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Topic: Bufotoxin

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In the News (Tue 23 Apr 19)

  It:Bufotoxin - ChemWiki
The occurrence of a new type of bufotoxin, in which L-glutamine replaces the arginine residue of hitherto known bufotoxin, in the skin of the North American toad, B. americanus, is reported.
Bufotoxins are a group of toxic substances that are found in many toads that belong to the Bufo genus.
In this remarkable study the average yield of crude bufotoxin from Bufo vulgaris (800 males and 400 females) was found to be 1.34 mg/toad, while the female was found to yield 1.23 mg on the average of bufotalin.
www.ch.ic.ac.uk /wiki/index.php?title=It:Bufotoxin&redirect=no   (1192 words)

 Erowid Psychoactive Toads Vault : Health #1
Bufotoxins were originally isolated from the parotoid glands of toads, but have since been seen in various plants and mushrooms (Siperstein et al, 1957; Lincoff & Mitchel, 1977; Kibmer & Wichtl, 1986).
BUFOTOXINS: Is the name of a collection of compounds found in the toad venom which may be secreted into toad skin or found in 2 glands behind the eyes, called parotid glands (Tyler, 1976).
Bufotoxins may also be specificially applied to the conjugates of a bufagin with suberylargine.
www.erowid.org /animals/toads/toads_health1.shtml   (3235 words)

 10.01.2002 - New UC Berkeley study suggests promise of Chinese herbal medicine as treatment for chronic hepatitis B
Two of the 27 studies specifically looked at bufotoxin, an extract from the skin of the toad Bufo gargarizans.
In particular, bufotoxin combined with interferon alfa was significantly more effective than interferon alfa alone in measures of HBeAg and HBV DNA, but not for measures of the surface antigen.
"Bufotoxin and kurorinone have been singled out as having the best potential for being investigated for drugs," said McCulloch, a licensed acupuncturist for 16 years.
www.berkeley.edu /news/media/releases/2002/10/01_hbmed.html   (746 words)

 Ocean Learning Center   (Site not responding. Last check: 2007-10-20)
The toxin, bufotoxin, usually oozes out of the glands, but it can be squirted in a spray for a short distance.
The toxin also is released when pressure is applied to the glands such as results from handling a toad or an animal such as a dog or cat taking it in its mouth.
A substance modified from bufotoxin is used in Japan as a hair-restorer.
www.aquariumofpacific.org /OLC/detail.asp?browseBy=topic&x=&y=184   (1033 words)

 Chinese Herbal Cure for Hepatitis-B
It was seen that combination of Chinese herbal treatments with interferon alfa were 1.5 to 2 times more effective as interferon alfa in reducing the hepatitis B viral load to undetectable level for all three measure of infection.
In particular bufotoxin combined with interferon alfa was significantly more effective than interferon alfa alone in measures of HbeAg and HBV DNA, but not form the measures of the surface antigen.
"Bufotoxin and Kurorinone have been signaled out as having the best potential for being investigated for drugs" a licensed acupuncturist for 16 years.
www.heart-intl.net /HEART/010105/ChineseHerbalCure.htm   (1632 words)

 Halfbakery: Improve Cane Toad Predators
Like them, their progeny will have acquired bufotoxin resistance by the time they are ready to go it alone.
Maybe there is a baking doctor or pharmacist who knows this answer off the top of his or her head, or where to find it.
Bufotoxin is actually a collection of compounds (including the one you refer to).
www.halfbakery.com /lr/idea/Improve_20Cane_20Toad_20Predators   (1059 words)

 bufotoxin page - bufotoxin chemical formula
Bufotoxins are a family of toxic substances found in the parotoid glands, skin and venom of many toads (genus Bufo); other amphibians; and other plants and mushrooms (Siperstein et al, 1957; Lincoff and Mitchel, 1977; Kibmer and Wichtl, 1986).
The term bufotoxin can also be used specifically to describe the conjugate of a bufagin with suberylargine (Chen and Kovarikova, 1967).
Extract from the skin of certain Asian toads, such as Bufo gargarizans, is often found in certain Chinese folk remedies.
www.theramonitor.com /bufotoxin.html   (125 words)

 Pine Street Foundation | HIFU
Chinese herbal medicine significantly increased seroreversion of HBsAg and was equivalent to interferon alfa in seroreversion of HBeAg and hepatitis B virus (HBV) DNA; Chinese herbal medicine combined with interferon alfa significantly increased seroreversion of HBsAg, HBeAg, and HBV DNA.
Bufotoxin in combination with interferon in the treatment of chronic hepatitis B: 43 cases [in Chinese].
Zhang YL, Liu H. Bufotoxin and interferon in the treatment of chronic hepatitis B: 30 cases [in Chinese].
www.psmerg.org /articles/ajph.html   (4282 words)

 [No title]
The bufogenins and bufotoxins together are known as bufodienolides.
It was found that the bufodienolides present in toad venom from Bufo marinus are both similar in their chemical structures as well as their pharmacological properties to digitalis (Chi et al, 1998; Lim et al, 1997).
According to Lim et al (1997), the exact mechanism of the bufotoxins are still being debated, but in general there is agreement among the scientific community that they inhibit the Na+/K+ ATPase found on cellular membranes.
sulcus.berkeley.edu /mcb/165_001/papers/manuscripts/_515.html   (3258 words)

 Cane Toad Encyclopedia Article @ Invaded.org   (Site not responding. Last check: 2007-10-20)
Adult Cane Toads possess enlarged parotoid glands behind the eyes, and other glands across the back.
When threatened, the Cane Toad secretes a milky-white fluid known as bufotoxin from these glands.
Bufotoxin contains components that are toxic to many animals.
www.invaded.org /encyclopedia/Cane_Toad   (3384 words)

 Bufo Toads - PetsMeds and PetsSmart Products   (Site not responding. Last check: 2007-10-20)
The marine toad is a brown to grayish-brown toad with a creamy yellow belly and deeply-pitted parotid glands exending down the sides.
These glands contain a milky-white substance commonly called "bufotoxin," which the toad uses as a defense against predators.
This toxin (poison) can cause irritation in humans and animals, particularly when the toxin comes in contact with the eyes or mucus membranes.
www.petsmeds.info /PetsMeds_Main/General/Bufo_Toads   (348 words)

 frogweb.org - Articles - Beauty with a Purpose - Figure 3.   (Site not responding. Last check: 2007-10-20)
The warts, for example, are a feature common to the entire family of toads, Bufonidae, and their primary function has is probably something more to do with hydroregulation (prevention of dessication) than to crypsis.
Another interesting thing to note is that toads are notorious for a particularly noxious secretion from their parotoid glands called Bufotoxin, that even in mild doses can induce quite severe ill-effects even in animals as large as humans.
This poison probably discourages a broad suite of predators, though many other seem to be immune to its effects (e.g., monitor lizards, Varanus spp.), which probably explains why this toad adopts a strategy of crypsis rather than aposematism.
frogweb.org /ArticleIllustrationPage.aspx?ArticleIllustrationID=29   (284 words)

 Lecture Discusses Traditional Chinese Medicine - The NIH Record - June 17, 2005
He gave insight into some studies, including examination of huachansu (a bufotoxin excreted from parotid glands of Bufo toads) in preclinical studies at M.D. Anderson and in a phase I clinical study in advanced hepatocellular carcinoma, non-small cell lung cancer and pancreatic cancer at Fudan Cancer Hospital.
Cohen discussed efforts to understand bufotoxin mechanisms of action, as well as quality control for this natural product.
He also discussed some of the acupuncture and bio-behavioral projects administered through the international center and highlighted some unique opportunities that have come about as a result of this partnership.
www.nih.gov /nihrecord/06_17_2005/story11.htm   (266 words)

 Frogs and Toads of Florida
Most toads also have a pair of parotid glands bulging out from behind their eyes.
These glands produce a bufotoxin that protects them from being eaten by most animals.
All toads have these glands, but most are too small to severely affect people and our pets.
edis.ifas.ufl.edu /UW089   (1551 words)

 Invasion Biology Introduced Species Summary Project - Columbia University
When a toad is attacked, its defense is exuding a milky fluid, ("bufotoxin"), from these warts, which act as an irritant to the mucous membranes of the attacker.
Though they have many predators who prey on both adults and tadpoles, females produce so many eggs that this factor is offset.
In addition, adults have the strong defense of the bufotoxin, to which most mammals in non-native areas have not adapted a counter defense.
www.columbia.edu /itc/cerc/danoff-burg/invasion_bio/inv_spp_summ/Bufo_marinus.html   (1327 words)

 Frog Tales
Toads have one special use that puts them apart from frogs: they are a source of strong medicine.
Bufotoxin taken from a bump on a toad's skin is said to bring on psychedelic hallucinations.
"Liu Hai's toad could transport you anywhere," Aldridge says, and speculates that bufotoxin may have been used by Chinese mystics during vision-seeking rituals.
alumnus.caltech.edu /~pamlogan/frog.html   (754 words)

 Florida's frogs and toads   (Site not responding. Last check: 2007-10-20)
Toads also have a pair of glands that bulge out from behind their eyes.
These glands produce a bufotoxin or poison that protects them from being eaten by most animals.
All toads possess these glands, but most are too small to severely affect people or their pets when they accidentally or playfully come across them.
osceola.ifas.ufl.edu /mg/pl101302.htm   (671 words)

 Giant Toads (Cane Toads) in the Yucatan, Mexico   (Site not responding. Last check: 2007-10-20)
This milky stuff, called bufotoxin, is toxic enough to burn the eyes, inflame skin if it's not washed off, and a good dose of it can kill a dog or a cat.
He said he'd never heard of any problem at all with them, but that he's seen dogs die after chomping down on another toad species we have here, about the same size as our US toads.
Well, all the toads I know of produce bufotoxin to some degree or another, and it sounds like Mexican dogs have more sense than to bite a Giant Toad, but not enough sence to not bite a little toad.
www.backyardnature.net /yucatan/toad-gnt.htm   (476 words)

 LiveScience.com - Invasive Strategy: Toads Hit the Road   (Site not responding. Last check: 2007-10-20)
The toads can grow as large as dinner plates and can weigh up to 4.5 pounds.
Their heads and backsides are studded with rows of warts that secrete a milky white toxin called bufotoxin, which has been known to kill snakes, lizards and other animals, including pet dogs.
To track the creatures' movements, the researchers strapped radio-tracking devices around the waists of 49 adult toads before releasing them into a test area containing regions of densely packed vegetation as well as more open areas near roads and fences.
www.livescience.com /animalworld/060717_toad_roads.html   (484 words)

bufotoxin is one of the topics in focus at Global Oneness.
Bufotenin, also spelled bufotenine, is also known under the names 5-hydroxy-DMT (5-OH-DMT) or dimethyl-serotonin and is a tryptamine related to the neurotransmitter serotonin.
Please rate this archive with 10 as very good and 1 as very poor.
www.experiencefestival.com /bufotoxin   (704 words)

 bufotoxin - OneLook Dictionary Search
We found 4 dictionaries with English definitions that include the word bufotoxin:
Tip: Click on the first link on a line below to go directly to a page where "bufotoxin" is defined.
bufotoxin : Dorland's Illustrated Medical Dictionary [home, info]
onelook.com /?w=bufotoxin   (76 words)

 Journal - 1/11/97
So I was like gonna write this whole thing about the uses of bufotoxin - the poison excreted through the skin of toads (Bufo bufo).
It had lots of interesting things about bufotoxin.
Odd coincidence since I had already written today's title with Anuran in it thinking that bufotoxin was the next logical postfeminist body fluid (anuran is tailless amphibian - that is frogs and toads).
world.std.com /~jegan/0111.html   (1015 words)

 Woodhouse's Toad
They can also survive higher temperatures than similar toads.
ยท Woodhouse's Toads secrete a chemical called Bufotoxin from their shoulder glands.
This toxin is irritating to mucus membranes, and causes an increase in heart rate if it reaches the bloodstream.
www.garden-city.org /zoo/animalinfo/ReptAmph/woodhouses_toad.htm   (349 words)

 McCann Book Chapter 7
If bitten, the toads release milky bufotoxin from the parotoid glands that makes pets ill; however, cats and dogs learn to avoid this noxious species after only one encounter (Ashton and Ashton 1988).
Although wildlife in southern Florida usually does not prey on this species, Garrett and Boyer (1993) saw an opossum Didelphis marsupialis attack and possibly eat this toad even after it had a reaction to the bufotoxin.
However, Ashton and Ashton (1988) believe that the marine toad is harmless and makes a good pet.
aquat1.ifas.ufl.edu /mcamphib.html   (1947 words)

 ChemWiki - Recent changes [en]   (Site not responding. Last check: 2007-10-20)
Interestingly, many species of birds are insensitive to both gingerol and zingerone in concentrations up to 10,000ppm.
It may well be the same one because I found out that some toads have the same bufotoxins, its just that you mentioned a different species (Bufo Americus) and I thought it may be about a different bufotoxin.
If you find that it is about a different bufotoxin, then you could create a new title under Bufotoxins in general, or add a link to a separate page (e.g.
www.ch.ic.ac.uk /wiki/index.php?title=Special:Recentchanges&days=3&limit=500&feed=atom   (4184 words)

 Emory Magazine | In Brief: Program in Science and Society
James sent her sample to the U.S. Centers for Disease Control and Prevention, where its chemical characteristics will be compared to the composition of a toxin stored in the glands of the Central American toad Bufo marinus.
That substance, bufotoxin, is poisonous to other animals but hallucinogenic to humans, so its presence in James’ residue sample would indicate that the pot probably served a ritualistic function.
An undergraduate internship funded by the College’s new Program in Science and Society helped James take part in the collaborative art history/geosciences project.
www.emory.edu /EMORY_MAGAZINE/fall99/science_society.html   (571 words)

 NEWS Release October 1, 2002, 4:00 PM (ET)
But the researchers noted that the studies they evaluated were "of generally poor quality" so they could not make firm conclusions from their findings.
They suggest studying Chinese herbal medicine, particularly those with the active ingredients kurorinone and bufotoxin, as powerful co-treatments with the traditionally used interferon alpha when treating hepatitis B.
The disease is a chronic public health problem, infecting an estimated 2 billion people worldwide.
www.ajph.org /news/archive/2002.10.01.shtml   (886 words)

 Zoo 430L Safety
This is important because some animal tissue or fluid may carry pathogens.
Furthermore, the toad (Bufo marinus) secretes a neurotoxin called Bufotoxin through it's skin.
Gloves are also important to wear when working with toxic chemicals like amiloride, ouabain, cyanide, atropine, and the hormones.
www2.hawaii.edu /~aslamkha/safety.html   (273 words)

 Animal Planet :: News :: Toxic Toads Evolving Quickly
Description: Olive-brown skin on top with cream spots; whitish-yellow underneath; back and legs covered with spiny warts; horizontal pupils.
Cool Facts: It can squirt a white, viscous venom from two poison-filled sacs just behind its head; the venom contains bufotoxin, which causes temporary paralysis and death in small predators.
Use our Sitemap to find what you need quickly.
animal.discovery.com /news/briefs/20060213/toad_02.html   (426 words)

 More info on - bufotoxin
Here's our top rated Bufotoxin links for the day:
As an extra bonus here are the top searched terms over the past month for Bufotoxin.
Now you can see what everyone else is searching for in regards to Bufotoxin.
www.eduwho.com /Bow-to-Cha/Bufotoxin.php   (179 words)

 FUNCTIONAL FOODNET OCTOBER 3   (Site not responding. Last check: 2007-10-20)
specifically looked at bufotoxin, an extract from the skin of the toad Bufo
particular, bufotoxin combined with interferon alfa was significantly more
"Bufotoxin and kurorinone have been singled out as having
archives.foodsafetynetwork.ca /ffnet/2002/10-2002/functional_foodnet_october_3.htm   (1557 words)

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