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Topic: Bruce Merrifield


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In the News (Tue 17 Nov 09)

  
  The Scientist : Bruce Merrifield dies
Bruce Merrifield, one of the fathers of modern peptide synthesis and recipient of the 1984 Nobel Prize in Chemistry, died of a long illness last week (May 14) at his home in Cresskill, N.J., according to Rockefeller University.
Merrifield was best known as the creator of solid phase peptide synthesis, a process that enabled the systematic study of the structure of proteins.
Bruce Merrifield's scientific legacy is unquestioned; his work is the foundation on which all advances in the study of biologically active peptides have been made and his Nobel Prize was simple recognition of this fact.
www.the-scientist.com /news/display/23479   (831 words)

  
 Bruce Merrifield, Nobel Prize winner, dies - Boston.com
Bruce Merrifield, whose greatly accelerated process for making proteins helped develop an array of medications and earned him the 1984 Nobel Prize in chemistry, has died.
Proteins are key components of all living organisms, and Merrifield's innovation allowed researchers to make peptides and proteins in a matter of days, rather than years, according to The Rockefeller University in Manhattan, where he worked.
Merrifield is survived by his wife, five daughters, one son and 16 grandchildren.
www.boston.com /news/nation/articles/2006/05/19/bruce_merrifield_nobel_prize_winner_dies   (317 words)

  
 Bruce Merrifield, 84; won Nobel for work in proteins - The Boston Globe
LOS ANGELES -- Bruce Merrifield, the Henry Ford of the biological world who received the 1984 Nobel Prize in chemistry for automating the previously daunting process of synthesizing complex proteins, died May 14 at his home in Creskill, N.J., after a long illness.
Merrifield's inspiration was to take the first amino acid in the chain and attach it to a bead of insoluble plastic.
Merrifield quickly realized that the highly repetitive process could be automated, though few experts agreed with him.
www.boston.com /news/globe/obituaries/articles/2006/05/22/bruce_merrifield_84_won_nobel_for_work_in_proteins/?page=1   (960 words)

  
 Robert Bruce Merrifield
Robert Bruce Merrifield (July 15, 1921 – May 14, 2006) was an American biochemist who won the Nobel Prize in Chemistry in 1984.
Merrifield's method greatly stimulated progress in biochemistry, pharmacology and medicine, making possible the systematic exploration of the structural bases of the activities of enzymes, hormones and antibodies.
After a long illness R. Bruce Merrifield passed away on Sunday, May 14, 2006 at the age of 84.
www.ekenjy.co.za /wiki/Robert_Bruce_Merrifield   (543 words)

  
 1998 ABRF Award to Dr. Bruce Merrifield
On May 26, 1959, Dr. Merrifield began a new page in his laboratory notebook entitled, "A New Approach to the Continuous, Stepwise Synthesis of Peptides." He began, "There is a need for a rapid, quantitative method for synthesis of long chain peptides", and he then laid out his strategy for devising such a method.
Merrifield technologies are the cornerstone of many ABRF resource and research laboratories, and have formed the foundation for hundreds of successful businesses, both large and small.
Merrifield has also made important contributions to the nurturing and education of several generations of chemists, who continue to push the frontiers of the chemistry of peptides and other compounds.
www.abrf.org /ABRFNews/1998/June98/jun98Merrifield.html   (419 words)

  
  Robert Bruce Merrifield -- Facts, Info, and Encyclopedia article   (Site not responding. Last check: 2007-09-29)
Robert Bruce Merrifield is an (A native or inhabitant of the United States) American (Someone with special training in biochemistry) biochemist.
He was born in (A city in northeastern Texas (just west of Dallas); a major industrial center) Fort Worth, (The second largest state; located in southwestern United States on the Gulf of Mexico) Texas, 15 July, 1921, the only son of George E. Merrifield and Lorene née Lucas.
In 1923 the family moved to (A state in the western United States on the Pacific; the 3rd largest state; known for earthquakes) California where he attended nine grade schools and two high schools before graduating from Montebello High School in 1939.
www.absoluteastronomy.com /encyclopedia/r/ro/robert_bruce_merrifield.htm   (429 words)

  
 Bruce Merrifield, Nobel Laureate, UCLA Alumnus (UCLA Gateway)
Robert Bruce Merrifield came to UCLA as a transfer student from Pasadena City College.
Knobler wrote, "Merrifield was awarded the Nobel Prize in Chemistry for the development of a method for the synthesis of polypeptides.
Robert Bruce Merrifield was born July 21, 1921.
www.ucla.edu /about/nobelwinners/merrifield.html   (183 words)

  
 Robert Bruce Merrifield Summary
Bruce Merrifield was born July 15, 1921, in Fort Worth, Texas, the only son of George E. and Lorene Lucas Merrifield.
Merrifield has received many academic and professional awards, including the Ralph F. Hirschmann Award in Peptide Chemistry from the American Chemical Society (1990); the Josef Rudinger Award (1990), and the Seaborg Medal (1993).
Robert Bruce Merrifield (July 15 1921 – May 14 2006) was an American biochemist who won the Nobel Prize in Chemistry in 1984.
www.bookrags.com /Robert_Bruce_Merrifield   (2634 words)

  
 Chemical & Engineering News: Latest News - Nobel Laureate R. Bruce Merrifield Dies At 84
Robert Bruce Merrifield, a biochemist who won the 1984 Nobel Prize in Chemistry for a method he named solid-phase peptide synthesis, died on May 14 at his home in Cresskill, N.J., after a long illness.
Merrifield cut synthesis time from years to days by anchoring the first building block of the protein to a polymer.
Equally devoted to science and to his large family, Merrifield is survived by his wife, Elizabeth, a biologist who worked in his lab; one son and five daughters; and 16 grandchildren.
pubs.acs.org /cen/news/84/i22/8422merrifield.html   (454 words)

  
 Professor Bruce Merrifield - Independent Online Edition > Obituaries
The biochemist and organic chemist Bruce Merrifield won the 1984 Nobel Prize in Chemistry in recognition of his outstanding achievement in the methodology of the chemical synthesis of proteins.
Robert Bruce Merrifield was born in Texas in 1921 and, his parents having moved to California in 1923, took a BA in chemistry and then a PhD in biochemistry at the University of California, Los Angeles in 1949.
All who met Bruce Merrifield found him a courteous, methodical and unassuming man. He married his wife Elizabeth (Libby) in 1949, the day before they left Los Angeles for New York; they had a son and five daughters, and 16 grandchildren, to all of whom he was devoted.
news.independent.co.uk /people/obituaries/article1205992.ece   (1299 words)

  
 The Rockefeller University - Obituary: Robert Bruce Merrifield dies at 84
In October 1984, Robert Bruce Merrifield was interviewed by the Star-Ledger of New Jersey after he won the Nobel Prize in Chemistry.
Merrifield’s careful, methodical and optimistic approach to research was well known to everyone around him, and when his groundbreaking discovery of the technique known as solid phase peptide synthesis resulted in the Nobel Prize, the only person surprised by the news was the man himself.
Merrifield is survived by his wife Elizabeth, one son, five daughters, and 16 grandchildren.
www.rockefeller.edu /benchmarks/benchmarks_060906_f.php   (387 words)

  
 Chemical & Engineering News: ACS News - Paying Tribute To Bruce Merrifield
Merrifield is best known for the invention and development of solid-phase peptide synthesis, which revolutionized synthetic organic chemistry.
Merrifield spent virtually his entire career, which spanned six decades, at Rockefeller University, and the plaque will be hung near his laboratory on the fourth floor of Flexner Hall.
John M. Stewart, who worked with Merrifield from 1952 to 1968 and is now a professor of biochemistry at the University of Colorado Health Sciences Center, recalled their work on the design of the first automated solid-phase peptide synthesizer, which now belongs to the Smithsonian Institution.
pubs.acs.org /cen/acsnews/84/8451acsnews.html   (1274 words)

  
 MSU Chemistry - Gallery of Chemists' Photo-Portraits and Mini-Biographies - Individual
Using this technique Merrifield synthesized the nonapeptide bradykinin in just 27 hours, and in 1969 he synthesized ribonuclease, the first enzyme to be prepared synthetically from its amino acid components (124 amino acid residues).
Prior to Merrifield's time, using conventional reactions in solution, peptide synthesis was exceedingly tedious and, for very large peptides, virtually impossible.
Merrifield was born in Texas but grew up in California.
www.chemistry.msu.edu /Portraits/PortraitsHH_Detail.asp?HH_LName=Merrifield   (254 words)

  
 NFDA Calendar - Fall City Meetings   (Site not responding. Last check: 2007-09-29)
Merrifield will explain how both individuals and organizations operate in dynamic equilibriums in which forces for change are neutralized by forces against change.
Merrifield has focused on maximizing the effectiveness of independent distribution channels, high performance service management and the effects of electronic commerce on distribution channels.
Merrifield is the honorary Chairman of a national distributor of security hardware.
www.nfda-fastener.org /ducalendar/spring2007/education.cfm   (1098 words)

  
 AACC | R. Bruce Merrifield
Pasadena City College, CA During nearly 60 years as a research chemist, Dr. Bruce Merrifield has helped unlock the mysteries of biological life with his scientific investigations of protein and peptide synthesis.
Merrifield is best known for his solid phase peptide synthesis, for which he was awarded the Nobel Prize in 1984.
Merrifield finished high school in Pasadena in 1939 and enrolled at Pasadena Junior College, now known as Pasadena City College.
www.aacc.nche.edu /Content/NavigationMenu/AboutAACC/Awards/AlumniAward/2001Winners/R__Bruce_Merrifield.htm   (193 words)

  
 Record Article   (Site not responding. Last check: 2007-09-29)
Sponsored by the American Peptide Society, the award is named in honor of R. Bruce Merrifield, Ph.D., a recipient of the 1984 Nobel Prize in chemistry and a professor at Rockefeller University.
The Merrifield award is given for outstanding career achievement in peptide research.
The Merrifield award was presented in June at the combined Second International Peptide Symposium and 17th American Peptide Symposium in San Diego.
record.wustl.edu /archive/2001/09-21-01/articles/marshall.html   (448 words)

  
 Bruce Merrifield; Nobel Prize-winning biochemist; 84 | The San Diego Union-Tribune
Merrifield died at his Bergen County, N.J., home May 14 after a long illness, family members said Friday.
Proteins are key components of all living organisms, and Dr. Merrifield's innovation allowed researchers to make peptides and proteins in a matter of days, rather than years, according to The Rockefeller University in Manhattan, where he worked.
Merrifield was born in Fort Worth, Texas, in 1921.
www.signonsandiego.com /uniontrib/20060524/news_1m24merrif.html   (252 words)

  
 R. Bruce Merrifield, Who Won Nobel Prize in Chemistry, Dies at 84 - New York Times
Bruce Merrifield, who won a Nobel Prize in Chemistry for developing a much quicker way to synthesize proteins, streamlining many medical and scientific experiments, died Sunday at his home in Cresskill, N.J. He was 84.
Born in Fort Worth, Robert Bruce Merrifield received a bachelor's degree in chemistry from the University of California at Los Angeles, in 1943.
Merrifield first reported his protein-making technique in 1962 and later built a machine to churn out proteins automatically.
www.nytimes.com /2006/05/20/nyregion/20merrifield.html?ex=1305777600&en=746d4d22e9194d4b&ei=5088&partner=rssnyt&emc=rss   (706 words)

  
 Bruce Merrifield, Nobel Prize-winning biochemist, dies at 84 (phillyBurbs.com) | New Jersey News
Bruce Merrifield, Nobel Prize-winning biochemist, dies at 84 (phillyBurbs.com)
Bruce Merrifield, Nobel Prize-winning biochemist, dies at 84
"Merrifield's methodology has brought about a revolution in peptide and protein chemistry," the Royal Swedish Academy of Sciences said in recognizing his work with its Nobel Prize in 1984.
www.phillyburbs.com /pb-dyn/news/104-05192006-658890.html   (486 words)

  
 R. Bruce Merrifield Biography | World of Chemistry
Woolley had discovered and on the dinucleotide growth factors Merrifield had discovered during his graduate study.
Merrifield's research required him to isolate biologically active peptides.
Merrifield and his wife, Elizabeth, live in Cresskill, New Jersey.
www.bookrags.com /biography/r-bruce-merrifield-woc   (1169 words)

  
 Nobel Winner Bruce Merrifield - washingtonpost.com
Robert Bruce Merrifield, 84, the Henry Ford of the biological world who received the 1984 Nobel Prize in chemistry for automating the previously daunting process of synthesizing complex proteins, died May 14 at his home in Creskill, N.J., after a long illness.
Proteins are key components of all living organisms, and Merrifield's innovation allowed peptides and proteins to be made in days rather than years, according to Rockefeller University in New York, where he worked.
By his own count, Dr. Merrifield attended 40 schools as his father moved from job to job along the California coast.
www.washingtonpost.com /wp-dyn/content/article/2006/05/21/AR2006052101243_pf.html   (320 words)

  
 Bruce Merrifield - Book Keynote Speaker Bruce Merrifield from Speak Inc for your next event!
Since early '94, Bruce has focused full-time on how electronic commerce is and will continue to change traditional distribution channels.
On the side, Bruce is an honorary Chairman and a significant shareholder of a West Coast distribution firm, which has: 350 employees, 13 locations, and current sales over $120 million.
Bruce is a graduate of Princeton University (BA - 1972) and Harvard University Graduate School of business (MBA - 1974).
www.speakinc.com /keynote-speakers/bruce-merrifield   (246 words)

  
 Oxford University Press: Bruce Merrifield: Bruce Merrifield
Bruce Merrifield, eminent American scientist, 1984 Nobel Prize winner and professor at The Rockefeller University, is noted for his single-handed development of solid phase peptide synthesis.
The progress of biochemistry and related fields is closely correlated with the availability of pure peptides, and in this volume, Merrifield describes nearly 40 years of progress.
Merrifield's Nobel Prize is probably unique in modern science, in that it was awarded for work conceived in his own mind and achieved by his own hand.
www.oup.com /us/catalog/25534/subject/OrganicInorganicOrganometallicCh/~~/dmlldz11c2EmY2k9OTc4MDg0MTIxODQyMA==   (246 words)

  
 R. Bruce Merrifield - Oregon Institute of Science and Medicine
Dr. Merrifield is the originator of solid-phase peptide synthesis, with which he carried out the first laboratory synthesis of an enzyme.
In recognition of these accomplishments, he was awarded the Nobel Prize in Chemistry in 1984.
Merrifield is Emeritus Professor at Rockefeller University where he directs a group of scientists working on various aspects of the development and application of solid phase synthesis in protein chemistry.
www.oism.org /oism/s32p19.htm   (76 words)

  
 KLTV 7 Tyler-Longview-Jacksonville, TX: Bruce Merrifield, Nobel Prize-winning biochemist, dies at 84
KLTV 7 Tyler-Longview-Jacksonville, TX: Bruce Merrifield, Nobel Prize-winning biochemist, dies at 84
CRESSKILL, N.J. Bruce Merrifield, who won the 1984 Nobel Prize for Chemistry for work that helped simplify research and assisted in the development of various medications, has died.
A private service was scheduled for tomorrow, with burial to follow at Brookside Cemetery in Englewood.
www.kltv.com /global/story.asp?s=4926836   (220 words)

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