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Topic: Cell adhesion molecule

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	Cell adhesion - Wikipedia, the free encyclopedia
		Cells are often not found in isolation, rather they tend to stick to other cells or non-cellular components of their environment.
		Cell adhesion generally involves protein molecules at the surface of cells, so the study of cell adhesion involves cell adhesion proteins and the molecules that they bind to.
		Cell adhesion proteins hold synapses together and the regulation of synaptic adhesion is involved in learning and memory.
	en.wikipedia.org /wiki/Cell_adhesion (505 words)

	VCAM1 - vascular cell adhesion molecule 1
		The aim of this study was to determine circulating levels of adhesion molecules in serum from patients with congenital diaphragmatic hernia (CDH) to investigate the relationship between soluble ICAM-1, ELAM-1, and VCAM-1 liberated by activated vascular endothelium and the development of persistent pulmonary hypertension (PPH) in patients with CDH.
		Since cell adhesion molecules are involved in this process, investigations on the expression of intercellular adhesion molecule-1, endothelial leukocyte adhesion molecule-1, vascular cell adhesion molecule-1, and platelet endothelial cell adhesion molecule in the lower uterine segment and in vitro experiments on human umbilical vein endothelial cells were performed.
		Stimulation of human umbilical vein endothelial cells by VEGF or bFGF for 18 h up-regulated intercellular adhesion molecule 1 and vascular cell adhesion molecule 1 expression and significantly increased PMNL adhesion and TEM in response to complement fragment 5a (C5a) or interleukin (IL)-8.
	www.ihop-net.org /UniPub/iHOP/gg/93044.html (3863 words)

	NRCAM - neuronal cell adhesion molecule
		The neuronal cell adhesion molecule Bravo/Nr-CAM is a cell surface protein of the immunoglobulin (Ig) superfamily and is closely related to the L1/NgCAM and neurofascin molecules, all of which contain six immunoglobulin domains, five fibronectin repeats, a transmembrane region, and an intracellular domain.
		Neuronal cell adhesion molecule (NCAM) decreased in pyriform cortex and amygdala of kindled rats, indicating neuronal degeneration.
		It is caused by mutations in L1CAM that encodes a multifunctional transmembrane neuronal cell adhesion molecule.
	www.ihop-net.org /UniPub/iHOP/gg/90670.html (2768 words)

	Adhesion molecules
		Thus, the white blood cells lack the entire family of beta-2 receptors needed to bind to endothelial cells.
		ICAM (intercellular adhesion molecules) may be expressed on activated endothelial cells.
		White blood cells have alpha1 and beta 2 integrins that bind to endothelial cells
	cellbio.utmb.edu /cellbio/adhesion_molecules.htm (656 words)

	Neural Cell Adhesion Molecule Contributes to Hemopoiesis-Supporting Capacity of Stromal Cell Lines -- Wang et al. 23 ...
		that neural cell adherion molecule (NCAM) is the molecule that
		NCAM is the Molecule That Reacts with Anti-PA6 Antibody
		NCAM, a neural cell adhesion molecule of the Ig superfamily,
	stemcells.alphamedpress.org /cgi/content/full/23/9/1389 (5980 words)

	Cell adhesion molecule - Wikipedia, the free encyclopedia
		Cell Adhesion Molecules (CAMs) are proteins located on the cell surface involved with the binding with other cells or with the extracellular matrix (ECM) in the process called cell adhesion.
		A member of the Ig superfamily of cell adhesion molecules, L1 is posited in the CNS to mediate cell-cell interactions in developing tissue and adult tissue.
		Cell cultures using aggregation assays have demonstrated the disruptive effects of ethanol on L1-mediated cell-cell adhesion, at concentrations of ethanol that are clinically relevant, in NG108-15 neuroblastoma x glioma hybrid cells, cerebellar granule cells, and murine fibroblasts transfected with human L1 (67, 68, 70).
	en.wikipedia.org /wiki/Cell_adhesion_molecule (579 words)

	Fimbria-Dependent Activation of Cell Adhesion Molecule Expression in Porphyromonas gingivalis-Infected Endothelial ... (Site not responding. Last check: 2007-10-04)
		in the induction of cell adhesion molecule expression in endothelial
		Cells were harvested at 2, 24, and 48 h for FACS analysis for the detection of ICAM-1 (A) and VCAM-1 (B) expression.
		Cells were harvested at 2 h for FACS analysis (upper panels) or confocal microscopy (lower panels) for the detection of P-selectin (A) and E-selectin (B) expression.
	iai.asm.org /cgi/content/full/70/1/257 (4990 words)

	QED Cell Adhesion Molecule Antibodies
		Cell adhesion molecules regulate cell-cell and cell-matrix interactions that are fundamental to cell growth, differentiation and proliferation, migration, and regeneration.
		QED offers an extensive panel of monoclonal antibodies to human cell adhesion molecules that can be used to identify and analyze these multi-functional proteins.
		This chicken antibody recognizes human fibronectin, a 440 kD cell matrix protein that binds to cell surfaces and to collagen, fibrin, heparin, DNA, and actin.
	www.qedbio.com /adhesion.htm (409 words)

	Platelet endothelial cell adhesion molecule-1 (PECAM-1) & coronary heart disease Indian Journal of Medical Research ...
		Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a 130-kDa member of the immunoglobulin superfamily of cell adhesion molecules.
		In addition to its role in vascular cell adhesion, there is growing evidence that PECAM-I can transduce signals that suppress programmed cell death which is thought to be via its ability to inhibit cytochrome C release from mitochondria after exposure of cells to a wide range of cytotoxic stimuli3.
		PECAM-1 however is no ordinary adhesion molecules with its wide variety of functions in platelet activation, inflammation, cell survival, and the immune response.
	www.findarticles.com /p/articles/mi_qa3867/is_200502/ai_n13486989 (853 words)

	PROW Guide: L1 cell adhesion molecule (CD171)
		The cell adhesion molecule L1 is developmentally regulated in the renal epithelium and is involved in kidney branching morphogenesis.
		Heterophilic binding of L1 on unmyelinated sensory axons mediates Schwann cell adhesion and is required for axonal survival.
		Expression and regulation of the neural cell adhesion molecule L1 on human cells of myelomonocytic and lymphoid origin.
	mpr.nci.nih.gov /prow/guide/1813332452_g.htm (1681 words)

	The Spermatogenic Ig Superfamily/Synaptic Cell Adhesion Molecule Mast-Cell Adhesion Molecule Promotes Interaction with ... (Site not responding. Last check: 2007-10-04)
		a homophilic adhesion molecule that spans the synaptic cleft
		cell (indicated by an arrowhead) and in an adjacent segmental portion (rectangle) of an SCG neurite.
		Contribution of the SgIGSF adhesion molecule to survival of cultured mast cells in vivo.
	www.jimmunol.org /cgi/content/full/174/11/6934 (5543 words)

	InterPro: IPR003989 Vascular cell adhesion molecule-1 (Site not responding. Last check: 2007-10-04)
		IPR003987 Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal
		Intercellular adhesion molecules (ICAMs) and vascular cell adhesion molecule-1 (VCAM-1) are part of the immunoglobulin superfamily.
		Cellular component is the part of a cell of which a gene product is a component; GO includes the extracellular environment of cells; a gene product may be a component of one or more parts of a cell.
	www.ebi.ac.uk /interpro/IEntry?ac=IPR003989 (3432 words)

	InterPro: IPR003988 Intercellular adhesion molecule
		It is expressed on leucocytes, endothelial and epithelial cells, and is upregulated in response to bacterial invasion.
		The protein is refractory to proinflammatory cytokines, and plays an important role in the adhesion of leucocytes to the uninduced endothelium [ 4 ].
		It is associated with the RBC Rh antigens and could be important in retaining immature red cells in the bone marrow, or in the uptake of senescent cells into the spleen [ 6 ].
	www.ebi.ac.uk /interpro/IEntry?ac=IPR003988 (3675 words)

	A Chimeric Cell Adhesion Molecule Mediates Homing of Lymphocytes to Vascularized Tumors -- Wiedle et al. 59 (20): 5255 ... (Site not responding. Last check: 2007-10-04)
		adhesion of lymphoid cells to soluble recombinant integrin
		Adhesion of J558/KISS31 and J558/CD31 cells to tend.1 endothelioma monolayers.
		Piali L., Fichtel A., Terpe H. J., Imhof B. A., Gisler R. Endothelial vascular cell adhesion molecule 1 expression is suppressed by melanoma and carcinoma.
	cancerres.aacrjournals.org /cgi/content/full/59/20/5255 (5652 words)

	Human Blastocysts and Endometrial Epithelial Cells Express Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) -- ... (Site not responding. Last check: 2007-10-04)
		Typical histogram of flow cytometry analysis of endometrial epithelial cells that were freshly isolated from a woman in the secretory phase (cycle d 20).
		ALCAM mRNA at 4.7 kbp (arrow) was detected in the RNAs derived from the endometrial epithelial cell fraction in the proliferative phase (lane 4) and secretory phase (lanes 5 and 6, cycle d 20 and 24).
		on hematopoietic stem cells and endothelial progenitors (30,
	jcem.endojournals.org /cgi/content/full/88/7/3437 (3994 words)

	Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) Homophilic Adhesion Is Mediated by Immunoglobulin-like Domains ... (Site not responding. Last check: 2007-10-04)
		Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) Homophilic Adhesion Is Mediated by Immunoglobulin-like Domains 1and 2and Depends on the Cytoplasmic Domain and the Level of Surface Expression -- Sun et al.
		Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) Homophilic Adhesion Is Mediated by Immunoglobulin-like Domains 1 and 2 and Depends on the Cytoplasmic Domain and the Level of Surface Expression
		PECAM-1/CD31 is vascular cell adhesion and signaling molecule of the Ig superfamily that plays a role in neutrophil recruitment at inflammatory sites and may be involved the release of leukocytes from the bone marrow and in cardiovascular development.
	www.jbc.org /cgi/content/abstract/271/31/18561 (1696 words)

	Medical Dictionary: Cell adhesion molecule - WrongDiagnosis.com
		Cell adhesion molecule : diverse family of extracellular (e.g., laminin) and cell surface (e.g., NCAM) glycoproteins involved in cell\-cell and cell\-extracellular matrix adhesion, recognition, activation, and migration.
		The term Cell adhesion molecule can be used for:
		The description of Cell adhesion molecule may also be used for the following terms:
	www.wrongdiagnosis.com /medical/cell_adhesion_molecule.htm (197 words)

	Adhesion molecules
		E-selectin: Mediates initial PMN adhesion to endothelial cells
		B cells (Activated); T cells (Activated and γδ);
		Homophilic: Neural specific Ig Cell Adhesion molecules (IgCAMs)
	www.neuro.wustl.edu /neuromuscular/lab/adhesion.htm (218 words)

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