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Topic: Bradykinin


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  Migraine & Bradykinin
Bradykinin is vasoactive, meaning it acts to alter the physiological state, especially the tone and calibre, of a vessel.
The enzyme facilitates the production of bradykinin, a nonapeptide, from the precursor prekallikrein, which is found the plasma in an inactive form of the precursor of kallikrein.
This whole process is often activated by a blood factor, the Hageman factor; factor XII of the clotting process, which is the main mechanism in the setting in of inflammation when there is exposure to negative surfaces such as those found on collagen and basement membrane that are often exposed in injury.
homepage.ntlworld.com /javine/corinne/bradykinin/index.htm   (203 words)

  
  Bradykinin - Wikipedia, the free encyclopedia
Bradykinin is a physiologically and pharmacologically active peptide of the kinin group of proteins, consisting of nine amino acids.
Bradykinin is a potent endothelium-dependent vasodilator, causes contraction of non-vascular smooth muscle, increases vascular permeability and also is involved in the mechanism of pain.
Bradykinin was to prove a new autopharmacological principle, i.e., a substance that is released in the body by a metabolic modification from precursors, which are pharmacologically active.
en.wikipedia.org /wiki/Bradykinin   (516 words)

  
 NationMaster - Encyclopedia: Bradykinin
H]bradykinin and 1 mg of unlabeled bradykinin was administered.
infusion with 1 mg of bradykinin and 50 µCi [
Ferreira SH and Vane JR (1967) The disappearance of bradykinin and eledoisin in the circulation and vascular beds of the cat.
www.nationmaster.com /encyclopedia/Bradykinin   (2042 words)

  
 A SOTE Doktori Iskolájának honlapja - Védés
Ezt a hatást kísérleteinkben nem sikerült megakadályozni a bradykinin B2 receptorok gátlásával, tehát a peptid felhalmozódása nem felelős a renális hatásokért.
Hasonló szerepet a bradykinin esetében nem tudtunk igazolni, ugyanis a B2 receptorok gátlása nem befolyásolta a hypoxiás vazokonstrikciót.
Bradykinin is, however, not involved in the maintenance of neonatal blood pressure and diuresis.
phd.sote.hu /x-Vedesek/vedestoth.html   (674 words)

  
 Society of Cardiovascular Anesthesiologists
Recent investigations indicate that bradykinin pretreatment of the heart may be an important addition to standard methods of myocardial protection and that it plays an essential role in the preservation of myocardial structure and function.
They found that pretreating the heart with bradykinin prior to warm cardioplegic ischemia significantly improved postischemic ventricular function, an effect that was prevented by giving a drug that inhibits protein tyrosine kinase.
Bradykinin, by exerting a multitude of beneficial cardiovascular effects, may prove to be an important new pharmacologic adjunct to clinically improve myocardial protection in the clinical setting.
www.scahq.org /sca3/newsletters/dec_bradykinin.shtml   (584 words)

  
 NationMaster - Encyclopedia: Wilson Teixeira Beraldo
July 28, 1998, Belo Horizonte, Minas Gerais) was a Brazilian physician and physiologist, a co-discoverer of bradykinin.
Oxytocin is a nine amino acid peptide hormone synthesized in magnocellular neurosecretory cells in the hypothalamus and released by the posterior lobe of the pituitary gland.
Bradykinin was discovered by three Brazilian physiologists and pharmacologists working at the Instituto de Biologia de São Paulo, in São Paulo city, led by Dr.
www.nationmaster.com /encyclopedia/Wilson-Teixeira-Beraldo   (858 words)

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