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Topic: Bunyaviridae

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Virus classification

Morphology

Encephalitis

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	CRORA : RESUME DES PUBLICATIONS
		As will be discussed later the Bunyaviridae have the capacity for sudden dramatic variation comparable to the antigenic shift associated with influenza viruses and thus warrant continual surveillance.
		The criteria for inclusion in the family Bunyaviridae are the following : virus particles are spherical, 99-100 nm in diameter and enveloped with glycoprotein surface projections ; the virions contain three unique segments of negative-sense single-stranded RNA in the form of cIrcular ribonucleoprotein complexes (nucleocapsids) and a transcriptase enzyme.
		Our knowledge of the molecular biology of the Bunyaviridae has expanded rapidly over the last few vears revealing the different coding strategies used by individual genome segments and providing some clues about the evolutionary relationships between the viruses, but these data are far from complete.
	www.pasteur.fr /recherche/banques/CRORA/res1/re160.htm (763 words)

	Bunyaviridae - Wikipedia, the free encyclopedia
		Bunyaviridae are single-stranded RNA viruses with negative polarity, the genome is circular with the size around 11-19 kbp.
		Bunyaviridae can be also called vector-borne virus, which is the Biosafety level 4 viruses.
		This virus can be transmitted via Mosquitoes, and thus is more common during the summer.
	en.wikipedia.org /wiki/Bunyaviridae (196 words)

	ICTVdB Virus Description - 00.011. Bunyaviridae
		Not shown to be antigenically related to members of other Bunyaviridae genera.
		There are at least 7 groups (19 viruses) and 21 ungrouped viruses which have not been shown to be antigenically related to members of defined genera of the family Bunyaviridae.
		The Tenuivirus RNA terminal sequences are conserved 3’and 5’ sequences exhibit inverted complementarity; the conserved 3’ sequence, UGUGUUUCAG.., is similar to the consensus Phlebovirus sequence.
	www.ncbi.nlm.nih.gov /ICTVdb/ICTVdB/11000000.htm (1007 words)

	Ophiovirus
		The virion morphology resembles that of the Genus Tenuivirus and the internal nucleocapsid component of members of the Family Bunyaviridae.
		The capsid protein is significantly larger than that of the tenuiviruses or members of the Family Bunyaviridae.
		No nucleotide or amino acid homologies with members of the Family Bunyaviridae or the Genus Tenuivirus have been detected, nor is there any serological relationship with them.
	www.ncbi.nlm.nih.gov /ICTVdb/Ictv/fs_ophio.htm (214 words)

	Bunyaviridae (Site not responding. Last check: 2007-10-13)
		The family of Bunyaviridae exists of a large family of arthropod-borne viruses that occur worldwide.
		With respect to particle morphology and genomic structure, TSWV is quite distinct from all other plant viruses and was therefore originally classified as the sole member of a distinct group, the tomato spotted wilt virus group (Matthews, 1982).
		Based on these molecular data TSWV could be definitely identified as a bunyavirus, and has therefore been classified within the Bunyaviridae as the representative of a newly created genus, the genus Tospovirus (Francki et al., 1991).
	www.dpw.wageningen-ur.nl /viro/research/t_1_1.html (324 words)

	[No title] (Site not responding. Last check: 2007-10-13)
		In contrast, the virus of Equine infectious anaemia of the family Retroviridae is transmitted by insects, the Thogoto-virus of the family Orthomyxoviridae is transmitted by ticks and Orbiviruses of the family Reovirdae are transmitted by Culicoides and ticks.
		Viruses of the family Arenaviridae and Hantaviruses of the family Bunyaviridae are transmitted by rodents and are therefore termed Roboviruses (rodent-borne viruses).
		Viruses of the family Bunyaviridae, Flaviviridae, and Togaviridae are transmitted mostly by arthropods (Arboviruses).
	www.vetmed.uni-muenchen.de /english/research/dissertations/promotion/ws01-02/WendeC.txt (402 words)

	All the Virology on the WWW - Specific Viruses (A-E)
		Bunyaviridae - Taxonomy, properties and images from the Universal Virus Database, authorised by ICTV (International Committee on Taxonomy of Viruses) which has developed a universal taxonomic scheme for viruses.
		The goal of the ICTVdB is to describe all viruses of animals (vertebrates, invertebrates, protozoa), plants (higher plants and algae), bacteria, fungi, and archaea from the family level down to strains and isolates.
		Bunyaviridae - From the Institute for Molecular Virology, a research institute devoted to fundamental research in virology at the University of Wisconsin, Madison.
	www.tulane.edu /~dmsander/garryfavweb11.html (5562 words)

	Ebola Virus Haemorrhagic Fever
		CCHF virus is placed in the family Bunyaviridae even though few of the properties required for inclusion in the family are known for the virus.
		Additional properties required for inclusion in the Bunyaviridae have not been reported for the virus: RNA in 3 or 4 segments with a total molecular weight of 6 x 10^6 daltons; helical symmetry of the nucleocapsid; presence of at least 3 polypeptides of which 2 are glycopeptides and located in the envelope.
		Exhaustive and continued efforts by hemagglutination inhibition (HI), complementfixation (CF) and agar gel diffusion and precipitation (AGDP) tests have shown the virus to be antigenically related to no other viruses except: to Hazara with which it constitutes the CCHF group, Table 1; and possibly to Nairobi sheep disease (NSD), Tables 2 and 3.
	www.itg.be /ebola/ebola-51.htm (4199 words)

	Manual of Diagnostic Tests and Vaccines for Terrestrial Animals, 5th edition, 2004
		Nairobi sheep disease (NSD) is caused by a Nairovirus of the family Bunyaviridae; it is a tick-transmitted disease that is not contagious.
		It is a member of the Bunyamwera serogroup of the Bunyavirus genus, family Bunyaviridae and is also the most common of the Bunyaviruses of North America (2).
		NSD is a disease of sheep and goats caused by a Nairovirus of the family Bunyaviridae (8).
	www.oie.int /eng/normes/mmanual/A_00128.htm (7021 words)

	Mutational Analysis of the Uukuniemi Virus (Bunyaviridae Family) Promoter Reveals Two Elements of Functional Importance ...
		Secondary structure predictions of the highly conserved terminal regions of the genome segments of members of the five Bunyaviridae genera and the Tenuiviruses in comparison to the corkscrew structure of the influenza A virus vRNA segment promoter.
		In four genera of the Bunyaviridae family, the terminal nucleotides of the RNA genome segments (vRNA and cRNA) can theoretically form intrastrand stem-loop structures, referred to as the corkscrew configuration.
		The model is based on the experimentally proven promoter structure of the influenza A (9, 10, 25, 26) and C (3) viruses and the thogoto (24, 47) virus.
	jvi.asm.org /cgi/content/full/76/21/10849 (7541 words)

	Morphology of the Hantavirus, including structure, symptoms and prevention
		Bunyaviridae Family: Spherical in shape, 90-120 NM in dia.
		Hantavirus is not transmitted through person-to-person contact, though evidence supports the spread of other Bunyaviridae viruses through venereal transmission.
		Hantavirus is not a disease limited to a specific age, race, ethnic group or gender.
	www.rhodes.edu /biology/glindquester/viruses/pagespass/hanta/hanta.htm (1636 words)

	[No title] (Site not responding. Last check: 2007-10-13)
		As with animal viruses, these plant viruses are thought to enter the cells of their animal vectors via the recognition of virus-binding proteins, or putative viral receptors.
		First established in 1980, the Bunyaviridae family includes five genera: Bunyavirus, Hantavirus, Nairovirus, Phlebovirus and Tospovirus, encompassing some of the most dangerous of the emergent group of pathogens.
		With the exception of the hantaviruses, which are transmitted by rodents excreta aerosols, all other members of the Bunyaviridae are transmitted by arthropods (mosquitos, sand flies, ticks, and thrips).
	www.wipo.int /cgi-pct/guest/getbykey5?KEY=01/11090.021107&ELEMENT_SET=DECL (6911 words)

	[No title]
		This web page will give you a sense of the history behind Bunyaviridae, including important epidemics and crucial discoveries.
		It was assumed that Rift Valley Fever was a nonfatal disease until an epidemic of patients in Africa lead to some cases of fatal hemmoraghic fever.
		The biochemical and molecular similarities within the Bunyamwera supergroup were enough to create the family, Bunyaviridae.
	www.stanford.edu /group/virus/1999/arthic/history.html (573 words)

	Bunyavirus and Arenavirus Review Notes
		Bunyaviridae are enveloped viruses. They contain G1 and G2 glycoproteins in the envelope.
		Bunyaviridae have 3 segments of negative sense single-stranded, circular RNA.
		The switch from translation to replication is caused by N protein binding to viral RNA, preventing cap incorporation.
	www.ratsteachmicro.com /Arena_Bunya_notes/HCOE_CAI_Review_Notes_Arena_Bunya.htm (1221 words)

	Annual report of Molecular Genetics of Bunyaviridae for year 2002
		The aim is to identify determinants of virulence, to decipher their mode of action and to produce an attenuated virus which could be utilized as a vaccin candidate.
		Rift Valley fever virus is an arbovirus of the Bunyaviridae family (Phlebovirus genus) transmitted by mosquitoes.
		Plasmids carrying the S-CAT, M-CAT and L-CAT sequences were constructed and these genome-like RNAs were efficiently recognized and transcribed by the viral complex composed of the L polymerase and the N nucleoprotein.
	www.pasteur.fr /recherche/RAR/RAR2002/Gmbun-en.html (388 words)

	Virology -
		My major research effort concerns the Bunyaviridae, a large family of mainly arthropod transmitted viruses which contain a tripartite single-stranded RNA genome of negative- or ambi-sense polarity.
		In addition these viruses present a convenient model to study the assembly processes of segmented genome viruses and intracellular protein targetting to the Golgi.
		The emphasis of the research has been on the molecular characterization of the viral genome segments and their expression, and on functional analysis of the viral proteins.
	www.gla.ac.uk /ibls/virology/research/elliott (375 words)

	hps
		The hantavirus belongs to the bunyaviridae family of viruses and is the worldwide etiological agent for a hemorrhagic fever type illness known as Hemorrhagic Pulmonary Syndrome (HPS).
		The bunyaviridae family consists of five genera: bunyavirus, phlebovirus, nairovirus, tospovirus, and hantavirus.
		All five genera are negative-sense single stranded RNA viruses with an arthropodal vector except for hantavirus, which is rodent borne.
	www.austincc.edu /microbio/2704j/hps.htm (1419 words)

	Rapid Detection of Human Pathogenic Orthobunyaviruses -- Weidmann et al. 41 (7): 3299 -- Journal of Clinical ...
		The Bunyaviridae family of viruses is subdivided into five genera.
		Circulation of viruses of the California serocomplex (Bunyaviridae, Bunyavirus) in the central and southern parts of the Russian plain.
		Isolation of viruses of antigenic complexes of California encephalitis and Bunyamwera (Bunyaviridae, Bunuavirus) from mosquitoes in northeast Asia.
	jcm.asm.org /cgi/content/full/41/7/3299 (3996 words)

	pappataci fever -- Encyclopædia Britannica
		It is transmitted to humans by the bloodsucking female sand fly (notably Phlebotomus papatasii, P. perniciosus, and P. perfiliewsi) and is prevalent in the moist subtropical countries of the Eastern Hemisphere lying between latitude 20° and 45° N,...
		Fact sheet on the disease caused by the RVF virus, a member of the family Bunyaviridae.
		Includes information on the geographic distribution of Rift Valley fever, transmission of the disease to humans, populations who are most at risk, symptoms, treatment, permanent vision loss associated with the disease, and preventive measures.
	www.britannica.com /eb/article-9058347 (751 words)

	Reverse Genetics System for Uukuniemi Virus (Bunyaviridae): RNA Polymerase I-Catalyzed Expression of Chimeric Viral ...
		In this study, we have successfully adopted the RNA pol I transcription system (30, 31, 49) for the development of a
		The S segment of Rift Valley fever phlebovirus (Bunyaviridae) carries determinants for attenuation and virulence in mice.
		Flick, K., Katz, A., Overby, A., Feldmann, H., Pettersson, R. F., Flick, R. Functional Analysis of the Noncoding Regions of the Uukuniemi Virus (Bunyaviridae) RNA Segments.
	jvi.asm.org /cgi/content/full/75/4/1643 (7117 words)

	Hantavirus: Description, Vector, Mechanisms, Symptoms, etc.
		Hantaviruses are biologically unique members of the largest animal virus family, Bunyaviridae.
		Like other Bunyaviridae, hantaviruses have three genomic segments: large, medium, and small; and segment reassortment within a species appears common.
		Also in contrast to other Bunyaviridae, hantaviruses do not appear to have an arthropod vector.
	www.tarakharper.com /v_hanta.htm (1957 words)

	Simbu virus Terms and Definitions at www.MedicalGlossary.org
		Home > Organisms > Viruses > RNA Viruses > Bunyaviridae > Bunyavirus > Simbu virus Terms and Definitions
		A species in the BUNYAVIRUS genus of the family BUNYAVIRIDAE family.
		Previously a large group of serotypes, most are now considered separate species.
	www.medicalglossary.org /bunyavirus_simbu_virus_definitions.html (132 words)

	00.011. Bunyaviridae
		Bishop, D. Bunyaviridae and their replication, Part I. In: B. N., Fields, and D. M., Knipe, (eds), Virology 2nd edn.
		Elliott, R. M., Schmaljohn, C. and Collett, M. Bunyaviridae genome structure and gene expression.
		Schmaljohn, C. and Patterson, J. Bunyaviridae and their replication.
	phene.cpmc.columbia.edu /Ictv/rf_bunya.htm (180 words)

	A structural and primary sequence comparison of the viral RNA-dependent RNA polymerases -- Bruenn 31 (7): 1821 -- ...
		Picornaviridae and Togaviridae are positive strand RNA viruses; Bunyaviridae are negative strand RNA viruses; and Totiviridae are dsRNA viruses.
		PILEUP was run with a similarity matrix of Blosum30 for the Totiviridae and the Bunyaviridae and Blosum62 for both the Picornaviridae- and Togaviridae-related RdRps.
		Gap weight was set at 5 and gap length weight at 1 for the Bunyaviridae, gap weight at 8 and gap length weight at 1 for the Totiviridae, and at the default values otherwise (gap weight at 8 and gap length weight at 2 for Blosum62 and at 15 and 5 for Blosum30).
	nar.oxfordjournals.org /cgi/content/full/31/7/1821 (5700 words)

	APSnet Education Center - Plant Disease Lessons - Tomato spotted wilt (Site not responding. Last check: 2007-10-13)
		The "spotted wilt" disease of tomato was first described in Australia in 1915 and was determined to be of viral etiology in 1930 (
		The Tomato spotted wilt virus (genus Tospovirus; family Bunyaviridae) (TSWV) was thought to be the sole member of the tomato spotted wilt virus group until 1989 when Impatiens necrotic spot virus was characterized.
		The genus Tospovirus now contains TSWV as the type member and more than a dozen other distinct viruses whose identification has been facilitated by the use of serological and molecular techniques.
	www.apsnet.org /education/LessonsPlantPath/TomatoSpottedWilt (167 words)

	CRZEE - Extended Abstracts
		Crimean Congo hemorrhagic fever virus (CCHFV) belongs to the genus Nairovirus within the family Bunyaviridae and is the causative agent of severe hemorrhagic fever.
		The factors determining the virulence and pathogencity among the members of the Bunyaviridae family are poorly understood.
		Innate immunity, which is rapidly activated by many viral infections, is expected to play a predominant role in controlling the initial events of the infections.
	www.zooeco.org /zooeco/soczee/meetings/CRZEE/abstracts.asp?auth=mirazimi_ali (780 words)

	Viral genetic determinants for thrips transmission of Tomato spotted wilt virus -- Sin et al. 102 (14): 5168 -- ...
		Four of the five genera in the Bunyaviridae are transmitted
		Bunyaviridae) in the mosquito vector cosegregate with the medium
		TSWV is a plant-infecting Tospovirus in the family Bunyaviridae.
	www.pnas.org /cgi/content/full/102/14/5168 (4074 words)

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