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Topic: Cell bodies


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In the News (Sat 19 Dec 09)

  
  Dopamine and lewy bodies
Alpha-synuclein co-exists with lipids in the Lewy bodies, a pathological hallmark of Parkinson's disease.
One of the key regulators of cell cycle progression is the retinoblastoma protein (pRb); therefore, we assessed the staining for pRb and its inactive hyperphosphorylated isoform, ppRb, in autopsy tissue from patients with PD. In PD we found abundant pRb staining in neuronal cytoplasm of the substantia nigra, mid-frontal cortex, and hippocampus by immunohistochemistry.
A pathologic hallmark is the presence of cytoplasmic eosinophilic inclusions (Lewy bodies) in monoamine neurons.
lansbury.bwh.harvard.edu /da_and_lewy_bodies.htm   (9709 words)

  
 Neurons and Support Cells
The conspicuous nerve cell bodies in the ventral horn belong to spinal motor neurons.
Motor axons originate with cell bodies in the spinal cord's ventral horn or in the brainstem's motor nuclei or in peripheral sympathetic or parasympathetic ganglia.
Pyramidal cells are the efferent (long-axon) cells of the cerebral cortex.
www.siumed.edu /~dking2/ssb/neuron.htm   (8840 words)

  
 Neurons / Neuroglial Cells
Nissl bodies are prominent in the cytoplasm of the soma and proximal parts of dendrites.
Their cell bodies are located in the retina, the olfactory epithelium, and the cochlear and vestibular ganglia.
A dark nucleolus is present in the nucleus of the neuron and clumps of rough endoplasmic reticulum are faintly visible in the cytoplasm.
www.sci.uidaho.edu /med532/neurons_neuroglial_cells_module1.htm   (608 words)

  
 Neuroscience For Kids - cells of the nervous system
Cells of the nervous system, called nerve cells or neurons, are specialized to carry "messages" through an electrochemical process.
Some of the biggest neurons have cell bodies that are 100 microns wide.
Neurons are the oldest and longest cells in the body!
faculty.washington.edu /chudler/cells.html   (681 words)

  
 Glossary [Stem Cell Information]
The blastocyst is a sphere made up of an outer layer of cells (the trophoblast), a fluid-filled cavity (the blastocoel), and a cluster of cells on the interior (the inner cell mass).
When it is used to refer to cells grown in a tissue culture dish, a clone is a line of cells that is genetically identical to the originating cell.
By combining a patient's somatic cell nucleus and an enucleated egg, a scientist may harvest embryonic stem cells from the resulting embryo that can be used to generate tissues that match a patient's body.
stemcells.nih.gov /info/glossary.asp   (1853 words)

  
 Ganglion cell - Wikipedia, the free encyclopedia
A ganglion cell (sometimes called a gangliocyte) is a type of neuron located in the retina of the eye that receives visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells.
These cells are known as midget retinal ganglion cells, based on the small sizes of their dendritic trees and cell bodies.
These cells are known as parasol retinal ganglion cells, based on the large sizes of their dendritic trees and cell bodies.
en.wikipedia.org /wiki/Ganglion_cell   (644 words)

  
 Webvision: Amacrine cells
The dopaminergic amacrine cell types have been revealed by immunostaining with an antibody directed against tyrosine hydroxylase (TOH)(the rate limiting enzyme for dopamine), is a wide-field cell that stratifies almost exclusively in stratum 1 of the IPL (under the amacrine cell bodies).
The major output of the A18 cell is in the fine network of dendrites and axon terminals surrounding the cell bodies and apical dendrites of AII and A8 cells (Kolb et al., 1991).
The dopamine cell is, however, primarily an amacrine cell and not an interplexiform cell, in the mammalian retina, thus their effect on inner retina circuitry would be expected to be more pronounced than on outer retina.
webvision.med.utah.edu /amacrines3.html   (3966 words)

  
 The Movement of Coiled Bodies Visualized in Living Plant Cells by the Green Fluorescent Protein -- Boudonck et al. 10 ...
coiled bodies in the nucleolus, in the nucleoplasm, and from the
Coiled body marked with an arrow moves from the periphery of the nucleoplasm to the periphery of the nucleolus, after which it moves along the periphery of the nucleolus and finally fuses with another coiled body.
Carmo-Fonseca, M., Ferreira, J., and Lamond, A.I. Assembly of snRNP-containing coiled bodies is regulated in interphase and mitosis-evidence that the coiled body is a kinetic nuclear structure.
www.molbiolcell.org /cgi/content/full/10/7/2297   (6434 words)

  
 Cellular22-44
Fibrous astrocytes (f) are less branched and their processes radiate from the cell body for considerable distances whereas protoplasmic astrocytes (P) have more numerous and profusely branched processes.
This 'volume-rendered' image of a living cell is one of a series that allows us to see fluorescently-labelled packets of neurotransmitters (chemical messengers of the nervous system) in four dimensions as they move around the cell.
The neurotransmitter acetylcholine (stained red) is released by the nerve cells to transmit its signals to the muscle and serves in this confocal image to highlight the region of the neuromuscular junction.
www.coloradocollege.edu /idprog/Neuroscience/Cellular22-44.html   (917 words)

  
 Golgi Bodies   (Site not responding. Last check: 2007-11-04)
Golgi bodies, named after the Italian biologist Camillo Golgi, are composed of a stack of about half a dozen sacuoles, whose purpose in the cell are to prepare and store chemical products produced in the cell, and then to secrete these outside the cell.
Golgi bodies are formed when small sac like pieces of membrane are pinched away from the cell.
A portion of materials in the wall of a plant cell are assembled in the Golgi bodies.
www.cdli.ca /~dpower/cell/golgi.htm   (184 words)

  
 Trafficking of Cholesterol from Cell Bodies to Distal Axons in Niemann Pick C1-deficient Neurons -- Karten et al. 278 ...
The expression of NPC1 and LAMP1 was visualized by immunocytochemistry and confocal microscopy in cell bodies (A and B) and distal axons (D and E).
5) was transported from cell bodies to distal axons (Fig.
are restricted to neuronal cell bodies (62, 68).
www.jbc.org /cgi/content/full/278/6/4168   (6198 words)

  
 Nuclear Domains Enriched in RNA 3'-processing Factors Associate with Coiled Bodies and Histone Genes in a Cell ...
Cells were dehydrated by subsequent incubations in 70, 90, and 100% ice-cold ethanol for 4 min per incubation and air dried.
Cells synchronized by mitotic shake-off (mso) and hydroxyurea (hu) treatment revealed that the spatial association between coiled bodies and cleavage bodies is cell cycle dependent.
G1 cells were analyzed 4 h after mso; S phase cells were analyzed 10 h after mso or 4 h after release from hu block; and G2 cells were analyzed 8 h after release from hu block.
www.molbiolcell.org /cgi/content/full/10/11/3815   (6187 words)

  
 UGA Cellular Biology | Faculty | Marcus Fechheimer
Molecular cloning, expression, and mutagenesis are being employed to dissect the interactions among cytoskeletal proteins in vitro and in living cells.
In addition, homologous recombination is employed to create cell lines with specific defects in single genes in order to test the roles of these proteins in cell structure and movement.
Dictyostelium discoideum cells lacking the 34,000 dalton actin binding protein can grow, locomote, and develop, but exhibit defects in regulation of cell structure and movement: a case of partial redundancy.
www.uga.edu /cellbio/fechheimer.html   (688 words)

  
 Elke Stein - Yale Cell Biology
One of the earliest steps in neuronal development is the growth of axons from their cell bodies of origin to their appropriate targets, to form a precise pattern of neuronal connections.
Recent progress in the field lead to the identification of several families of attractants and repellents, including the netrin, semaphorin and slit protein families, as well as receptors involved in mediating the responses of these factors, however only little is known how these guidance cues function in vivo.
To address this we are using a series of biochemical, cell biological and molecular techniques, in combination with functional approaches, including an axon turning assays utilizing Xenopus spinal and neuronal rodent cultures, in vitro explant and slice cultures, and in vivo assays using the developing chicken as a model.
www.cellbiology.yale.edu /cellbio/html/faculty/e_stein.shtml   (499 words)

  
 Synapse Formation in the Absence of Cell Bodies Requires Protein Synthesis -- Schacher and Wu 22 (5): 1831 -- Journal ...
EPSPs are evoked by stimulating the SN cell body and recording the response with an intracellular electrode in the new L7 stump (arrow).
Increases in synaptic efficacy proceeds in the absence of all cell bodies.
Proteins synthesized in the cell bodies of SN and L7 that are critical for synaptic function and transported toward synaptic
www.jneurosci.org /cgi/content/full/22/5/1831   (5458 words)

  
 MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies - Nature Cell Biology   (Site not responding. Last check: 2007-11-04)
Whereas siRNA-directed mRNA cleavage is increasingly understood, the mechanisms by which miRNAs repress protein synthesis are obscure.
Recent studies have revealed the existence of specific cytoplasmic foci, referred to herein as processing bodies (P-bodies), which contain untranslated mRNAs and can serve as sites of mRNA degradation
Here we demonstrate that Argonaute proteins — the signature components of the RNA interference (RNAi) effector complex, RISC — localize to mammalian P-bodies.
www.nature.com /ncb/journal/v7/n7/abs/ncb1274.html   (302 words)

  
 Medical Dictionary: Red cell inclusion bodies - WrongDiagnosis.com
Medical Dictionary: Red cell inclusion bodies - WrongDiagnosis.com
Red cell inclusion bodies: Pathologic inclusions occurring in erythrocytes.
Terms that may be interchangeable with Red cell inclusion bodies:
www.wrongdiagnosis.com /medical/red_cell_inclusion_bodies.htm   (174 words)

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