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Topic: Cell growth

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In the News (Mon 18 Feb 19)

  Cell growth
Researchers studying the molecular mechanisms that control cell growth and division are piecing together a surprising and complicated regulatory system that offers promising targets for anticancer drugs.
The study, published August 11 in the journal Cell, represents an important step toward understanding the complex network of signals that controls the "cell cycle"--the orderly sequence of events that all cells pass through as they grow to a certain size, copy their chromosomes, and divide into two new cells.
Cell cycle control is one of the hottest areas of biomedical research, in part because of the potential applications in fighting cancer, which results from uncontrolled proliferation of cells in the body.
currents.ucsc.edu /05-06/08-22/cell.asp   (629 words)

 Cell Growth - Doubling Up
This process is usually referred to as the "cell cycle." In embryos and young children the cell cycle is shorter than it is in adults.
In adults, only a small fraction of the cells are in a growth state at any one time—except for cells in organs like the skin and bone marrow that are continuously producing new cells.
Actual cell division is called mitosis and is called the "M stage." When a mother cell divides into two daughter cells, the daughter cells often enter what is termed the "G1" or "gap" stage.
www.chemheritage.org /EducationalServices/pharm/chemo/activity/double.htm   (657 words)

 (WO/1991/010738) T CELL GROWTH FACTOR
The present invention relates to a mammalian T cell growth factor which comprises a protein which supports, or is capable of supporting, interleukin 2 (IL2)-independent and interleukin 4 (IL4)-independent growth of helper T cells in the absence of antigen.
The T cell growth factor P40 is contemplated herein 5 to be useful in stimulating the proliferation of T helper cells in mammals.
A number of cell lines suitable for fusion have been developed, and the choice of any particular line for hybridization protocols is directed by any one of a number of criteria such as speed, uniformity of growth characteristics, deficiency of its metabolism for a component of the growth medium, and potential for good fusion frequency.
www.wipo.int /pctdb/en/wo.jsp?WO=1991/10738&IA=WO1991/10738&DISPLAY=DESC   (16445 words)

 Coupling the cell cycle to cell growth
For example, whereas the addition of penicillin to a culture of growing Escherichia coli cells inhibits cell division, the cells continue to grow and elongate into filaments, DNA replication continues, and the proper segregation of the daughter chromosomes is not affected (Fig.
The system is regulated by the conditions under which the cells are grown; that is, the growth medium determines the growth rate of a culture, which in turn dictates the frequency of all cell-cycle-related events (Jensen and Pedersen, 1990; Marr, 1991).
Not only is it counterintuitive that a cell uses a crude and chemically ill-defined parameter such as cell mass to regulate its progress through the cell cycle, but it seems likely that a central molecular parameter—or set of parameters—that reflects the growth state of the cell is used for such vital and flexible regulatory processes.
www.nature.com /embor/journal/v4/n8/full/embor895.html   (3420 words)

The DNA in a human cell is estimated to consist of six billion pairs of nucleotides.
Cell division is the process by which cells produce offspring cells.
Growth factors stimulate growth and division of cells.
www.methuen.k12.ma.us /mnmelan/cell_growth_and_division224.htm   (775 words)

 Development balances cell growth and death.
This cell cycle of growth and rest is controlled by "checkpoint" molecules first characterized in the 1980s and 1990s in yeast, and then in other eukaryotes.
This phenomenon of programmed cell death or cell suicide is called apoptosis and is not the same as death due to injury or damage.
DNA and proteins are the molecules of the cell nucleus.
www.dnaftb.org /dnaftb/text/38/index.html   (3304 words)

 Cell Growth & Differentiation -- Terms and Conditions for Use
Failure to comply with the foregoing restrictions and unauthorized duplication of any portion of these materials are a violation of applicable laws and may be subject to criminal prosecution and civil penalties.
The person using Cell Growth & Differentiation Online may view, reproduce or store copies of articles comprising the journal provided that the articles are used only for their personal, non-commercial use.
Cell Growth & Differentiation Online is under development and changes may be made in these publications and programs at any time.
cgd.aacrjournals.org /misc/terms.shtml   (673 words)

  Marijuana might cause new cell growth in the brain - health - 13 October 2005 - New Scientist
In mammals, new nerve cells are constantly being produced in a part of the brain called the hippocampus, which is associated with learning, memory, anxiety and depression.
A previous study showed that the antidepressant fluoxetine (Prozac) also increases new cell growth, and the results indicated that it was this cell growth that caused Prozac’s anti-anxiety effect.
When neurogenesis was halted in these rats using X-rays, this effect disappeared, indicating that the new cell growth might be responsible for the behavioural changes.
www.newscientist.com /article.ns?id=dn8155   (478 words)

  The Eukaryotic Cell Cycle
Although cell growth is usually a continuous process, DNA is synthesized during only one phase of the cell cycle, and the replicated chromosomes are then distributed to daughter nuclei by a complex series of events preceding cell division.
The proliferation of these cells is triggered by platelet-derived growth factor, which is released from blood platelets during clotting and signals the proliferation of fibroblasts in the vicinity of the injured tissue.
Several cell cycle checkpoints function to ensure that incomplete or damaged chromosomes are not replicated and passed on to daughter cells (Figure 14.8).
www.ncbi.nlm.nih.gov /books/bv.fcgi?tool=bookshelf&call=bv.View..ShowSection&searchterm=cell&rid=cooper.section.2433   (2749 words)

 Cell growth Summary
Growth media can also be tailored to favor the growth of one or a few types of bacteria over the many other types of bacteria that would develop on a nonselective medium, or to provide an enriched environment for those bacteria that would other wise grow poorly or very slowly.
When used in the context of reproduction of living cells the phrase "cell growth" is shorthand for the idea of "growth in cell populations by means of cell reproduction." During cell reproduction one cell (the "parental" cell) divides to produce two daughter cells.
Large cells that are primarily for nutrient storage can have a smooth surface membrane, but metabolically active large cells often have some sort of folding of the cell surface membrane in order to increase the surface area available for transport functions.
www.bookrags.com /Cell_growth   (3338 words)

 Growth of Bacterial Populations
The exponential phase of growth is a pattern of balanced growth wherein all the cells are dividing regularly by binary fission, and are growing by geometric progression.
Thus, the chemostat relieves the insufficiency of nutrients, the accumulation of toxic substances, and the accumulation of excess cells in the culture, which are the parameters that initiate the stationary phase of the growth cycle.
Studying the growth of bacterial populations in batch or continuous cultures does not permit any conclusions about the growth behavior of individual cells, because the distribution of cell size (and hence cell age) among the members of the population is completely random.
textbookofbacteriology.net /growth.html   (2317 words)

The Lab of Cell Growth is going to send their T-Cell experiment into outer space.
Growth is induced by altering cell signaling and gene expression.
We have several on-going research projects, which include investigating the role of dietary fatty acids in prostate cancer cell growth, the response of osteoblasts to mechanical loading and the signal transduction cascades and gene expression occurring during T-cell activation.
www.spacedu.com   (177 words)

 Oncogene - cFos is critical for MCF-7 breast cancer cell growth
The MCF-7 Tam/Fos (clones #28 and #73), Tam/Squelcher (clones #25 and #44), and vector-transfected cells (clone #1) were cultured in the presence or absence of DOX to block or induce the expression of Tam/Fos or Tam/Squelcher.
The transfected cells were then split and plated as single cells that were then allowed to grow for three to five doublings to form colonies.
In addition to its role in normal development and cellular growth, the cFos protein is associated with apoptotic cell death in antiproliferative conditions, and in response to cellular injury (Preston et al.
www.nature.com /onc/journal/v24/n43/full/1208905a.html   (5010 words)

 Modeling Stem Cell Population Growth: Incorporating Terms for Proliferative Heterogeneity -- Deasy et al. 21 (5): 536 ...
Asymmetric cell kinetics genes: the key to expansion of adult stem cells in culture.
Cell proliferation kinetics of normal and tumour tissue in vitro: quiescent reproductive cells and the cycling reproductive fraction.
Steel G. Growth kinetics of tumours: cell population kinetics in relation to the growth and treatment of cancer.
stemcells.alphamedpress.org /cgi/content/full/21/5/536   (4490 words)

 Cancer Cell Online
Normal myoepithelial cells in the basal layer are positive for cytokeratin 5, whereas a subset of tumor epithelial cells are p53 positive.
Double-positive cells in the basal layer are abnormal myoepithelial cells.
We report here that in human cancer cells, the function of kinase-independent EGFR is to prevent autophagic cell death by maintaining intracellular glucose level through interaction and stabilization of the sodium/glucose cotransporter 1 (SGLT1).
www.cancercell.org   (544 words)

 Distinct and sequential upregulation of genes regulating cell growth and cell cycle progression during hepatic ...
Distinct and sequential upregulation of genes regulating cell growth and cell cycle progression during hepatic ischemia-reperfusion injury -- Barone et al.
injury in tumor cells and in kidney IRI (22, 35, 41, 44).
the cell cycle and with the onset of cell proliferation (38).
ajpcell.physiology.org /cgi/content/full/289/4/C826   (5653 words)

 Cannabidiol Dramatically Inhibits Breast Cancer Cell Growth, Study Says - NORML
Compounds in marijuana inhibit cancer cell growth in animals and in culture on a wide range of tumoral cell lines, including human breast carcinoma cells, human prostate carcimona cells, and human colectoral carcinoma cells, according to preclinical trial data published in the May issue of the Journal of Pharmacology and Experimental Therapeutics.
Previous studies have shown cannabinoids to reduce the size and halt the spread of glioma (brain tumor) cells in animals and humans in a dose dependent manner.
Separate preclinical studies have also demonstrated cannabinoids to inhibit cancer cell growth and selectively trigger malignant cell death in skin cancer cells, leukemic cells, lung cancer cells, and prostate carcinoma cells, among other cancerous cell lines.
norml.org /index.cfm?Group_ID=6917   (434 words)

 CELLS alive! Cell Cams
These are a bit different from "livecams" you might find elsewhere on the web - these repeat at daily or shorter intervals in order to convey information on biological rhythms.
This 24 hour series begins every midnight and shows cell division in a population of cultured cancer cells.
cell division, mitosis, meiosis, cell cycle, cancer, exponential growth, lag phase, log phase, stationary phase, time lapse photography
www.cellsalive.com /cam0.htm   (155 words)

 Omega-6 fatty acids cause prostate tumor cell growth in culture
The study was led by Millie Hughes-Fulford, PhD, director of the Laboratory of Cell Growth at SFVAMC and scientific advisor to the U.S. Undersecretary of Health for the Department of Veterans Affairs.
Working with human prostate cancer cells in tissue culture, Hughes-Fulford and her fellow researchers identified for the first time a direct chain of causation: When introduced into prostate tumor cells in culture, omega-6 fatty acid causes the production of cPLA2, which then causes the production of the enzyme COX2.
These drugs have been shown to be effective against tumor growth as well as in treating the pain associated with inflammatory conditions such as arthritis, but have been implicated in increased risk of cardiovascular problems in people who take them regularly.
www.medicalnewstoday.com /medicalnews.php?newsid=29976   (834 words)

draw a growth curve and explain what is occuring during the growth cycle of a bacterial population in batch culture
Growth yield is the amount of cells produced at end of exponential growth
Describe three ways in which our current knowledge of encouraging microbial growth affects something in your life and three ways in which our current knowledge of interfering with microbial growth affects something in your life.
biology.fullerton.edu /biol302/growth.html   (323 words)

 Molecular Profile and Partial Functional Analysis of Novel Endothelial Cell-Derived Growth Factors that Regulate ...
cell engraftment was significantly higher in the nonobese diabetic severe combined immunodeficient (NOD/SCID) mice transplanted with the progeny of noncontact HUBEC cultures compared with either input or the progeny of TSF cultures.
Umbilical cord blood cells capable of engrafting in primary, secondary, and tertiary xenogeneic hosts are preserved after ex vivo culture in a non-contact system.
Wang J, Doedens M, Dick J. Primitive human hematopoietic cells are enriched in cord blood compared with adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo SCID-repopulating cell assay.
stemcells.alphamedpress.org /cgi/content/full/24/5/1315   (6341 words)

 Do No Harm: The Coalition of Americans for Research Ethics
Stem cell therapy ‘could cut liver transplants’ (Telegraph)
In the campaign to promote taxpayer funding of stem cell research that requires destroying human embryos, political hype often substitutes for the scientific facts.
Embryonic stem cells pose an unusual risk for genetic changes and tumor formation, with the risk increasing the longer the cells are grown, thus making their therapeutic use even more speculative and problematic - Do No Harm
www.stemcellresearch.org   (1185 words)

 HGH Releaser - Human Growth Hormone Releaser
This observation was later linked to the human growth hormone, or HGH, produced and stored by our anterior pituitary gland responsible for human growth and cell reproduction.
Levels of human growth hormone decrease as we age.
Every amount of growth hormone replacement has significant effects - substantially rebuilding and revitalizing all organs of the body.
www.hgh-human-growth-hormone-hgh.us   (533 words)

 Digg - Synthetic Cannabinoid HU210 More Potent than Weed, Helps Brain Cell Growth.
So, if they have developed a phsudo-cannibus then I'll bet you dollars to donoughts that it is patent-pending and will pass with the full support of the same people that decry cannibus legalization.
nyx210, on 10/12/2007, -4/+41More brain cells does not necessarily mean an increase in intelligence...
The brain cell growth was discovered in 2005, and this is all coming from that #1 super reliable news source: wikipedia
digg.com /health/Synthetic_Cannabinoid_HU210_More_Potent_than_Weed_Helps_Brain_Cell_Growth   (3727 words)

 Bacteria Cam
This sequence begins four times daily (your local time) at midnight, 6 AM, noon, and 6 PM.
The length of time between cell divisions is dependent on a number of factors including nutrient concentration, waste concentration, temperature, concentration of gases and more.
Can you tell how long it takes for this population of bacteria to double?
www.cellsalive.com /cam2.htm   (83 words)

 GO:0030308 negative regulation of cell growth
GO:0030308 negative regulation of cell growth - QuickGO
Any process that stops, prevents or reduces the frequency, rate or extent of cell growth.
Note statistics may take upto 1 minute to calculate
www.ebi.ac.uk /ego/DisplayGoTerm?id=GO:0030308   (229 words)

 Cell Growth & Differentiation
Complete Back Issues of Cell Growth & Differentiation
For an alternate route to CG&D Online use this URL:
Copyright © 2008 by the American Association of Cancer Research.
cgd.aacrjournals.org   (28 words)

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