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Topic: Cancer cells


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  Cancer
Rather, evidence is accumulating that cancers arise in precursor cells — stem cells or "progenitor cells" — of the tissue: cells that are dividing by mitosis producing daughter cells that are not yet fully differentiated.
Aneuploidy is one of the hallmarks of cancer cells suggesting that failure of the spindle checkpoint is a major step in the conversion of a normal cell into a cancerous one.
A single cell — perhaps an adult stem cell or progenitor cell — in a tissue suffers a mutation (red line) in a gene involved in the cell cycle, e.g., an oncogene or tumor suppressor gene.
users.rcn.com /jkimball.ma.ultranet/BiologyPages/C/Cancer.html   (1703 words)

  
 [No title]
Leukemia is cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood.
A malignant tumor that is a mixture of carcinoma (cancer of epithelial tissue, which is skin and tissue that lines or covers the internal organs) and sarcoma (cancer of connective tissue, such as bone, cartilage, and fat).
A cancer patient’s T cells (a type of white blood cell) are collected and grown in the laboratory to increase the number of T cells that are able to kill the person’s cancer cells.
www.cancer.gov /dictionary/db_alpha.aspx?expand=c   (6400 words)

  
 National Cancer Institute - Dictionary of Cancer Terms
A malignant tumor that is a mixture of carcinoma (cancer of epithelial tissue, which is skin and tissue that lines or covers the internal organs) and sarcoma (cancer of connective tissue, such as bone, cartilage, and fat).
A cancer patient’s T cells (a type of white blood cell) are collected and grown in the laboratory to increase the number of T cells that are able to kill the person’s cancer cells.
A rare cancer in women of childbearing age in which cancer cells grow in the tissues that are formed in the uterus after conception.
cancer.gov /dictionary/db_alpha.aspx?expand=c   (5899 words)

  
 ACS :: What Is Cancer?
Because cancer cells continue to grow and divide, they are different from normal cells.
Cancer cells often travel to other parts of the body where they begin to grow and replace normal tissue.
When cells from a cancer like breast cancer spread to another organ like the liver, the cancer is still called breast cancer, not liver cancer.
www.cancer.org /docroot/CRI/content/CRI_2_4_1x_What_Is_Cancer_72.asp?sitearea=CRI   (446 words)

  
 Glossary
A cancer of the cervix (the neck of the uterus).
Doctors differentiate the different lymphomas by the type of cell that is involved in the makeup of the tumor.
Cells in the blood that are responsible for clotting.
www.meds.com /glossary.html   (2379 words)

  
 The cancer cell
Cancer cells are different to normal cells in several ways.
So the cancer cell keeps on doubling, regardless of the damage the extra cells cause to the part of the body where the cancer is growing.
Cancer cells can lose the molecules on their surface that keep normal cells in the right place.
www.cancerhelp.org.uk /help/default.asp?page=96   (579 words)

  
 Biphasic Mesothelioma Cancer - Mesothelioma Cancer Cells
Whereas biphasic cancer was once seen in approximately 25% of all mesothelioma cases, it has recently been seen in approximately 46% to 63% of all cases; a significant rise.
A Mixture of Epithelioid and Sarcomatoid Cancer Cells
Because biphasic mesothelioma cancer patients have two very different mesothelioma cellular types associated with their disease, it can be an easier form of cancer to diagnose than either sarcomatoid or epithelioid (two cellular types that can be confused with a variety of other cancers).
www.allaboutmalignantmesothelioma.com /mesothelioma-biphasic.htm   (380 words)

  
 PA-04-035: CIRCULATING CELLS IN CANCER DETECTION
Enrichment will allow exfoliated cells and subcellular molecules, for example from urine, to be used for genomic, proteomic, and epigenomic analyses that may lead to improvements in the detection of bladder cancer through measurements of alterations in expressed genes, peptide profiles, and epigenetic markers.
With the advent of PCR-based detection of DNA from rare neoplastic cells in body fluids, mutations have been detected in ras genes from the stools of patients with colorectal cancer, in p53 from the urine of patients with bladder cancer, and in p53 genes in the sputum of patients with lung cancer.
However, the detection of abnormal exfoliated cells, for instance, cancer cells by routine cytopathological examination may be limited because the number of abnormal cells may be very small compared to the number of normal cells, is difficult.
grants1.nih.gov /grants/guide/pa-files/PA-04-035.html   (3898 words)

  
 Defining Signatures of Cancer Cells   (Site not responding. Last check: )
All cell types, depending on their functions, have unique, identifiable signatures or special characteristics such as which genes are active and what proteins or other cellular products are manufactured by the cell.
Cancers of the urinary tract may be signaled by cancer cells that are "shed" in the urine.
Generate a complete catalog of the distinguishing molecular signatures of normal, pre-cancerous, and cancerous cells; at all stages; in all tissues, and use the catalog to develop diagnostic techniques for the earliest detection of pre-cancerous lesions and cancers, develop signature-based therapies, and identify subsets of patients with different prognoses to predict therapeutic response.
plan2002.cancer.gov /scpsigs.htm   (2508 words)

  
 Epithelioid Mesothelioma Cancer - Mesothelioma Cancer Cells
Epithelioid mesothelioma is the most common form of mesothelioma and accounts for 50 to 70% of the mesothelioma cancer cells.
For example, epithelial cells are found in the skin, which separates the outside of the body from the inside of the body.
Carcinoma, however, is a type of cancer that originates in the epithelium and adenocarcinoma is a special type of carcinoma that originates in the lining or inner epithelium of an organ.
www.allaboutmalignantmesothelioma.com /mesothelioma-epithelioid.htm   (431 words)

  
 What Is Cancer?
Cancer is actually a group of many related diseases that all have to do with cells.
Cells are the very small units that make up all living things, including the human body.
Sometimes cancer cells break away from the original tumor and travel to other areas of the body, where they keep growing and can go on to form new tumors.
kidshealth.org /kid/health_problems/cancer/cancer.html   (1260 words)

  
 Sarcomatoid Mesothelioma Cancer - Mesothelioma Cancer Cells
These cells are typically oval shaped, but more irregular, and with the nucleus not as clearly visible under an electron microscope as the nuclei of the epithelioid mesothelioma cancer cells.
Although sarcomatoid cancer appears in other parts of the body, such as the kidney, sarcomatoid cancer is relatively rare in the lungs.
In these cases, the pathologist must be careful to compare the appearance and staining of the cells, along with the overall appearance (localized versus diffuse pleural-based mass) and regularity of the tumor when making a definitive diagnosis of malignant mesothelioma.
www.allaboutmalignantmesothelioma.com /mesothelioma-sarcomatoid.htm   (393 words)

  
 Defining the Signatures of Cancer Cells: Detection and Diagnosis, Scientific Priorities for Cancer Research, Plans and ...   (Site not responding. Last check: )
We have learned that during the transformation of a normal cell to a cancer cell, the signature changes, and that change becomes a signal of the presence of cancer.
For example, tobacco-induced molecular changes in the mouth may predict the risk of developing lung cancer, and cancers of the urinary tract may be signaled by cancer cells that are "shed" in the urine.
By assessing the meaning of individual changes in the cell's signature, we will be able to determine which cancers are most likely to progress and which are less likely to do so – a dilemma that confronts, for example, doctors treating patients with prostate cancer – thereby avoiding the consequences of unnecessary treatment.
2001.cancer.gov /defining.htm   (2341 words)

  
 Oncology Zone - Cancer News - Mesothelioma cancer - Lung Cancer - Breast Cancer - Prostate Cancer - Skin Cancer - ...
Read the latest headlines about cancer and Oncology news from around the globe, from the latest statistical studies to cutting edge treatments and procedures for a wide range of cancer topics.
By sharing information about the latest cancer news, articles, or even research studies with Oncology Zone, you are helping to create an invaluable resource in the fight against a horrible disease.
A variety of drugs are used to treat breast cancer in stages III and IV.
www.oncologyzone.com   (613 words)

  
 CNN.com - Study: Microbeams have big impact on cancer cells - Dec. 2, 2003
Scientists at Britain's Cancer Research UK charity have dubbed it the "bystander effect" because the cancer cells zapped by the microbeams not only die but send out suicide signals to other abnormal cells, telling them to self destruct.
Prise and his colleagues, who reported their findings in the journal Cancer Research, tested microbeams in the laboratory on brain cancer cells that were highly resistant to conventional radiotherapy.
An estimated 50 percent of patients diagnosed with cancer would benefit from radiotherapy, which kills cancerous cells with tight beams or radiation aimed at specific areas of the body.
www.cnn.com /2003/HEALTH/conditions/12/02/cancer.microbeams.reut   (544 words)

  
 STEM CELLS' REPAIR SKILLS MIGHT BE LINK TO CANCER
Johns Hopkins researchers say there is growing evidence that stem cells gone awry in their efforts to repair tissue damage could help explain why long-term irritation, such as from alcohol or heartburn, can create a breeding ground for certain cancers.
Over the last 10 years, researchers have found examples of these so-called cancer stem cells -- the cells within a tumor that are capable of regrowing the tumor -- in certain malignancies of the blood, breast and brain.
"Cancers associated with chronic irritation may be a good setting in which to determine whether stem cells are the starting place of tumors," says Phil Beachy, Ph.D., professor of molecular biology and genetics in Hopkins' Institute for Basic Biomedical Sciences and a Howard Hughes Medical Institute investigator.
www.hopkinsmedicine.org /Press_releases/2004/11_22_04.html   (658 words)

  
 Wired News: Cancer Stem Cells Hint at Cure   (Site not responding. Last check: )
Finding cancers' stem cells is a rapidly growing area of research, Weissman said, and it will be a main focus of the Institute of Cancer and Stem Cell Biology, which he heads at Stanford.
Cancer stem cells make up only a tiny number of the total cancer cells in a leukemia patient, which makes the cells next to impossible to find.
Scientists at the Reproductive Genetics Institute, a private clinic in Chicago, are also studying stem cells to discover the origins of disease.
www.wired.com /news/medtech/0,1286,64549,00.html   (744 words)

  
 Cforyourself: Cancer & Vitamin C
Ewan Cameron theorized that cancer cells excrete a substance, hyaluronidase, that breaks down the collagen and fibers that make up the structure of this ground substance which creates the space needed for tumor growth.
Cancer patients are advised to get intravenous injections of C if possible, especially if they are having trouble eating.
Due to its importance to the development of immune system cells, it is crucial as a first line of defense against mutated cells from ever multiplying into overt cancer.
www.cforyourself.com /Conditions/Cancer/cancer.html   (1994 words)

  
 Science NetLinks: Cancer Risks
As a result, students might perceive cancer as a group of foreign cells that are "invading" their normal cells, instead of knowing that cancer cells are simply normal body cells that have mutated.
Students might also be unaware of the fact that all cells in every human being have the potential to become cancerous.
Thus, students might think that cancer is a disease that you "catch" from others and the environment.
www.sciencenetlinks.com /lessons.cfm?BenchmarkID=5&DocID=86   (1074 words)

  
 Cancer Loves Sugar   (Site not responding. Last check: )
It is the replacement of normal oxygen respiration of the body's cells by an anaerobic [i.e., oxygen-deficient] cell respiration.
The cancer is constantly on the verge starvation and thus constantly asking the body to feed it.
Cancers loves cooked foods (this is a relatively recent finding) and cancer loves sugar.
www.mnwelldir.org /docs/nutrition/sugar.htm   (573 words)

  
 Scientists discover more about how cancer cells form and grow   (Site not responding. Last check: )
In the July issue of Cancer Cell, the scientists explain how cancer tumor cells attach themselves to a protein on the surface of cells lining blood vessel walls.
Wang speculated that if jagged1 is not secreted but found on the surface of tumor cells, then perhaps HGF gets jagged1 levels to increase, and that prompts a connection between the tumor and endothelial cells.
Wang said he found it interesting that although much research has looked at cancer cells' secretion of proteins to form blood vessels, notch's function in cancer angiogenesis has not gotten the same attention.
www.cancer.med.umich.edu /news/cancercells05.htm   (689 words)

  
 Cancer Issues - Laser Treatment Kills Cancer Cells in Lab
When nanotubes were placed inside cells and radiated by the laser beam, the cells were quickly destroyed by the heat.
However, cells that did not contain any nanotubes were not affected by the laser beam.
Standard chemotherapy destroys cancer cells and normal cells alike.
www.cancerissues.com /ms/news/527192/main.html   (425 words)

  
 Broccoli Packs Powerful Punch To Bladder Cancer Cells
University Of Pittsburgh Studies Broccoli-derived Chemicals To Prevent Prostate Cancer (December 26, 2003) -- Fruits and vegetables are good for overall health, and a newly funded study at the University of Pittsburgh Cancer Institute (UPCI) may show that certain vegetables, such as broccoli, also offer...
And the most profound effect was on the most aggressive form of bladder cancer they studied.
He and his colleagues treated two human bladder cancer cell lines and one mouse cell line with varying amounts of glucosinolates and isothiocyanates.
www.sciencedaily.com /releases/2005/07/050729063801.htm   (841 words)

  
 BBC NEWS | Health | HIV 'could destroy cancer cells'
His team is planning to see whether the virus could carry a therapeutic gene to the precise location of the cancer.
As well as controlling cancer, they hope this technique might be useful for treating genetic diseases.
Dr Georges Vassaux, from Cancer Research UK's clinical centre at Barts and The London, said: "This is the first time that a vector - or delivery system - for gene therapy has targeted a tumour in such a specific manner.
news.bbc.co.uk /1/hi/health/4257783.stm   (465 words)

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