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Topic: Bupropion

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	Bupropion - Encyclopedia, History, Geography and Biography
		Bupropion is both a dopamine reuptake inhibitor and a norepinephrine reuptake inhibitor.
		Bupropion was first synthesized by Burroughs Research in 1966, and patented by Burroughs-Wellcome (later Glaxo-Wellcome, and, as of 2000, GlaxoSmithKline) in 1974.
		Bupropion has also been shown to act as an competitive α3β4 nicotinic antagonist, the α3β4-antagonism has been shown to interrupt addiction in studies of other drugs such as ibogaine.
	www.arikah.net /encyclopedia/Bupropion (1942 words)

	BUPROPION
		Bupropion is a pharmacologically unique antidepressant, with structural similarities to amphetamines and diethylpropion.
		Bupropion was voluntarily withdrawn from marketing due to the potential for seizures in 1986, and re-introduced in July, 1989.
		Bupropion is an antidepressant and is approved as an aid in smoking cessation (Sigg, 1999) and in the treatment of bulimia (Ayers and Tobias, 2001).
	www.antidepressantsfacts.com /wellbutrin.htm (3117 words)

	Bupropion Information on Healthline
		Bupropion is an antidepressant drug used to elevate mood and promote recovery of a normal range of emotions in patients with depressive disorders.
		Bupropion was one of the first antidepressants with a significantly different chemical structure to be developed by pharmaceutical researchers seeking drugs effective in treating depression but without the unwanted actions of the tricyclic antidepressants.
		Bupropion should not be administered along with other medications that lower the seizure threshold, such as steroids and the asthma medication theophylline.
	www.healthline.com /galecontent/bupropion (1020 words)

	Anxiety Zone - Bupropion
		Bupropion (amfebutamone) is an antidepressant of the aminoketone class, chemically unrelated to tricyclics or SSRIs.
		Bupropion was first synthesized by Burroughs Research in 1966, and patented by Burroughs-Wellcome (later Glaxo-Wellcome) in 1974.
		The actual mechanism behind bupropion's action is not known, but it is thought to be due to the effects on dopaminergic and noradrenergic mechanisms.
	www.anxietyzone.com /drugs/bupropion.html (492 words)

	Bupropion, Wellbutrin Pharmacology - HealthyPlace.com
		Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine, serotonin, and dopamine, and does not inhibit monoamine oxidase.
		However, bupropion was associated with a rise in supine blood pressure in the study of patients with CHF, resulting in discontinuation of treatment in 2 patients for exacerbation of baseline hypertension.
		Bupropion is extensively metabolized in the liver to active metabolites, which are further metabolized and subsequently excreted by the kidneys.
	www.concernedcounseling.com /medications/bupropion.asp (8131 words)

	Bupropion hydrochloride (Zyban) for quitting smoking - [Medication]
		Bupropion is approved for use in people who smoke 10 or more cigarettes a day and are at least 18 years old.
		Like other treatments, bupropion works best when it is part of a complete smoking cessation program that includes setting a quit date; having a plan in place for dealing with things that make you automatically reach for a cigarette (smoking triggers); and getting support from a health professional, counselor, or support group.
		Bupropion should not be used during pregnancy unless the benefits outweigh the risks and the woman is unable to quit smoking without using medication.
	www.healthwise.org /kbase/topic/detail/drug/aa152176/detail.htm (741 words)

	Erowid Bupropion Vault: Basics
		Bupropion is considered a 'second generation' or 'atypical' anti-depressant because its action is different from the previous generation of psychoactive medications.
		Bupropion is sold both as an antidepressant in the US under the trade name "Wellbutrin" and as an aid for quitting smoking under the trade name "Zyban".
		Bupropion may be dangerous in combination with MAO inhibitors and at least 14 days should elapse after the last dose of an MAOI is taken and the use of bupropion.
	www.erowid.org /pharms/bupropion/bupropion_basics.shtml (972 words)

	Bupropion (Wellbutrin/Zyban)
		Bupropion is the generic name for the drug marketed as "Zyban," which is an anti-depressant.
		One advantage of bupropion is that users begin taking the medication prior to quitting smoking, thereby priming his/her body to deal with the stress of quitting.
		Bupropion may be a good choice for people who prefer an alternative to nicotine replacement, or who have not succeeded on traditional nicotine replacement therapies.
	www.quitnet.com /Library/Guides/NRT/bupropion.jtml (447 words)

	MedlinePlus Drug Information: Bupropion
		Children younger than 18 years of age should not normally take bupropion.If your child's doctor has prescribed bupropion for your child, you should watch his or her behavior very carefully, especially at the beginning of treatment and any time his or her dose is increased or decreased.
		Bupropion is in a class of medications called antidepressants.
		Bupropion is also sometimes used to treat bipolar depression and attention deficit disorder.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a695033.html (1196 words)

	bupropion Consumer Drug Information
		You should not take bupropion if you have epilepsy or a seizure disorder, an eating disorder such as anorexia or bulimia, if you are using a second form of bupropion, or if you have suddenly stopped using alcohol or sedatives.
		Bupropion is used to treat major depressive disorder and seasonal affective disorder.
		Bupropion passes into breast milk and could be harmful to a nursing baby.
	www.drugs.com /MTM/bupropion.html (1927 words)

	Carilion - Bupropion hydrochloride (Zyban) for quitting smoking - [Medication]
		Bupropion may help you avoid gaining weight when you quit smoking, but only for as long as you are taking the medication.
		Treatment with bupropion continues for 7 to 12 weeks after you quit smoking, but you can continue to take it for as long as 6 months to a year.
		Like other treatments, bupropion works best when it is part of a program that includes setting a quit date; having a plan for dealing with things that make you reach for a cigarette (smoking triggers); and getting support from a doctor, counselor, or support group.
	www.carilion.com /kbase/htm/aa15/2176/aa152176.htm (854 words)

	Howstuffworks "Bupropion: A Profile of an Antidepressant Drug"
		Bupropion is used to relieve the symptoms of mental depression in patients who cannot take other medications.
		The exact mechanism of action of bupropion is unknown, but it is thought to relieve depression by altering the concentration of certain chemicals that are necessary for nerve transmission in the brain.
		In high doses, bupropion has caused chromosomal changes in animals, but the effects in humans are unknown.
	health.howstuffworks.com /define-bupropion.htm (856 words)

	Bupropion
		Studies have shown that children and teenagers who take antidepressants ('mood elevators') such as bupropion may be more likely to think about harming or killing themselves or to plan or try to do so than children who do not take antidepressants.
		If your child’s doctor has prescribed bupropion for your child, you should watch his or her behavior very carefully, especially at the beginning of treatment and any time his or her dose is increased or decreased.
		Your child’s doctor will want to see your child often while he or she is taking bupropion, especially at the beginning of his or her treatment.Your child’s doctor may also want to speak with you or your child by telephone from time to time.
	www.safemedication.com /displaydrug.cfm?id=695033 (1073 words)

	Bupropion: new therapy for depression American Family Physician - Find Articles (Site not responding. Last check: 2007-10-08)
		Bupropion: New Therapy for Depression Approximately one person in five suffers an episode of clinically significant depression at some time during his or her life.
		Bupropion is a monocyclic compound with the same basic structure as phenylethylamine, a sympathomimetic amine.
		Bupropion, unlike other antidepressant drugs, has no effect on noradrenergic or serotoninergic transmission and does not block MAO in the brain.
	www.findarticles.com /p/articles/mi_m3225/is_n6_v41/ai_9140809 (786 words)

	NIDA - Publications - NIDA Notes - Vol. 20, No. 5 - Research Findings
		In a NIDA-funded study of smokers with schizophrenia, those who took sustained-release bupropion were more likely to stop smoking by their quit date and to achieve continuous abstinence for a month than those who received placebo, and they also remained abstinent longer.
		Among patients who were not abstinent at the end of the study, those in the bupropion group reduced the average number of cigarettes smoked daily from 34 to 9, compared with a drop from 25 to 15 in the placebo group.
		Bupropion was generally well tolerated and did not exacerbate the symptoms of schizophrenia.
	www.drugabuse.gov /NIDA_notes/NNvol20N5/Bupropion.html (609 words)

	Bupropion (Systemic) - MayoClinic.com (Site not responding. Last check: 2007-10-08)
		Bupropion (byoo-PROE-pee-on) is used to relieve mental depression and is used as part of a support program to help you stop smoking.
		Bupropion must be used with caution in children with depression.
		The amount of bupropion you take may have to be changed often to meet the needs of your condition and to help avoid unwanted effects.
	www.mayoclinic.com /health/drug-information/DR202098 (1634 words)

	Bupropion - Wikipedia, the free encyclopedia
		In 1997, bupropion (as bupropion hydrochloride) was approved by the FDA for use as a smoking cessation aid.
		Bupropion is also being investigated for several other disorders including overweight or obesity, attention-deficit hyperactivity disorder, restless legs syndrome and a possible treatment for increasing sexual functioning in some women.
		The effects of bupropion in treating eleven patients with bipolar or schizoaffective disorder were examined in an open trial.
	en.wikipedia.org /wiki/Bupropion (2137 words)

	Bupropion Information from Drugs.com
		Bupropion can cause seizures in people who drink a lot of alcohol and then suddenly quit drinking when they start using the medication.
		While you are taking bupropion, you will need to be monitored for worsening symptoms of depression and/or suicidal thoughts during the first weeks of treatment, or whenever your dose is changed.
		Bupropion is available with a prescription under the brand names Wellbutrin, Wellbutrin SR, Wellbutrin XL, and Zyban.
	drugs.com /Bupropion.html (2001 words)

	WhatMeds.com - Bupropion
		Wellbutrin is the brand name for Bupropion, a type of antidepressant (aminoketone class) that also acts as a stimulant.
		Bupropion is also used to help people stop smoking.
		When it is prescribed for this reason, it is marketed under the brand name Zyban, which contains a different dosage of Bupropion than drugs used to treat mental disorders, and is prescribed differently.
	www.whatmeds.com /meds/bupropion.html (480 words)

	bupropion (Wellbutrin, Wellbutrin XL) - drug class, medical uses, medication side effects, and drug interactions by ...
		Bupropion is unique in that its major effect is on dopamine, an effect which is not shared by the selective serotonin reuptake inhibitors or SSRIs (e.g.
		PREGNANCY: Although there are no adequate studies of bupropion in pregnant women, studies in pregnant animals using doses much higher than those used in humans, have demonstrated that bupropion is safe.
		Bupropion, therefore, can be used in pregnancy if the physician feels that it is necessary.
	www.medicinenet.com /bupropion/article.htm (928 words)

	Bupropion (Site not responding. Last check: 2007-10-08)
		Bupropion is used to treat people with depression and to aid in smoking cessation treatment.
		A 50-year-old woman who was unresponsive to traditional antidepressant therapy was reported to have a marked and persistent improvement in mood when yohimbine was added to her bupropion therapy.
		However, people taking bupropion who are also attempting to discontinue chronic alcohol consumption have been reported to sometimes experience convulsions.
	www.kroger.com /hn/Drug/Bupropion.htm (339 words)

	Clinical Trial: Effectiveness of Bupropion in Treating Marijuana Dependent Individuals
		Bupropion (Zyban) is a medication currently used to treat withdrawal symptoms associated with tobacco use.
		Bupropion has been shown to be effective in treating nicotine addiction.The purpose of this study is to determine if bupropion is effective in treating marijuana dependent individuals.
		Bupropion will be administered at 150 mg per day for 3 days, followed by 300 mg per day for the remainder of the study.
	www.clinicaltrials.gov /ct/show/NCT00142870 (434 words)

	Bupropion - Patient UK
		Bupropion increases the levels of these chemicals, reducing cravings and withdrawal symptoms.
		Bupropion tablets should be swallowed whole, not crushed or chewed, with a glass of water.
		Bupropion is not recommended in people under 18 years old.
	www.patient.co.uk /showdoc/30003895 (717 words)

	Zyban Online, Description, Chemistry, Ingredients - Bupropion Hcl - RxList Monographs
		ZYBAN (bupropion hydrochloride) Sustained-Release Tablets are a non-nicotine aid to smoking cessation.
		Initially developed and marketed as an antidepressant (WELLBUTRIN [bupropion hydrochloride] Tablets and WELLBUTRIN SR [bupropion hydrochloride] Sustained-Release Tablets), ZYBAN is also chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents.
		Each tablet contains the labeled amount of bupropion hydrochloride and the inactive ingredients carnauba wax, cysteine hydrochloride, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80 and titanium dioxide and is printed with edible fl ink.
	www.rxlist.com /cgi/generic/buprop.htm (366 words)

	Bupropion - Drugs & Vitamins - Drug Library - DrugDigest
		BUPROPION (Wellbutrin®) is an antidepressant, a medicine that helps to lift mental depression.
		Bupropion acts differently from other antidepressants and may be useful for treating patients who have had unusual or limiting effects from other antidepressants.
		Occasionally bupropion is prescribed for other behavioral or emotional problems.
	www.drugdigest.org /DD/DVH/Uses/0,3915,88\|Bupropion,00.html (844 words)

	BuPROPion
		Data for the immediate-release formulation of bupropion revealed a seizure incidence of 0.4% in patients treated at doses in the 300-450 mg/day range.
		Be aware that bupropion is marketed under different names and should not be taken together; Zyban® is for smoking cessation and Wellbutrin® is for treatment of depression.
		Monitoring of blood pressure is recommended in patients receiving the combination of bupropion and nicotine replacement, particularly in those with hypertension and/or significant coronary artery disease.
	www.musc.edu /pharmacyservices/Drugs/B/Bupropion.htm (1839 words)

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