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Topic: Bornaviridae


In the News (Mon 28 Dec 09)

  
  Borna disease - Wikipedia, the free encyclopedia
The causative agent of Borna disease, Borna disease virus (BDV) is a neurotropic virus and is the sole member of the Bornaviridae family within the Mononegavirales order.
It has the smallest genome (8.9 kilobases) of any Mononegavirales species and is unique within that order in its ability to replicate within the host cell nucleus.
A new family named the bornaviridae was created to hold this virus.
en.wikipedia.org /wiki/Borna_disease   (817 words)

  
 Borna disease Neurology
The causative agent of Borna disease, Borna disease virus (BDV) is a neurotropicvirusand is the sole member of the Bornaviridae family within the Mononegavirales order.
It has the smallest genome(8.9 kilobases) of any Mononegavirales species and is unique within that order in its ability to replicate within the host cell nucleus.
Borna virus appears to have a wide host range, having been detected in horses, cattle, sheep, dogsand foxes.
www.lumrix.com /medical/neurology/borna_disease.html   (705 words)

  
 Medscape MEDLINE search: Bornaviridae
Borna disease virus-specific circulating immune complexes, antigenemia, and free antibodies--the key marker triplet determining infection and prevailing in severe mood disorders.
Borna disease virus (BDV), a unique genetically highly conserved RNA virus (Bornaviridae; Mononegavirales), preferentially targets neurons of limbic structures causing behavioral abnormalities in animals.
Borna disease virus (BDV) is an enveloped, non-segmented negative-stranded RNA virus which belongs to the Bornaviridae family.
search.medscape.com /uslclient/searchMedline.do?queryText=Bornaviridae   (838 words)

  
 Mononegavirales Terms and Definitions at www.MedicalGlossary.org
The families are BORNAVIRIDAE; FILOVIRIDAE; PARAMYXOVIRIDAE; and RHABDOVIRIDAE.
Bornaviridae - A family in the order MONONEGAVIRALES comprising one genus Bornavirus.
This family has a unique form of mRNA processing: replication and transcription takes place in the nucleus.
www.medicalglossary.org /rna_viruses_mononegavirales_definitions.html   (243 words)

  
 Eingang zum Volltext
Das Borna Disease Virus (BDV, Bornavirus) besitzt ein einzelsträngiges RNA-Genom negativer Polarität und ist innerhalb der Ordnung Mononegavirales der Prototyp einer eigenen Virusfamilie, die der Bornaviridae.
Eine außergewöhnliche Eigenschaft des Virus ist seine nukleäre Transkription und Replikation, eine weitere besteht in seiner Fähigkeit, als neurotropes Virus sowohl in vivo als auch in vitro persistente Infektionen zu etablieren.
Within the order of Mononegavirales it is the prototype of a new virus family named Bornaviridae.
opus.kobv.de /ubp/frontdoor.php?source_opus=690   (746 words)

  
 EID V3 N2: Borna Disease
Although Borna disease was first recognized in the early 1800s as a neurologic syndrome with an infectious basis, Borna disease virus (BDV) has only recently been characterized as the causative agent.
BDV is the prototype of a newly recognized virus family, Bornaviridae, within the nonsegmented negative-strand RNA viruses (order Mononegavirales) (1,2).
The molecular biology of the virus has several unusual aspects, including nuclear localization for replication and transcription (3), overlap of open reading frames and transcription units (4,5), posttranscriptional modification of subgenomic RNAs (6,7), and marked conservation of coding sequence across various animal species and tissue culture systems (8,9).
www.cdc.gov /ncidod/EID/vol3no2/hatalski.htm   (3726 words)

  
 [No title]   (Site not responding. Last check: 2007-10-29)
Persistent viral infections of the central nervous system have been the subject of intense interest for decades.
One of these viral agents has been identified as Borna disease virus (BDV) of the family Bornaviridae.
There have been various reports that link BDV to staggering disease in cats, with symptoms that include ataxia and behavioural disorders, and the disease is often referred to as feline Borna disease.
www.euroscience.nl /2006-25a.html   (128 words)

  
 [No title]
The minus-sense RNA viruses can be divided into two groups: those with nonsegmented and those with segmented genomes.
The Rhabdo-, Paramyxo-, Filo-, and Bornaviridae families belong to the former grouping and the Orthomyxo- and Bunyaviridae families belong to the latter grouping.
Because of the fact that the genomes of minus-sense RNA viruses cannot be translated into virus-specific proteins, the first order of business of a minus-sense RNA virus upon entry into the cell cytoplasm is to synthesis mRNA.
www2.gsu.edu /~biotkf/bio475/475lecture6.htm   (2044 words)

  
 [No title]   (Site not responding. Last check: 2007-10-29)
Date sent: Wed, 17 Nov 1999 Borna Disease Virus Proteins in Patients with CFS J Chronic Fatigue Syndrome; 5, No. 3/4, 1999 Susan Levine, MD Susan Levine, Beth Israel Hospital, NYC, 889 Lexington Avenue, NYC 10021 SUMMARY.
Bornavirus is a member of a newly recognized virus family, Bornaviridae, and is neurotropic for a wide range of animal species, including birds, rodents, horses, and humans.
Although little is known about its mode of transmission and it has not been clearly linked to any human disease, an association between bornaviruses and neuropsychiatric disorders has been suggested.
www.cfids-cab.org /cfs-inform/Virus/levine99.txt   (235 words)

  
 JGV Direct - BDV reverse genetics (M. Perez and others)   (Site not responding. Last check: 2007-10-29)
Its non-segmented, negative-stranded RNA genome has the coding capability for six main polypeptides and has an organization characteristic of members of the order Mononegavirales.
However, based on its unique genetics and biological features, BDV is considered to be the prototypic member of a new virus family, Bornaviridae.
Here, the establishment of a reverse genetics system for BDV is described.
www.socgenmicrobiol.org.uk /jgvdirect/19467/19467a.htm   (242 words)

  
 Borna Virus and Psychiatric Disorders
bodel@rki.de Borna disease virus (BDV), a unique genetically highly conserved RNA virus (Bornaviridae; Mononegavirales), preferentially targets neurons of limbic structures causing behavioral abnormalities in animals.
Markers and virus in patients with affective disorders and schizophrenia have raised worldwide interest.
Borna disease virus (BDV) is the prototype genus of a new family, Bornaviridae, within the order Mononegavirales.
www.psycom.net /borna.html   (2715 words)

  
 Borna Virus in Psychiatric Patients -- Neurotransmitter.net
Bode L, Reckwald P, Severus WE, Stoyloff R, Ferszt R, Dietrich DE, Ludwig H. Borna disease virus-specific circulating immune complexes, antigenemia, and free antibodies--the key marker triplet determining infection and prevailing in severe mood disorders.
BDV is an enveloped virus, non-segmented, negative-stranded RNA genome and has an organization characteristic of a member of Bornaviridae in the order of Mononegavirale.
In the present work we investigated the presence of BDV p24 RNA in peripheral blood cells from 30 psychiatric patients (19 with mood disorder and 11 with psychotic disorder) and 30 healthy volunteers as the control group.
www.neurotransmitter.net /bornavirus.html   (14166 words)

  
 VirGen   Release 1   (Site not responding. Last check: 2007-10-29)
The latest release of the database has been made available on the Centre's website on April 5, 2004.
, Bornaviridae and Filoviridae having-ssRNA genome and Narnaviridae with naked RNA genome have been added to VirGen in its latest release v1.4.
With this the total number of annotated and curated families in VirGen goes up to 15 and the number of complete genomes to 1158.
202.41.70.1 /news1.htm   (147 words)

  
 Evidence of Borna disease virus genome detection in French domestic animals and in foxes (Vulpes vulpes) -- Dauphin et ...
RNA virus which belongs to the Bornaviridae family.
Bornaviridae, within the order Mononegavirales (Lipkin et al.
BDV replicates at lower levels than most known viruses
vir.sgmjournals.org /cgi/content/full/82/9/2199   (3140 words)

  
 Bornavirus
Bornavirus, or Borna disease virus (BDV), infects a wide variety of vertebrates and belongs to the family Bornaviridae, part of the order Mononegavirales.
Bornavirus particles are enveloped, spherical structures with a diameter of 100-130 nm.
Search MEDLINE for the latest publications on this topic
www-micro.msb.le.ac.uk /3035/Bornavirus.html   (1250 words)

  
 Tamar Berger's Bornaviridae Site
The enveloped viron appears spherical and contains a helical capsid.
Bornaviridae is classified in the order Mononegavirilies, but unlike other families of this order BDV replicates in the host nucleus and has overlapping transcriptional units, some of which undergo splicing by the cellular machinery.
BDV has three transcriptional units and at least six proteins listed below:
www.stanford.edu /group/virus/borna/2005   (148 words)

  
 Cytokiny a onemocnění příštítných tělísek  Cytokines in Parathyroid Gland Diseases  Jaromír Astl1
Borna disease virus je RNA virus z čeledi Bornaviridae, řádu Mononegavirales, který je znám jako původce onemocnění teplokrevných živočichů.
We must mention infections od Borna disease virus, EBV, CMV, herpetic viruses, HIV etc.
Borna disease virus is a RNA virus represents the family Bornaviridae in the order Mononegavirales which is known as an animal pathogen.
www.tigis.cz /PSYCHIAT/psychsupp203/13.htm   (13168 words)

  
 Enhanced Neurovirulence of Borna Disease Virus Variants Associated with Nucleotide Changes in the Glycoprotein and L ...
RNA virus (6) belonging to the family Bornaviridae (13, 46).
BDV infection in experimental animals has been used to study
in the nucleus, a characteristic of Bornaviridae that is unique
jvi.asm.org /cgi/content/full/76/17/8650   (5948 words)

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