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	Protein - Wikipedia, the free encyclopedia
		The end of the protein with a free carboxyl group is known as the C-terminus or carboxy terminus, while the end with a free amino group is known as the N-terminus or amino terminus.
		A "tag" consisting of a specific amino acid sequence, usually a series of histidine residues (a "His-tag"), is attached to one terminus of the protein.
		As a result, when the lysate is passed over a chromatography column containing nickel, the histidine residues ligate the nickel and attach to the column while the untagged components of the lysate pass unimpeded.
	en.wikipedia.org /wiki/Protein (5422 words)

	Mutation of Ha-Ras C Terminus Changes Effector Pathway Utilization -- Booden et al. 275 (31): 23559 -- Journal of ...
		from that induced by Ha-Ras61L with the native C terminus.
		of the C terminus of Ext61L to the membrane.
		To study the role of the C terminus in Ha-Ras signaling, both membrane binding and activity must be retained.
	www.jbc.org /cgi/content/full/275/31/23559 (7910 words)

	The C Terminus of the B5 Receptor for Herpes Simplex Virus Contains a Functional Region Important for Infection -- ...
		The C Terminus of the B5 Receptor for Herpes Simplex Virus Contains a Functional Region Important for Infection -- Perez-Romero and Fuller 79 (12): 7431 -- The Journal of Virology
		The C Terminus of the B5 Receptor for Herpes Simplex Virus Contains a Functional Region Important for Infection
		(B and C) Binding of HSV or anti-myc antibody to A7 cells transiently transfected with the indicated myc-tagged plasmid.
	jvi.asm.org /cgi/content/full/79/12/7431 (4590 words)

	Role of the conserved WHXL motif in the C terminus of synaptotagmin in synaptic vesicle docking -- Fukuda et al. 97 ...
		Role of the conserved WHXL motif in the C terminus of synaptotagmin in synaptic vesicle docking -- Fukuda et al.
		Role of the conserved WHXL motif in the C terminus of synaptotagmin in synaptic vesicle docking
		C and are thought to sense a rapid increase in intracellular Ca concentrations (up to 200 µM) (2) via a Ca -dependent phospholipid-binding site (1, 3).
	www.pnas.org /cgi/content/full/97/26/14715 (4018 words)

	Identification of a Tetramerization Domain in the C Terminus of the Vanilloid Receptor -- García-Sanz et al. 24 ...
		The amino acid sequence of the C terminus, along with the secondary structure prediction, is shown at the bottom.
		Blanes-Mira C, Ibañez C, Fernandez-Ballester G, Planells-Cases R, Perez-Paya E, Ferrer-Montiel A (2001) Thermal stabilization of the catalytic domain of botulinum neurotoxin E by phosphorylation of a single tyrosine residue.
		García-Martínez C, Morenilla-Palao C, Planells-Cases R, Merino JM, Ferrer-Montiel A (2000) Identification of an aspartic residue in the P-loop of the Vanilloid receptor that modulates pore properties.
	www.jneurosci.org /cgi/content/full/24/23/5307 (4840 words)

	Functional Evolution of the Photolyase/Cryptochrome Protein Family: Importance of the C Terminus of Mammalian CRY1 for ...
		The photolyase-like domain is shown in dark blue, and the C terminus is shown in light blue.
		Role of the C terminus of mCRY1 in the inhibition of CLOCK/BMAL1-driven transcription.
		The C terminus of mCRY1 is involved in association with mPER1 and mPER2 proteins and therefore regulates the stability and cellular localization of the latter proteins.
	mcb.asm.org /cgi/content/full/26/5/1743 (6056 words)

	Definition of a spliceosome interaction domain in yeast Prp2 ATPase -- EDWALDS-GILBERT et al. 10 (2): 210 -- RNA
		indicating the importance of the C terminus in spliceosome binding.
		Overexpression of the C terminus exacerbated the phenotype
		C protein; * indicates a protein cross-reacted with the anti-histidine-tag antibodies.
	www.rnajournal.org /cgi/content/full/10/2/210 (5449 words)

	The C terminus of the movement protein of Brome mosaic virus controls the requirement for coat protein in cell-to-cell ... (Site not responding. Last check: 2007-10-31)
		The C terminus of the movement protein of Brome mosaic virus controls the requirement for coat protein in cell-to-cell movement and plays a role in long-distance movement -- Takeda et al.
		The C terminus of the movement protein of Brome mosaic virus controls the requirement for coat protein in cell-to-cell movement and plays a role in long-distance movement
		Carvalho, C. M., Wellink, J., Ribeiro, S. G., Goldbach, R. and van Lent, J. The C-terminal region of the movement protein of Cowpea mosaic virus is involved in binding to the large but not to the small coat protein.
	vir.sgmjournals.org /cgi/content/full/85/6/1751 (6072 words)

	Interactive Fly, Drosophila
		The localization of the C terminus of Ephrin was studied.
		If the C terminus is cytoplasmic, the intact membrane should protect the GFP tag, while the extracellular ephrin domain should be destroyed.
		Deletion of the N terminus (aa 1-202) results in a diffuse distribution of the truncated protein in the cytoplasm of S2 cells and embryos (Bossing, 2002).
	www.sdbonline.org /fly/hjmuller/ephrlig3.htm (1360 words)

	Conserved Glycines in the C Terminus of MinC Proteins Are Implicated in Their Functionality as Cell Division Inhibitors ...
		Conserved Glycines in the C Terminus of MinC Proteins Are Implicated in Their Functionality as Cell Division Inhibitors -- Ramirez-Arcos et al.
		Predicted surfaces A, B, and C, as well as turns of the ß-helix of the MinC C terminus, are labeled.
		MinC glycine residues residing in the B-C surface junction of the MinC C terminus are involved in the MinC-MinD interaction.
	jb.asm.org /cgi/content/full/186/9/2841 (5820 words)

	Dual role of the adenovirus pVI C terminus as a nuclear localization signal and activator of the viral protease -- ...
		Dual role of the adenovirus pVI C terminus as a nuclear localization signal and activator of the viral protease -- Honkavuori et al.
		Dual role of the adenovirus pVI C terminus as a nuclear localization signal and activator of the viral protease
		Anderson, C. The proteinase polypeptide of adenovirus serotype 2 virions.
	vir.sgmjournals.org /cgi/content/full/85/11/3367 (4512 words)

	The C Terminus of Peripherin/rds Participates in Rod Outer Segment Targeting and Alignment of Disk Incisures -- Tam et ...
		The C Terminus of Peripherin/rds Participates in Rod Outer Segment Targeting and Alignment of Disk Incisures -- Tam et al.
		XperCT282-346 (A), XperCT297-346 (B), and XperCT307-346 (C) were found throughout the ROS, but exhibited greater affinity for incisures (arrowheads) as indicated by intense longitudinal stripes of fluorescence superimposed over the fainter fluorescence in the disk lamella.
		Chen, C., and Okayama, H. High-efficiency transformation of mammalian cells by plasmid DNA.
	www.molbiolcell.org /cgi/content/full/15/4/2027 (6562 words)

	Rhodopsin C terminus, the site of mutations causing retinal disease, regulates trafficking by binding to ...
		The rhodopsin C-terminal peptide and the GST fusion protein containing the C terminus of rhodopsin specifically bind a 20-kDa protein, a member of the ARF family of small GTPases.
		The UV-activatable crosslinker Br-DAP was attached to the N-terminally biotinylated peptide C, and C
		(C) Retinal PNS was incubated with the biotinylated Br-DAP peptides.
	www.pnas.org /cgi/content/full/102/9/3301 (4589 words)

	Limited and Defined Truncation at the C Terminus Enhances Receptor Binding and Degranulation Activity of the ...
		TG C terminus) to detect the recombinant variants as well as NAP-2-(X) reconfirmed that all these molecules were truncated at the C terminus.
		These findings indicated that the C terminus could be important for the function of the chemokine.
		Dependence of functional activity on the length of the C terminus has also been demonstrated for IL-8, where a synthetic analogue truncated by three residues exhibited slightly enhanced activity, while truncation by six residues abolished this effect(18).
	www.jbc.org /cgi/content/full/270/11/6338 (6508 words)

	A Proline-Rich Motif in the C Terminus of Akt Contributes to Its Localization in the Immunological Synapse -- Kane et ...
		A Proline-Rich Motif in the C Terminus of Akt Contributes to Its Localization in the Immunological Synapse -- Kane et al.
		A Proline-Rich Motif in the C Terminus of Akt Contributes to Its Localization in the Immunological Synapse
		C terminus, however, this region of Akt is insufficient by itself
	www.jimmunol.org /cgi/content/full/172/9/5441 (5767 words)

	The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity -- Huard et al. 31 ...
		The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity
		and that an RT region adjacent to the C terminus of hTERT is
		C terminus, perhaps between residues 963 and 1117.
	nar.oxfordjournals.org /cgi/content/full/31/14/4059 (6001 words)

	Entomology - Peter W. Atkinson (Site not responding. Last check: 2007-10-31)
		Riverside is within 90 minutes drive of the Orange County beaches, San Diego, downtown Los Angeles, the San Gabriel and San Bernardino Mountains, Palm Springs, and the High and Low Deserts of Southern California.
		Arensburger, P., Y.J. Kim, J. Orsetti, C. Aluvihare, D.A. O'Brochta and P.W. Atkinson.
		O’Brochta, D. Sethuramuran, R. Wilson, R. Hice, A. Pinkerton, C.S Levesque, D. Bideshi, N. Jasinskiene, C. Coates, A. James, M. Lehane, and P. Atkinson.
	www.insects.ucr.edu /people/atkinson.html (1769 words)

	Differential Requirement for the Nonhelical Tailpiece and the C Terminus of the Myosin Rod in Caenorhabditis elegans ...
		The C termini of full-length MHC A (fl) and MHC B (gray) are shown as aligned by the program Megalign, with the C termini of mutant and chimeric constructs shown below.
		Dey, C.S., Deitiker, P.R., and Epstein, H.F. Assembly-dependent phosphorylation of myosin and paramyosin of native thick filaments in Caenorhabditis elegans.
		Sohn, R.L., Vikstrom, K.L., Strauss, M., Cohen, C., Szent-Gyorgyi, A.G., and Leinwand, L.A. A 29 residue region of the sarcomeric myosin rod is necessary for filament formation.
	www.molbiolcell.org /cgi/content/full/14/4/1677 (7915 words)

	Phosphorylation of Thr-948 at the C Terminus of the Plasma Membrane H+-ATPase Creates a Binding Site for the Regulatory ...
		Phosphorylation of Thr-948 at the C Terminus of the Plasma Membrane H
		The peptides mimicking the C terminus of the H
		(C) 14-3-3 protein overlay of a protein gel blot corresponding to the one in (B).
	www.plantcell.org /cgi/content/full/11/12/2379 (6348 words)

	External Loops at the C Terminus of Erwinia chrysanthemi Pectate Lyase C Are Required for Species-Specific Secretion ...
		External Loops at the C Terminus of Erwinia chrysanthemi Pectate Lyase C Are Required for Species-Specific Secretion through the Out Type II Pathway -- Lindeberg et al.
		Regions are designated A, B, C, D, and E according to the key at the top.
		Regions A and C and the C-terminal (C-term) branch of region E, none of which are required for species-specific secretion, are indicated in white.
	jb.asm.org /cgi/content/full/180/6/1431 (4644 words)

	Transcriptional repressor CopR: dissection of stabilizing motifs within the C terminus -- Kuhn et al. 147 (12): 3387 -- ...
		the C terminus stabilized CopR (CopR derivative CopVT).
		For the analysis of the structure of mutated C termini, E.
		Kuhn, K., Steinmetzer, K. and Brantl, S. Transcriptional repressor CopR: the structured acidic C terminus is important for protein stability.
	mic.sgmjournals.org /cgi/content/full/147/12/3387 (2411 words)

	Sla1, a Schizosaccharomyces pombe Homolog of the Human La Protein, Induces Ectopic Meiosis when Its C Terminus Is ...
		fused to the C terminus of the genomic sla1
		C or pREP1-Sla1RRM caused the haploid cells to undergo a meiotic catastrophe.
		C acts downstream of Mei3 and upstream of Mei2.
	ec.asm.org /cgi/content/full/2/6/1274 (6158 words)

	Importance of M-Protein C Terminus as Substrate Antigen for Serodetection of Equine Arteritis Virus Infection -- ...
		Importance of M-Protein C Terminus as Substrate Antigen for Serodetection of Equine Arteritis Virus Infection -- Jeronimo and Archambault 9 (3): 698 -- Clinical and Vaccine Immunology
		Importance of M-Protein C Terminus as Substrate Antigen for Serodetection of Equine Arteritis Virus Infection
		C) with the EAV horse antisera, thereby demonstrating the antigenicity
	cdli.asm.org /cgi/content/full/9/3/698 (4324 words)

	Localization of Functional Domains of the Mitogenic Toxin of Pasteurella multocida -- Pullinger et al. 69 (12): 7839 -- ...
		(C to E) Representative fluorescence micrographs of cells microinjected with buffer (C), GST/1-506 (D), and GST/681-C (E) as described in Materials and Methods and stained for rabbit IgG to detect injected cells.
		(C) Effect of KCl buffer and PBS on the activity of 5 ng of PMT/ml.
		Our assignment of catalytic activity to the C terminus of PMT is supported by a very recent publication (2) that showed
	iai.asm.org /cgi/content/full/69/12/7839 (6266 words)

	The carboxyl terminus of the Bacillus subtilis SecA is dispensable for protein secretion and viability -- van Wely et ... (Site not responding. Last check: 2007-10-31)
		The carboxyl terminus of the Bacillus subtilis SecA is dispensable for protein secretion and viability -- van Wely et al.
		C (lanes 3 and 6) was loaded on a glutathione Sepharose column with bound GST (lanes 1–3) or GST-C fusion protein (lanes 4–6), washed, and the bound proteins were eluted with reduced glutathione (a) or EDTA (b).
		Fekkes, P., van der Does, C. and Driessen, A. The molecular chaperone SecB is released from the carboxy-terminus of SecA during initiation of precursor protein translocation.
	mic.sgmjournals.org /cgi/content/full/146/10/2573 (4694 words)

	Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus -- Chauvet et al. 114 (10): ...
		Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus -- Chauvet et al.
		Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus
		(C) Nuclear extracts prepared from the same stably transfected MDCK cells as in B were probed with anti-HA and Mex-46.
	www.jci.org /cgi/content/full/114/10/1433 (7349 words)

	TechRef-166 - ROLE OF THE CONSERVED WHXL MOTIF IN THE C TERMINUS OF SYNAPTOTAGMIN IN SYNAPTIC VESICLE DOCKING.
		TechRef-166 - ROLE OF THE CONSERVED WHXL MOTIF IN THE C TERMINUS OF SYNAPTOTAGMIN IN SYNAPTIC VESICLE DOCKING.
		Synaptotagmin (Syt) I, an abundant synaptic vesicle protein, consists of one transmembrane region, two C2 domains, and a short C terminus.
		Although the short C terminus is highly conserved among the Syt family and across species, little is known about the exact role of the conserved C terminus of Syt I. In this paper, we report a function of the Syt I C terminus in synaptic vesicle docking at the active zones.
	www.glass-bottom-dishes.com /technical/technical-166.html (350 words)

	Effect of MyBP-C Binding to Actin on Contractility in Heart Muscle -- Kulikovskaya et al. 122 (6): 761 -- The Journal ...
		Identification of novel interactions between domains of myosin-binding protein C that are modulated by hypertrophic cardiomyopathy missense mutations.
		Moos, C. Fluorescence microscope study of the binding of added C protein to skeletal muscle myofibrils.
		Mutations in the cardiac myosin binding protein C on chromosome 11 cause familial hypertrophic cardiomyopathy.
	www.jgp.org /cgi/content/full/122/6/761 (8407 words)

	Genetic Analysis Reveals a Role for the C Terminus of the Saccharomyces cerevisiae GTPase Snu114 During Spliceosome ...
		for the C terminus of the protein during spliceosome activation.
		In B and C, serial dilutions were grown on YPD for 8 days at 16° and for 2 days at 25°, 30°, and 37°.
		, C., C. and P., 2002 The ribosomal translocase homologue Snu114p is involved in unwinding U4/U6 RNA during activation of the spliceosome.
	www.genetics.org /cgi/content/full/170/3/1063 (7742 words)

	C Terminal End
		He speculated that the acid terminus has a tyrosine-based sequence internalization signal that interacts with the endocytic adaptor complex to facilitate entry of CFTR into clathrin-coated vesicles.
		Substitution of an alanine residue for tyrosine at position 1424 significantly reduced the ability of AP2 to bind the C terminus of CFTR.
		Taken together, these data suggest that the C terminus of CFTR contains a tyrosine-based internalization signal that interacts with the endocytic adaptor complex AP2 to facilitate efficient entry of CFTR into clathrin-coated vesicles".
	opal.msu.montana.edu /cftr/PointandClick/cftr_point_and_click_cterm.htm (1735 words)

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