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Topic: Butyrylcholine


In the News (Thu 31 Dec 09)

  
  Absorbable adhesive compositions - Patent 6620846
The method of claim 1, wherein said polymerization initiator or accelerator is at least one member selected from the group consisting of domiphen bromide, butyrylcholine chloride, benzalkonium bromide, and acetyl choline chloride.
The kit of claim 27, wherein said polymerization initiator or accelerator is at least one member selected from the group consisting of domiphen bromide, butyrylcholine chloride, benzalkonium bromide, and acetyl choline chloride.
The composition of claim 64, wherein said polymerization initiator or accelerator is at least one member selected from the group consisting of domiphen bromide, butyrylcholine chloride, benzalkonium bromide, and acetyl choline chloride.
www.freepatentsonline.com /6620846.html?highlight=5928611   (8586 words)

  
 Acetylcholine - Metabolism - Pharmacorama
Two types of cholinesterases have been distinguished according to their affinities for different substrates, endogenous such as acetylcholine, and exogenous such as acetyl-ß-méthylcholine, butyrylcholine and benzoylcholine.
Acetylcholinesterase, present in nervous tissue and erythrocytes, very quickly hydrolyzes acetylcholine and acetyl-ß-méthylcholine, but does not hydrolyze butyrylcholine.
Butyrylcholinesterase, present in tissues such as heart and plasma, hydrolyzes acetylcholine, benzoylcholine, butyrylcholine but not acetyl-ß-méthylcholine.
www.pharmacorama.com /en/Sections/Acetylcholine_2_1.php   (291 words)

  
 eJIFCC - The Electronic Journal of The IFCC
Concentration, butyrylcholine esterase activity) and prognosis in suicides with organosphosphorus pesticides.
During the period of October 1999-July 2000, 28 patients (men and women) were admitted to the Emergency Service at Ataturk Research and Educational Hospital in Izmir/Turkey due to OP poisoning.
Butyrylcholine esterase activities were determined using butyrylthiocholin as substrate according to the method of Ellman et al, at the Dept. of Biochemistry in Ege University.
www.ifcc.org /ejifcc/vol13no1/1301200104.htm   (594 words)

  
 Succinyl Choline Chloride injection 500mg - Product information :
Prolonged muscular relaxation in surgery can be attained by means of repeated injections of the drug by continuous intravenous drip.
After administration it is rapidly hydrolysed by butyrylcholine esterase of liver and plasma.
Patient who show prolonged apnoea after succinylcholine administration have atypical plasma cholinesterase or deficiency of enzyme due to genetic factor.
www.sgpharma.com /company/products/succinyl.htm   (377 words)

  
 Studies on In Vitro Degradation of Anhydroecgonine Methyl Ester (Methylecgonidine) in Human Plasma   (Site not responding. Last check: 2007-11-03)
It was found that 50% of AEME in human plasma was hydrolyzed to AE within 5 days at room temperature and within 13 days at 4°C. Addition of esterase inhibitors such as sodium fluoride or echothiophate iodide reduced the hydrolysis significantly.
Hydrolysis of AEME also occurred in buffers with pH values above 5, but the hydrolysis rate was significantly lower when compared with plasma and could be markedly increased by the addition of butyrylcholine esterase.
The data suggest that AEME is degraded via two mechanisms: chemical hydrolysis at basic pH and enzymatic hydrolysis by butyrylcholine esterase.
www.jatox.com /abstracts/2002/nov-dec/567-toennes.html   (246 words)

  
 InterPro: IPR000997 Cholinesterase
To prevent continuous firing of nerve impulses, acetylcholinesterase has a high K(cat) (~14000/s), to ensure that acetylcholine is broken down quickly.
Cholinesterases themselves constitute a family of enzymes that fall into two main types, depending on their substrate preference; enzymes that preferentially hydrolyse acetyl esters are termed acetylcholinesterase (AChE) (EC:3.1.1.7); and those that prefer other types of ester, such as butyrylcholine are termed butyrylcholinesterase (BChE) (EC:3.1.1.8).
P06276 Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase)
www.ebi.ac.uk /interpro/IEntry?ac=IPR000997   (3206 words)

  
 Worthington Cholinesterase, Butyryl
It is sometimes referred to as serum cholinesterase as opposed to red cell cholinesterase (AChE).
It hydrolyzes butyrylcholine 4 times more rapidly than acetylcholine.
Kamaric, L.: The Inhibition by D-Tubocurarine of Horse Serum Cholinesterase-Catalyzed Hydrolysis of Butyrylcholine and Benzoylcholine, Biochem Pharmacol 24, 1663, 1975
www.worthington-biochem.com /CHE/default.html   (1867 words)

  
 Genetic mutations of butyrylcholine esterase identified from phenotypic abnormalities in Japan -- Maekawa et al. 43 ...
Genetic mutations of butyrylcholine esterase identified from phenotypic abnormalities in Japan -- Maekawa et al.
Genetic mutations of butyrylcholine esterase identified from phenotypic abnormalities in Japan
We have identified 12 kinds of genetic mutations of butyrylcholine esterase
www.clinchem.org /cgi/content/abstract/43/6/924   (332 words)

  
 Advance Scientific and chemical - , chemical company, chemical compound, spectrum chemical, chemical distributor, ...
For Bulk quotations on "Butyrylcholine Chloride", be sure to contact our Bulk Chemical Department at 1-800-524-2436.
MSDS for Butyrylcholine Chloride, is available upon request.
Advance carries the largest catalog of ACS, Reagent, USP/NF, FCC and technical/commercial chemicals nationwide.
www.advance-scientific.com /Properties.asp?CODE=B3070   (110 words)

  
 The Incidence of T2-Weighted MR Imaging Signal Abnormalities in the Brain of Cocaine-Dependent Patients Is Age-Related ...
Mendal B, Rudney H. Butyrylcholine estrase in the white matter.
Plasma butyrylcholine esterase activity and cocaine half-life differ significantly in rhesus and squirrel monkeys.
Molecular forms of acetylcholinesterase and butyrylcholine esterase in the aged human central nervous system.
www.ajnr.org /cgi/content/full/20/9/1628   (4629 words)

  
 [No title]
Consult the prescribing doctor and read the package insert before using these or any other medications or supplements.
Exelon (rivastigmine) prevents the breakdown of acetylcholine and butyrylcholine (a brain chemical similar to acetylcholine) in the brain.
EXELON is an effective therapy for patients suffering from mild to moderate Alzheimer's disease (AD).
www.angelfire.com /mi4/downs_dementia/Exelon.html   (296 words)

  
 Alzheimer's   (Site not responding. Last check: 2007-11-03)
Razadyne (galantamine) is another medication used in treating mild to moderate AD.
In addition to breaking down acetylcholine in the brain it also breaks down butyrylcholine.
Cholinesterase inhibitor prescribed to treat symptoms of mild to moderate AD 1.5mg, twice a day (3mg/day, available in capsule and liquid form Increase by 3mg/day every 2 weeks to 6mg, twice a day (12mg/day) if well tolerated.
www.memorydr.com /alz.htm   (4065 words)

  
 Alzheimer's Disease Medications Fact Sheet
Some antidepressants such as paroxetine, amitriptyline, fluoxetine, fluvoxamine, and other drugs with anticholinergic action may cause retention of excess Reminyl in the body, leading to complications; NSAIDs should be used with caution in combination with this medication.*
Prevents the breakdown of acetylcholine and butyrylcholine (a brain chemical similar to acetylcholine) in the brain.
Increase by 3mg/day every 2 weeks to 6mg, twice a day (12mg/day).
www.healthieryou.com /alzmeds.html   (655 words)

  
 9.3.5 Depolarizing muscle relaxants
However, blockade can be observed with inhibitors of acetylcholine esterase (see below).
2: This name reflects that the activity of this enzyme used to be assayed with butyrylcholine (I'm not sure if that model substrate is still in use).
However, the enzyme also cleaves acetylcholine and many other natural or synthetic choline esters, just as β-galactosidase cleaves both lactose and many synthetic β-galactosides, including the blue X-Gal that you may have seen in the lab.
watcut.uwaterloo.ca /webnotes/Pharmacology/page-9.3.5.html   (502 words)

  
 C9971 lyophilized powder, ≥2 units/mg
Please select the recommended replacement product below (if a direct replacement is available) or use the links to "similar products" or "related product categories" to see other possible replacement products.
One unit will hydrolyze 1.0 μmole of butyrylcholine to choline and butyrate per min at pH 8.0 at 37 °C. The activity obtained using butyrylcholine as substrate is approx.
Use of this web site constitutes your acceptance of the Site Use Terms
www.sigmaaldrich.com /catalog/search/ProductDetail/SIGMA/C9971   (105 words)

  
 Worthington Cholinesterase, Acetyl
A second cholinesterase found in blood serum hydrolyzes butyrylcholine 4 times faster than acetylcholine.
Enzymatic and immunochemical properties of AChE from electric eel have been reported by Gurari et al.
M and constant enzyme level (approximately optimal for acetylcholine), relative rates of hydrolysis for several esters are: acetylcholine, 100; propionylcholine, 96; butyrylcholine, negligible; and triacetin, 11 (Nachmansohn 1959).
www.worthington-biochem.com /ECH/default.html   (4183 words)

  
 Amazon.com: "squid enzyme": Key Phrase page   (Site not responding. Last check: 2007-11-03)
In regard to substrate specificity, the squid enzyme is similar to acetylcholinesterase.
However, in contrast to the latter, the squid enzyme can split butyrylcholine.
Key Phrases in this book: New York, Cell Biol, Academic Press, Woods Hole, Marine Biological Laboratory, Van Holde, optic lobe synaptosomes, squid neural tissues, gravity receptor systems, teuthoid squids, statoconial layers, squid synaptosomes (See more)
www.amazon.com /phrase/squid-enzyme   (369 words)

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