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Migraine & Bradykinin |
 | | Bradykinin is vasoactive, meaning it acts to alter the physiological state, especially the tone and calibre, of a vessel. |
 | | The enzyme facilitates the production of bradykinin, a nonapeptide, from the precursor prekallikrein, which is found the plasma in an inactive form of the precursor of kallikrein. |
 | | This whole process is often activated by a blood factor, the Hageman factor; factor XII of the clotting process, which is the main mechanism in the setting in of inflammation when there is exposure to negative surfaces such as those found on collagen and basement membrane that are often exposed in injury. |
| homepage.ntlworld.com /javine/corinne/bradykinin/index.htm (203 words) |
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