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Topic: Bismuth subsalicylate


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In the News (Sat 11 Oct 08)

  
  Disease Listing, Travelers' Diarrhea, General Information | CDC Bacterial, Mycotic Diseases
Studies show a decrease in the incidence of TD with use of bismuth subsalicylate and with use of antimicrobial chemoprophylaxis.
Use of bismuth subsalicylate should be avoided by persons who are allergic to aspirin, during pregnancy, and by persons taking certain other medications (e.g., anticoagulants, probenecid, or methotrexate).
Bismuth subsalicylate also may be used as treatment: 1 fluid ounce or 2 262 mg tablets every 30 minutes for up to eight doses in a 24-hour period, which can be repeated on a second day.
www.cdc.gov /ncidod/dbmd/diseaseinfo/travelersdiarrhea_g.htm   (1182 words)

  
  The Nitrogen Family: BISMUTH!!
Bismuth is a relatively rare metal found in the earth's crust at about the same abundance as silver and almost never occurring in the native state.
Bismuth is found free in nature and in such ores as bismuth glance and bismite which are primarily found in South America but are rare in the United States.
Bismuth is used in a wide variety of pigments ranging from cosmetics to the coloration of glass, decorative glazing, enameling and "metallic" automotive paints, as well as UV or heat-absorbing coatings for outer-space and strategic applications.
www.carondelet.pvt.k12.ca.us /Family/Science/Nitrogen/bismuth.html   (511 words)

  
 Bismuth (UK PID)
Bismuth subnitrate and carbonate are used in surgical dressings and bismuth chelate (tripotassium dicitratobismuthate) is used in the treatment of gastric and duodenal ulcers.
Toxicity Bismuth toxicity is associated primarily with exposure to bismuth salts, notably the ingestion of bismuth chelate.
Bismuth subsalicylate toxicity as a cause of prolonged encephalopathy with myoclonus.
www.intox.org /databank/documents/chemical/bismuth/ukpid49.htm   (5516 words)

  
 bismuth subsalicylate, metronidazole, and tetracycline - [Medication]
Bismuth subsalicylate, metronidazole, and tetracycline is not approved for use by children.
Together, bismuth subsalicylate, metronidazole, and tetracycline are used to treat Helicobacter pylori, a bacterial infection involved in causing stomach ulcers.
Bismuth subsalicylate, metronidazole, and tetracycline is in the FDA pregnancy category D. This means that it is known to harm an unborn baby.
www.peacehealth.org /kbase/multum/d04061a1.htm   (1371 words)

  
 C&EN: IT'S ELEMENTAL: THE PERIODIC TABLE - BISMUTH   (Site not responding. Last check: )
It is mined as bismuth oxide (Bi, also known as bismite) or bismuth sulfide (Bi, bismuthinite), and the brittle, silvery elemental form is one of a few substances (water is another) for which the solid is less dense than the liquid.
The binding of bismuth to proteins of exposed ulcer tissue and the formation of a protective coating is proposed as a mode of action for the ulcer-healing behavior of some bismuth compounds.
The indisputable antimicrobial activity of various bismuth compounds at appropriate concentrations, the relatively low elemental human-cell cytotoxicity, and the apparent gastric cytoprotective properties of certain bismuth salts highlight the chemistry of bismuth as an important focus for the development or discovery of new gastrointestinal pharmaceutical agents.
pubs.acs.org /cen/80th/bismuth.html   (697 words)

  
 Bismuth Summary
Bismuth is a soft, silvery metal with a bright, shiny surface and a yellowish or pinkish tinge.
Bismuth oxychloride is extensively used in cosmetics and bismuth subnitrate and subcarbonate are used in medicine.
Bismuth subsalicylate (Pepto-BismolĀ®) is used as an antidiarrheal.
www.bookrags.com /Bismuth   (3176 words)

  
 Patient Education - Drugs - bismuth
Subsalicylate is a non-aspirin salicylate which means it is related to aspirin.
Bismuth may cause a temporary and harmless darkening of the tongue and stool.
Bismuth is a mild antidiarrheal agent for temporary diarrhea.
www.gicare.com /pated/bismuth.htm   (765 words)

  
 FR Doc 05-154
FDA proposed bismuth subsalicylate as safe and effective for the relief of symptoms of upset stomach associated with overindulgence in food and drink in the TFM, and simethicone is included in the antiflatulent monograph (21 CFR part 332).
Bismuth subsalicylate acts in the stomach to relieve upset stomach/indigestion symptoms such as nausea, heartburn, and fullness, while simethicone acts in the stomach to break up gas bubbles resulting from overindulgence in food and drink.
Bismuth subsalicylate is not included in the antacid monograph but based on the information and analysis in this document has an antigas (antiflatulent) effect when relieving symptoms of overindulgence in food and drink.
www.fda.gov /OHRMS/DOCKETS/98fr/05-154.htm   (3814 words)

  
 Bismuth Subsalicylate
It is believed that the parent compound is cleaved in the small intestine into bismuth carbonate and salicylate.
In humans, the amount of bismuth absorbed is negligible while the salicylate component is rapidly and completely absorbed.
As bismuth is radiopaque, it may interfere with GI tract radiologic examinations.
www.elephantcare.org /Drugs/bismuths.htm   (691 words)

  
 Bismuth Subsalicylate Drug Information, Professional
—Bismuth subsalicylate is used, in combination with oral antibiotic therapy, in the treatment of Helicobacter pylori –associated gastritis and duodenal ulcer.
Bismuth subsalicylate may exert its antidiarrheal action not only by stimulating absorption of fluid and electrolytes across the intestinal wall (antisecretory action) but also, when hydrolyzed to salicylic acid, by inhibiting synthesis of a prostaglandin responsible for intestinal inflammation and hypermotility.
Note: Although significant interactions are unlikely with usual doses of bismuth subsalicylate in the treatment of diarrhea and for occasional relief of gastric distress, the higher doses and the longer therapy used in the prophylaxis of traveler's diarrhea increase the potential for significant drug interactions.
www.drugs.com /mmx/bismuth-subsalicylate.html   (3266 words)

  
 Patient Education - Drugs - bismuth
This bismuth preparation is used primarily to treat diarrhea.
Because bismuth may interfere with x-ray examinations of the GI tract, it should not be taken for several days before an abdominal x-ray exam.
Bismuth is not recommended long-term as an antacid since there are much more effective antacids and, especially, drugs to reduce stomach acid.
www.endowsec.com /pated/bismuth.htm   (747 words)

  
 Dr. William K. Summers - Bismuth Toxicity Masquerading as Alzheimer's Dimentia
An elevated serum bismuth level of 242 ug/L (normal is 5 ug/L) established bismuth toxicity as the cause of the dementia.
Bismuth preparations are generally considered very safe and are often taken without knowledge of possible, albeit rare, neurotoxicity.
Bismuth toxicity typically presents subacutely with mental changes of memory loss, psychosis and depression, with a prominent background of ataxia, tremors, myoclonus and seizures (4).
www.alzcorp.com /article5.html   (1007 words)

  
 Bismuth Minerals,Bismuthinite,Bismite,Bismuth Information,Bismuth Uses,Bismuth Suppliers
Bismuth produced in the United States is obtained as a by-product of copper, gold, silver, tin and especially lead ore processing.
Bismuth, a silvery-white metallic element was long thought to be a variety of lead or tin due to its resemblance.
Native bismuth is rare and does not occur in large quantities.
www.mineralszone.com /minerals/bismuth.html   (389 words)

  
 MedlinePlus Drug Information: Bismuth Subsalicylate
Bismuth subsalicylate is used to treat diarrhea, heartburn, and upset stomach in adults and children 12 years of age and older.
Bismuth subsalicylate comes as a liquid, tablet, or chewable tablet to be taken by mouth, with or without food.
If you will be giving bismuth subsalcylate to a child or teenager, tell the child's doctor if the child has any of the following symptoms before he or she receives the medication: vomiting, listlessness, drowsiness, confusion, aggression, seizures, yellowing of the skin or eyes, weakness, or flu-like symptoms.
www.nlm.nih.gov /medlineplus/druginfo/medmaster/a607040.html   (811 words)

  
 Bismuth Subsalicylate, Metronidazole, and Tetracycline—For H. pylori(Systemic) - [Medication]
Bismuth subsalicylate BIS-muth sub-sa-LIS-a-late, metronidazole me-troe-NI-da-zole, and tetracycline tet-ra-SYE-kleen are taken together with a histamine H
There is no specific information comparing the use of this combination of medicines (bismuth subsalicylate, metronidazole, and tetracycline) in the elderly with its use in other age groups.
Each dose of this combination of medicines (bismuth subsalicylate, metronidazole, and tetracycline) is taken four times a day, with meals and at bedtime, for fourteen days.
www.luhs.org /health/kbase/htm/mdx-/drde/2036/33/mdx-drde203633.htm   (1952 words)

  
 Bismuth Subsalicylate of No Use in Acute Diarrhea
A placebo-controlled, randomized trial evaluated the effect of bismuth subsalicylate (100 mg/kg bismuth and 150 mg/kg bismuth q4h for up to 5 days) on the duration and volume of acute watery diarrhea in 275 males (mean age of 13.5 months).
Patients receiving bismuth had reduction in their stool output by about 30% (P=0.015) and a reduction of total intake of oral rehydration solution by about 25% (P=0.013) when compared to the placebo group.
Bismuth subsalicylate in the treatment of acute diarrhea in children: a clinical study.
www.med.umich.edu /pediatrics/ebm/cats/subsalic.htm   (480 words)

  
 Bismuth Subsalicylate (Oral) - MayoClinic.com
It was reformulated to contain bismuth subsalicylate as the active ingredient.
Bismuth subsalicylate (BIS-muth sub-sa-LIS-a-late) is used to treat diarrhea in adults and teenagers.
Tetracyclines by mouth (medicine for infection)—The tablet form of bismuth subsalicylate should be taken at least 1 to 3 hours before or after tetracyclines; otherwise it may decrease the effectiveness of the tetracycline
www.mayoclinic.com /health/drug-information/DR202092   (1850 words)

  
 Victorian America -- Bismuth Powders
Bismuth subsalicylate is apparently a major ingredient in Pepto-Bismol.
Bismuth is a useful remedy for diarrhoea but is poisonous if given over too long a period.
Pregnancy—The occasional use of bismuth subsalicylate is not likely to cause problems in the fetus or in the newborn baby.
www.lizzieandrewborden.com /Archive0404/VictAmer/Bismuth.htm   (2970 words)

  
 Bismuth - Wikipedia, the free encyclopedia
While bismuth was traditionally regarded as the element with the heaviest stable isotope, it had long been thought to be unstable on theoretical grounds.
Bismuth is relatively nontoxic and has a low melting point; it can be melted with a household stove.
Bismuth subsalicylate (the active ingredient in Pepto-Bismol) is used as an antidiarrheal and to treat some other gastro-intestinal diseases.
en.wikipedia.org /wiki/Bismuth   (1147 words)

  
 NEJM -- A Controlled Trial of Bismuth Subsalicylate in Infants with Acute Watery Diarrheal Disease
Bismuth subsalicylate in the treatment of acute diarrhea in children: a clinical study.
Bismuth subsalicylate inhibits activity of crude toxins of Escherichia coli and Vibrio cholerae.
Double-blind comparison of bismuth subsalicylate and placebo in the prevention and treatment of enterotoxigenic Escherichia coli-induced diarrhea in volunteers.
content.nejm.org /cgi/content/full/328/23/1653   (3563 words)

  
 The Analyst - Internet Health Report: Treatment: Bismuth
Bismuth Subsalicylate, the most commonly encountered form of bismuth, is a mineral that is used in the treatment of upset stomach, diarrhea, or to prevent traveler's diarrhea.
It is also used in the treatment of stomach ulcer and upset stomach associated with infection due to the bacteria Helicobacter pylori.
Thirteen patients with microscopic colitis were treated with 8 chewable 262mg bismuth subsalicylate tablets per day for 8 weeks.
www.digitalnaturopath.com /treat/T438561.html   (1169 words)

  
 Page3
It is no wonder that bismuth salts have been widely used since antiquity and still hold a secure place in medicinal therapy today.
Another factor was the increased use of bismuth to treat the increasing number of colostomy patients.
The average dose of bismuth subsalicylate contained in Pepto-Bismol has a dose of of salicylate almost equal to that of an aspirin once the compound dissociates in the stomach.
www.frfoundation.org /Page3.htm   (1201 words)

  
 Bismuth
Subsalicylate should be used with caution if patient is taking aspirin; use with caution in children, especially those <3 years of age and those with viral illness; may be neurotoxic with very large doses
Subsalicylate: Hyperpnea, nausea, vomiting, tinnitus, hyperpyrexia, metabolic acidoses/respiratory alkalosis, tachycardia, and confusion; seizures in severe overdose, pulmonary or cerebral edema, respiratory failure, cardiovascular collapse, coma, and death.
Bismuth subsalicylate exhibits both antisecretory and antimicrobial action.
www.musc.edu /pharmacyservices/Drugs/B/Bismuth.htm   (767 words)

  
 Bismuth Subsalicylate (Oral)
Bismuth subsalicylate (BIS-muth sub-sa-LIS-a-late) is used to treat diarrhea.
The occasional use of bismuth subsalicylate is not likely to cause problems in the fetus or in the newborn baby.
The dose of bismuth subsalicylate will be different for different patients.
allnutritionals.com /drugs/b/bismuthsubsalicylate-oral.shtml   (1956 words)

  
 Biochemical Periodic Table - Bismuth
Bismuth is a heavy metal that is relatively non-toxic to humans in comparison to the metals and metalloids surrounding it in the periodic table (i.e.
About half of the bismuth mined each year is used in pharmaceuticals, with the remainder used in other products such as cosmetics, semiconductors, glass and ceramics, and hunting ammunition.
These "bismuth mirrors" were proposed to be composed of reduced metallic bismuth, but this has not been confirmed.
umbbd.msi.umn.edu /periodic/elements/bi.html   (421 words)

  
 BISMUTH SUBSALICYLATE - [Alternative Medicine]
Bismuth Subsalicylate is a mineral that is used in the treatment of upset stomach, diarrhea, or to prevent traveler's diarrhea.
McNulty CAM: Bismuth subsalicylate in the treatment of gastritis due to Campylobacter pylori.
Eberhardt R and Kasper G: Effect of oral bismuth subsalicylate on Campylobacter pylori and on healing and relapse rate of peptic ulcer.
www.luhs.org /health/kbase/htm/mdx-/ame0/209/mdx-ame0209.htm   (786 words)

  
 Consumer Reports Health - Bismuth Subsalicylate, Metronidazole, and Tetracycline Combination
Bismuth subsalicylate, metronidazole, and tetracycline combination is used to treat duodenal ulcers.
Bismuth subsalicylate, metronidazole, and tetracycline combination comes as four pills: two pink, round, chewable tablets (bismuth subsalicylate), one white tablet (metronidazole), and one pale orange and white capsule (tetracycline).
Bismuth subsalicylate, metronidazole, and tetracycline combination may cause side effects.
www.consumerreports.org /mg/drug-reports/bismuth-subsalicylate-metronidazole-and-tetracycline.htm   (1013 words)

  
 Antidiarrheal Medicines: OTC Relief for Diarrhea -- familydoctor.org   (Site not responding. Last check: )
Bismuth subsalicylate can also be used for upset stomach and as an antiemetic (a medicine that treats nausea and vomiting).
Bismuth subsalicylate works by balancing the way fluid moves through your bowels.
Bismuth subsalicylate may affect some drugs so that they don’t work as well.
familydoctor.org /855.xml?printxml   (840 words)

  
 Bismuth Subsalicylate
Bismuth subsalicylate is a nonprescription drug used to relieve
It is also used to control diarrhea and traveler’s diarrhea.
Sarsaparilla may increase the absorption of digitalis and bismuth, increasing the chance of toxicity.
www.maxlabs.com /hn/Drug/Bismuth_Subsalicylate.htm   (344 words)

  
 Interaction of Bismuth Subsalicylate with Fruit Juices, Ascorbic Acid, and Thiol-Containing Substrates To Produce ...   (Site not responding. Last check: )
Bismuth (III) complexes of 2-mercaptoethanol: preparation, structural and spectroscopic characterization, antibacterial activity toward Helicobacter pylori, and inhibitory effect toward H.
Definitive identification of cysteine and glutathione complexes of bismuth by mass spectrometry: assessing the biochemical fate of pharmaceutical agents.
Syntheses and structures of bismuth (III) complexes with nitrilotriacetic acid, ethylenediaminetetraacetic acid, and diethylenetriaminepentaacetic acid.
aac.asm.org /cgi/content/full/49/1/431   (1347 words)

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