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Topic: Carlos Bustamante


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In the News (Mon 13 Oct 08)

  
  CATHOLIC ENCYCLOPEDIA: Carlos Maria Bustamante
In 1796 he took up the study of law, participated in the attempts to secure independence from Spain, and, when that was finally achieved, opposed the designs of Iturbide to transform the newborn republic into a hereditary monarchy.
Bustamante distinguished himself by publishing historical works on colonial times, till then in manuscript, and partly forgotten.
Bustamante's anti-Spanish feelings influence even his scientific publications and detract from their value.
www.newadvent.org /cathen/03088b.htm   (444 words)

  
 Encyclopedia: Carlos Bustamante
Bustamante is a member of the National Academy of Sciences.
Carlos Bustamante uses novel methods of single-molecule visualization, such as scanning force microscopy, to study the structure and function of nucleoprotein assemblies.
His laboratory is developing methods of single-molecule manipulation, such as optical tweezers, to characterize the elasticity of DNA, to induce the mechanical unfolding of individual protein molecules, and to investigate the machine_like behavior of molecular motors.
www.nationmaster.com /encyclopedia/Carlos-Bustamante   (304 words)

  
 Hartl Lab - People
Bustamante, C., R. Nielsen, and D. Hartl, 2002 Maximum likelihood and Bayesian methods for estimating the distribution of selective effects among classes of mutations using DNA polymorphism data.
Bustamante, C. Nielsen, and D. Hartl, 2002 A maximum likelihood method for analyzing pseudogene evolution: Implications for silent site evolution in humans and rodents.
Bustamante, C., J. Townsend and D. Hartl, 2000 Solvent accessibility and purifying selection within proteins of Escherichia coli and Salmonella enterica.
www.oeb.harvard.edu /hartl/lab/people/past/carlos.html   (388 words)

  
 Unique study reveals new details on how genes are transcribed
Carlos Bustamante, a biophysicist who holds a joint appointment with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California at Berkeley (UC Berkeley), heads the group that published the results of this work in the March 31 issue of the journal Science.
Bustamante and his colleagues speculate that within a cell there may be other molecules that bind to the RNAP to stabilize its conformation, so that it transcribes at a faster or slower rate-which in turn would make it more or less susceptible to pausing.
NOTE: Carlos Bustamante is a professor in UC Berkeley's Department of Molecular and Cell Biology, the Department of Physics, and the Department of Chemistry.
www.eurekalert.org /pub_releases/2000-04/LBNL-Usrn-0204100.php   (996 words)

  
 New Inventions
Bustamante and the paper's two lead authors, graduate students Zev Bryant and Michael Stone, are at the University of California, Berkeley.
Bustamante and his colleagues discovered from this analysis that the DNA molecule was about 40 percent more resistant to twisting than had been reported by other researchers.
For example, Bustamante and his colleagues are now using the same experimental apparatus to explore how the enzyme DNA polymerase — which copies a single DNA strand by pulling itself along the strand's length — exerts torque on the DNA strand as it works.
bathindadoctors.com /information/new_inventions/dna.html   (797 words)

  
 Faculty Profiles || Carlos Bustamante   (Site not responding. Last check: 2007-11-06)
The phi-29 portal motor discovered by Carlos Bustamante and his colleagues is a protein that packs viral DNA into a space 6,000 times smaller than normal volume.
In the case of phi-29, Bustamante's optical tweezers measured not only the work done by the protein motor, but also the pressure exerted by the packaged DNA on the interior of the bacteriophage, and the energy released when the DNA is injected into a host bacterium.
Bustamante is at the forefront of interdisciplinary research at UC Berkeley.
nano.berkeley.edu /nanosite/faculty/profiles/bustamante.html   (865 words)

  
 Creative Technology Contributions & Links   (Site not responding. Last check: 2007-11-06)
First, let’s begin with Carlos Bustamante, a Howard Hughes Medical Institute investigator, who in 1990, along with the help of his colleagues at the University of Oregon, tacked one end of a DNA molecule to a magnetic bead and measured its elasticity by tugging at the bead with magnets (Kher 2001)(See Figure below).
Also, Bustamante, whose goal is to someday build a living cell, using an atomic force microscope and a laser tweezer may have found a way to get past bucket biochemistry, which is characterized by studying molecular machines as population.
Another project I found interesting was performed by 1997 when Bustamante grasped a single protein and, applying forces only a trillionth as strong as those the earth exerts on an apple, pull it apart like a molecular Velcro (Kher 2001) This was done to study how proteins and nucleic acids fold into their complex structures.
www.colorado.edu /che/chen1000/bustamante.html   (582 words)

  
 2005 Winter Meeting - Featured Speakers
Bustamante, a Howard Hughes Medical Institute investigator at the University of California, Berkeley, came to the United States from Peru 26 years ago as a Fulbright scholar.
Bustamante’s research interests include the development of novel methods of single molecule manipulation and detection (such as Optical Tweezers and Single Molecule Fluorescence microscopy) and their application to study the behavior of DNA-binding molecular motors and the mechanical unfolding of globular proteins and RNA's.
Bustamante received his B.S. degree from Universidad Peruana Cayetano Heredia in Lima, Peru; his M.S. in biochemistry from Universidad Nacional Mayor de San Marcos; and his Ph.D. in biophysics from University of California, Berkeley.
www.aapt.org /Events/130th/speakers.cfm   (1614 words)

  
 Molecular motor packs DNA into viruses at greater than champagne pressures, researchers report
For nearly four years, Bustamante and his colleagues at the University of Minnesota tried pulling on the DNA as it is being stuffed into the capsid in an attempt to measure the force generated by the packing motor.
Among the other questions Bustamante and his colleagues hope to answer is whether the bacteriophage's portal motor is a rotating motor, like the motor that powers the tail or flagellum of some bacteria.
Bustamante is a member of UC Berkeley's Health Sciences Initiative, a broad effort bringing together researchers from many disciplines to work on health problems of the 21st century.
www.eurekalert.org /pub_releases/2001-10/uoc--mmp101801.php   (1049 words)

  
 National Academy of Sciences - Members   (Site not responding. Last check: 2007-11-06)
Bustamante has been a pioneer in the field of mechanochemistry, devising ingenious single-molecule methods to manipulate and investigate proteins, DNA, and RNA.
Using magnetic and laser tweezers, he and his group have been able to measure the tiny mechanical forces that allow macromolecules to drive living processes, increasing our understanding of how cells and organisms work.
I am now using single-molecule approaches to study the mechanical unfolding of proteins and RNA, to study the operation of nucleic-acid-binding molecular motors such as RNA and DNA polymerases, and to characterize the mechanical properties of proteins and nucleic acids to better understand their performance in the cell.
www4.nationalacademies.org /nas/naspub.nsf/(urllinks)/NAS-5B2PAL?opendocument   (276 words)

  
 CNN/TIME - America's Best
Bustamante, 50, a Howard Hughes Medical Institute investigator at the University of California, Berkeley, came to the U.S. from Peru 26 years ago as a Fulbright scholar.
In the early 1990s, while at the University of Oregon, he and his colleagues tacked one end of a DNA molecule to a magnetic bead and measured its elasticity by tugging at the bead with magnets.
Bustamante had refined his techniques sufficiently by 1997 to grasp a single protein and, applying forces only a trillionth as strong as those the earth exerts on an apple, pull it apart like molecular Velcro.
www.cnn.com /SPECIALS/2001/americasbest/science.medicine/pro.cbustamante.html   (549 words)

  
 Burroughs Wellcome Fund: Board of Directors
Bustamante received his B.S. degree from Cayetano Heredia University in Lima, Peru, his masters in biochemistry from San Marcos University, and his Ph.D. in biophysics from the University of California-Berkeley.
Dr. Bustamante is a Howard Hughes Medical Institute investigator and Professor of Molecular and Cell Biology, Physics, and Chemistry at the University of California-Berkeley.
Bustamante served on BWF’s Interfaces Advisory Committee from 2001 to 2003 and was elected to the National Academy of Sciences in 2002.
www.bwfund.org /about_us/board_of_directors.html   (1680 words)

  
 Councilmember Carlos Bustamante | The City of Santa Ana   (Site not responding. Last check: 2007-11-06)
Carlos Bustamante was born in Santa Ana to immigrant parents in 1965.
Carlos continued to seek other opportunities to learn, which lead to his present position with the County of Orange, County Executive Office.
Carlos was elected to the City Council in November 2004.
www.ci.santa-ana.ca.us /mayor/council/cbustamante   (261 words)

  
 Carlos Bustamante, Ph.D.
Using magnetic beads, an atomic force microscope, and laser tweezers, Carlos Bustamante has developed innovative ways to investigate the physical forces that drive the movement of individual molecules within cells.
Bustamante's enthusiasm for tinkering with machines in the laboratory has its roots in his childhood.
Bustamante first became interested in the physical forces at work in DNA replication in the late 1980s, while at the University of New Mexico.
www.hhmi.org /research/investigators/bustamante_bio.html   (821 words)

  
 2002-2003 Highlights: Biosciences and Health: Mighty Biomolecular Motors
The biomolecular motor that Bustamante and his colleagues observed is the portal motor for the bacteriophage ø29 (phi-29), a virus that infects and destroys soil bacteria, and is considered an excellent model system for studying viral assembly.
Biophysicist Carlos Bustamante with the optical tweezers setup used to measure the strength of bacteriophage ø29's portal motor.
Collaborating with Bustamante on this research were Doug Smith, now with UC San Diego, and Sander Tans, now at the Institute for Atomic and Molecular Physics in Amsterdam, along with UC Berkeley's Steven Smith, and Shelley Grimes and Dwight Anderson of the University of Minnesota.
www.lbl.gov /Science-Articles/Research-Review/Highlights/2002/stories/biosciences/mighty.html   (864 words)

  
 California Alumni Association at UC Berkeley   (Site not responding. Last check: 2007-11-06)
But what Bustamante has found is that RNA polymerase really acts in fits and starts, moving quickly sometimes, while at other times moving slowly or not at all.
Bustamante’s interest in the microscopic world took root in his father’s library, where he discovered a biography of the great neurologist Santiago Ramón y Cajal, a Spanish scientist who won the Nobel Prize in 1906 with Camillo Golgi.
Bustamante was again working with microscopes, albeit far more sophisticated ones than those of his youth--signal fluorescence microscopes, spectroscopic microscopes, and atomic force microscopes (which are capable of “feeling” the atomic structure of a surface).
www.alumni.berkeley.edu /Alumni/Cal_Monthly/November_2002/Force_of_nature.asp   (2010 words)

  
 SignOnSanDiego.com > News > Business -- Huge Matrix air facility in Tijuana will deal in cargo
Carlos Bustamante, its president, said Thursday that about $10 million will be spent initially to convert the massive structure into an air cargo facility that will begin operating later this year.
A joint venture for Bustamante, Dunning and the W.H. Chou textile and garment conglomerate, the operation was touted as the world's most sophisticated aircraft repair station.
Bustamante said the operation was impeded by a lack of skilled employees, parts held up at the border and the 1994 peso crisis.
www.signonsandiego.com /news/business/20030125-9999_1b25matrix.html   (636 words)

  
 University will confer honorary degrees on three scholars
Carlos Bustamante, who will receive a Doctor of Science honorary degree, is the Luis Alvarez professor of physics at the University of California, Berkeley.
Nominated by the Institute for Biophysical Dynamics, Bustamante is a pioneer in single molecule studies of nucleic acids and proteins.
Bustamante is a Howard Hughes Medical Institute Investigator and a member of the National Academy of Sciences.
chronicle.uchicago.edu /050609/honorarydegrees.shtml   (938 words)

  
 21 de septiembre de 1848. - Fallece don Carlos María de Bustamante, uno de los redactores del Acta del Congreso de ...
Bustamante de tal manera que consideró injusta la prisión que sufría el Lic.
Bustamante y otros diputados fueron arrestados bajo los cargos de iniciar una conspiración en contra de Iturbide?
Las denuncias que hace Bustamante a través de sus artículos le crean serias dificultades y persecuciones, entonces, para defenderse publica su autobiografía titulada: "Hay tiempos de hablar y tiempos de callar"?
www.redescolar.ilce.edu.mx /redescolar/efemerides/septiembre2001/conme21.htm   (857 words)

  
 LAS AMERICAS BROADBAND INC - LABN Annual Report (Small Business Issuers) (10KSB) EXHIBIT 10.2
Bustamante grants his consent for such assignment and hereby agrees to sign the Assignment Agreement and any other document required to effectuate the assignment of debt as may be reasonably requested by Las Americas Broadband.
Bustamante shall vote his shares in favor of the required amendments to the By-laws of the Company in order for them to, subject to the Conditions Precedent (as hereinafter defined), provide for the issuance of an amount equivalent to ninety percent (90%) of the total aggregate capital stock of the Company (the "Series N Shares").
Bustamante is acquiring the Consideration Shares for his own account, for investment purposes and not with a view to, or for sale in connection with, any distribution of such Consideration Shares or any part thereof, except in compliance with applicable securities laws.
sec.edgar-online.com /2004/11/17/0001091818-04-000420/section28.asp   (3594 words)

  
 Va. Day Laborer Held in Slaying Of Contractor
Carlos H. Bustamante Medieta is charged in Montgomery.
The name was Carlos H. Bustamante Medieta, and police found him Monday afternoon.
Bustamante, 29, was arrested, and Montgomery police obtained a warrant charging him with first-degree murder.
www.washingtonpost.com /wp-dyn/content/article/2005/08/30/AR2005083001670.html?nav=rss_metro/va   (766 words)

  
 innovations-report - Forum for Science, Industry and Business   (Site not responding. Last check: 2007-11-06)
Bustamante, Ryan B. Case, Nicholas R. Cozzarelli and their colleagues at Berkeley published their findings on June 3, 2004, in Science Express, which provides rapid electronic publication of selected articles from the journal Science.
Bustamante and his colleagues took note of earlier studies by another group of researchers that provided evidence that condensins appeared to induce “supercoiling” in DNA, which occurs when two helical molecules intertwine.
That perfect reproducibility strongly suggested to Bustamante and his colleagues that they were seeing a condensed structure with a well defined organization.
www.innovations-report.com /print/print_en01.php3?id=29957&ctyp=1   (894 words)

  
 Carlos Bustamante Supersite   (Site not responding. Last check: 2007-11-06)
Carlos Bustamante - Carlos Bustamante Carlos Bustamante Howard Hughes Investigator and Professor of Biochemistry and Molecular Biology and of Physics E-mail: carlos@alice.berkeley.edu Phone: (510) 643-9706 Lab Homepage:.
Carlos Bustamante - Carlos Bustamante uses novel methods of single-molecule visualization, such as scanning force microscopy, to study the structure and function of nucleoprotein assemblies.
Carlos Bustamante Essentials Born: May 6, 1951, Lima, Peru Long-Term Goal: To build a living cell.
www.lagunaquilts.com /listings/carlos-bustamante.htm   (361 words)

  
 News in the College of Letters and Science, UC Berkeley
This year, TIME Magazine has selected L&S's own Carlos Bustamante and Tim White as two of "America's Best in Science and Medicine." These faculty members share the honor with 16 other scientists and doctors specializing in fields such as astrophysics, stem cell research and pediatrics.
Carlos Bustamante, a Howard Hughes Investigator and Professor of Biochemistry and Molecular Biology in the Department of Molecular and Cell Biology, was selected for his groundbreaking research manipulating mechanically single molecules.
Tim White is a paleoanthropologist in the Department of Integrative Biology and co-director of the Laboratory for Human Evolutionary Studies.
ls.berkeley.edu /new/01/americasbest.html   (292 words)

  
 Penn State Eberly College of Science -- Pollard3-2004
Carlos Bustamante, a Howard Hughes Medical Institute Investigator and Professor of Molecular and Cell Biology, Physics, and Chemistry at the University of California at Berkeley, will present the 2004 Ernest C. Pollard Lecture at 4:00 p.m.
A brief discussion of Bustamante’s work can be found on the web at http://www.lbl.gov/Science-Articles/Research-Review/Highlights/2002/stories/biosciences/mighty.html, or at his lab’s home page: http://alice.berkeley.edu/.
Bustamante received his bachelor's degree from Cayetano Heredia University in Peru; his master's degree in biochemistry from San Marcos University in Peru; and his Ph.D. degree in biophysics from UC Berkeley, where he studied with Ignacio Tinoco, Jr.
www.science.psu.edu /alert/Pollard3-2004.htm   (406 words)

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