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Topic: Center for Genome Research

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	Oregon National Primate Research Center Plays Key Role in Genome Project
		Researchers at the Oregon National Primate Research Center at Oregon Health & Science University took part in the analysis of the newly completed rhesus macaque monkey genome.
		Rhesus macaques are the most common and preferred monkey species used in biomedical research due to the vast amounts of scientific data that already exist on the monkeys and their many similarities to humans including their immune system, reproductive system, neurobiology, genetics and overall anatomy.
		Of the approximately 4,000 monkeys at the Oregon National Primate Research Center, 3,600 are rhesus macaque monkeys.
	www.ohsu.edu /ohsuedu/newspub/releases/041207rhesusgenome.cfm (744 words)

	Center for Genome Research (Site not responding. Last check: 2007-10-27)
		The MIT Center for Genome Research (formerly the Whitehead Institute / MIT Center for Genome Research, soon to be the MIT Broad Institute) served as the flagship of the Human Genome Project, the international effort to identify the blueprint for a human being.
		Founded in 1990, the Center grew to become one of the largest genome centers in the world and an international leader in the field of genomics, the study of all of the genes in an organism and how they function together in health and disease.
		The Dog Genome Project The Dog Genome Project is a study involving the University of California, Berkeley, the University of Oregon, and the Fred Hutchinson Cancer Research Center.
	www.serebella.com /encyclopedia/article-Center_for_Genome_Research.html (576 words)

	Whitehead Institute Center for Genome Research (Site not responding. Last check: 2007-10-27)
		research center metabolic research center united metabolic research center whitehead nicole whitehead genome human genome genome project human genome project institute boston institute gestalt institute aveda institute
		Whitehead Institute for Biomedical Research The Whitehead Institute is a non-profit, independent basic research and teaching institution recognized worldwide for pathfinding programs in cancer and AIDS research, developmental biology, structural biology, infectious disease, and genetics.
		Genome Sequencing Centre Research department at the Institute of Molecular Biotechnology in Jena, Germany.
	www.serebella.com /encyclopedia/article-Whitehead_Institute_Center_for_Genome_Research.html (416 words)

	Center for Genome Research (Site not responding. Last check: 2007-10-27)
		The MIT Center for Genome Research (formerly the Whitehead Institute / MIT Center for Genome Research soon to be the MIT Broad Institute) served as the flagship the Human Genome Project the international effort to identify the for a human being.
		Founded in 1990 the Center grew to become one the largest genome centers in the world an international leader in the field of genomics the study of all of the genes in an organism and how they together in health and disease.
		Today the Center houses a broad of thriving research programs combining structural genomics medical and population genetics and clinical The Center's annual budget is $80 million it employs 250 people including scientists and researchers from Whitehead MIT and Harvard.
	www.freeglossary.com /Center_for_Genome_Research (148 words)

	ScienceDaily: Scientists Build Case For "Haplotype" Map Of Human Genome, Find New Gene For Crohn's Disease
		In this study, researchers at the Whitehead identified a neighborhood on chromosome 5 wherein lies another gene, IBD5, involved in the disease.
		Researchers believe that in Crohn's patients, faulty responses to microbes that live in the digestive system may somehow trigger the immune system to attack the lining of the digestive tract, causing it to decay and become inflamed.
		Basically, if a researcher is looking at a particular block of the genome, there will frequently be fewer than five flavors of variation of the sequence in that region across entire populations.
	www.sciencedaily.com /releases/2001/10/011004065851.htm (1329 words)

	Profiles
		The Center is the largest public sequencing center in the world and the leading contributor to the international Human Genome Project -having contributed roughly 25% of the sequence of the working draft of the human genome.
		The Washington University Genome Sequencing Center operates under the direction of Robert H. Waterston, M.D., Ph.D., the James S. McDonnell Professor of Genetics and head of the Department of Genetics, and Richard K. Wilson, Ph.D., associate director of the center and research associate professor of genetics.
		The center initially was instrumental in sequencing the genes involved in the major forms of leukemia on human chromosomes 9 and 22, several other cancer-related genes, and then in sequencing a large segment of human chromosome 22, the first completely sequenced human chromosome.
	www.ornl.gov /sci/techresources/Human_Genome/project/feb_pr/profiles.shtml (1936 words)

	Whitehead Institute - Wikipedia, the free encyclopedia
		Founded in 1984, the Whitehead Institute for Biomedical Research is a non-profit research and teaching institution located in Cambridge, Massachusetts.
		The institute is one of the world's leading centers for genomic research.
		Its Center for Genome Research was active in the Human Genome Project, and reportedly contributed one-third of the human genome sequence announced in June 2000.
	en.wikipedia.org /wiki/Whitehead_Institute (165 words)

	Geron - Press Releases
		Dr. Lander's expertise in genomics will be important to Geron as it pursues the genomics of aging, seeking to identify the disease-associated genetic changes that occur between young and old cells.
		Lander is active in several organizations involved in human genetics research, including serving on the board of directors for the Genetic Society of America, and acting as former chair of the Genome Research Review Committee for NIH's National Center for Human Genome Research.
		Specifically, the company's research programs seek to modulate cell senescence to restore normal function in aging cells, and to induce tumor cell death by inhibiting telomerase—an enzyme thought to be responsible for the immortality of cancer cells.
	www.geron.com /pressview.asp?id=616 (380 words)

	NIH Guide: INDIVIDUAL POSTDOCTORAL AND SENIOR FELLOWSHIPS IN GENOMIC ANALYSIS AND TECHNOLOGY AND THE ETHICAL, LEGAL AND ...
		Broad areas of research that are relevant include genomic analysis (including technology development) and the ethical, legal, and social implications of human genetics research.
		RESEARCH OBJECTIVES The mission of the National Center for Human Genome Research (NCHGR) is to characterize the human genome and the genomes of selected model organisms.
		The F33 mechanism is designed to provide research training for scientists or scholars who are at least seven years beyond their doctoral degree and who wish to update their skills or pursue new areas of research.
	grants.nih.gov /grants/guide/pa-files/PA-97-028.html (1315 words)

	Whitehead Institute - Center for Genome Research
		Founded in 1990 by Whitehead Member Eric Lander, the Whitehead/MIT Center for Genome Research grew to become one of the largest genome centers in the world and an international leader in the field of genomics and genetics.
		In addition to sequencing the human genome, the Center played a leadership role in sequencing key model organisms such as the mouse, and other organisms essential for locating regions of the genome that are conserved across multiple species.
		In November of 2003, the Whitehead/MIT Center for Genome Research became the cornerstone facility of the Broad Institute, a new research collaboration between Whitehead Institute, MIT and Harvard University.
	www.wi.mit.edu /about/history/genomecenter.html (397 words)

	NIH Guide: GENOME INFORMATICS PROGRAM
		It is anticipated that the Genome Informatics Program will support informatics research in selected targeted areas and will support establishment and operation of data repositories required to collect the results of the Human Genome Project and to make those results available to the broader biomedical research community.
		RESEARCH OBJECTIVES The primary purposes of Genome Informatics Program are to develop new technology needed to accomplish the objectives of the Human Genome Project and to apply these technologies to the acquisition, management, analysis, and dissemination of mapping and sequencing information.
		It is anticipated that, to the maximum extent possible, research and development projects will be carried out with the active participation of the biological scientists who will be the data generators and users and the ultimate users of the tools and databases developed under this program.
	grants.nih.gov /GRANTS/guide/pa-files/PA-92-059.html (942 words)

	Scientists sequence genome of rice-killing fungus
		According to Dr. Ralph Dean, professor of plant pathology, director of North Carolina State University's Center for Integrated Fungal Research, and principal investigator of the $1.8 million grant that led to the sequencing of rice blast, it is the first time that the genomic structure of a significant plant pathogen has been made publicly available.
		This means that the location of every base, or DNA letter, in the rice blast genome was determined an average of six times, ensuring a relatively high degree of accuracy.
		Dean says NC State researchers are now working to tie the shotgun assembly to the framework, and then annotate, or predict the location of, the genes.
	www.eurekalert.org /pub_releases/2002-07/ncsu-ssg072602.php (563 words)

	Advances in human genome research could widen North-South gap
		The two reports presented simultaneously describe the human genome, or the map of the roughly 30,000 to 35,000 genes of the human species.
		Although Pang agreed it was possible that the mapping of the human genome would lead to the development of increasingly effective medications, he added that the new drugs would in all likelihood be patented and sold at prices that were unaffordable to those in greatest need.
		The sequencing of the human genome poses another danger: that life and health insurance companies will increase the costs of their policies on the basis of an individual’s genetic risk factor.
	www.twnside.org.sg /title/genome.htm (600 words)

	Whitehead Researchers Make Complete Mouse Genome Map (Site not responding. Last check: 2007-10-27)
		The mouse mapping project was made a part of the international genome project because "there are so many striking similarities between the mouse and the human," said Dr. Joyce Miller, project leader of the Whitehead Genome Center.
		It is crucial to map both the mouse and the human genomes because research on human disease often focuses on laboratory mouse models, according to Professor of Biology Eric S. Lander, also director of the Whitehead/MIT Center for Genome Research.
		Use of a mouse model allows researchers "to do a lot of experiments in mice that can't be done in humans, but mice are similar enough to humans that their diseases are similar," Miller said.
	www-tech.mit.edu /V116/N13/whitehead.13n.html (543 words)

	First of crop killer's genome sequence available
		The fungus was recently recognized by the Centers for Disease Control and Prevention as a potentially significant biological weapon that could be used for agricultural terrorism.
		Genome sequencing will allow scientists to understand the interactions between the fungus and grasses, and identify the mechanisms that regulate infection of a host plant.
		The research is continuing at North Carolina State University and the Whitehead Institute's Center for Genome Research in Massachusetts.
	www.eurekalert.org /pub_releases/2002-07/nsf-foc071602.php (293 words)

	CNN.com - Health - Genome announcement 'technological triumph' - June 26, 2000
		Researchers in London announced earlier in the day that they had completed a rough draft of the human blueprint after 10 years of work.
		The Human Genome Project is an international consortium supported mostly by the U.S. National Institutes of Health and the Wellcome Trust, a philanthropic organization based in London.
		Although the public and private groups are using different methods in their human genome projects, they both have as a goal the discovery of the chemicals of the approximately 80,000 genes that make up the human body.
	www.cnn.com /2000/HEALTH/06/26/human.genome.04/index.html (1232 words)

	General Genomic Databases
		The Keck Center for Genome Informatics WWW server at the Institute of Biosciences and Technology, Texas A & M University, is dedicated to providing an interface to genome databases.
		It is operated jointly by the Human Genome Center (HGC), Institute of Medical Science, the University of Tokyo and the Supercomputer Laboratory (SCL), Institute for Chemical Research, Kyoto University, in close cooperation with TISN and WIDE computer network groups in Japan.
		By 'genome information systems' we mean the sorts of computer systems constructed at genome centers, as well as organism-specific data resources and other public data repositories.
	biotech.icmb.utexas.edu /pages/science/general.html (491 words)

	Broad Institute - Wikipedia, the free encyclopedia
		The Broad Institute of MIT and Harvard, formerly the Whitehead Institute/MIT Center for Genome Research (WICGR), is a multidisciplinary institution dedicated to fulfilling the potential of genome research for the biomedical sciences.
		The Broad Institute's facilities at 320 Charles Street in Cambridge, MA, house one of the largest genome sequencing centers in the world.
		As WICGR, this facility was the largest contributor of sequence information to the Human Genome Project.
	en.wikipedia.org /wiki/Center_for_Genome_Research (180 words)

	Manolis Kellis - Research Interests
		The first step to comparative genomics is to determine what regions to compare across the multiple species analyzed.
		The work led to the largest re-annotation of the genome since its original sequencing, reducing the overall gene count by 10%, and proposing changes that affect nearly 15% of all genes.
		For Minsky's class, I did some research on evolution and the human DNA and wrote a paper on how along with the genetic data, meta-information can be propagated to direct the interpretation of the raw data.
	www.mit.edu /people/manoli/research.html (2911 words)

	Wired News: Beyond MP3s: IPod Holds Genome
		Will Gilbert, head of the bioinformatics group in the Hubbard Center for Genome Studies at the University of New Hampshire has found that the iPod is a perfect way to store the gene sequence -- and it's faster than waiting for his network to churn out the data.
		Researchers at UC Santa Cruz had created a genome map that delineated 192 regions in the genome they believed contained such genes.
		Researchers are still deciphering which of the eight different versions of BLAST and BLAST-like technologies is best for which jobs.
	www.wired.com /news/medtech/0,1286,56223,00.html (1003 words)

	Center for Medicago Genomics Research
		Exploitation of the diverse and complex chemistry of legumes for the benefit of humankind requires in-depth knowledge of the legume genome.
		A Center for Medicago Genomics Research was established at The Samuel Roberts Noble Foundation in the fall of 1999.
		The program's bioinformatics needs are currently being met through partnerships with the National Center for Genome Resources (NCGR) and the Virginia Bioinformatics Institute (VBI).
	www.noble.org /medicago (616 words)

	- WSAVA - Canine Genome selected for Research - AKC
		New York, NY — The National Human Genome Research Institute (NHGRI) recently announced the addition of the cow and the dog to the list of high priority organisms that should be considered for genome sequencing.
		Scientists were asked to submit proposals stating their case as to why the genome they were interested in deserved high priority status.
		A proposal to sequence the dog genome was submitted by scientists from the Fred Hutchinson Cancer Research Center (Seattle, WA), the Whitehead/MIT Center for Genome Research (Cambridge, MA), and the Canine Genome Mapping Community (composed of researchers from the U.S. and several other countries).
	www.wsava.org /CanineGenome.html (404 words)

	UC Davis Genome Center
		The UC Davis Genome Center integrates experimental and computational approaches to address key problems at the forefront of genomics.
		The Center is housed in a new research building with state-of-the-art computational and laboratory facilities and currently comprises 16 experimental and computation faculty.
		Candidates should be strongly motivated by the biological importance of their research and should value the opportunity to work in close collaboration with other groups.
	genomics.ucdavis.edu (806 words)

	Fungal Genome Initiative - Broad
		The FGI is a partnership between the Broad Institute and the wider fungal research community, with the selection of target genomes being governed by a steering committee of fungal scientists.
		By comparing sequence from one genome to another and correlating genomic differences with phenotypic differences, such as pathogenicity or production of drugs, scientists may be able to narrow the search for genes and regions that underlie important behaviors.
		The FGI has been supported by the National Human Genome Research Institute, the National Science Foundation, the National Institute of Allergy and Infectious Disease, and the US Department of Agriculture.
	www.broad.mit.edu /annotation/fungi/fgi (225 words)

	Human Genome Project (Site not responding. Last check: 2007-10-27)
		The Human Genome Project, the international effort to decipher the blueprint of a human being.
		The Whitehead Institute's Center for Genome Research is an international leader in the Human Genome Project (the effort to identify all of the DNA letters that make up the instructions for a human being).
		The Center is the largest public sequencing center in the world and part of the international consortium of 16 laboratories that comprise the Human Genome Project.
	www.samogden.com /Human_Genome_Project.html (173 words)

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