is the purification of a biomolecule with respect to the specific binding of that biomolecule due to its chemical structure (Amersham Bioscience, 2003).
This property enables the ligand to bind to a biomolecule until washing, at which time the unbound biomolecules are washed away.
After the unbound substances are washed away, the bound biomolecule can then be eluted by changing the experimental conditions so that the biomolecule will release from the ligand (Amersham Bioscience, 2003).
www.bio.davidson.edu /Courses/Molbio/MolStudents/spring2003/WoodW/affchrom1.html   (445 words)

  
 MIT Biological Engineering Division
Toward the eventual goal of all-integrated microfluidic biomolecule analysis systems, currently we are focusing on the following two research areas.
Biomolecule separation using nanofluidic molecular sieve: Currently, most of biomolecule purification and separation uses random nanoporous materials as molecular sieving matrix.
The possibility of coupling such devices to mass spectrometry is also studied for a streamlined biomolecule analysis and identification.
web.mit.edu /be/people/han.htm   (391 words)

  
 WISH Research - The Effect of External Qi of Qigong on Biomolecule Conformation1 (Report 3)   (Site not responding. Last check: )
The effect of external Qi emitted by a Chinese Qigong master on biomolecule conformation of poly-D-glutamic acid sodium salt and RNA was studied in a chemistry laboratory of a U.S. university by monitoring the change of circular dichroism (CD) spectra with a 62DS spectropolarimeter.
It is our assumption that the effect of external Qi on the basic structure of biomolecule is most like on the level of conformation, while the change in the conformation of biomolecule may cause a series of change in the life object or life phenomenon.
First, the Qigong master needs to learn what is the biomolecule conformation and also to understand how to emit External Qi to biomolecule to make change in its conformation.
www.wishus.org /research.asp?cat=research&index=10   (2309 words)

  
 A Simple and Direct Biomolecule Detection Based on a Microwave Resonator
We report a simple and direct biomolecule detection method, sensitivity enhancing technique, and its characterization realized by using a CPW-to-slotline ring resonator whose resonant frequency is 3.4 GHz.
When a biomolecule is attached on the resonator, it directly detects a biomolecule through its resonant frequency change without an additional transduction procedure.
This event is not open to the general public and NSTI reserves the right to refuse admission and participation to any individual.
nsti.org /Nanotech2006/showabstract.html?absno=346   (364 words)

  
 Scientists uncover speedometer for crystal growth controlled by biomolecule properties
The new insights predict the growth enhancing abilities of amino acids, peptide chains and also explain recent reports of very large growth enhancing effects by natural proteins extracted from the shells of abalone.
Their findings add to intrigue of how proteins and other biomolecules rearrange local water to affect many different aspects of biological systems.
Dove and her research group study the interface between minerals, waters, and biomolecules in biomineralization, cementation, chemical weathering, paleoproxy models, metal and biomolecule binding.
www.eurekalert.org /pub_releases/2006-12/vt-sus112906.php   (664 words)

  
 [No title]
A biomolecule is a dependent biostructure which consists of a single molecule.
The study of biomolecules as Physical Agents is the subject matter of biochemistry, part of chemistry.
The study of biomolecules in their role as dependent biostructures is the subject matter of molecular biology, part of biology.
www36.pair.com /waldzell/Library/Inventory/Liv/Biomolecule.html   (147 words)

  
 News - PHOTOPROTECTIVE EFFECT MEASURED AT SINGLE BIOMOLECULE LEVEL
During photoprotection, the consensus school of thought was that carotenoids - the source of the orange pigments in carrots and Vitamin A - become oxidized, or charged, losing an electron in the process.
To get at the heart of the problem, Fisher had to attempt an experiment that had never been done before for any biomolecule: to control the charge of the biomolecule while measuring its ability to hold a current.
By holding a carotenoid under potential control, Fisher could control whether the biomolecule was in a neutral state or in the charged state (the oxidized state), while simultaneously measuring the electron transport through a single molecule.
www.scientistlive.com /15774/photoprotective-effect-measured-at-single-biomolecule-level.thtml   (958 words)

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