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Topic: Cabergoline


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  Cabergoline Official FDA information, side effects and uses.
Cabergoline is moderately bound (40% to 42%) to human plasma proteins in a concentration-independent manner.
Cabergoline tablets are contraindicated in patients with uncontrolled hypertension or known hypersensitivity to ergot derivatives.
Cabergoline is not indicated for the inhibition or suppression of physiologic lactation.
www.drugs.com /pro/cabergoline.html   (2640 words)

  
  MedlinePlus Drug Information: Cabergoline (Systemic)   (Site not responding. Last check: )
Cabergoline (ca-BER-goe-leen) is used to treat different types of medical problems that occur when too much of the hormone prolactin is produced.
Cabergoline use is usually stopped when prolactin levels are normal for 6 months.
Cabergoline should not be used by breast-feeding women or women planning to breast-feed within a short period of time.
www.nlm.nih.gov /medlineplus/druginfo/uspdi/203584.html   (1131 words)

  
 Cabergoline
Because cabergoline is extensively metabolized by the liver, careful monitoring in patients with hepatic impairment is warranted.
Cabergoline is a long acting dopamine receptor agonist with a high affinity for D2 receptors; prolactin secretion by the anterior pituitary is predominantly under hypothalamic inhibitory control exerted through the release of dopamine
Patient should be instructed to notify physician if she suspects she is pregnant, becomes pregnant, or intends to become pregnant during therapy with cabergoline.
www.umm.edu /altmed/drugs/cabergoline-018319.htm   (1101 words)

  
 Cabergoline (Dostinex)
Cabergoline is from the dopaminergic family of drugs that increase the level of dopamine and also decreases the levels of the hormone prolactin.
The study examined cabergoline vs. bromocriptine (Parlodelâ) and proved that cabergoline was superior in all respects to bromicriptine.
Cabergoline’s effects can also be exaggerated when combined with other ergots, including hydergine and nicergoline, particularly those who may be sensitive to them.
www.antiaging-systems.com /a2z/cabergoline_dostinex.htm   (979 words)

  
 CB-Lin (Marketed Products) - Serum Institute of India
Special Populations: The pharmacokinetics of Cabergoline were not altered in patients with moderate to severe renal insufficiency and patients with mild to moderate hepatic dysfunction.
The maximal hypotensive effect of Cabergoline as single dose usually occurs during the first 6 hours after drug intake and is dose dependent both in terms of maximal decrease and frequency.
Cabergoline crosses the placenta in rats: it is unknown whether this occurs in humans.
www.seruminstitute.com /content/products/product_cblin.htm   (1940 words)

  
 Cabergoline versus bromocriptine for levodopa-induced complications in Parkinson's disease
Cabergoline versus bromocriptine for levodopa-induced complications in Parkinson's disease
Cabergoline is a new dopamine agonist recently licensed in the UK for the treatment of later Parkinson's disease.
Cabergoline produces similar benefits to bromocriptine in off time reduction, physical impairment and disability ratings, and levodopa dose reduction over the first three months of therapy.
www.cochrane.org /reviews/en/ab001519.html   (881 words)

  
 MULTIPLE ORGASMS with DOSTINEX + VIAGRA
Cabergoline has an effect on mankind's primary sexual organ, the brain, not on the genitals.
With Cabergoline you can get a pre-orgasm plateau phase of 5 minutes(!) - while under normal, drug-sober conditions, the plateau phase is usually 10 to 20 seconds (the phase during which a man feels that an orgasm may happen certainly, even if all stimulation were stopped).
Cabergoline, as a medication, is as well established for two conditions: Parkinson's disease and excess lactation in women, or lactation in women who have given birth but do not breastfeed.
www.love-drugs.com /cabergoline.html   (848 words)

  
 Cabergoline Shows Significant Advantages Over Pergolide In Parkinson's   (Site not responding. Last check: )
Cabergoline was also better tolerated by patients, more successful in reducing the frequency and severity of dyskinesias, and more convenient to use than pergolide (once-a-day dosing compared to three times-a-day).
Cabergoline can be used for the treatment of Parkinson disease (PD), either as monotherapy in newly diagnosed patients or as adjunctive therapy to levodopa.
Cabergoline is marketed under the brand name Cabaser in Denmark, Finland, Japan, Norway, Sweden, Switzerland and the UK and as Cabaseril in Germany.
www.pslgroup.com /dg/18CC2E.htm   (1085 words)

  
 cabergoline sex - cabergoline sex   (Site not responding. Last check: )
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cabergoline-sex.wow-words.com   (459 words)

  
 Bromocriptine mesylate or cabergoline for infertility - [Medication] - Quest Diagnostics Patient Health Library   (Site not responding. Last check: )
Bromocriptine and cabergoline reduce the body's amount of prolactin, a hormone produced by the pituitary gland.
Bromocriptine or cabergoline may be used when a woman is not ovulating because she has high levels of prolactin in her blood.
Cabergoline causes minimal side effects compared to bromocriptine, but its effects on the fetus are not as fully researched.
www.questdiagnostics.com /kbase/topic/detail/drug/hw202650/detail.htm   (427 words)

  
 Pharmacy Update, November / December 1998   (Site not responding. Last check: )
Cabergoline (Dostinex®) is a new long-acting dopamine agonist that offers the advantage of less frequent dosing and may eventually replace bromocriptine as the agent of choice for the medical management of prolactinomas.
In a multicenter randomized trial comparing the efficacy of cabergoline and bromocriptine, serum prolactin levels were normalized in 83% of patients receiving cabergoline and 58% of patients receiving bromocriptine after 6 months of therapy.
Cabergoline may also be effective in patients who are intolerant of or resistant to bromocriptine.
www.cc.nih.gov /phar/updates/nov-dec98.html   (2353 words)

  
 Cabergoline for levodopa-induced complications in Parkinson's disease
Cabergoline has been compared with inactive placebo in two smaller and shorter (6 - 12 weeks) studies and one larger, medium term trial (24 weeks).
A small but significant advantage of cabergoline over placebo was seen in one study for activities of daily living and physical functioning.
Randomised controlled trials of cabergoline versus placebo in patients with a clinical diagnosis of idiopathic Parkinson's disease and long-term complications of levodopa therapy.
www.cochrane.org /reviews/en/ab001518.html   (852 words)

  
 IngentaConnect Use of the dopamine agonist cabergoline in the treatment of movem...   (Site not responding. Last check: )
Cabergoline is an ergot-derived dopamine agonist used in the treatment of Parkinson’s disease (PD).
Cabergoline has the longest half-life of the dopamine agonists currently available and is effective when given once-daily.
Cabergoline has been shown to be as effective as other dopamine agonists in improving motor function as monotherapy in early PD, and a 5-year levodopa-controlled study indicates the superiority of cabergoline over levodopa in reducing dyskinesias.
www.ingentaconnect.com /content/apl/eop/2002/00000003/00000010/art00011   (310 words)

  
 Cabergoline for RLS   (Site not responding. Last check: )
About 45% of patients treated with cabergoline over five weeks were symptom free, significantly higher than with placebo.
Cabergoline at any dose provided better improvement in RLS symptoms than placebo.
Responders, that is patients without symptoms during the night, comprised 45% with cabergoline at any dose compared with 9% in placebo (Table 1).
www.jr2.ox.ac.uk /bandolier/booth/RLS/caberg.html   (260 words)

  
 Dostinex Official FDA information, side effects and uses.
In the placebo-controlled study (placebo n=20; cabergoline n=168), Dostinex produced a dose-related decrease in serum prolactin levels with prolactin normalized after 4 weeks of treatment in 29%, 76%, 74% and 95% of the patients receiving 0.125, 0.5, 0.75, and 1.0 mg twice weekly respectively.
In the 8-week, double-blind period of the comparative trial with bromocriptine (cabergoline n=223; bromocriptine n=236 in the intent-to-treat analysis), prolactin was normalized in 77% of the patients treated with Dostinex at 0.5 mg twice weekly compared with 59% of those treated with bromocriptine at 2.5 mg twice daily.
Since cabergoline is extensively metabolized by the liver, caution should be used, and careful monitoring exercised, when administering Dostinex to patients with hepatic impairment.
www.drugs.com /pro/dostinex.html   (3118 words)

  
 cabergoline,cabergoline dostinex effects side   (Site not responding. Last check: )
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cabergoline.sunxe.com   (328 words)

  
 Dostinex (Cabergoline) drug description - FDA approved labeling for prescription drugs and medications at RxList
DOSTINEX Tablets contain cabergoline, a dopamine receptor agonist.
The chemical name for cabergoline is 1-[(6-allylergolin-8ß-yl)-carbonyl]-1-[3-(dimethylamino) propyl]-3-ethylurea.
Cabergoline is a white powder soluble in ethyl alcohol, chloroform, and N, N- dimethylformamide (DMF); slightly soluble in 0.1N hydrochloric acid; very slightly soluble in n-hexane; and insoluble in water.
www.rxlist.com /cgi/generic/cabergoline.htm   (116 words)

  
 Cabergoline - A New Dopamine Agonist for the Therapy of Prolactinoma - Neuroendocrine Clinical Center & Pituitary ...
However, cabergoline, a long-acting oral doparnine agonist specific for the D2 receptor, has received the most attention recently, and is currenily the only dopainine agonist being pursued for this indication in the U. The most interesting feature of cabergoline in terms of patient comphance is its extremely long half-life.
Cabergoline was better tolerated than bromocriptine with 3% of women discontinuing cabergoline versus 12% stopping bromocriptine due to intolerance.
In particular, the focus of the study is to determine whether cabergoline is as effective at tumor shrinkage as bromocriptine.
pituitary.mgh.harvard.edu /e-s-962.htm   (820 words)

  
 International Journal of Impotence Research - Abstract of article: Cabergoline treatment in men with psychogenic ...
The effectiveness of cabergoline in 50 men with psychogenic erectile dysfunction was investigated in a 4-month, randomized, placebo-controlled, double-blind study with validated psychological tests, and prolactin, follicle-stimulating hormone, luteinizing hormone and testosterone serum levels.
Cabergoline treatment was well-tolerated and resulted in normalization of hormone levels in most cases.
Cabergoline may be an effective and safe alternative agent for men with psychogenic ED.
dx.doi.org /10.1038/sj.ijir.3901483   (229 words)

  
 ICPD: Long-Term Cabergoline Practical In Elderly With Parkinson’s Disease   (Site not responding. Last check: )
However, he noted, cabergoline may have the potential to avoid some of these effects because of its extremely long half-life of 65 hours.
Contrary to the usual expectations, patients at all ages were essentially equally tolerant of the agonist treatment, with tolerability seen in 85 percent of patients under 65, 80 percent of patients 65-74, and 83 percent of patients 75 and above.
The study presented updated data from the study titled, "The tolerability and efficacy of sustained dopaminergic therapy, using cabergoline mono or adjunctive therapy in 202 elderly and young PD patients: A two-year observational study", supported by industry.
www.pslgroup.com /dg/2021DA.htm   (370 words)

  
 Cabergoline - Drugs & Vitamins - Drug Library - DrugDigest
Cabergoline (Dostinex®) is used to treat high levels of prolactin, a hormone made by the body that affects such things as the menstrual cycle, breast milk production, fertility, and sexual function.
Cabergoline also treats high levels of prolactin which occur with certain tumors such as adenomas.
It may be helpful to take cabergoline with food if you experience nausea, stomach pain, or indigestion after taking it.
www.drugdigest.org /DD/DVH/Uses/0,3915,6068|Cabergoline,00.html   (619 words)

  
 Cabergoline (Systemic)
Cabergoline has not been shown to cause birth defects or other problems in humans.
It is not known whether cabergoline passes into the breast milk.
Studies of this medicine have been done only in adult patients, and there is no specific information comparing use of cabergoline in children with use in other age groups.
allnutritionals.com /drugs/c/cabergoline-systemic.shtml   (1114 words)

  
 DOSTINEX - Prolactin, Hyperprolactinemia - Medical uses (Cabergoline/Cabaser)
“Cabergoline (Dostinex) was shown to be significantly more effective than bromocriptine in inducing a complete biochemical response and clinical efficacy and was better tolerated than bromocriptine in the majority of patients.
Cabergoline can also be useful in the treatment of sleep disturbances associated with advanced Parkinson's disease such as nocturnal akinesia and dystonia.
Cabergoline (Dostinex)can be used as the drug of first choice for arrest of lactation after abortion during the second trimester of pregnancy.”
www.buy-dostinex.com /buy-dostinex/Dostinex_Medical.asp   (1595 words)

  
 Doxtinex (cabergoline) / Cushing's Help and Support
Dostinex (or cabergoline) is a long-lasting, oral dopamine-agonist specific for the D2 receptor indicated for the treatment of hyperprolactinemia.
Comparison of cabergoline and bromocriptine in the treatment of hyperprolactinemic amenorrhea.
Cabergoline: a first-choice treatment in patients with previously untreated prolactin-secreting pituitary adenoma.
www.cushings-help.com /dostinex.htm   (615 words)

  
 cabergoline - [Medication]
Before taking cabergoline, tell your doctor if you are allergic to any drugs, or if you have liver disease, heart disease, or a breathing disorder.
Cabergoline is in a group of drugs called dopamine receptor antagonists.
Cabergoline is used to treat a hormone imbalance in which there is too much prolactin in the blood (also called hyperprolactinemia).
www.peacehealth.org /kbase/multum/d04112a1.htm   (1212 words)

  
 WSAVA 2001 - INDUCED ABORTION IN QUEENS BY ADMINISTRATION OF CABERGOLINE (GALASTOP)
The aim of the present clinical study is to evaluate effectiveness, as well as incidence of adverse side effects, of cabergoline treatment in queens.
The incidence of adverse side effects was rather low and involved 3 queens vomiting after their initial treatment with cabergoline.
Termination of unwanted pregnancies by cabergoline in pregnant queens is effective and safe.
www.vin.com /VINDBPub/SearchPB/Proceedings/PR05000/PR00284.htm   (213 words)

  
 Cabergoline in the Treatment of Hyperprolactinemia: A Study in 455 Patients -- Verhelst et al. 84 (7): 2518 -- Journal ...
Cabergoline in the Treatment of Hyperprolactinemia: A Study in 455 Patients -- Verhelst et al.
Cabergoline [Dostinex (Sostilar in Belgium), Pharmacia & Upjohn,
(5), the median dose of cabergoline was 1.0 mg/week,
jcem.endojournals.org /cgi/content/full/84/7/2518   (3574 words)

  
 Buy Dostinex (Cabergoline Tabets) at Online Canada Pharmacy
Prolactin inhibitors such as Dostinex (Cabergoline) are used to treat different types of medical problems that occur when too much of the hormone prolactin is produced by the pituitary gland, which is found in the brain.
Dostinex (Cabergoline) is also used to prevent the onset of normal lactation (milk production) in cases where there is a medical need to prevent lactation.
High blood pressure caused by pregnancy: Dostinex (Cabergoline) should not be used in women with high blood pressure conditions caused by pregnancy, such as eclampsia or pre-eclampsia, unless the benefit is judged to outweigh the risk.
www.abconlinepharmacy.com /ns/customer/product2197-c-p1   (1689 words)

  
 The Novel Use of Very High Doses of Cabergoline and a Combination of Testosterone and an Aromatase Inhibitor in the ...
Cabergoline doses (in milligrams per week) are indicated by the numbers adjacent to symbols.
The stepwise reduction in PRL levels associated with escalating doses of cabergoline is demonstrated over the first 22 months of dopamine agonist therapy.
9 mg cabergoline in the absence of testosterone and aromatase
jcem.endojournals.org /cgi/content/full/87/10/4447   (3017 words)

  
 NEJM -- Dopamine Agonists and the Risk of Cardiac-Valve Regurgitation
that the ergot-derived dopamine agonists pergolide and cabergoline,
Influence of the Daily Dose of Pergolide or Cabergoline and the Cumulative Duration of Use on the Risk of Cardiac-Valve Regurgitation.
Retrospective evaluation of cardio-pulmonary fibrotic side effects in symptomatic patients from a group of 234 Parkinson's disease patients treated with cabergoline.
content.nejm.org /cgi/content/full/356/1/29   (3806 words)

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