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| | Creative Technology Contributions & Links (Site not responding. Last check: 2007-11-06) |
 | | First, let’s begin with Carlos Bustamante, a Howard Hughes Medical Institute investigator, who in 1990, along with the help of his colleagues at the University of Oregon, tacked one end of a DNA molecule to a magnetic bead and measured its elasticity by tugging at the bead with magnets (Kher 2001)(See Figure below). |
 | | Also, Bustamante, whose goal is to someday build a living cell, using an atomic force microscope and a laser tweezer may have found a way to get past bucket biochemistry, which is characterized by studying molecular machines as population. |
 | | Another project I found interesting was performed by 1997 when Bustamante grasped a single protein and, applying forces only a trillionth as strong as those the earth exerts on an apple, pull it apart like a molecular Velcro (Kher 2001) This was done to study how proteins and nucleic acids fold into their complex structures. |
| www.colorado.edu /che/chen1000/bustamante.html (582 words) |
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