Where results make sense

About us   |   Why use us?   |   Reviews   |   PR   |   Contact us

Mast-cell stabilising agents to prevent exercise-induced bronchoconstriction Exercise-induced bronchoconstriction, also commonly called exercise-induced asthma, is associated with symptoms such as cough (locker room cough), wheezing, shortness of breath, and chest tightness following exercise. Mast cell stabilizing agents are effective in attenuating exercise-induced bronchoconstriction but their effectiveness compared to bronchodilator agents is unclear. All drugs were effective at attenuating the exercise-induced bronchoconstriction response but to varying degrees even within the same individual. www.cochrane.org /reviews/en/ab002307.html   (906 words)

Bronchoconstriction - Wikipedia, the free encyclopedia Bronchoconstriction is the constriction of the airways in the lungs due to the tighting of surrounding smooth muscle, with consequent coughing, wheezing, and shortness of breath. The underlying cause of this type of bronchoconstriction appear to be the large volume of cool, dry air inhaled during strenuous exercise. EIB "The underlying cause of this type of bronchoconstriction appear to be the large volume of cool, dry air inhaled during strenuous exercise. en.wikipedia.org /wiki/Bronchoconstriction   (550 words)

EVOLUTION IN ASTHMA — EVOLUTION OF BRONCHIAL RESPONSE TO EPINEPHRINE The severity of alpha-induced bronchoconstriction depends on the evolution in asthma and it seems to be one of the causes of asthmatics sudden death. As it is known, the main pathogenetic syndrome determining all the clinical symptoms of bronchial asthma (cough, dyspnea, wheezing and breathlessness) is the airflow obstruction. At this stage the ratio between the bronchodilation and bronchoconstriction to epinephrine is probably 1:1 that is deduced from the lack of proven response to this agent. www.angelfire.com /cantina/astma   (3757 words)

UpToDate Exercise-induced bronchoconstriction Levels of bronchoconstrictive and inflammatory mediators are increased, particularly leukotrienes LTC4 and LTD4 [13], histamine [14], and interleukin (IL)-8 [15]. In patients with EIB, the initial bronchodilation is followed by bronchoconstriction, which begins by three minutes, generally peaks within 10 to 15 minutes, and resolves by 60 minutes (show figure 1). In most patients with EIB, bronchoconstriction is followed by a refractory period, during which repeated exertion causes less bronchoconstriction [23]. patients.uptodate.com /print.asp?print=true&file=asthma/13974   (561 words)

Bronchodilator - Wikipedia, the free encyclopedia Short-acting medications provide quick or "rescue" relief from acute bronchoconstriction. Patients who regularly or frequently need to take short-acting beta2-agonists should consult their doctor, as such usage indicates uncontrolled asthma, and their routine medications may need adjustment. Long-acting beta2-agonists These are long-term medications taken routinely in order to control and prevent bronchoconstriction. en.wikipedia.org /wiki/Bronchodilator   (623 words)

Definition: Bronchoconstriction The airways (the tubes that carry air into and out of the lungs) are surrounded by a type of muscle called smooth muscle. This narrowing of the airways is known as bronchoconstriction. Along with inflammation of the airways, it leads to symptoms such as coughing, wheezing, and shortness of breath. kidshealth.org /parent/asthma_basics/dictionary/bronchoconstriction.html   (130 words)

Word! Bronchoconstriction Actually, bronchoconstriction affects the airways in a person's lungs. When bronchoconstriction occurs, the muscles surrounding the airways contract, or tighten. Bronchoconstriction happens to people who have asthma, but asthma medicines can help relax the muscles in the airways and make breathing easier. kidshealth.org /kid/word/b/word_bronchoconstriction.html   (127 words)

Leukotriene Bronchoconstriction Induced by Allergen and Exercise -- O'BYRNE 161 (2): 68 -- American Journal of ... The bronchoconstriction that occurs during the early and late responses is in large part caused by allergen-induced release Inhibition of exercise-induced bronchoconstriction by MK-571, a potent leukotriene D4-receptor antagonist. Effect of a cysteinylleukotriene receptor antagonist, ICI 204-219, on allergen-induced bronchoconstriction and airway hyperactivity in atopic subjects. ajrccm.atsjournals.org /cgi/content/full/161/2/S1/S68   (2618 words)

Respiratory Research | Full text | Role of acetylcholine and polyspecific cation transporters in serotonin-induced ... In order to test this hypothesis, 5-HT-induced bronchoconstriction of small intrapulmonary airways and the sensitivity of this response to corticosterone were studied videomorphometrically in precision-cut lung slices (PCLS) [10-12] taken from OCT1-3-deficient mice [13,14]. The present data clearly demonstrate an epithelium-dependent component of 5-HT-induced bronchoconstriction in the mouse, consistent with the results of a previous study on the mouse trachea [3]. In view of the electrogenic properties of OCTs [20], the acute inhibitory effect of corticosterone on 5-HT-induced bronchoconstriction might be caused by modulation of membrane potential, but the underlying signal transduction cascade still awaits to be clarified. respiratory-research.com /content/7/1/65   (4218 words)

RedOrbit - Health - Airway Responses to Aerosolized Brevetoxins in an Animal Model of Asthma Unexpectedly however, significant inhibition of the crude PbTx-induced bronchoconstriction was seen with the antiallergic agent cromolyn sodium and the histamine H^sub 1^ antagonist diphenhydramine, suggesting that histamine also contributes to the response. Atropine blockade of the PbTx-induced bronchoconstriction is consistent with previous in vitro studies using dog trachealis muscle (12) and in vivo studies in guinea pigs where PbTx was given parenterally (41). Thus, unlike the constrictor responses that appear to be dependent on the presence of a functional group, the different TMV responses may be linked to both the presence and the chemical structure of the side chain. www.redorbit.com /news/display?id=117327   (6349 words)

Mayo Clinic Proceedings Bronchoconstriction observed after edetate disodium inhalations has been shown to be due to chelation of calcium. We believe that the laryngospasm and worsening bronchoconstriction in our patient were caused by an adverse effect of edetate disodium. Finally, normal findings on direct laryngoscopy while she was experiencing residual symptoms and the presence of severe hypoxemia with an increased alveolar-arterial oxygen gradient exclude vocal cord dysfunction. www.mayoclinicproceedings.com /inside.asp?AID=1388&UID=   (1783 words)

Anticholinergic (Parasympatholytic) When activated – c-fibers produce an afferent nerve impulse to CNS that results in a reflex cholinergic efferent impulse to cause constriction of ASM and release of secretions from mucous glands as well as cough. Since atropine and its derivatives are competitive inhibitors of Ach at the neuroeffector junction, such antagonists should block parasympathetic reflex bronchoconstriction. receptors by a drug prevents stimulation of the receptor by Ach and thereby preventing stimulation induced bronchoconstriction and mucous release. www.salisbury.edu /healthsci/RESP/Classes/RLJoyner/Fall/AHPH544/4parasym.htm   (424 words)

Viral Infection Induces Dependence of Neuronal M2 Muscarinic Receptors on Cyclooxygenase in Guinea Pig Lung -- Kahn et ... the efferent limb of the reflex arc is abnormal, as the bronchoconstriction bronchoconstriction is not altered by 1 mg/kg indomethacin (b). The effect of indomethacin on potentiation of vagally induced bronchoconstriction by gallamine is altered after virus infection. www.jci.org /cgi/content/full/98/2/299   (5502 words)

Larynx vs. esophagus as reflexogenic sites for acid-induced bronchoconstriction in dogs -- Ishikawa et al. 86 (4): 1226 ... Bronchoconstriction in asthmatic patients is frequently associated with gastroesophageal reflux. Cigarette smoke-induced bronchoconstriction: causative agents and role of thromboxane receptors. The significance of the reflex bronchoconstriction provoked by gastroesophageal reflux in bronchial asthma. jap.physiology.org /cgi/content/full/86/4/1226   (2583 words)

ACOFP - Member Publications   (Site not responding. Last check: 2007-11-01) A review of the literature indicates the gases and aerosols used in the deployment of an airbag may produce bronchoconstriction in persons with a history of asthma. They did conclude that acid aerosols can cause bronchoconstriction in subjects with mild asthma, but the magnitude of the lung response depends upon the concentration and the particle size distribution of the aerosol and that the lower the pH of the acid aerosol, the more the stimulus exists for lung function changes. Subjects in accidents where airbags deploy may not be able to use Beta-agonist therapy as rapidly as those in the studies, resulting in worsening of their asthmatic symptoms beyond what was seen in controlled studies. www.acofp.org /member_publications/camay_02.htm   (1288 words)

Ovalbumin Sensitization Changes the Inflammatory Response to Subsequent Parainfluenza Infection: Eosinophils Mediate ... to the bronchoconstriction in the absence of pilocarpine. Results are expressed as the ratio of vagally induced bronchoconstriction in the presence of pilocarpine to the response of vagal stimulation in the absence of pilocarpine. Vagally induced bronchoconstriction in sensitized virus-infected animals given heparin (filled diamonds, n = 5) was significantly decreased (P = 0.0004) to become similar to sensitized control animals. www.jem.org /cgi/content/full/190/10/1465   (6375 words)

Management of exercise-induced bronchoconstriction Exercise-induced bronchoconstriction (EIB) is a common clinical manifestation of asthma, occurring in 70% to 80% of asthmatics. Evidence suggests that exercise and the ensuing bronchoconstriction do not contribute to a worsening of asthmatic inflammation. Asthmatics should not be discouraged from exercising, and, with adequate management, most patients should be able to exercise regularly with only minor symptoms. www.pulsus.com /Respir/06_04/inma_ed.htm   (611 words)

Characterization of adenosine receptor(s) involved in adenosine-induced bronchoconstriction in an allergic mouse model ... Characterization of adenosine receptor(s) involved in adenosine-induced bronchoconstriction in an allergic mouse model -- Fan et al. We recently reported that adenosine caused bronchoconstriction and enhanced airway inflammation in an allergic mouse model. Adenosine-mediated bronchoconstriction and lung inflammation in an allergic mouse model. ajplung.physiology.org /cgi/content/full/284/6/L1012   (3530 words)

Inflazyme Announces Positive Preclinical Results For Apanol(TM) Analysis of the data shows that acute dosing of Apanol(TM) protected against 90% of the bronchoconstriction associated with the late phase of an asthma attack. The study, conducted at Mount Sinai Hospital in Miami Beach, Florida, measured bronchoconstriction and hyper-responsiveness in two groups of sheep. In each group, researchers measured bronchoconstriction and responsiveness to external stimuli against historical responses recorded several weeks prior to the test. www.prnewswire.com /cgi-bin/stories.pl?ACCT=105&STORY=/www/story/127976   (670 words)

Role of cysteinyl leukotrienes in adenosine 5`-monophosphate induced bronchoconstriction in asthma -- Rorke et al. 57 ... Role of cysteinyl leukotrienes in adenosine 5`-monophosphate induced bronchoconstriction in asthma -- Rorke et al. Role of cysteinyl leukotrienes in adenosine 5`-monophosphate induced bronchoconstriction in asthma The leukotriene receptor antagonist zafirlukast inhibits sulfur dioxide-induced bronchoconstriction in patients with asthma. thorax.bmjjournals.com /cgi/content/full/57/4/323   (2552 words)

Combined Lidocaine and Salbutamol Inhalation for Airway Anesthesia Markedly Protects Against Reflex Bronchoconstriction ... Makker, HK, Holgate, ST (1993) The contribution of neurogenic reflexes to hypertonic saline-induced bronchoconstriction in asthma. Enright, PL, McNally, JF, Souhrada, JF (1980) Effect of lidocaine on the ventilatory and airway responses to exercise in asthmatics. Laube, BL, Norman, PS, Adams, GK (1992) The effect of aerosol distribution on airway responsiveness to inhaled methacholine in patients with asthma. www.chestjournal.org /cgi/content/full/118/2/509   (3104 words)

Identification of A3 Receptor- and Mast Cell-Dependent and -Independent Components of Adenosine-Mediated Airway ... Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction. Characterization of adenosine receptors involved in adenosine-induced bronchoconstriction in allergic rabbits. The effect of inhaled ipratropium bromide alone and in combination with oral terfenadine on bronchoconstriction provoked by adenosine 5'-monophosphate and histamine in asthma. www.jimmunol.org /cgi/content/full/171/1/331   (4638 words)

Research Abstract: 1986- 07-01 The Roles of pH, Titratable Acid and Specific Chemical Composition in Mediating Effects ... Aerosols of unbuffered acids caused little bronchoconstriction down to pH 2, whereas aerosols of buffered HCL and H2SO4 (buffered with glycine) caused titratable acidity-dependent bronchoconstriction in 7 of 8 subjects, suggesting that titratable acidity might be a more important determinant of bronchoconstrictor potency than is pH. Finally, to determine if assessment of airway vascular permeability or morphologic evidence of airway injury would be more sensitive indicators of the effects of acid aerosols than is bronchoconstriction, we examined the effects of exposure to a range of atmospheres containing aerosols of HSO3- and of HCL on these parameters in male Hartley guinea pigs. Although we were able to cause bronchoconstriction during exposure to acid aerosols at pH 1, no exposure condition caused increased tracheal vascular permeability or produced morphologic evidence of airway injury on light microscopy of Giemsa stained sections. www.arb.ca.gov /research/abstracts/a4-113-32.htm   (300 words)

PCCU Volume 19, Lesson 24 Bronchodilators play a central role in symptomatic relief of acute bronchoconstriction in both conditions and are the primary maintenance therapy for COPD patients. Asthmatics with any stage of persistent disease should be treated with inhaled glucocorticosteroids as their first line of control and maintenance, but the majority also benefit from use of a long-acting inhaled bronchodilator as part of their maintenance regimen. Because cholinergic stimulation is only one of many contributing factors leading to bronchoconstriction, anticholinergics can only partially reverse the airflow obstruction of COPD and asthma. www.chestnet.org /education/online/pccu/vol19/lessons23_24/print24.php   (3531 words)

Pretreatment with Antibody to Eosinophil Major Basic Protein Prevents Hyperresponsiveness by Protecting Neuronal M2 ... in the presence of pilocarpine to the bronchoconstriction in the , inhibited vagally-induced bronchoconstriction by 67% (B2/B1 was 0.33±0.08). bronchoconstriction in a dose-related manner (data not shown). www.jci.org /cgi/content/full/100/9/2254   (5565 words)

Exercise-Induced_Asthma Asthma - a chronic usually reversible illness marked by episodes of bronchoconstriction and airway inflammation. Inflammatory response changes permeablility of cells to water causing the loosening of tight junctions of the epithelial cells whcih then allows for easier access of substances to bronchial or vascular smooth muscle to cause bronchoconstriction. LTRAs inhibit bronchoconstriction caused by several kinds of inhalational challenges including cold air. w3.ouhsc.edu /phar5442/Lectures/Exerciseasthma.html   (552 words)

Frequent Colds This narrowing or bronchoconstriction is the primary cause for the shortness of breath and wheezing seen with asthma sufferers. The entire goal of treatment and prevention of asthma is through the avoidance or treatment of this bronchoconstriction. These are oral medications (pills) taken once or twice a day which function to reduce the migration of inflammatory cells to the lungs. www.medhelp.org /forums/FamilyPractice/messages/105.html   (843 words)

Expert   (Site not responding. Last check: 2007-11-01) Bronchoconstriction (meaning that the muscles that encircle the airways tighten or go into spasm) Triggers irritate the airways and result in bronchoconstriction. Symptoms and bronchoconstriction caused by triggers tend to be immediate, short-lived, and rapidly reversible. users.rowan.edu /~jackso00/Expert.html   (948 words)

Changes in FVC During Methacholine-Induced Bronchoconstriction in Elderly Patients With Asthma : Bronchial ... Changes in FVC During Methacholine-Induced Bronchoconstriction in Elderly Patients With Asthma : Bronchial Hyperresponsiveness and Aging -- Cuttitta et al. This risk is aggravated by a reduced perception of bronchoconstriction. Connolly, MJ, Crowley, JJ, Charan, NB, et al (1992) Reduced subjective awareness of bronchoconstriction provoked by methacholine in elderly asthmatic and normal subjects as measured on a simple awareness scale. www.chestjournal.org /cgi/content/full/119/6/1685   (2656 words)

Try your search on: Qwika (all wikis)

About us   |   Why use us?   |   Reviews   |   Press   |   Contact us   Copyright © 2005-2007 www.factbites.com Usage implies agreement with terms.