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Topic: Calcinosis cutis

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Dystrophic calcification

Soft tissue

Skin

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	CASE 30—A WOMAN WITH SUBCUTANEOUS MASSES (Site not responding. Last check: 2007-10-29)
		Tumoral calcinosis cutis is a familial syndrome of calcium phosphate deposits in close to the joints, significant hyperphosphatemia and normal serum calcium.
		Metastatic calcinosis cutis is characterized by widespread calcifications in the viscera and elevated serum calcium and phosphorous, and is associated with chronic renal insufficiency.
		Massive dystrophic calcinosis cutis has been described in diabetic patients on insulin, but the lesions are localized to areas of insulin injection, unlike our patient.
	www.med.wayne.edu /dermatology/webmichderm01/case30.htm (574 words)

	NYU SoM - Dept. of Dermatology
		Dystrophic calcification is the most common form of calcinosis cutis and results from local tissue injury or from underlying abnormalities in the tissue.
		Diffuse calcinosis cutis in a patient with congenital leukemia and leukemia cutis.
		Calcinosis cutis as a complication of parenteral calcium gluconate therapy.
	www.med.nyu.edu /dermatology/sem_conf/111803-2.html (779 words)

	De Risio and Olby, Tumoral Calcinosis (Site not responding. Last check: 2007-10-29)
		Calcinosis circumscripta or tumoral calcinosis is a syndrome of ectopic mineralization characterized by deposition of calcium salts (calcium phosphate crystals, including hydroxyapatite crystals) in soft tissues.
		Calcinosis circumscripta of the aorta in a Holstein cow.
		Tumoral calcinosis of the cervical spine in an infant.
	www.neurovet.org /DeRisioandOlby1/Tumoralcalcinosis.htm (3030 words)

	Scleroderma from A to Z: Calcinosis
		Calcinosis is one of the symptoms of CREST Syndrome, which is a form of systemic scleroderma.
		Calcinosis cutis is common in several connective tissue diseases such as dermatomyositis, scleroderma or lupus erythematous.
		Calcinosis cutis circumscripta typically involves the extremities and is associated with prior trauma and scleroderma.
	www.sclero.org /medical/symptoms/skin/calcinosis.html (1766 words)

	eMedicine - Calcinosis Cutis : Article Excerpt by: Julia R Nunley, MD (Site not responding. Last check: 2007-10-29)
		Background: Calcinosis cutis is a term used to describe a group of disorders in which calcium deposits form in the skin.
		Calcinosis cutis is classified into 4 major types according to etiology: dystrophic, metastatic, iatrogenic, and idiopathic.
		The pathogenesis of calcinosis cutis is not completely understood and a variety of factors allow for different clinical scenarios to occur.
	www.emedicine.com /derm/byname/calcinosis-cutis.htm (371 words)

	SiriusDog.com - Calcinosis Cutis, Calcium Circumscripta, Canine Gout
		Calcinosis cutis circumscripta in humans is most often seen as nodules in the skin of the extremities, especially the hands (scleroderma).
		If the calcinosis develops in injured tissue, it could be localized, in which case some have surmised it to be often associated with demodex, TB, staph infection, or granuloma caused by a foreign body such as grit or sand imbedded beneath the skin, or it could be connected with epidermoid cysts or malignant tumors.
		The calcinosis cutis could be widespread, appearing in any or all of the following: skin along the back, armpit, groin, flanks, over bony protuberances such as foot bones and vertebrae, and (reportedly) apocrine (sweat) glands.
	siriusdog.com /articles/calcinosis-calcium-canine-gout.htm (2869 words)

	Emergency Medicine
		The diagnosis is calcinosis cutis, a condition caused by the deposition of calcium phosphate crystals within the skin.
		Calcinosis cutis may be associated with an inflammatory disease, such as acne, and has also been linked to previous dermabrasion.
		Metastatic calcinosis, by contrast, rarely affects the skin and is invariably associated with elevated serum levels of calcium, phosphorus, or both.
	www.emedmag.com /html/pre/dia/09_00.asp (270 words)

	eMedicine - Calcinosis Cutis : Article by Julia R Nunley, MD (via CobWeb/3.1 planetlab2.tamu.edu) (Site not responding. Last check: 2007-10-29)
		Dystrophic calcinosis cutis: Calcification is usually localized to a specific area of tissue damage, though it may be generalized in some disorders.
		Calcinosis cutis circumscripta generally occurs earlier and tends to involve the extremities, whereas calcinosis universalis occurs later and is usually more widespread.
		CT is infrequently used in evaluating calcinosis cutis and primarily used in assessing tumoral calcinosis.
	www.emedicine.com.cob-web.org:8888 /DERM/topic66.htm (4140 words)

	Medscape MEDLINE search: Calcinosis
		BACKGROUND: Calcinosis cutis, a disease characterized by the presence of calcium deposits in the skin, is classified into four types according to etiology: dystrophic, metastatic, iatrogenic and idiopathic.
		An account of the impact of different diagnostic methods of M. Fahr]Bilateral striopallidodentate calcinosis, also known as Fahr's disease, is characterized by symmetric calcifications of the basal ganglia, thalami, dentate nuclei of the cerebellum and white matter of the cerebral hemispheres.
		BACKGROUND: Idiopathic calcinosis cutis of the vulva is a rare condition of unknown etiology.
	search.medscape.com /uslclient/searchMedline.do?queryText=Calcinosis (1036 words)

	Calcinosis cutis associated with systemic blastomycosis in three dogs -- Gortel et al. 35 (5): 368 -- Journal of the ...
		Three dogs treated for systemic blastomycosis with intravenous amphotericin B (one case) or amphotericin B lipid complex (two cases) developed mild to severe calcinosis cutis two to six weeks after the initiation of treatment.
		Abnormalities in serum calcium and phosphorus during treatment for blastomycosis or at the time of diagnosis of calcinosis cutis were slight or absent.
		The calcinosis cutis resolved completely in all three dogs with no (two cases) or only palliative (one case) therapy.
	www.jaaha.org /cgi/content/abstract/35/5/368 (186 words)

	Calcinosis cutis. DermNet NZ (Site not responding. Last check: 2007-10-29)
		This condition commonly occurs in the skin, where it is known as calcinosis cutis or cutaneous calcification.
		Calcinosis cutis is divided into four major types according to the original cause of the symptoms.
		The underlying cause of calcinosis cutis should be identified and treated accordingly.
	www.dermnetnz.org /systemic/calcinosis.html (552 words)

	Iatrogenic calcinosis cutis-a rare differential diagnosis of soft-tissue infection in a neonate: A case report Journal ... (Site not responding. Last check: 2007-10-29)
		Iatrogenic calcinosis cutis presents with similar symptoms and signs; its diagnosis may be easily confused with an infective condition by an unwary orthopaedic surgeon.
		The clinicoradiological diagnosis of this case is iatrogenic calcinosis cutis following intravenous infusion of calcium solution for the management of convulsions.1 Although iatrogenic calcinosis cutis has references in the paediatric and dermatology literature, the majority of orthopaedic surgeons are unaware of this disease.
		The dystrophic variety occurs in damaged or traumatised tissues and the serum calcium/phosphorus ratio is found to be normal.4 The metastatic variety occurs in normal tissues in the presence of a disturbed calcium and/or phosphorus balance.4 The rarest variety is iatrogenic calcinosis cutis.
	www.findarticles.com /p/articles/mi_qa3794/is_200508/ai_n15846552 (821 words)

	Calcinosis cutis -
		Calcinosis cutis (or cutaneous calcification) is a type of calcinosis wherein calcium deposits form in the skin.
		The specific manifestation of calcinosis cutis varies according to the original cause of the symptom.
		A disease is any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person.
	www.medicalgeo.com /Med-Diseases-C---Ch/Calcinosis-cutis.html (157 words)

	[No title] (Site not responding. Last check: 2007-10-29)
		CALCINOSIS CUTIS ----------------------------------------- Regarding therapy for stubborn ulcers 2nd to cryoglobulinemia, and notes calcinosis on bx.
		Well, a funny thing happened on the way to the forum, which is this: an orthopod called me today re an obese patient scheduled for a knee replacement, whose pre-op xray shows subcuticular ca++...somewhat above an area of typical stasis syndrome (inflammatory lipodermatosclerosis, stasis purpura, etc (with a hx of DTP some 40 years back).
		My question is this: is calcinosis cutis known to be a consequence of stasis?
	dermatology.cdlib.org /rxderm-archives/calcinosis-cutis (270 words)

	BDS
		Calcinosis cutis is an uncommon disorder caused by an abnormal deposit of calcium phosphate into the skin.
		Based on the pathogenesis it is classified as idiopathic, metastatic, dystrophic, iatrogenic Calcinosis cutis and sub epidermal calcified nodule.
		Tumoral Calcinosis is an uncommon idiopathic variant of Calcinosis Cutis which can be familial (hyperphosphatemic) or non familial (normophosphatemic).
	www.bangalorederma.com /abst.htm (785 words)

	An unusual cause of a discharging sinus -- 79 (933): 424 -- Postgraduate Medical Journal
		Calcinosis cutis is characterised by the deposition of calcium
		Calcinosis cutis in chronic renal failure diagnosed by fine needle aspiration.
		Regression of calcinosis during diltiazem treatment in juvenile dermatomyositis.
	pmj.bmjjournals.com /cgi/content/full/79/933/424-a (474 words)

	Dystrophic Calcinosis cutis in Subacute Lupus
		Dystrophic calcinosis cutis is known to be associated with various connective tissue disorders but to the best of our knowledge has never been reported in subacute cutaneous lupus erythematosus (SCLE), a distinctive cutaneous subset in the spectrum of lupus erythematosus.
		We report a patient with SCLE who developed calcinosis cutis and had normal serum calcium and phosphorus levels and, interestingly, a normal concentration of blood ionized calcium.
		This latter, which represents the active form in the total amount of blood calcium, is a parameter only rarely assessed in patients with dystrophic calcinosis cutis.
	content.karger.com /ProdukteDB/produkte.asp?Doi=18074 (187 words)

	Severe calcinosis cutis associated with treatment of hypoparathyroidism in a dog -- Schaer et al. 37 (4): 364 -- ...
		Severe calcinosis cutis associated with treatment of hypoparathyroidism in a dog -- Schaer et al.
		Severe calcinosis cutis associated with treatment of hypoparathyroidism in a dog
		The medical evaluation supported the diagnosis of primary hypoparathyroidism, but the subsequent hospital course was complicated by severe calcinosis cutis, which caused extensive skin necrosis and marked debilitation.
	www.jaaha.org /cgi/content/abstract/37/4/364 (170 words)

	Canine Gout
		If the calcinosis develops in injured tissue, it could be localized, in which case some have surmised it to be often associated with demodex, TB, staph infection, or granuloma caused by a foreign body such as grit or sand imbedded beneath the skin, or it could be connected with epidermoid cysts or malignant tumors.
		Association, “found no indication of familial occurrence” in their study of idiopathic calcinosis circumscripta.
		Although foot pad involvement in other breeds may indicate the metastatic variety, localized calcinosis circumscripta and successful surgical removal has been reported in the German Shepherd Dog, so we are very optimistic about that young dog’s recovery.
	www.dogstuff.info /canine_gout.html (1857 words)

	DermAtlas: Online Dermatology Image Library dermatology image,confluent and reticulated papillomatosis (of Gougerot and ... (Site not responding. Last check: 2007-10-29)
		Calcinosis cutis comes in a variety of flavors, this case representing a form a dystrophic calcification.
		Calcium can deposit into the tissues in a variety of settings, leading to calcinosis cutis.
		This is a case of a subepidermal calcified nodule, a lesion commonly found on the extremities and ears of infants, but also occasionally seen in adults.
	www.dermatlas.org /derm/result.cfm?Category=-1595790332 (1001 words)

	idiopathic scrotal calcinosis (Site not responding. Last check: 2007-10-29)
		Scrotal nodules composed of calcium without evidence of a disturbance in calcium or phosphorus metabolism constitute idiopathic scrotal calcinosis.
		This condition is described under calcinosis cutis in most textbooks.
		The calcium deposits are sometimes associated with a granulomatous reaction, but there may be deposits that are not associated with an inflammatory reaction.
	www.bweems.com /idioscrcal.html (144 words)

	Arch Dermatol -- Calcinosis Cutis Complicating Adult-Onset Dermatomyositis, March 2004, Weinel and Callen 140 (3): 365
		Arch Dermatol -- Calcinosis Cutis Complicating Adult-Onset Dermatomyositis, March 2004, Weinel and Callen 140 (3): 365
		Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.
		Calcinosis is a common complication of juvenile dermatomyositis,
	archderm.ama-assn.org /cgi/content/extract/140/3/365 (143 words)

	Indian Journal of Dermatology ...
		Unusual type of dystrophic calcinosis cutis is described in six females in the perimenopausal age group with the lesions in the hip region along with their clinical, biochemical, histological and radiological features.
		This is the first report of dystrophic calcinosis of this kind and can aptly be called idiopathic perimenopausal dystrophic calcinosis cutis.
		Two cases of tuberculosis cutis associated with lymphoedema are presented with clinical and histopathological features.
	www.e-ijd.org /oldsite/oct_dec_98_abstracts.html (1248 words)

	Soft Tissue Calcifications
		The CREST syndrome consists of calcinosis cutis (usually seen under the skin of the hands or wrists), Raynaud's phenomenon, esophageal disorders, sclerodactyly, and telangiectasia.
		Patient with CPPD and chondrocalcinosis of hyaline articular cartilage and meniscal fibrocartilage of knee.
		Tumoral calcinosis is a rare, weird entity of unknown etiology.
	www.rad.washington.edu /mskbook/softtissueca.html (1216 words)

	Early manifestation of calcinosis cutis in pseudohypoparathyroidism type Ia associated with a novel mutation in the ...
		Early manifestation of calcinosis cutis in pseudohypoparathyroidism type Ia associated with a novel mutation in the GNAS gene -- Riepe et al.
		Articles by Riepe, F. Articles by Partsch, C.-J. Early manifestation of calcinosis cutis in pseudohypoparathyroidism type Ia associated with a novel mutation in the GNAS gene
		regarding the frequency of calcinosis in AHO are warranted.
	www.eje-online.org /cgi/content/full/152/4/515 (2604 words)

	Calcinosis Universalis Complicating Juvenile Dermatomyositis: Resolution During Probenecid Therapy -- Eddy et al. 82 ...
		Calcinosis Universalis Complicating Juvenile Dermatomyositis: Resolution During Probenecid Therapy -- Eddy et al.
		of the calcinosis was an improved sense of well-being and a
		1991 Hypercalcemia during the resolution of calcinosis universalis in juvenile dermatomyositis.
	jcem.endojournals.org /cgi/content/full/82/11/3536 (1996 words)

	Calcinosis cutis - Wikipedia, the free encyclopedia
		Calcinosis cutis in a dog with Cushing's syndrome
		In dogs, calcinosis cutis is virtually pathognomonic for Canine Cushing's syndrome.
		Calcinosis may be the results of a variety of causes such as:
	en.wikipedia.org /wiki/Calcinosis_cutis (134 words)

	eMedicine - Calcinosis Cutis : Article by Julia R Nunley, MD (Site not responding. Last check: 2007-10-29)
		Becuwe C, Roth B, Villedieu MH, et al: Milia-like idiopathic calcinosis cutis.
		Larsen MJ, Adcock KA, Satterlee WG: Dermal uptake of technetium-99m MDP in calcinosis cutis.
		Puvabanditsin S, Garrow E, Titapiwatanakun R, et al: Severe calcinosis cutis in an infant.
	www.emedicine.com /derm/topic66.htm (4138 words)

	Indian Association of Dermatologists, Venereologists, & Leprologists (Site not responding. Last check: 2007-10-29)
		Calcinosis Cutis Universalis in Juvenile Dermatomyositis: Dr. Bhavini Lodaya
		Juvenile dermatomyositis is an autoimmune inflammatory injury occurring in striated muscle, skin and blood vessels.
		Calcinosis cutis was first reported in dermatomyositis in 1959 is seen in 74% of juvenile dermatomyositis & 20% of adult DM.
	www.iadvlmaha.org /summ/summ12.html (1551 words)

	MIR Teaching file case bs068 (Site not responding. Last check: 2007-10-29)
		Diagnosis: Soft tissue calcinosis secondary to lupus erythematosus.
		Calcinosis cutis in systemic lupus erythematosus represents dystrophic calcification.
		Dermatomyositis, polymyositis, electrical burns, idiopathic calcinosis universalis, scleroderma, mixed connective tissue disease.
	gamma.wustl.edu /bs068te145.html (345 words)

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