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Topic: Bonnie Bassler

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	IUBMB2007 - Bonnie Bassler
		Bassler, a member of the National Academy of Sciences, is a Howard Hughes Medical Investigator and Professor of Molecular Biology at Princeton University.
		Bassler is the Director of Graduate Studies in the Molecular Biology Department, and she teaches both undergraduate and graduate courses.
		Bassler is an editor for Molecular Microbiology and Annual Reviews of Genetics, and she is an associate editor for the Journal of Bacteriology.
	sbbq.iq.usp.br /iubmb2007/index.php?option=com_content&task=view&id=30 (425 words)

	Wired 11.04: The Bacteria Whisperer (Site not responding. Last check: )
		Trim and hyperkinetic at 40, Bonnie Bassler is often mistaken for a graduate student at conferences.
		Last year, Bassler and her colleagues unlocked the structure of a molecular language shared by many of nature's most fearsome particles of mass destruction, including those responsible for cholera, tuberculosis, pneumonia, septicemia, ulcers, Lyme disease, stomach cancer, and bubonic plague.
		What Bassler and other pioneers in her field have given us, however, is more than a set of potential drug targets.
	www.wired.com /wired/archive/11.04/quorum.html (1090 words)

	Bugging the Bugs
		Bassler's fascination with bacterial communication, quorum sensing, and luminescence began in 1990, while she was a graduate student.
		Bassler was cited for work that "reveals new insights into the basic biology and ecology of bacteria, findings that may have direct application in the future treatment of disease." She was awarded $500,000 over 5 years to spend any way she would like.
		Bonnie Bassler is a bacterial geneticist at Princeton University.
	publications.nigms.nih.gov /findings/oct04/bugging.html (2174 words)

	Encyclopedia: Bonnie Bassler (Site not responding. Last check: )
		Bassler later found that many bacteria employ the same signaling system and respond to each other's signals, a finding that sparked widespread interest in the subject.
		Bassler turned to Hughson, whose specialty is finding the three-dimensional structure of large, complicated protein molecules.
		It is far too early in the morning, and Bonnie L. Bassler is charging across the Princeton University campus, incandescent purple coat flying, brown curls bouncing, big laugh booming.
	www.nationmaster.com /encyclopedia/Bonnie-Bassler (365 words)

	Bonnie Bassler
		Bonnie L. Bassler is a molecular biologist at Princeton University.
		She discovered a mechanism by which bacteria communicate by chemical signalling, known as quorum sensing.
		The text of this article is licensed under the GFDL.
	www.ebroadcast.com.au /lookup/encyclopedia/bo/Bonnie_Bassler.html (53 words)

	Princeton - News - Biologist Bonnie Bassler receives MacArthur Fellowship
		Bassler's research focuses on a phenomenon called "quorum sensing," which is a method that bacteria use for sensing how many other bacteria are in their vicinity.
		Bassler has identified the genetic and biochemical mechanisms that regulate quorum sensing and also has shown that these mechanisms are common to many different kinds of bacteria.
		Bassler received a B.S. in 1984 from the University of California-Davis and a Ph.D. in 1990 from Johns Hopkins University.
	www.princeton.edu /pr/news/02/q3/0925-bassler.htm (611 words)

	Bassler discusses issues of race and science - The Daily Princetonian
		Last night, Bonnie Bassler, the University’s Squibb professor in molecular biology, discussed the American aversion to science and the need for a more racially diverse population of scientific researchers before a crowd of more than 50 students and community members in McCormick Hall 101.
		Bassler, an award-winning researcher, was this year’s speaker for the third annual James Baldwin lecture.
		Bassler went on to lament the fact that the widespread fear of science is keeping students from exploring a very interesting area of study.
	www.dailyprincetonian.com /2008/04/23/20976 (821 words)

	Bonnie Bassler - Wikipedia, the free encyclopedia
		Bonnie L. Bassler is a molecular biologist professor at Princeton University.
		She made key insights into the mechanism by which bacteria communicate, known as quorum sensing.
		Bassler's Research review titled "The languages of bacteria" (GENES and DEVELOPMENT June 15, 2001)
	en.wikipedia.org /wiki/Bonnie_Bassler (103 words)

	loneknight.org - articles and other written works
		Trim and hyperkinetic at 40, Bonnie Bassler is often mistaken for a graduate student at conferences.
		Bassler determined that what looked like one signaling system was actually two: The first sensed the presence of other V. harveyi cells, and the second received signals from many other kinds of bacteria.
		But in part because Bassler's cute glow-in-the dark microbes seemed to have little impact on the health or commercial success of humankind, her discoveries were considered a sideline curiosity in the world of mainstream science.
	www.loneknight.org /articles.asp?article=25 (2512 words)

	MStoneWorks.Net - Microbiology - Microbial Chatter: How Bacteria Talk With One Another
		Bacteria chatter continuously and their words are chemical, continued Bassler, proving her point by describing some recently translated bacterial languages in a communication system called “quorum sensing,” which consists of the production, release, and subsequent detection of and response to threshold concentrations of small signaling molecules called autoinducers (AIs).
		Bassler, who was elected to the National Academy of Sciences in 2006, is a Howard Hughes Medical Investigator and Professor of Molecular Biology at Princeton University.
		Bassler performed her postdoctoral work in genetics at the Agouron Institute, and joined the Princeton faculty in 1994 where she is the Director of Graduate Studies in the Department of Molecular Biology.
	mstoneworks.net /InfectiousDisease/MicrobialChatter.htm (4276 words)

	bonnie - Hutchinson encyclopedia article about bonnie
		Town and port in Cross Rivers State, Nigeria, situated in the southeast of the Niger delta, 40 km/25 mi downstream from Port Harcourt, on the Bonny River.
		Bonny was associated with the slave trade in the 18th and 19th centuries.
		This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.
	encyclopedia.farlex.com /bonnie (111 words)

	BiofilmsONLINE.com : News : Small Talk--The Gabfest of Microbial Communication
		But don't snicker…ONR-sponsored Bonnie Bassler won a MacArthur Foundation 'genius award' last year for her research on how some of the most deadly microbes we know – cholera, plague, TB, just to mention a few – communicate surprisingly well.
		Bassler's research is important in the fight against virulent strains of bacteria.
		Bassler and colleagues recently showed that cholera bacteria use quorum sensing to regulate their virulence.
	www.biofilmsonline.com /cgi-bin/biofilmsonline/00140.html (616 words)

	Bacteria Make Sense
		The 41-year-old Bassler - a professor of molecular biology, winner of a 2002 MacArthur Foundation genius award, and occasional actress, dancer and singer - studies bacteria and how they communicate among their own kind and with other species.
		Bacteria "don't have enough room in their genome to be stupid, so there had to be a separate purpose for this system." The foreign bacteria were emitting something that V harveyi responded to.
		Bassler's drive - her friend and former mentor Silverman describes her as "intensely motivated," "on a quest" and "just fierce" - suggests that she will hear bacteria's every last word.
	flatrock.org.nz /topics/science/talking_bacteria.htm (4507 words)

	Newswise
		Bassler found this molecular signal after years of studying certain luminescent bacteria that are widespread in oceans but are harmless to people.
		She used these mutants to show that one system tells the bacteria how many of its own species are in the area; the other tells how many other types of bacteria are around.
		When she came to Princeton four years ago, Bassler herself would have never guessed she would be working with E. coli and Salmonella.
	www.newswise.com /articles/view?id=BASSLER.PTU (943 words)

	Small talk--The gabfest of microbial communication
		In her Princeton Lab, Bassler (and the rest of the microbiology community) calls it 'quorum sensing.' When microbes sense that there's more than just a few of them around (i.e., increases in cell population density), a sort of gabfest starts, and this can lead to the production of toxins that make us very, very sick.
		Bassler's research is important in the fight against virulent strains of bacteria.
		Bassler and colleagues recently showed that cholera bacteria use quorum sensing to regulate their virulence.
	www.eurekalert.org /pub_releases/2003-04/oonr-stg042903.php (612 words)

	Leisure Agency News: Diplomacy Begins in the Bloodstream
		The discovery, spearheaded by Bonnie Bassler of Princeton University, was heralded by scientific genius and Presidential candidate Bili Rubin as "a great step forward in human-microbe relations," since it will pave the way for the concept that bacteria currently thought of as dangerous and unredeemable can respond to negotiation.
		Bassler's research in the phenomenon of bacterial communication, known as quorum sensing, has opened up the possibility of non-violent methods of protecting humans from illness:
		Bonnie Bassler is to be saluted for her research, which highlights the fact that "hit them with everything we've got" is not always the best way to deal with adversaries.
	leisureagency.org /news/archives/000305.html (240 words)

	Quorum sensing - Wikiversity
		Quorum sensing, first observed by Princeton Microbiologist, Bonnie Bassler is the ability of bacteria to communicate and coordinate their behavior through signaling molecules.
		Her pioneering work began as an intense study of the bioluminiscent properties of the somewhat benign Vibrio fischeri bacteria found in the light-producing organ of the Hawaiian bobtail squid (Euprymna scolopes).
		Bassler, now a professor at Princeton's Department of Molecular Biology is directing her team toward a study of the general phenomenology of
	en.wikiversity.org /wiki/Quorum_sensing (262 words)

	Dialogs With Bacteria: Quorum Sensing
		This new branch of microbiology, quorum sensing, discovered by Bonny Bassler, professor of microbiology from Princeton, is dedicated to studying this phenomenon.
		Professor Bassler discovered that bacteria could send signals not only to their own kind, but to other bacteria as well.
		Miller, M.B. and Bassler, B.L. Quorum sensing in bacteria.
	library.albany.edu /science/whatsnew_dialogs.htm (2947 words)

	BiofilmsONLINE.com : News : Say What? Bacterial Conversation Stoppers
		The interspecies crosstalk and misdirection could have important consequences for human health, said Bonnie L. Bassler, an HHMI investigator at Princeton University whose study was published in the September 29, 2005, issue of Nature.
		A chemical signal called autoinducer-2 (AI-2), originating from the same gene in all bacteria, is released outside the cell to announce the cell's presence.
		Researchers have speculated that AI-2 is a universal language, and the new study from Bassler's lab is the first to show those conversations taking place – and producing consequences -- between co-mingling species.
	www.biofilmsonline.com /cgi-bin/biofilmsonline/00328.html (660 words)

	HHMI News: Bonnie L. Bassler, Ph.D.
		HHMI News: Bonnie L. Bassler, Ph.D. Bonnie L. Bassler, Ph.D. Until recently, the ability of bacteria to communicate with one another was considered an anomaly that occurred only among a few marine bacteria.
		Bassler showed that a gene called luxS is required for production of AI-2, and that hundreds of species of bacteria have this gene and use AI-2 to communicate.
		Bonnie L. Bassler earned a B.S. in biochemistry at the University of California, Davis, and a Ph.D. in biochemistry at The Johns Hopkins University.
	www.hhmi.org /news/bassler.html (545 words)

	A Biologist's Listening Guide to Bacteria : NPR
		Bonnie Bassler is a member of the august National Academy of Sciences, a MacArthur genius award recipient, and runs a well-funded lab at Princeton University.
		Bonnie Bassler's discovery about how bacteria talk to one another has led to a whole new field of research -- and maybe someday drugs that would be effective against all bacteria.
		"Bonnie's a lot of fun and she makes the time go very quickly, though we're huffing and puffing and getting a good workout," says Kathie Wilcox, who has been coming to Bassler's class for the past five years.
	www.npr.org /templates/story/story.php?storyId=6061852 (1796 words)

	Stopping Superbugs: Science Videos - Science News - ScienCentral
		In Bonnie Bassler's lab at Princeton University, researchers use bioluminescence to reveal when bacteria are talking to each other and what they're saying.
		Bassler explains her strategy, "We want to make molecules that jam the receptors, that make the bacteria unable to 'talk,' or unable to 'hear.'"
		But Bassler says their technique could be used to one day develop new types of antibiotics.
	www.sciencentral.com /articles/view.php3?type=article&article_id=218393033 (793 words)

	Princeton’s Bonnie Bassler to Give Jordy Lecture -- University News -- Drew University
		Bonnie Bassler, professor of molecular biology at Princeton and recipient of a MacArthur Grant, will deliver the 2004 Jordy Research Scholar Lecture at Drew University on September 28, at 4:15 p.m.
		The topic of Dr. Bassler’s talk is "Tiny Conspiracies: Cell-to-Cell Communication in Bacteria." Her research focuses on a phenomenon called "quorum sensing" which is a method bacteria use to sense how many other bacteria are in their vicinity.
		Quorum sensing is important in determining the virulence of bacteria under a specific set of circumstances.
	www.depts.drew.edu /media/news/article.php?id=270 (157 words)

	Bonnie Bassler - Encyclopedia, History, Geography and Biography (Site not responding. Last check: )
		Bonnie Bassler - Encyclopedia, History, Geography and Biography
		This encyclopedia, history, geography and biography article about Bonnie Bassler contains research on
		Bonnie Bassler, External link, MacArthur Fellows and Molecular biology.
	www.arikah.com /encyclopedia/Bonnie_Bassler (114 words)

	Princeton scientists break cholera's lines of communication
		Her team has shown that the chemical also can be used to disrupt the communication that exists among the bacteria, potentially halting the disease's progress.
		Quorum sensing, which Bassler's lab has explored for more than a decade, concerns the ability of single-celled bacteria to perceive that they are surrounded by a dense population of other bacteria.
		Bassler's team realized that the cholera must be signaling each other with some unknown chemical when the time was right to stop reproducing and exit the body.
	www.eurekalert.org /pub_releases/2007-11/pu-psb111407.php (1089 words)

	NOVA \| scienceNOW \| Profile: Bonnie Bassler: Bacteria Talk \| PBS
		Bassler and her students helped turn a harmless, bioluminescent bacterium into a star of scientific research—a model organism holding lessons about how all bacteria communicate.
		Bassler: In my lab, we are always thinking about how cells, bacterial cells, can talk to each other and then organize themselves into enormous groups that function in unison.
		Bassler: What's become clear in the last decade is that all bacteria talk to each other.
	www.pbs.org /wgbh/nova/sciencenow/3401/04-bact.html (2791 words)

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