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Topic: Casomorphin

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	Gluten & Casein - Peptides from Casomorphin & Gliadorphin
		Both casomorphin and gliadorphin are composed of seven amino acids, which are abbreviated below.
		Casomorphin (or casomorphin) is a peptide derived from the milk protein casein.
		We suspect that these peptides may also be elevated in other disorders such as chronic fatigue, fibromyalgia and depression based on anecdotal reports of symptom remission after exclusion of wheat and dairy.
	www.greatplainslaboratory.com /gluten-casein.html (496 words)

	Compositions containing dipepitidyl peptidase IV and tyrosinase or phenylalaninase for reducing opioid-related ...
		A "casomorphin inhibitor" is a substance that inhibits the opioid-type bioactivity of casomorphin.
		A "casomorphinase" is an enzyme that inhibits the opioid-type bioactivity of casomorphin by altering the structure or composition of the casomorphin.
		In a preferred embodiment, the casomorphin inhibitors and the gluteomorphin inhibitors of the present invention are not enterically coated, which means that the inhibitors have not been treated with any specific substances to assist the passage of the inhibitors through the rigors of the stomach to the intestines.
	www.freepatentsonline.com /6251391.html (6635 words)

	Reference.com/Encyclopedia/Casomorphin
		Casomorphin is a peptide sequence that is derived from a protein found in milk and cheese called casein, and which some people consider to be addictive to humans and cause an opiate effect
		The endorphin-like activity of casomorphins in healthy individuals is generally limited to the intestines, where it may cause mild constipation in large quantities.
		In the human body casomorphins are generally broken down to inactive dipeptides by the enzyme dipeptidyl peptidase IV (DPP-IV).
	www.reference.com /browse/wiki/Casomorphin (375 words)

	Patent 6,447,772
		In another embodiment, the compositions comprise the casomorphin ligand or the gluteomorphin ligand, or the gluteomorphinase is selected from the group consisting of a tyrosinase and a phenylalaninase.
		Also preferably, the casomorphin inhibitor comprises a microbial proline peptidase and the gluteomorphin inhibitor comprises a microbial gluteomorphinase selected from the group consisting of a tyrosinase and a phenylalaninase.
		In yet still another aspect, the present invention provides compositions able to reduce the symptoms of autism in a human patient, comprising a means to inhibit casomorphin, a means to inhibit gluteomorphin, and at least one of the group consisting of a physiologically acceptable carrier, adjuvant, excipient, buffer and diluent.
	www.pharmcast.com /Patents/Yr2002/September2002/091002/6447772_Autism091002.htm (604 words)

	ANDI: Autism Network for Dietary Intervention \| Home of ANDI Bars
		Casomorphin (or caseomorphin) is a peptide derived from casein, a milk protein.
		Casein is one of the major proteins in the milk of all mammals including cows, goats, and humans.
		When Casein is digested properly, it breaks down into large peptides like casomorphin, and should then be broken down further into smaller amino acids.
	www.autismndi.com /faq/display.asp?content=FAQ&shownews=20040922164270 (391 words)

	Dietary Proteins with Neuroimmunity - BHD #341 (Site not responding. Last check: )
		Casomorphin is a peptide sequence that is derived from a protein found in milk called casein, and which some consider to be addictive to humans.
		Elevated levels of casomorphin are often discovered in the specimens of patients with neurologic disorders.
		Casomorphin is a peptide sequence that is derived from a protein found in grains called gluten, and which some consider to be addictive to humans.
	www.biodia.com /test341.html (675 words)

	Patent 6,821,514
		This is problematic because the peptides from casein and gluten, casomorphin and gluteomorphin, respectively, have opioid qualities, which means that they mimic opiates in the body (indeed, that is indicated by the "-morphin" suffix of the names, which shows their functional similarity to morphine, a strong opiate; casomorphin is also known as caseomorphine).
		Briefly, the compositions and methods comprise administering a casomorphin inhibitor and/or gluteomorphin inhibitor to a human patient in sufficient quantities to reduce the effects of the autistic disease.
		Turning to some of the other components of the compositions, the exorphin inhibitors, i.e., the casomorphin inhibitors and the gluteomorphin inhibitors, are present in the composition in adequate amounts to reduce one or more symptoms of autism in at least about one-fourth of the human patients to whom the composition is administered.
	www.pharmcast.com /Patents100/Yr2004/Nov2004/112304/6821514_Autism112304.htm (3103 words)

	www
		Researchers have found that these peptides may also be elevated in other disorders such as chronic fatigue, fibromyalgia, and depression based on anecdotal reports of symptom remission after exclusion of wheat and dairy.
		In Celiac Disease there were still antibody/gliadin complexes found in the body some 7 years after going gluten free, so it is possible that some of the peptides may not leave the body completely.
		By collecting urine samples, storing them frozen, and examining them using mass spectrometry, HPLC, or RA methods, certain opiates such as casomorphin can be detected in levels higher than those found in normals.
	www.gfcfdiet.com /TheBigFAQ's.htm (9008 words)

	Milk Linked to Autism, Schizophrenia
		This could explain several of the things one sees in autism and schizophrenia, such as hallucinations.
		If part of the brain puts out a false signal because of casomorphin, it could result in the person seeing something that's not really there; either a visual or auditory hallucination could occur.
		There are a whole number of behaviors that the rat has after beta-casomorphin-7 that are basically the same as one sees in the human with autism or schizophrenia.
	www.mercola.com /1999/archive/milk_linked_to_autism.htm (1149 words)

	Great Plains Laboratory Test Kits Ordering
		Gliadorphin has been verified by mass spectrometry techniques to be present in urine samples of children with autism.
		Casomorphin (or casomorphin) is a peptide derived from the milk protein casein.
		We suspect that these peptides may also be elevated in other disorders such as chronic fatigue, fibromyalgia and depression based on anecdotal reports of symptom remission after exclusion of wheat and dairy.
	nbnus.com /testkits/product_info.php?products_id=20&osCsid=fb06ea9d87b9ce04c2ea0fe09e061b83 (459 words)

	BioMed Central \| Full text \| Receptorphin: A conserved peptide derived from the sequence of the opioid receptor, with ...
		A similar result was equally onserved with a number of casomorphins, in the same cell lines [16,38].
		It is not actually known whether this discrepancy is due to the difference of normal and neoplastic tissue, in which a possible alternative splicing of the opioid receptor could occur, to the conditions of binding (hypotonic medium in rat brain as compared to isotonic medium in whole cell binding) or to species differences.
		Comparable maximal inhibition of growth was obtained by receptorphin and other casomorphin peptides, both in the breast and the prostate [16,38], representing possibly, the maximum opioid-related effect on these cell lines.
	www.biomedcentral.com /1471-2210/1/9 (5227 words)

	Autism Medical (Site not responding. Last check: )
		Casomorphin (or caseomorphin) is a peptide derived from casein, a milk protein.
		When Casein is digested properly, it breaks down into large peptides like casomorphin, and should then be broken down further into smaller amino acids.
		However, Dr. Reichelt in Norway, Dr. Cade at the University of Florida, and others found that urine samples from people with autism, PDD, coeliac disease, and schizophrenia contained high amounts of the casomorphin peptide in the urine.
	www.autismmedical.com /themainoffenders/?selected_menu=5 (828 words)

	Opioid peptide (Site not responding. Last check: )
		Casomorphin is a peptide sequence that is found in whey protein called casein, and which can be addictive to humans and cause an opiate effect.
		In the human digestive system, these proteins are chopped up into small segments of amino acid sequences by digestion enzymes.
		This sequence travels to the brain, where it may bind to opiate receptors and cause an effect similiar to that produced by endorphins and the other similiar peptides.
	www.neurozym.com /note_casomorfin_en.htm (175 words)

	Casomorphin (Site not responding. Last check: )
		morphine on related to morphine pictures Casomorphin morphine is is required by mg morphine by lyrics morphine.
		dose morphine is required for information on morphine into morphine treatment Casomorphin morphine pumps or morphine street names, morphine with cannot be picture of morphine with acting morphine - morphine induced by morphine ir to make morphine cannot be symptoms of morphine or morphine metabolism features.
		Get info on lorazepam, also known as doxycycline either cipro, casomorphin to amitriptyline (morphine in the) cozaar depends on morphine dosage.
	www.tabbox.net /morphine/casomorphin.html (869 words)

	AFH LIBRARY - NotMilk - Autism and ADD
		Casomorphine is a derivative of casein, which is a milk protein.
		Here are some abstracts, from a diverse group of researchers, on the effects of milk-derived opioids known as casomorphins on the immune system and brain, so you might be more informed on the possible effects these have on your child.
		They are identical to casomorphin and gliadomorphin and go away after dietary elimination (it may take 1 year to normalize).
	www.alkalizeforhealth.net /Lnotmilk5.htm (4348 words)

	Autism \| ß-Casomorphin Induces Fos-Like Immunoreactivity in Discrete Brain Regions Relevant to Schizophrenia and ...
		The purpose of this study was to determine the brain areas that are influenced by casomorphine.
		Rats were injected with one form of casomorphine, and their brains were examined to see which areas were activated, as compared to rats that didnât receive the casomorphine.
		The results show that the brain regions that were activated by casomorphine were also among those that are affected in people with schizophrenia or autism.
	autism.healingthresholds.com /research/ss-casomorphin-induces-fos-like- (208 words)

	Vegetarians in Paradise/ A2 Milk/A1 Milk/Heart Disease/Diabetes/Beta Casomorphin 7
		Milk in Iceland came from an ancient Norske breed of cow that was not A1.
		Further research by Elliot led to the discovery of beta casomorphin 7 (BCM-7) that was implicated in heart disease and Type 1 diabetes.
		However, it is believed on the basis of what is known in general about immune responses that the A1 variant may induce other immune responses of importance to the health of individuals.
	www.vegparadise.com /news35.html (1534 words)

	Enzyme FAQs
		DPP IV is one of only two enzymes that can break apart Casomorphin molecules, which are otherwise highly resistant to being broken apart.
		These peptidases work to specifically break down certain exorphin peptides that are normally resistant to proteolysis, such as casomorphin and gliadin.
		Protease and papain, which are sulfite-free, contribute high levels of non-specific protein-degrading activity over a broad pH range, and work synergistically with the peptidase to increase the break down of food proteins.
	autismcoach.com /Enzyme_FAQs.htm (2552 words)

	V1:Ch1 Bioactive peptides derived from whey proteins
		It seems likely that casomorphins participate in the control of gastrointestinal function in adults (Tome et al., 1987).
		Casomorphins have been found to prolong gastrointestinal transit time and exert antidiarrhoeal action (Daniel et al.,1991).
		The physiological significance of opioid peptides may be different in pregnant, puerperal women and in neonates.
	www.msstate.edu /org/fsfa/Vol1/2-Pihlanto.htm (4835 words)

	Clinical Trial: Assessing the Presence of Casomorphins in Human Plasma After Dairy Ingestion
		This purpose of this study is to perform a pilot investigation to determine if opioid peptides such as casomorphin can be detected in human plasma after cheese ingestion.
		Casomorphin receptor binding has been demonstrated in opiate receptor assays and bioassays.
		The ability of casein-derived opioid peptides to pass into the bloodstream is not well characterized, and is the subject of the present study.
	www.clinicaltrials.gov /show/NCT00360919 (456 words)

	Health (Site not responding. Last check: )
		A woman cured her son of autism by eliminating all milk/dairy/wheat from the child's diet.
		Casomorphin (milk products) probable cause of ADD and autism.
		Beta-casomorphin-7 was found in high concentration in the blood of patients with either schizophrenia or autism.
	www.angelfire.com /freak2/liquidmeat/milk3.html (130 words)

	Casomorphin and Exorphines
		Casomorphine is derived from the digestion of casein and exorphine from the digestion of gluten.
		Casomorphine and exorphines which are provided by milk proteins and cereals respectively, can trigger behaviour in dogs not unlike giving them morphine or other opiates.
		There has been a lot of research done on this with autistic children and schizophrenics and they have found that they can interfere with the activity of neurotransmitters.
	www.weimaranerforum.org /viewtopic.php?p=37355 (371 words)

	VegSource Article
		If you examined a casein molecule under a powerful microscope, it would look like a long chain of beads (the "beads" are amino acids-simple building blocks that combine to make up all the proteins in your body).
		When you drink a glass of milk or eat a slice of cheese, stomach acid and intestinal bacteria snip the casein molecular chains into casomorphins of various lengths.
		Like it or not, mother's milk has a drug-like effect on the baby's brain that ensures that the baby will bond with Mom and continue to nurse and get the nutrients all babies need.
	www.vegsource.com /articles2/barnard_food_seduction.htm (1585 words)

	ANDI: Autism Network for Dietary Intervention \| Home of ANDI Bars
		Some people also think that one of the natural pigments in corn (lutein) might cause problems for reasons that are not properly understood (see: "Sara's Diet").
		Cade: "Beta Casomorphin induces FOS like immunoreactivity in discrete brain regions relevant to schizophrenia and autism" and "A peptide found in schizophrenia and autism causes behavioral changes in rats."
		Researchers report that the same problem occurs with human casomorphin, and we have had several letters from mothers who said that the child did not improve until he was weaned.
	www.autismndi.com /faq (17700 words)

	Milk Bioactive Peptides and {beta}-Casomorphins Induce Mucus Release in Rat Jejunum -- Trompette et al. 133 (11): 3499 ...
		The intestinal mucus gel covering the mucosal surface is a major
		casomorphins on mucus secretion is their entry in the submucosal
		Deplancke, B. & Gaskins, H. (2001) Microbial modulation of innate defense: goblet cells and the intestinal mucus layer.
	jn.nutrition.org /cgi/content/full/133/11/3499 (2783 words)

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