
	Where results make sense

Topic: Carboxy group

Related Topics

Carboxylic acid

Carboxyl group

Lactic acid

Citric acid

Carbonyl

Reactivity series

Sulfuric acid

Nitrile

Functional group

Hydroxyl group

Saturation (chemistry)

Baking powder

Sodium carbonate

Naphthalene

Benzene ring

In the News (Wed 25 Nov 09)

Northern Trust

Marvin Harrison

Peter Chernin

Gary Locke

Match Play

Penelope Cruz

Mickey Rourke

AR Rahman

Danny Boyle

Hugh Jackman

	Patent 6,514,500
		To form covalent bonds with the functional group on a protein, one may use as a chemically reactive group (reactive entity) a wide variety of active carboxyl groups, particularly esters, where the hydroxyl moiety is physiologically acceptable at the levels required to modify the insulinotropic peptides.
		To form such bonds, one may use as a chemically reactive group coupled to the ITP a wide variety of active carboxyl groups, particularly esters, where the hydroxyl moiety is physiologically acceptable at the levels required.
		Such carboxy protecting groups are well known to those skilled in the art, having been extensively used in the protection of carboxyl groups in the penicillin and cephalosporin fields as described in U.S. Pat.
	pharmcast.com /Patents/Yr2003/Feb2003/020403/6514500_Glucagon020403.htm (8367 words)

	Ink jet printing inks - Patent 5383960
		B is a labile atom or group, hydroxy, amino or an ether, thioether or amine group; and
		As examples of phenyl radicals having 1 or 2 sulpho or carboxy groups there may be mentioned phenyl; 2-, 3- or 4-sulphophenyl; 2,4-, 2,5- or 3,5-disulphophenyl; 2-methyl-4-sulphophenyl; 2-methyl-5-sulphophenyl; 4-methyl-2-sulphophenyl; 2-sulpho-5-methylphenyl; 2-methoxy-5-sulphophenyl; 4-methoxy-2-sulphophenyl; 2-chloro-4-sulphophenyl; 2-chloro-5-sulphophenyl; 2,5-dichloro-4-sulphophenyl; 4-nitro-5-sulphophenyl; 5-nitro-2-sulphophenyl; 2-carboxy-5-sulphophenyl; and 3,5and 3,4-dicarboxyphenyl.
		As Examples of particularly preferred naphthyl radicals having 1, 2 or 3 sulpho or carboxy groups there may be mentioned 4-, 5-, 6- or 7-sulphonaphth-l-yl; 1- or 6-sulphonaphth-2-yl; 3,8- or 4,8-disulphonaphth-l-yl; 4,8- or 5,7-disulphonaphth-2-yl; 2,5,7- or 3,5,7-trisulphonaphth-2-yl; 1,5,7 or 3,6,8-trisulphonaphth-2-yl; 6-carboxy-8-sulphonaphth-2-yl and 6-carboxynaphth-2-yl.
	www.freepatentsonline.com /5383960.html (3977 words)

	Carboxylic acid
		In chemistry, especially in organic chemistry and biochemistry, a carboxylic acid or carboxy group is a functional group of the form
		Carboxylic acids react with bases to form carboxylate salts, in which the hydrogen of the -OH group is replaced with a metal ion.
		Carboxyl groups also react with amine groups to form peptide bonds, and with alcohols to form esters.
	www.wordlookup.net /ca/carboxylic-acid.html (483 words)

	R-5.7.1 Carboxylic acids
		group from each carboxy group of a carboxylic acid denoted by an "-oic acid" suffix or having a trivial name (see Table 28) is derived from the name of the corresponding acid by changing the ending "-oic acid" or "-ic acid" to "-oyl" or "-yl", respectively.
		When another group is present that has priority for citation as a suffix (see Table 10, R-4.1 and Table 5, R-3.2.1.1), a peroxy carboxylic acid group is indicated by the prefix "hydroperoxycarbonyl-".
		group is formed by modifying the "-oic" or "-carboxylic" suffix of a systematic name of an acid, or the "-ic acid" ending of the trivial name of an acid to "-imidic" or "-carboximidic acid", "-ohydrazonic" or "-carbohydrazonic acid", "-ohydroximic" or "-carbohydroximic acid", respectively (see Table 13 and R-3.4).
	www.acdlabs.com /iupac/nomenclature/93/r93_480.htm (956 words)

	Multi-atom probes (Site not responding. Last check: 2007-11-05)
		The aromatic ring AR is coplanar with the carboxy group, and might represent the benzene ring of benzoic acid or the heterocyclic ring of nicotinic acid.
		This ensures that the carboxy group will not be squeezed into a Target site that is too small for a larger molecule, but any dispersive or electrostatic attraction between the AR group and the Target site is not modelled.
		The aromatic ring AR is coplanar with the amide group, and might represent the benzene ring of benzamide or the heterocyclic ring of nicotinamide.
	www.moldiscovery.com /docs/grid/c70.html (1741 words)

	R-6.3 3-(2,3-DIHYDROXYPROPYL)-a-METHYLQUINOLINE-2-PENTANOIC ACID
		Note that the carbon atom of the carboxy group is included in the parent chain and that the numbering of the chain, although shown, is not that used to indicate substituents of the chain in the name of the complete compound.
		No locant is given to denote the position of the acyclic component attached to the heterocycle, because, by definition, the acyclic component must be attached at the atom furthest from the principal group (see R-1.2.4.1).
		(1) The prefix 'hydroxy-', the multiplicative prefix 'di-' and the locants '2' and '3', denote the presence of two hydroxy groups at positions 2 and 3 of a three-carbon chain (prop), derived from the parent hydride propane, with its free valence at position 1, as shown in (IV).
	www.acdlabs.com /iupac/nomenclature/93/r93_612.htm (371 words)

	LG-4
		When a methyl group of a lignan or neolignan is converted into a carboxy group this is indicated by the suffix -oic acid with the locant of this position.
		Esterification of an alcoholic or phenolic hydroxy group (see LG-4.5) is indicated by replacing the terminal -e of lignane, neolignane or oxyneolignane by -yl, (or by the prefix -diyl, -triyl, etc.) with the locant of the associated position and the anionic form of the acyloxy group.
		If there is a preferred group such as a carboxylic acid, lactone or ester of a carboxy group the esterified hydroxy group is indicated by an acyloxy prefix.
	www.chem.qmw.ac.uk /iupac/lignan/LG4.html (517 words)

	Structure of Proteins
		The stability of secondary structures is further dependent on the presence of compatible R groups among the amino acids.
		Figure 1.10, Lewin's Genes VI Phosphorylation is the addition of a phosphate group, typically to the R group of the amino acids serine, threonine and/or tyrosine.
		Glycosylation may be N-linked, attached to the nitrogen on the R group of asparagine, or O-linked, attached to the oxygen on the R group of serine or threonine (not shown).
	www.rhodes.edu /biology/glindquester/molbiol/mbprotected/proteins.html (2042 words)

	EC 2 Introduction
		Transferases are enzymes transferring a group, for example, the methyl group or a glycosyl group, from one compound (generally regarded as donor) to another compound (generally regarded as acceptor).
		These are mainly the enzymes transferring amino groups (sub-subclass EC 2.6.1) from a donor, generally an amino acid, to an acceptor, generally a 2-oxo acid.
		The most numerous section, that of phosphotransferases, is subdivided according to the acceptor group which may be an alcohol group (EC 2.7.1), a carboxy group (EC 2.7.2), a nitrogenous group such as that of creatine (EC 2.7.3), or a phosphate group as in the case of adenylate kinase (EC 2.7.4).
	www.chem.qmw.ac.uk /iubmb/enzyme/EC2/intro.html (513 words)

	97ps2key
		One, the acid form, would have both amino group and the carboxy group in the protonated state.
		The other would consist of a zwitterion, in which the carboxy group is deprotonated (-1) and the amino group protonated (+1).
		A protein is subjected to end group analysis by dansyl chloride.
	www.users.csbsju.edu /~hjakubow/classes/MiscStuff/97ps2key.html (1104 words)

	Acid-base aspects of amino acids (Site not responding. Last check: 2007-11-05)
		When writing the formula of a peptide, you should be able to "follow" the peptide chain, keep the peptide bonds on one line, and make sure that the side-chains are not in the way.
		With proline, however, there is no choice, as the imino group that is involved in the "peptide" bond is itself part of a ring.
		The amino terminal must be at the left, the carboxy terminal at the right.
	www.msu.edu /course/bmb/461/web/aminoacids.html (385 words)

	Proteins (Site not responding. Last check: 2007-11-05)
		Dissociation of the amino and carboxy groups occurs at physiological pH (i.e., approximately pH7).
		That is, one end has an -NH group and the other a -C00H group and therefore the amino acids are arranged R to R' in the -NH to -C00H direction.
		The entire grouping of polypeptides is considered to be a single protein.
	www.mansfield.ohio-state.edu /~sabedon/biol1035.htm (1342 words)

	Clarkson University School of Science, Potsdam, New York, U.S.A.
		Under strongly acidic pH conditions proteins are present as cations (+) as a result of suppression of the dissociation of the carboxy group and protonation of the amino group.
		At pH values above 12, they are present as anions (-) because the amino group is a free base and the carboxy group is dissociated.
		Due to the total net charge of proteins it is easily possible to bind them to a corresponding charged stationary phase as long as the salt concentration is kept low.
	people.clarkson.edu /~skeelsmc/chromatography.htm (459 words)

	Compounds which release cyan dyes or dye forming materials - Patent 4195993
		The compound must contain at least one CAR group and, except when R and R.sup.2 form a heterocyclic group and X is --SO.sub.2, the compound must contain at least one carboxy group.
		In addition to the ballast, the nucleus completed by Y may have groups or atoms attached thereto, such as halogen atoms, alkyl, aryl, alkoxy, aryloxy, nitro, amino, alkylamino, arylamino, amido, cyano, alkylmercapto, keto, carboalkoxy, and heterocyclic groups.
		R.sup.6 is hydrogen or an alkyl group of 1 to 6 carbon atoms;
	www.freepatentsonline.com /4195993.html (8789 words)

	How Quinolones Work...
		Quinolones bind to DNA gyrase via the carboxy group at C3 in the 4-quinolone ring so these are essential for activity.
		This carboxy group may also be responsible for chondrotoxicity as the same part of the molecule chelates cations like Mg2+.
		A methoxy group at C8 increases lethality particularly in Gram-positive bacteria.
	www.ims-global.com /insight/news_story/news_story_000106b.htm (136 words)

	Proteins are polypeptides
		The backbone of the protein chain is highly polar with the amino (-NH-) group a strong donor of hydrogen bonds and the carbonyl (-CO-) group an acceptor of hydrogen bonds.
		The atoms of the carboxy group of subunit 1 and the amino group of subunit 2 lie in a plane (called the peptide plane), and the only degrees of freedom along the backbone are about the
		The lipids are bilayered with hydrophilic groups facing the surface of the membranes and hydrophobic groups in the interior of the membranes.
	www.uic.edu /classes/phys/phys461/phys450/ANJUM05 (1901 words)

	the peptide bond (Site not responding. Last check: 2007-11-05)
		The peptide bond forms between the carboxy group of one amino acid and the amine group of another to form an amide
		Another property of double bonds is the lack of rotation, so the peptide group is fixed in either a cis or trans configuration.
		Even though the geometry of the peptide group is fixed, the bonds on either side of the alpha carbons can rotate, which allows flexibility in the peptide backbone.
	faculty.gvsu.edu /carlsont/mm/aa/dipeptide.html (181 words)

	[No title] (Site not responding. Last check: 2007-11-05)
		Fatty Acids - Long chain alkyl compounds with a carboxy group on one end, there is usually an even number of carbons, CH3(CH2)nCOOH where n = 1-22 2 Numbering Systems Systemic/ Chemical (individual u.f.a.): count from the carboxy group N:M;z where N is the number of carbons in f.a.
		head groups of glycerol phosphatides are not evenly distributed a.
		groups can move laterally, but very little flip-flop - requires energy 4.
	www.muhealth.org /~md2003/draft1/8-28_Lipid_Mos.doc (746 words)

	[No title]
		An amino acid consists of the following: one central carbon atom (Calpha) attached to a hydrogen atom (H), a carboxy group (COOH), an amino group (NH2), and a structure known as a side chain, which is unique to a given type of amino acid.
		The amino acids that constitute a protein are joined in a chain, called the backbone, by peptide bonds (alternately, the component amino acids are called residues).
		Peptide bonding occurs when the C atom of the carboxy group of acid Ak bonds to the N atom of the amino group in acid Ak+1.
	www.scs.carleton.ca /~oommen/papers/DrugDesign0.doc (1367 words)

	[No title] (Site not responding. Last check: 2007-11-05)
		This assignment of protection to the carboxy terminus defines the direction of the synthetic cycle as elongation from the carboxy terminus to the amino terminus, which is contrary to the method used by natural systems.
		By elaborating the growing peptide chain from the carboxy terminus, exposure of activated carbonyls to the peptide chain is limited and occurs only in the presence of
		The cost of automated systems remains a minor deterrent to their application, however, given the straightforward nature of synthesis on the solid phase and the numerous applications of it, the design and construction of an automated synthesizer from components should be possible.
	www.chem.uky.edu /research/cammers/pepsyn/spps.html (4490 words)

	The MSDS HyperGlossary: Carboxylic Acid
		The carbon atom of the carboxy group must also be attached to an organic group or a hydrogen.
		Carboxylic acids that have long (12 to 24 carbon atom) unbranched aliphatic groups are called fatty acids.
		When a carboxylic acid is neutralized with a base it becomes a salt that is itself a weak base.
	www.ilpi.com /msds/ref/carboxylicacid.html (482 words)

	Synthetic studies towards the development of a novel class of acitretin-type retinoids (Site not responding. Last check: 2007-11-05)
		These analogs are characterized by a highly electron-rich benzene ring in the lipophilic part and two amide bonds, replacing the C7-C8 and C11-C12 double bonds, with simultaneous restriction of the C9-C10 double bond, in the spacer compared to acitretin.
		This group is readily introduced into the carboxy function, monoprotected derivatives are readily separated by flash column chromatography (FCC) from the undesired byproducts from diesterification and finally it is efficiently removed under mild reaction conditions with sodium thiophenolate.
		We thought that the monodiphenylmethyl ester 21 would be a good candidate because the benzhydryl protecting group is readily removed from a carboxy function under mild acidic conditions.
	www.arkat-usa.org /ark/journal/2003/I06_Varvoglis/AV-671A/671A.asp (4681 words)

	Assay for the transbilayer distribution of glycolipids: selective oxidation of glucosylceramide to glucuronylceramide ...
		ring hydroxyl groups that are cis to one another.
		groups even in the presence of secondary alcohol groups (20)
		The glucuronylceramide migrated slower in the acid than in the alkaline solvent (even as a protonated species), which may be due to an overriding effect of the increased polarity of the carboxyl group because the acidic solvent is less polar.
	www.jlr.org /cgi/content/full/41/8/1252 (4735 words)

	The 20 Amino Acids
		) and a "carboxy" group (COOH) (shown in fl in the diagram).
		are acidic ("carboxy" group in the side chain).
		are basic ("amine" group in the side chain).
	www.people.virginia.edu /~rjh9u/aminacid.html (69 words)

	(WO 03/106482) PEPTIDES DERIVATIVES COMPRISING THIAZEPINE GROUP FOR THE TREATMENT OF HYPERLIPIDEMIC CONDITIONS (Site not responding. Last check: 2007-11-05)
		PEPTIDES DERIVATIVES COMPRISING THIAZEPINE GROUP FOR THE TREATMENT OF HYPERLIPIDEMIC CONDITIONS
		(57) The present invention relates to compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia.
		Processes for their manufacture and pharmaceutical compositions containing them are also described.
	wipo.int /ipdl/IPDL-CIMAGES/view/pct/getbykey5?KEY=03/106482.031224&... (223 words)

	CBX (From: 1TYS.PDB; Formula: C1 H1 O2; resolution. 1.8 A.; Name(s): carboxy group; carboxylic group)
		COMPND CBX CARBOXY GROUP; CARBOXYLIC GROUP REMARK CBX Extracted from PDB file 1tys.pdb REMARK CBX Formula C1 H1 O2 REMARK CBX Nr of non-hydrogen atoms 3 REMARK CBX Residue type CBX REMARK CBX Residue name 257 REMARK CBX Original residue name (for O) $0 REMARK CBX RESOLUTION.
		assuming O -> 15.99900 + 1.008 * 0 (Hs) autogenerate angles=true end RESIdue CBX GROUp ATOM C TYPE CX1 CHARge 0.0 END !
		Nr of Hs = 1 ATOM O1 TYPE OX2 CHARge 0.0 END !
	xplor.csb.yale.edu /xplor-info/hetero/CBX.html (492 words)

Try your search on: Qwika (all wikis)