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	Bromelain
		Bromelain is useful in the treatment of a wide range of conditions, but it is particularly effective in relieving inflammation associated with infection and physical injuries.
		Some studies of animals indicate that bromelain (applied to the surface of the skin) may be useful in removing dead tissue from third-degree burns (particularly burns that go through all layers of the skin).
		Bromelain is approved by the German Commission E for the treatment of sinus and nasal swelling following ear, nose, and throat surgery or trauma.
	www.umm.edu /altmed/articles/bromelain-000289.htm (1343 words)

	Bromelain - Wikipedia, the free encyclopedia
		Bromelain is present in all parts of the pineapple plant (Ananas comosus) but the stem is the most common commercial source, presumably because it readily available after the fruit has been harvested.
		Bromelain is sold in a powdered form, which is combined with a marinade or directly sprinkled on the uncooked meat.
		Bromelain is prepared from the stump or root portion of the pineapple plant after harvest of the fruit.
	en.wikipedia.org /wiki/Bromelain (587 words)

	Diagnose-Me: Treatment: Bromelain
		Bromelain is a general name for a family of sulfhydryl-containing, proteolytic enzymes obtained from the pineapple plant.
		Bromelain is absorbed intact through the gastrointestinal tract, with the highest concentration of bromelain being found in the blood one hour after administration.
		In an extensive study of the effect of bromelain on the stomach lining, it was found that bromelain increased the uptake of sulfur by 50% and glucosamine by 30-90%.
	www.diagnose-me.com /treat/T195469.html (2146 words)

	Bromelain
		Bromelain is a digestive enzyme that is extracted from the stem and fruit of pineapple.
		It is proposed that bromelain may be a useful addition to other therapies used for sinusitis (such as antibiotics) due to its ability to reduce inflammation/swelling.
		Bromelain should be used with caution in people with stomach ulcers, active bleeding, a history of bleeding, taking medications that thin the blood, or prior to some dental or surgical procedures.
	allnutritionals.com /natural-products/bromelain.shtml (1463 words)

	MedlinePlus Herbs and Supplements: Bromelain
		Classified as an herb, bromelain is a sulfur-containing proteolytic digestive enzyme that is extracted from the stem and the fruit of the pineapple plant (Ananas comosus, family Bromeliaceae).
		Allergic reactions to bromelain may occur in individuals allergic to pineapples or other members of the Bromeliaceae family, and in people who are sensitive/allergic to honeybee venom, latex, birch pollen, carrot, celery, fennel, cypress pollen, grass pollen, papain, rye flour, or wheat flour.
		Bromelain should be used with caution in people with stomach ulcers, active bleeding, a history of bleeding, taking medications that thin the blood, or prior to some dental or surgical procedures.
	www.nlm.nih.gov /medlineplus/druginfo/natural/patient-bromelain.html (1762 words)

	Bromelain - For Digestive, Muscle Soreness, Gout, Arthritis, and Inflammation
		Bromelain is found in both the fruit and stem of the pineapple, but the enzyme in supplements comes from the stem.
		Bromelain inhibits the release of certain inflammation-causing chemicals, It also activates a chemical in the blood and tissues that breaks down fibrin, a protein-sugar complex that is partly responsible for blood clotting.
		Bromelain may also keep platelets from sticking to each other and to blood vessel walls, which is a major factor in atherosclerosis (hardening of the arteries).
	www.bodyandfitness.com /Information/Health/Research/bromelain.htm (877 words)

	Bromelain (Site not responding. Last check: 2007-10-10)
		Bromelain is useful in the treatment of a wide range of conditions, but it is particularly effective in relieving inflammation associated with infection and physical injuries.
		Some studies of animals indicate that bromelain (applied to the surface of the skin) may be useful in removing dead tissue from third-degree burns (particularly burns that go through all layers of the skin).
		Bromelain is approved by the German Commission E for the treatment of sinus and nasal swelling following ear, nose, and throat surgery or trauma.
	www.medformation.com /ac/CAM.nsf/conssupplements/Bromelaincs.html (1321 words)

	Bromelain (Site not responding. Last check: 2007-10-10)
		In an extensive study of the effect of bromelain on the gastric mucosa, it was found that bromelain increased the uptake of radioactive sulfur by 50% and glucosamine by 30 -90%.
		Bromelain has been shown to dissolve arteriosclerotic plaque in rabbit aorta in vivo and in vitro.2 It is likely that bromelain also increases vessel wall permeability to oxygen and nutrients while increasing blood fluidity, both of which aid in these conditions.
		Bromelain and papain, due to their use as a meat tenderizer and to clarify beer, are considered as potential ingestive allergens and may represent an unrecognized cause of an allergic reaction following a meal.
	www.thorne.com /altmedrev/fulltext/bromelain1-4.html (5327 words)

	Greenwood Health Systems ... Bromelain (Site not responding. Last check: 2007-10-10)
		Bromelain, derived from the stem of pineapple, is a digestive enzyme that breaks down protein.
		Bromelain must be obtained from supplements to be nutritionally beneficial for the joints.
		Bromelain's effectiveness is due to its ability to reduce the harmful prostaglandins in the body that cause pain and inflammation and block the absorption of nutrients through the tissues.
	greenwoodhealth.net /np/bromelain.htm (283 words)

	Research on Bromelain
		The proteolytic effect of bromelain increased as the concentration of plasma decreased, with EC50 ranging from >1000 microg/ml for 100% plasma to approximately 1 microg/ml in the absence of plasma, indicating the presence of an inhibitor of bromelain in plasma.
		The thiol protease, bromelain, an extract from pineapple stem, was suggested to have antithrombotic and anticoagulant activities in vivo.
		Lotz-Winter H. Bromelain, a standardized complex of proteases from the pineapple plant, is absorbed unchanged from the intestine of animals at a rate of 40%; in animal experiments it was found to have primarily anti-edema, antiinflammatory, and coagulation-inhibiting effects.
	www.bromelain.net /herbal-remedies/bromelain/research-on-bromelain (7092 words)

	Bromelain supplement enzyme anti-inflammatory swelling
		BROMELAIN is a proteolytic enzyme derived from the pineapple stem.
		Bromelain: Isolated from the pineapple stem, bromelain is a proteolytic enzyme that easily and efficiently hydrolyzes most soluble proteins such as casein, gelatin, soya, fish, and other proteins, resulting in smaller protein peptides and amino acids.
		Bromelain, unlike the other enzymes mentioned thus far, has a very wide effective range of activity in both acidic and alkaline conditions that allows this enzyme to remain active in a variety of biological environments.
	www.nutriteck.com /bromelain.html (853 words)

	bromelain research information
		Bromelain is the name of a group of powerful protein-digesting, or proteolytic, enzymes that are found in the pineapple plant (Ananas comosus).
		Bromelain can also ease the pain of heartburn and lessen the effects of diarrhea when these conditions are caused by a shortage of digestive enzymes.
		Bromelain reduces tissue swelling that causes the finger numbness, shooting pains, and weakness in the hand associated with this repetitive stress injury.
	www.naturalpharmacy.com /learn-more/bromelain (492 words)

	Bromelain
		Bromelain is not actually a single substance, but rather a collection of protein-digesting enzymes (also called proteolytic enzymes) found in pineapple juice and in the stem of pineapple plants.
		Bromelain (often in combination with other proteolytic enzymes) is used in Europe to aid in recovery from surgery and athletic injuries, as well as to treat sinusitis and phlebitis.
		Bromelain proteases reduce human platelet aggregation in vitro, adhesion to bovine endothelial cells and thrombus formation in rat vessels in vivo.
	healthlibrary.epnet.com /GetContent.aspx?token=e0498803-7f62-4563-8d47-5fe33da65dd4&chunkiid=21619 (1685 words)

	Research on Bromelain
		The thiol protease, bromelain, an extract from pineapple stem, was suggested to have antithrombotic and anticoagulant activities in vivo.
		Bromelain was applied for 10 days with a daily dose of 3000 F.I.P. units and the immunocytotoxicity of blood monocytes and lymphocytes against the leukemic K562 and MDA-MB-231 mammary carcinoma target cells was determined in vitro.
		Lotz-Winter H. Bromelain, a standardized complex of proteases from the pineapple plant, is absorbed unchanged from the intestine of animals at a rate of 40%; in animal experiments it was found to have primarily anti-edema, antiinflammatory, and coagulation-inhibiting effects.
	naturalpharmacy.com /herbal-remedies/bromelain/research-on-bromelain (7098 words)

	Bromelain - Bromelain Digestive Enzyme
		Bromelain is the name of a group of powerful protein-digesting, or proteolytic,enzymes that are found in the pineapple plant (Ananas comosus).
		Bromelain, the bioactive ingredient of the pineapple was first isolated in 1891 and was introduced as a therapeutic supplement in 1957.
		Bromelain is also used in fighting urinary tract infections when combined with trypsin, and because of its natural blood thinning action is helpful in preventing excessive blood platelet stickiness indicating it to decrease thrombopheitis and angina.
	www.herbs-wholesale.com /article/bromelain.asp (722 words)

	bromelain anti-inflammatory, reduce inflammation, digestion, natural healing, swelling, stiffness, arthritis, faster ...
		Bromelain is an enzyme capable of enhancing digestion, thus reducing or eliminating nausea, heartburn, gastric reflux, and other symptoms that accompany non-digestion of foods.
		Bromelain is beneficial in reducing the clumping of platelets (small platelike particles in the blood), thus reducing the risk of stroke.
		Bromelain (from pineapples) is an anti-inflammatory used to aid digestion, accelerate healing, prevent stroke, reduce blood pressure, reduce or eliminate pain.
	www.arborcounty.com /bromelain.asp (421 words)

	iHerb: HerbalGram The Journal of the American Botanical Council
		Bromelain is the proteolytic enzyme from juice wastes of pineapple stem and ripe or unripe fruits combined with solvents, such as acetone or methanol, or following filtration (Leung and Foster, 1996; Samuelsson, 1992; Schulz et al., 1998).
		Bromelain is also used to treat traumatic or post-surgical swelling; Commission E approves the use of bromelain to quell surgical swelling, particularly nasal sinus swelling.
		Bromelain (EC 3.4.22.4) is the genuine mixture of bromelin A and B, the proteolytic enzymes of pineapple fruit, Ananas comosus (L.) Merrill [Fam.
	www.herbalgram.org /iherb/expandedcommissione/he009.asp (1256 words)

	ACS :: Bromelain
		Bromelain is a natural enzyme found in the stem and fruit of the pineapple.
		Bromelain may also be a possible replacement for digestive enzymes in some patients who don’t have enough of their own.
		Bromelain proteases reduce human platelet aggregation in vitro, adhesion to bovine endothelial cells and thrombus formation in rat vessels in vivo.
	www.cancer.org /docroot/ETO/content/ETO_5_3X_Bromelain.asp?sitearea=ETO (1324 words)

	Bromelain
		Bromelain is the collective term for enzymes (principally proteolytic enzymes) derived from the ripe and unripe fruit, as well as the stem and leaves, of the pineapple plant, Ananas comosus, a member of the Bromeliaceae family.
		Bromelain is mainly comprised of cysteine proteases, with smaller amounts of acid phosphatase, peroxidase, amylase and cellulase.
		It is speculated that the possible protective effect of bromelain in murine EAE (experimental allergic encephalomyelitis), the animal model of multiple sclerosis, is due to proteolytic cleavage of accessory molecules involved in the interaction of T lymphocytes and antigen presenting cells, thus increasing the activation threshold of the autoreactive T lymphocytes.
	www.pdrhealth.com /drug_info/nmdrugprofiles/nutsupdrugs/bro_0330.shtml (1609 words)

	Bromelain
		Orally administered bromelain was anecdotally reported to induce clinical and endoscopic remission of ulcerative colitis in two patients whose disease was refractory to multi-agent conventional medical therapy.
		Bromelain is an accelerator of phagocytosis, respiratory burst and Killing of Candida albicans by human granulocytes and monocytes.
		Bromelain is an aqueous extract from pineapple stem that contains proteinases and exhibits pleiotropic therapeutic effects, i.e., antiedematous, antiinflammatory, antimetastatic, antithrombotic, and fibrinolytic activities.
	www.thensome.com /bromelain.htm (3690 words)

	Bromelain Encyclopedia of Alternative Medicine - Find Articles
		Bromelain is most notable for its effectiveness in the reduction of inflammation and decreasing swelling, but the scope of its benefits continues to increase.
		Bromelain is helpful to people with colds due to its ability to reduce mucus and keep it moving out of the body.
		Bromelain has shown to be generally safe when taken in moderate doses, although a preliminary report links an increased heart rate with the use of the supplement.
	findarticles.com /p/articles/mi_g2603/is_0002/ai_2603000230 (882 words)

	Bromelain: anti-inflammatory, digestive aid, appetite suppresant, superior activity
		On the molecular scale, the digestive action of Bromelain is amazingly rapid and effective: a single enzyme molecule can split 30,000 chemical bonds per second and release the same number of amino acids from a protein.
		Bromelain is the least allergenic of all available digestive aids.
		Bromelains are recommended in inflammatory conditions and wound care, nasal or sinus pressure.
	www.intensivenutrition.com /Bromelain.htm (352 words)

	Bromelain (Site not responding. Last check: 2007-10-10)
		Bromelain is a mixture of sulfur-containing protein-digesting enzymes (proteases) from the stem of the pineapple plant.
		Bromelain has been shown to be effective in the reduction of inflammation and helpful in the reduction of swelling.
		Bromelain blocks the production of kinins which are produced during inflammation.
	www.solsticepoint.com /bromelan.htm (80 words)

	Information on Bromelain
		Bromelain is a protein-splitting enzyme derived from the stem of the pineapple plant.
		Bromelain is a mixture of protein processing enzymes that aids in digestion while enhancing the absorption of nutrients from food and supplements.
		Bromelain has been reported to exert a wide variety of beneficial effects on sports injuries, including reducing inflammation in cases of injury or trauma and prevention of swelling after trauma.
	www.vitaminsdiary.com /bromelain.htm (303 words)

	Healing and Scars in Cosmetic Plastic Surgery - BeautySurg.com (Site not responding. Last check: 2007-10-10)
		Bromelain is a protein enzyme derived from the stems of the pineapple plant.
		For best results, Bromelain should be taken on an empty stomach at a dose of 500 mdu or gdu (measured as milk-clotting or gelatin-digesting units, not milligrams) 3 times a day for two weeks before surgery, and one week after.To be effective for surgery, supplementation must begin at least 72 hours before the operation.
		Bromelain has been known to increase blood levels of antibiotics, and should not be taken by anyone allergic to pineapple, bee stings, or olive tree pollen.
	www.beautysurg.com /learn/general_healing6.html (483 words)

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