| | HTA abstract20040835 (Site not responding. Last check: 2007-10-21) |
 | | Although BIS monitoring may reduce the incidence of intraoperative awareness generally for patients undergoing anesthesia, it has limited value for individual patients for the following reasons: - It is a relatively good indicator of the state of being alert, but its algorithm is inaccurate for predicting an unconscious state. |
 | | In both of the large studies that demonstrated a lower incidence of intraoperative awareness (i.e., the Bi-Aware RCT and European prospective study), the anesthesia was deep during maintenance (a mean BIS score of 44.5 [SD, 6.8]in the Bi-Aware trial, and a mean BIS score of 38 [SD, 8]in the European study). |
 | | Considering the low sensitivity of BIS monitoring to detect the state of being asleep, several patients would be at risk of receiving unnecessary hypnotic medications to save one from intraoperative awareness. |
| nhscrd.york.ac.uk /online/hta/20040835.htm (655 words) |