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| | David Atkinson, Ph.D., Physiology & Biophysics at Boston University School of Medicine |
 | | The emphasis is on the analysis of the organization of apo-B and the localization of structural and functional domains on the LDL particle, using a combination of site-specific immuno-nanogold labeling and direct visualization of the bound LDL receptor. |
 | | These include protein crystallography, structural electron microscopy/image processing, calorimetry/thermodymamics, circular dichroism, and molecular modelling/mechanics to probe the structure and physical properties of lipoproteins, apolipoproteins, peptide models for the apolipoproteins, and lipid/apolipoprotein reassembled model systems. |
 | | This advanced course covers the concepts of the assembly of biomacromolecules, their structure and stabilizing forces, and biological function as related to structure. |
| biophysics.bumc.bu.edu /faculty/atkinson (1757 words) |
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