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Topic: Cardiomyopathy diabetes deafness

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Cardiomyopathy diabetes deafness

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	A3243G - Abstracts - Search Results for .
		HLA-DQ polymorphism and degree of heteroplasmy of the A3243G mitochondrial DNA mutation in maternally inherited diabetes and deafness.
		[A new subtype of diabetes mellitus: maternally inherited diabetes and deafness (MIDD)]
		Maternally inherited diabetes and deafness: prevalence in a hospital diabetic population.
	www.a3243g.com /abstract_pm_db_list_search_results.asp (3061 words)

	Symptoms
		Scoliosis and ECG evidence of cardiomyopathy were found in over two-thirds of the patients studied; pes cavus, distal amyotrophy, optic atrophy, nystagmus and deafness were all less frequent.
		Diabetes appeared to be associated with a higher incidence of optic atrophy and deafness.
		Similarly, cardiomyopathy ran true within affected members of the same sibship, but there were instances of discordance which suggest that the development of the non-neurological features of Friedreich's ataxia may be controlled by modifying genes rather than heterogeneity of the main gene.
	www.fortnet.org /fapg/symptoms.htm (321 words)

	Cardiomyopathy diabetes deafness (Site not responding. Last check: 2007-10-30)
		The combination of diabetes mellitus, neurosensory hearing loss, and hypertrophic cardiomyopathy is a rare disease, occurring in less than 1 in 2000 in general population.
		It was evaluated at about 2% in patients with neurosensory hearing loss, at 10% in those with both neurosensory hearing loss and diabetes mellitus, and at 13% if there is a family history of possible maternal inheritance of hearing loss or diabetes mellitus.
		The age of onset of diabetes mellitus, neurosensory hearing loss, and cardiomyopathy in these patients is between their teens and forties.
	www.orpha.net /static/GB/cardiomyopathy_diabetes_deafness.html (163 words)

	Health Topics
		Alström syndrome is an inherited disease characterized by progressive blindness, deafness, early-onset type 2 diabetes mellitus, and obesity.
		Diabetes can be treated with oral medications, insulin, or a combination of both.
		Diabetes and high cholesterol increase the risk of coronary artery disease.
	www.netwellness.org /ency/article/001665.htm (454 words)

	United Mitochondrial Disease Foundation - Medical Article List by Subject
		Bakker ; HD ; 1033 ; Neonatal cardiomyopathy and lactic acidosis responsive to thiamine.
		Grunnet ; M.L. ; Juvenile Leigh's encephalomyelopathy with peripheral neuropathy, myopathy, and cardiomyopathy.
		Kitaoka ; H ; 3635 ; A patient with diabetes mellitus, cardiomyopathy, and a mitochondrial gene mutation: confirmation of a gene mutation in cardiac muscle.
	biochemgen.ucsd.edu /umdf/mito-cardio.htm (3261 words)

	periodontal disease, diabetes and the aging process vs coenzyme Q10
		's therapeutic strength in treating cardiomyopathy, a mixed bag of conditions impairing the heart muscle that collectively are the third most common form of cardiovascular disease.
		Cardiomyopathy often is the most life threatening of all heart conditions, and it's probably the number one reason that people undergo a heart transplant operation.
		have helped a clear majority of my cardiomyopathy patients, and several of them, who were on the waiting list for a donor heart, found that their old heart would do just fine.
	www.home.earthlink.net /~recruiting/AtkinsQ10.html (2029 words)

	Diabetes Directory: Diabetes Hearing Loss (Site not responding. Last check: 2007-10-30)
		Diabetes testing, diet for diabetes, male health problems caused by type 2 d...
		diabetes recipes diabetes supply what is diabetes american diabetes diabetes information diabetes hearing loss diabetes news pregnancy diabetes diabetes insipidus adult diabetes dog diabetes cinnamon...
		Diabetes alcohol - diabetes food pyramid, symptom of sugar diabetes, diabete...
	www.diabetesdir.com /Diabetes10/diabeteshearingloss (1354 words)

	Brain Foundation - Friedreich's Ataxia
		Research into the biochemistry, neurobiology, and biophysics of central and peripheral nerves, heart and skeletal muscle, and the interactions between muscle and nerve to uncover the pathological process of Friedreich's ataxia is being carried out.
		In addition, studies of diabetes and heart disease are being conducted in order to determine their relationship with this neurological disorder.
		Generally, within 15 to 20 years after the appearance of the first symptoms, the person is confined to a wheelchair, and in later stages of the disease, individuals become completely incapacitated.
	www.brainaustralia.org.au /AZ_of_Brain_Disorders/friedreichs_ataxia?&mysource_site_extension=printer_friendly_pages (588 words)

	Heart failure patients treated for diabetes with insulin have increase in mortality
		UCLA researchers for the first time showed that advanced heart failure patients with diabetes who are treated with insulin faced a mortality rate four times higher than heart failure patients with diabetes treated with oral medications.
		Researchers assessed the history of diabetes and insulin treatment in 554 patients with advanced heart failure after adjusting for various risk factors.
		One year survival rates were 89.7 percent for non-diabetic patients, 85.8 percent for non-insulin-treated diabetic patients, and only 62.1 percent for insulin-treated diabetic patients.
	www.medicalnewstoday.com /medicalnews.php?newsid=18528 (372 words)

	Mitochondrial References (M-Z), "The Biglist" (Site not responding. Last check: 2007-10-30)
		Maassen, J. A., Biberoglu, S., t Hart, L. M., Bakker, E. and de Knijff, P. "A case of a de novo A3243G mutation in mitochondrial DNA in a patient with diabetes and deafness." Archives of Physiology and Biochemistry 110(3):186-188.
		Maassen, J. A., van den Ouweland, J. M., tHart, L. and Lemkes, H. "Maternally inherited diabetes and deafness: a diabetic subtype associated with a mutation in mitochondrial DNA." Hormone and Metabolic Research 29(2):50-55.
		Mathews, C. and Berdanier, C. "Noninsulin-dependent diabetes mellitus as a mitochondrial genomic disease." Proceedings of the Society for Experimental Biology and Medicine 219(2):97-108.
	mitomap.bio.uci.edu /mitomap/biglist_M_Z.html (12049 words)

	Dog - Wikipedia, the free encyclopedia
		Some breeds of dogs are also prone to certain genetic ailments, such as hip dysplasia, luxating patellas, cleft palate, blindness, or deafness.
		Dogs are also susceptible to the same ailments that humans are, including diabetes, epilepsy, cancer, and arthritis.
		Gastric torsion and bloat is a dangerous problem in some large-chested breeds.
	en.wikipedia.org /wiki/Dog (5681 words)

	Mitochondrial DNA in Aging and Disease
		Sometimes inherited mitochondrial DNA defects yield premature versions of disorders that afflict many people in their later years, such as diabetes, deafness, heart disease, muscle weakness, movement problems and dementia.
		A particularly intriguing possibility is that a significant fraction of type II (maturity-onset) diabetes mellitus, which afflicts millions of Americans older than 40 years, may be rooted in inherited mitochondria DNA defects still to be discovered.
		Diabetes is known to run in families, and the mother is often the affected parent (as would be expected with mitochondrial DNA inheritance).
	www.genethik.de /mitochondrial.htm (3912 words)

	Coenzyme Q10
		There is conflicting evidence from research on the use of CoQ10 in patients with dilated or hypertrophic cardiomyopathy.
		Heart damage (cardiomyopathy) is a major concern with the use of anthracyclines, and CoQ10 has been suggested to protect the heart.
		Caution is advised in patients with diabetes or hypoglycemia, and in those taking drugs, herbs, or supplements that affect blood sugar.
	www.allnutritionals.com /natural-products/coenzyme-q10.shtml (3467 words)

	Geometry.Net - Health_Conditions: Alstrom Syndrome
		Another of the first signs MAY be dilated cardiomyopathy and congestive heart failure in infants under 1 year of age.
		The features of this very complex disorder are childhood blindness, early hearing loss, diabetes, kidney failure and cardiomyopathy, a heart condition which if left untreated can lead to heart failure.
		Cardiomyopathy may be the first symptom to present with AlstrÃ¶m Syndrome, in many of the children with AlstrÃ¶m Syndrome cardiomyopathy has presented during the first 6 months of life.
	www.geometry.net /detail/health_conditions/alstrom_syndrome.html (1333 words)

	eMedicine - MELAS Syndrome : Article by Fernando Scaglia, MD (Site not responding. Last check: 2007-10-30)
		Usually, type II diabetes is described in individuals with MELAS, although type I or insulin-dependent diabetes also may be observed.
		Patients may experience shortness of breath secondary to cardiomyopathy, which usually is of the hypertrophic type; however, dilated cardiomyopathy also has been described.
		Cardiomyopathy with signs of congestive heart failure (CHF) also may be observed in the physical examination.
	www.emedicine.com /PED/topic1406.htm (4627 words)

	Aging research; molecular concepts of aging, related diseases and cloning.
		This (40) mutation is associated with maternally inherited sensory neural hearing loss, and confers increase sensitivity to aminoglycoside antibiotic-induced deafness (31, 32).
		This mutation resulted in sensory neural deafness and seizures in childhood with progressive encephalomyopathy leading to retinitis pigmentosa, glaucoma, seizures, and severe cerebral calcification (Fahr's disease) by age 27.
		MtDNA rearrangement mutations have been associated with maternally inherited diabetes and deafness, the ocular myopathies including chronic progressive external ophthalmoplegia (CPEO) and the Kearns-Sayre Syndrome (KSS), and with the Pearson's marrow pancreas syndrome.
	www.innovitaresearch.org /survey/Chapter_2_03.html (1186 words)

	DHEA, antibiotics, Weight Loss drugs, weight loss herbs, weight loss herbal formula, hair loss, hair growth, buy Rx ... (Site not responding. Last check: 2007-10-30)
		It is concluded that the protection is due to a low expression of mitochondrial proteins, as well as to a lack in cardiolipin as constituent of the lipid bilayer of the inner mitochondrial membrane.
		We describe a case of diabetes mellitus complicated by neurosensory hearing loss, cardiomyopathy, and sleep apnea syndrome.
		A 48-year-old man who was admitted for treatment of a lacerated tendon of the right shoulder was also found to require preoperative control of diabetes, a condition that had been diagnosed 4 years earlier.
	www.twinpharm.com /ref-mitochondria-1/mitochondria-1-research-abs4.779.html (1158 words)

	DHEA, antibiotics, Weight Loss drugs, weight loss herbs, weight loss herbal formula, hair loss, hair growth, buy Rx ... (Site not responding. Last check: 2007-10-30)
		We report the case of fifty-two year-old mentally deficient female who presented with diabetes mellitus, deafness, stroke-like episodes, cardiomyopathy, and macular pattern dystrophy of the retina.
		The question of whether a diabetic microangiopathy may be responsible stroke-like episodes is discussed.
		We suggest it was rather a complicated form of diabetes-deafness than a incomplete MELAS syndrome associated with mitochondrial diabetes.
	www.twinpharm.com /ref-mitochondria-1/mitochondria-1-research-abs4.624.html (1241 words)

	eMedicine - Friedreich Ataxia : Article by Natalya V Bulaeva, MD, PhD (Site not responding. Last check: 2007-10-30)
		Diabetes mellitus occurs in 10% of patients with FA, and an additional 10-20% have impaired glucose tolerance.
		Echocardiogram exhibits evidence of hypertrophic cardiomyopathy in approximately 40% of patients.
		Death often is related to cardiomyopathy and diabetes, but aspiration pneumonia due to dysphagia also may shorten the lifespan of patients with FA.
	www.emedicine.com /orthoped/topic109.htm (2037 words)

	Mucopolysaccharidosis type vi: risk factors, symptoms, diagnosis and treatment. (Site not responding. Last check: 2007-10-30)
		diabetes, ketoacidosis, nephropathy, neuropathy, retinopathy, gestational diabetes, hypoglycemia, type 1, type 2
		Acute infantile cardiomyopathy also has been reported in MPS VI.
		Perform an audiological evaluation because deafness and hearing loss commonly occur in MPS.
	www.overcome-diabetes.com /maroteaux-lamy.htm (640 words)

	The Spectrum of Systemic Involvement in Adults Presenting with Renal Lesion and Mitochondrial tRNA(Leu) Gene Mutation ...
		(3 of 9), neuromuscular involvement (2 of 9), hypertrophic cardiomyopathy
		Type 2 diabetes was diagnosed at age 32.
		Diabetes mellitus was diagnosed in 12 of the 15 adult patients
	www.jasn.org /cgi/content/full/14/8/2099?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=mitochondrial+&andorexactfulltext=and&searchid=1109459205214_1740&stored_search=&FIRSTINDEX=0&sortspec=relevance&firstpage=2099&resourcetype=1&journalcode=jnephrol (4177 words)

	A3243G - Abstract - A novel mutation in the mitochondrial 16S rRNA gene in a patient with MELAS syndrome, diabetes ...
		A3243G - Abstract - A novel mutation in the mitochondrial 16S rRNA gene in a patient with MELAS syndrome, diabetes mellitus, hyperthyroidism and cardiomyopathy.
		Using RNase protection analysis, we found a novel C to G mutation at nucleotide position 3093 of mitochondrial DNA (mtDNA) in a previously reported 35-year-old woman exhibiting clinical features of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome together with diabetes mellitus, hyperthyroidism and cardiomyopathy.
		The complex I activity in the proband's fibroblasts was decreased to 47% of the control but those of the fibroblasts of the mother and three sons of the proband were not significantly changed.
	www.a3243g.com /abstract_pm_db_view.asp?ID=11455195 (419 words)

	MEDArticleMgr
		Permanent blindness and deafness is likely to develop.
		Call your health care provider if you suspect symptoms of diabetes mellitus such as increased thirst and urination.
		It is impossible to cover every eventuality in any answer, which makes direct contact with your health care provider imperative.
	www.drgreene.org /body.cfm?id=49&action=Display&articlenum=1665 (509 words)

	Medical Literature
		Cagianut B, Hochstrasser P, Rhyner K (1977): Diabetes juvenilis, tapeto-retinale degeneration, neurogene schwerhorigkeit (Alström -Syndrom), assoziiert mit einer kongenitalen dyserythropoietischen anomie typ III.
		Warren SE, Schnitt SJ, Bauman AJ, Gianelly RE, Landsberg L, Baim DS (1987): Late onset dilated cardiomyopathy in a unique familial syndrome of hypogonadism and metabolic abnormalities.
		Weinstein RL, Kliman B, Scully RE (1969): Familial syndrome of primary testicular insufficiency with normal virilization, blindness, deafness and metabolic abnormalities.
	www.jax.org /alstrom/documents/med_lit.html (2070 words)

	Diseases and Other Conditions Affecting Health of Cats
		Feline disease profile on feline diabetes, a disease that strikes many cats, but one that can be managed through diet and medication.
		Cats can compensate for early degrees of hearing loss, so sometimes their human companions are unaware of the problem until complete deafness occurs.
		Feline disease profile on Hypertrophic Cardiomyopathy, a disease of the heart which affects cats of all ages.
	cats.miningco.com /od/diseasesandconditions (886 words)

	Friedreich Ataxia (Site not responding. Last check: 2007-10-30)
		About two-thirds of individuals with FRDA have cardiomyopathy, 30% have diabetes mellitus, and about 25% have an "atypical" presentation with later onset, retained tendon reflexes, or unusually slow progression of disease.
		Death is often related to cardiomyopathy; aspiration pneumonia caused by dysphagia may also shorten the life span.
		1999) found a correlation between the incidence of diabetes mellitus and an earlier age of onset.
	www.geneclinics.org /profiles/friedreich/details.html (7690 words)

	Coenzyme Q10
		A review of the most recent studies involving CoQ10 and its health-protective effects reveals a promising role for this nutrient in breast cancer, diabetes mellitus, heart attacks, lowering ‘bad’ cholesterol, brain function, fertility, and as a supportive antioxidant that restores and regenerates other antioxidants.
		Recently, a small, but significant, study, by pioneer CoQ10 researchers at the Langsjoen Clinic in Tyler, Texas, showed that this coenzyme has a powerful influence in correcting an often fatal heart condition: hypertrophic cardiomyopathy, which involves an abnormal enlargement of the heart muscle, a condition accompanied by depressing fatigue and difficulty in breathing.
		In another human clinical trial, researcher William Lee, Ph.D., found that, on a daily dosage of 60 mg of CoQ10 for 3-12 weeks, patients with cardiovascular problems, cancer, and diabetes significantly raised their levels of immunoglobulin G, an antibody important for immune function.
	www.delano.com /ReferenceArticles/Coenzyme-Q10-Getting.html (903 words)

	Alstrom Syndrome - Patient UK
		Alstrom syndrome in childhood is difficult to recognize without the development of infantile cardiomyopathy and may not be identified until diabetes mellitus develops in the second or third decade.
		The diagnosis should be considered in all patients with infantile cone and rod retinal dystrophy, especially if the weight >90th centile or if there is infantile cardiomyopathy.
		Alstrom CH, Hallgren B, Nilsson LB Asander H; Retinal degeneration combined with obesity, diabetes mellitus and neurogenous deafness: a specific syndrome (not hitherto described) distinct from the Laurence-Moon-Biedl syndrome.
	www.patient.co.uk /showdoc/40002440 (266 words)

	Neuropathy Proximal
		A complete understanding of the complex relations between oxidative-nitrosative stress and PARP activation in diabetes may require cutting-edge technologies such as genomics and proteomics.
		The Diabetic Foot Update 2005: A Multidisciplinary Approach will be held at the Westin Riverwalk Hotel, located at 420 West Market Street in San Antonio, Texas.
		This nerve disorder should be suspected in all patients with type 2 diabetes and in patients who have had type 1 diabetes for more than five...
	neuropathyproximal.marsneuropathy.com (1234 words)

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