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Topic: Burkholderia


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  Burkholderia - Wikipedia, the free encyclopedia
Burkholderia is a genus of proteobacteria probably best-known for its pathogenic members - Burkholderia mallei responsible for glanders, a disease that occurs mostly in horses and related animals, Burkholderia pseudomallei - causing agent of melioidosis and Burkholderia cepacia - an important source of pulmonary infection in people with cystic fibrosis.
The usage of Burkholderia in agricultural purposes (as biodegradation and biocontrol means and plant-growth-promoting rhizobacteria) is subject to discussions because of possible pathogenic effects in immuno-compromised people (esp. CF -sufferers), e.g., in-hospital infections.
Due to relative resistance to antibiotics and rather high mortality rate Burkholderia mallei and Burkholderia pseudomallei are sometimes considered as potential biological warfare agents targeting livestock and humans.
en.wikipedia.org /wiki/Burkholderia   (191 words)

  
 DBMD - Glanders - General Information   (Site not responding. Last check: 2007-11-03)
Glanders is an infectious disease that is caused by the bacterium Burkholderia mallei.
Burkholderia mallei is an organism that is associated with infections in laboratory workers because so very few organisms are required to cause disease.
Burkholderia mallei is usually sensitive to tetracyclines, ciprofloxacin, streptomycin, novobiocin, gentamicin, imipenem, ceftrazidime, and the sulfonamides.
www.cdc.gov /ncidod/dbmd/diseaseinfo/glanders_g.htm   (534 words)

  
 GENOME ANALYSIS OF BURKHOLDERIA CEPACIA AC1100
Burkholderia cepacia is an important organism in bioremediation of environmental pollutants and it is also of increasing interest as a human pathogen.
Burkholderia (formerly Pseudomonas) cepacia is important in environmental microbiology and bioremediation of numerous toxic compounds (Lessie and Gaffney, 1986; Bhat et al., 1994; Shields and Reagin, 1992; Shields et al., 1995).
Burkholderia cepacia strains AC1100, which metabolizes 2,4,5-T (Kilbane et al., 1982), and PT88, a transposon induced mutation of AC1100 (Sangodkar et al., 1988), were provided by A. Chakrabarty.
www.nbiap.vt.edu /brarg/brasym95/hendrickson95.htm   (4873 words)

  
 Burkholderia mallei
The causative agent of glanders in the genus Burkholderia is Burkholderia mallei.
Mechanism: Burkholderia mallei cells are transmitted to humans by inhalation of bacteria in aerosols or dust or contact with infected animals.
Pathogenesis Mechanism: Burkholderia mallei pathogenesis is characterized by nodules, abscesses and ulcers in the mucous membranes, skin, lymphatic vessels and/or subcutaneous tissues.
pathport.vbi.vt.edu /pathinfo/pathogens/Burkholderia_mallei.html   (3099 words)

  
 Know your onions: Peeling away the Burkholderia genome
Burkholderia cenocepacia was first isolated in 1949 from rotting onions.
Burkholderia cenocepacia genome sequencing at the Sanger Institute
Burkholderia pseudomallei genome sequencing at the Sanger Institute
www.wellcome.ac.uk /doc_WTX022754.html   (1377 words)

  
 CABRI: HyperCatalogue: Bacteria: all catalogues: Burkholderia cepacia   (Site not responding. Last check: 2007-11-03)
Burkholderia cepacia (Palleroni and Holmes 1981) Yabuuchi et al.
Burkholderia cepacia, (Palleroni and Holmes 1981) Yabuuchi, Kosako, Oyaizu, Yano, Hotta, Hahimoto, Ezaki and Arakawa 1993 VL Bacteria
This work cannot be reproduced in whole or in part without the express written permission of the CABRI consortium.
www.cabri.org /HyperCat/bact/all47.htm   (820 words)

  
 Taxonomy and Identification of the Burkholderia cepacia Complex -- Coenye et al. 39 (10): 3427 -- Journal of Clinical ...
Discrimination of Burkholderia multivorans and Burkholderia vietnamiensis from Burkholderia cepacia genomovars I, III, and IV by PCR.
Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia.
An outbreak of Burkholderia cepacia with septicemia on a cardiology ward.
jcm.asm.org /cgi/content/full/39/10/3427   (5878 words)

  
 Nitrogen Fixation Genes in an Endosymbiotic Burkholderia Strain -- Minerdi et al. 67 (2): 725 -- Applied and ...
ClustalW alignment of the amino acid sequences deduced from the Burkholderia nifH, nifD, and nifK genes and from the A.
Amplification of Burkholderia nif genes from Gigaspora spores.
Identification and characterization of the nif genes in Burkholderia.
aem.asm.org /cgi/content/full/67/2/725   (4814 words)

  
 eMedicine - Burkholderia : Article by Burke A Cunha, MD
Background: Burkholderia cepacia is an aerobic gram-negative bacillus found in a variety of aquatic environments.
Spencer RC: The emergence of epidemic, multiple-antibiotic-resistant Stenotrophomonas (Xanthomonas) maltophilia and Burkholderia (Pseudomonas) cepacia.
Wilsher ML, Kolbe J, Morris AJ, Welch DF: Nosocomial acquisition of Burkholderia gladioli in patients with cystic fibrosis.
www.emedicine.com /med/topic3459.htm   (2184 words)

  
 Bio221 Microbe of the Week
Burkholderia cepacia is a gram-negative rod that is 1.6-3.2
Burkholderia cepacia has the ability to metabolize almost anything available to it, even chlorinated hydrocarbons.
Due to the problems that Burkholderia cepacia can cause, currently the CDC and the EPA has a moratorium against Bc pesticides and herbicides.
web.umr.edu /~microbio/BIO221_2000/Burkholderia_cepacia.html   (364 words)

  
 Infection Control in Cystic Fibrosis -- Saiman and Siegel 17 (1): 57 -- Clinical Microbiology Reviews   (Site not responding. Last check: 2007-11-03)
Burkholderia cepacia genomovar III Is a common plant-associated bacterium.
Burkholderia cepacia complex bacteria from clinical and environmental sources in Italy: genomovar status and distribution of traits related to virulence and transmissibility.
Burkholderia cepacia complex genomovars and pulmonary transplantation outcomes in patients with cystic fibrosis.
cmr.asm.org /cgi/content/full/17/1/57   (7543 words)

  
 DBMD - Melioidosis - General Information
Burkholderia pseudomallei is an organism that has been considered as a potential agent for biological warfare and biological terrorism.
Melioidosis is diagnosed by isolating Burkholderia pseudomallei from the blood, urine, sputum, or skin lesions.
Burkholderia psuedomallei, the organism that causes melioidosis, is usually sensitive to imipenem, penicillin, doxycycline, amoxicillin-clavulanic acid, azlocillin, ceftazidime, ticarcillin-vulanic acid, ceftriaxone, and aztreonam.
www.cdc.gov /ncidod/dbmd/diseaseinfo/melioidosis_g.htm   (859 words)

  
 United States Patent Application: 0030203470   (Site not responding. Last check: 2007-11-03)
Microorganism belonging to a Burkholderia cepacia AIK bacterial strain.
Temperature that the Burkholderia cepacia AIK bacterial strain decompose oil and fat is not particularly limited, but a range between 15.about.45 degrees centigrade is preferable and between 20.about.35 degrees centigrade is more preferable.
That is, the Burkholderia cepacia AIK bacterial strain can decompose oil and fat, even if the oil and fat is in an actual drain system containing a mixture including detergent.
appft1.uspto.gov /netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=/netahtml/PTO/search-bool.html&r=9&f=G&l=50&co1=AND&d=PG01&s1=milord&OS=milord&RS=milord   (5658 words)

  
 Burkholderia spp. Alter Pseudomonas aeruginosa Physiology through Iron Sequestration -- Weaver and Kolter 186 (8): 2376 ...
(A) Burkholderia cells were in the majority and in stationary phase (added at an OD of roughly 1.0 to fusion I cells at an OD of 0.1).
Burkholderia in both the soil and the lungs of CF patients.
Role of ornibactin biosynthesis in the virulence of Burkholderia cepacia : characterization of pvdA, the gene encoding
jb.asm.org /cgi/content/full/186/8/2376   (4853 words)

  
 Mutagenesis of Burkholderia pseudomallei with Tn5-OT182: isolation of motility mutants and molecular characterization ...   (Site not responding. Last check: 2007-11-03)
Mutagenesis of Burkholderia pseudomallei with Tn5-OT182: isolation of motility mutants and molecular characterization of the flagellin structural gene -- DeShazer et al.
Mutagenesis of Burkholderia pseudomallei with Tn5-OT182: isolation of motility mutants and molecular characterization of the flagellin structural gene
Burkholderia pseudomallei is a human and animal pathogen in tropical
intl-jb.asm.org /cgi/content/abstract/179/7/2116   (928 words)

  
 Genomic Diversity of Burkholderia pseudomallei Clinical Isolates: Subtractive Hybridization Reveals a Burkholderia ...
gladioli 5-62 ( 58), Burkholderia uboniae EY 3383 ( 73),
Mutagenesis of Burkholderia pseudomallei with Tn 5 -OT182: isolation of motility mutants and molecular characterization of the flagellin structural gene.
Identification of a Burkholderia mallei polysaccharide gene cluster by subtractive hybridization and demonstration that the encoded capsule is an essential virulence determinant.
jb.asm.org /cgi/content/full/186/12/3938   (5406 words)

  
 Bacteria, gram negative bacilli, non-glucose fermenting
Burkholderia pseudomallei, and Burkholderia mallei finally have been given their own genus name.
Burkholderia mallei causes the disease called glanders.Glanders mainly affects horses, but also in descending order of incidence, donkeys, mules, goats, dogs, and cats can be infected.
Burkholderia, (Pseudomonas) cepacia at Summer Camps for Persons with Cystic Fibrosis, " Pseudomonas cepacia (PC) is a multidrug-resistant, gram-negative bacillus that causes chronic colonization and infection of the respiratory tract of persons with cystic fibrosis (CF).
www.buddycom.com /bacteria/gnr/gnrnogluc.html   (685 words)

  
 Burkholderia cepacia and cystic fibrosis
Although first described in 1949, Burkholderia cepacia has been around for a very long time and it is better to think of this complex of organisms, as emerging pathogens in CF.
Whilst B.cenocepacia and B. multivorans are the most common members of the complex to cause infections and clinical deterioration in patients with cystic fibrosis, all members of the B cepacia complex have been recovered from patients with CF lung disease.
Identification and characterization of a novel DNA marker associated with epidemic Burkholderia cepacia strains recovered from patients with cystic fibrosis.
www.cysticfibrosismedicine.com /htmldocs/CFText/bcepacia.htm   (2423 words)

  
 Burkholderia cepacia Produces a Hemolysin That Is Capable of Inducing Apoptosis and Degranulation of Mammalian ...
Burkholderia cepacia Produces a Hemolysin That Is Capable of Inducing Apoptosis and Degranulation of Mammalian Phagocytes -- Hutchison et al.
Burkholderia cepacia Produces a Hemolysin That Is Capable of Inducing Apoptosis and Degranulation of Mammalian Phagocytes
Burkholderia cepacia is an opportunistic pathogen that has become a major threat to individuals with cystic fibrosis (CF).
iai.asm.org /cgi/content/abstract/66/5/2033   (1003 words)

  
 Improved cultural detection of Burkholderia cepacia from sputum in patients with cystic fibrosis -- Wright et al. 54 ...
Improved cultural detection of Burkholderia cepacia from sputum in patients with cystic fibrosis -- Wright et al.
Burkholderia cepacia, a Gram negative bacillus, is a saprophyte
Burkholderia (Pseudomonas) cepacia and cystic fibrosis: the epidemiology in Belgium.
jcp.bmjjournals.com /cgi/content/full/54/10/803   (1805 words)

  
 David DeShazer, Ph.D.
Burkholderia mallei, the causative agent of glanders, is a gram-negative bacillus.
DeShazer, D., Waag, D.M, Fritz, D.L. and Woods, D.E. Identification of a Burkholderia mallei polysaccharide gene cluster by subtractive hybridization and demonstration that the encoded capsule is an essential virulence determinant.
DeShazer, D. Genomic diversity of Burkholderia pseudomallei clinical isolates: subtractive hybridization reveals a Burkholderia mallei -specific prophage in B. pseudomallei 1026b.
www.daviddeshazer.com   (528 words)

  
 This Month's Feature on APSnet   (Site not responding. Last check: 2007-11-03)
Burkholderia cepacia is a bacterium that is currently attracting considerable attention for its extraordinary versatility as a plant pathogen, saprophyte, biocontrol agent, bioremediation agent, and human pathogen.
In the early 1980’s Burkholderia cepacia became associated with epidemics of severe lung infections ("cepacia syndrome") traced, in many cases, to CF treatment centers and social gatherings where CF patients apparently acquired the disease from other B.
Occurrence of multiple genomovars of Burkholderia cepacia in cystic fibrosis patients and proposal of Burkholderia multivorans sp.
www.apsnet.org /online/feature/BurkholderiaCepacia/Top.html   (1708 words)

  
 Diagnostically and Experimentally Useful Panel of Strains from the Burkholderia cepacia Complex -- Mahenthiralingam et ...
Burkholderia cenocepacia and Burkholderia multivorans: influence on survival in cystic fibrosis.
Baldwin, A., Sokol, P. A., Parkhill, J., Mahenthiralingam, E. The Burkholderia cepacia Epidemic Strain Marker Is Part of a Novel Genomic Island Encoding Both Virulence and Metabolism-Associated Genes in Burkholderia cenocepacia.
GOVAN, J. The Burkholderia cepacia Complex and Cytokine Induction: An Inflammatory Tale.
jcm.asm.org /cgi/content/abstract/38/2/910   (1462 words)

  
 Quorum Sensing in Burkholderia cepacia: Identification of the LuxRI Homologs CepRI -- Lewenza et al. 181 (3): 748 -- ...   (Site not responding. Last check: 2007-11-03)
Quorum Sensing in Burkholderia cepacia: Identification of the LuxRI Homologs CepRI -- Lewenza et al.
Quorum Sensing in Burkholderia cepacia : Identification of the LuxRI Homologs CepRI
Burkholderia cepacia has emerged as an important pathogen in patients with cystic fibrosis.
intl-jb.asm.org /cgi/content/abstract/181/3/748   (1528 words)

  
 Revista do Instituto de Medicina Tropical de São Paulo - Use of selective medium for Burkholderia cepacia ...   (Site not responding. Last check: 2007-11-03)
Burkholderia cepacia, a plant pathogen, was identified in sputum samples from cystic fibrosis patients in the early 80s
cepacia genomovar determination classified two strains as Burkholderia vietnamiensis, two strains as Burkholderia multivorans and 4 strains as belonging to genomovars I or III, as shown in Table 1 and illustrated in Fig.
Pseudomonas cepacia was originally described by Burkholder in 1950 as the causative agent of bacterial rot of onion bulbs.
www.scielo.br /scielo.php?script=sci_arttext&pid=S0036-46652002000400004&lng=es   (3860 words)

  
 Outcome of Burkholderia cepacia colonisation in an adult cystic fibrosis centre -- Ledson et al. 57 (2): 142 -- Thorax
Outcome for patients colonised with Burkholderia cepacia in a Birmingham adult cystic fibrosis clinic at the end of an epidemic.
Burkholderia cepacia colonisation in patients with cystic fibrosis: risk factors and clinical outcome.
Type characterisation and antibiotic susceptibility of Burkholderia (Pseudomonas) cepacia isolates from patients with cystic fibrosis in the UK and the Republic of Ireland.
thorax.bmjjournals.com /cgi/content/full/57/2/142   (2975 words)

  
 International Conference on Burkholderia Pathogenesis - Office of Rare Diseases   (Site not responding. Last check: 2007-11-03)
The objective of the conference was to provide a forum for (1) investigators to present up-to-date research on Burkholderia -related pathogenesis, (2) NIAID staff to outline opportunities to encourage future research, and (3) participants to interact and consider possible research collaborations.
The remaining 8 invited speakers were established leaders from the cystic fibrosis research community, engaged in research on the closely related pathogens Burkholderia cepacia and Pseudomonas aeruginosa.
We were pleased with the high level of researcher interest and participation in the conference and we are confident that the NIAID research portfolio that includes B.
rarediseases.info.nih.gov /html/workshops/workshops/burkholderia20040802.html   (1157 words)

  
 EPA: Federal Register: Burkholderia (Pseudomonas) Cepacia Type Wisconsin; Tolerance Exemption
An exemption from the requirement of a tolerance had been established under 40 CFR 180.1115 for use of the chemical as a seed treatment.
Burkholderia (Pseudomonas) cepacia type Wisconsin applied to plant roots or seedling roots will colonize the developing root system, and by producing antibiotics, protect the seedling or plant from a range of plant pathogenic fungi and nematodes.
The biological pesticide Burkholderia (Pseudomonas) cepacia type Wisconsin is exempted from the requirement of a tolerance in or on all raw agricultural commodities when applied to plant roots and seedling roots, or as a seed treatment for growing agricultural crops [[Page 37022]] in accordance with good agricultural practices.
www.epa.gov /docs/fedrgstr/EPA-PEST/1995/July/Day-19/pr-340.html   (1215 words)

  
 An extracellular zinc metalloprotease gene of Burkholderia cepacia -- Corbett et al. 149 (8): 2263 -- Microbiology
An extracellular zinc metalloprotease gene of Burkholderia cepacia -- Corbett et al.
An extracellular zinc metalloprotease gene of Burkholderia cepacia
Nakazawa, T. and Abe, M. Pathogenesis of Burkholderia cepacia and export of protease by the general secretory pathway involving disulfide bond formation in the periplasm.
mic.sgmjournals.org /cgi/content/full/149/8/2263   (4070 words)

  
 Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations   (Site not responding. Last check: 2007-11-03)
Degradation of chlorobenzenes at nanomolar concentrations by Burkholderia sp.
The utilization of 1,2,4,5-tetrachloro-, 1,2,4-trichloro-, the three isomeric dichlorobenzenes and fructose as the sole carbon and energy sources of nanomolar concentrations was studied in batch experiments with Burkholderia sp.
In liquid culture, all chlorobenzenes were metabolized within 1 h from their initial concentration of 500 nM to below their detection limits of 0.5 nM for 1,2,4,5-tetrachloro- and 1,2,4-trichlorobenzene and 7.5 nM for the three dichlorobenzene isomers, with 63% mineralization during this time.
www.osti.gov /energycitations/product.biblio.jsp?osti_id=354327   (246 words)

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