Factbites
 Where results make sense
About us   |   Why use us?   |   Reviews   |   PR   |   Contact us  

Topic: Centimorgan


In the News (Fri 11 Dec 09)

  
  Centimorgan - Wikipedia, the free encyclopedia
In genetics, a centimorgan (abbreviated cM) is a unit of recombinant frequency.
The centimorgan is equal to a 1% chance that a marker at one genetic locus on a chromosome will be separated from a marker at a second locus due to crossing over in a single generation.
In human beings, one centimorgan is equivalent, on average, to one million base pairs.
en.wikipedia.org /wiki/Centimorgan   (128 words)

  
 MOUSE CHROMOSOME ATLAS
This genetic map of the mouse shows the location of loci in terms of recombinational distance from the centromere, the correlation between the genetic and cytogenetic maps, and the known homologies to human chromosomes.
Between centimorgan distances the order of loci is the best estimate derived from consideration of the literature, particularly Copeland et al ( 1993), and again should be considered approximate.
Within a centimorgan position no attempt has been made to show the order of the loci, and loci are listed alphabetically.
www2.bioch.ox.ac.uk /~jhe/wpdf/MlyonAtlas.html   (693 words)

  
 Centimorgan (cm) - Talk Medical
Centimorgan (cM): A unit of measure of genetic recombination frequency.
One cM is equal to a 1% chance that a marker at one genetic locus will be separated from a marker at another locus due to crossing over in a single generation.
The centimorgan is named after the pioneering (and Nobel Prize winning) geneticist Thomas Hunt Morgan.
www.talkmedical.com /medical-dictionary/2670/Centimorgan-cm-   (101 words)

  
 centimorgan
The morgan is not used, only the centimorgan.
The genetic distance between two loci is 1 cM if their statistically corrected recombination frequency is 1%; the genetic distance in centimorgans is numerically equal to the recombination frequency expressed as a percentage.
The centimorgan is named for Thomas Hunt Morgan ( 1866–1945), who won a Nobel Prize for his work on the genetics of fruit flies.
www.sizes.com /units/centimorgan.htm   (102 words)

  
 Patterns of Chromosomal Duplication in Maize and Their Implications for Comparative Maps of the Grasses -- Gaut 11 (1): ...
deviate between 0.0 and the centimorgan length of the tester chromosome.
The centimorgan map locations and P values of runs based on the ss metric and a 2.0-cM error allowance are given (Table 1).
The standard chromosome is shown in light blue, with the centromere in royal blue; the vertical axis represents the centimorgan location on the standard chromosome.
www.genome.org /cgi/content/full/11/1/55   (5985 words)

  
 Linkage and Linkage Maps
Centimorgans are calculated from observed % recombination, and attempt to take into account double crossovers.
The centimorgan is thus a statistical unit of measure without a physical basis (i.e.
This is readily apparent in organisms with large genomes, where the ratio of cM to base pairs can vary enormously across the genome.
cropandsoil.oregonstate.edu /classes/css43003/notes6.htm   (1465 words)

  
 ARS | Publication request: Identification of Quantitative Trait Loci for Growth and Carcass Composition in Cattle   (Site not responding. Last check: 2007-11-04)
Quantitative trait loci were classified as significant when the expected number of false positives (ENFP) was less than.05 (F-statistic greater than 17.3), and suggestive when the ENFP was less than 1 (F-statistic between 10.2 and 17.29).
A significant quantitative trait loci (F = 19; ENFP =.02) was detected for marbling score at centimorgan 54 on chromosome 2.
Two suggestive quantitative trait loci for birth weight were identified, one at centimorgan 12 on chromosome 20 and the other at centimorgan 56 on chromosome 21.
www.ars.usda.gov /research/publications/publications.htm?seq_no_115=150357&pf=1   (413 words)

  
 APPENDIX E: Glossary of Terms
A centimorgan is the distance between two genes that will recombine with a frequency of exactly one percent.
Interference is responsible for a severe reduction in the expected frequency of double crossover events in ten to twenty centimorgan lengths of the genome (see Chapter 7).
A cross between mice from two different species, most often M. musculus (represented by a traditional laboratory strain) and M. spretus for the purpose of linkage analysis.
www.informatics.jax.org /silver/glossary.shtml   (3526 words)

  
 Jumping Librairy
Both of which are placed at less than 0.5 centimorgan from the CF gene by current linkage estimates.
A CentiMorgan (cM) is a unit used to express distances on a genetic map.
In genetic mapping, distances between markers are determined by measuring the rate of meoitic recombination between them, which increases proportionately with the distance separating them.
www.icampus.ucl.ac.be /SBIM2520/document/genemol/electrophorese/jumpinglibrairies.html   (901 words)

  
 HGP Five-Year Plan: Scientific Goals   (Site not responding. Last check: 2007-11-04)
The physical or molecular distance to which a centimorgan corresponds varies a great deal, but the genome-wide average distance for a centimorgan is believed to be roughly 1 million base pairs.
It is estimated that 3000 well-spaced and informative markers will be needed to achieve a completely linked map, with markers an average of one centimorgan apart as recommended by the NRC.
For the first five years, the genome program has set as its goal the creation of a 2 to 5 centimorgan map, which would require 600 to 1500 such markers.
genome.rtc.riken.go.jp /hgmis/project/5yrplan/science.html   (2858 words)

  
 A one centimorgan deletion unit on chromosome Xq12 is commonly lost in borderline and invasive epithelial ovarian tumors
A one centimorgan deletion unit on chromosome Xq12 is commonly lost in borderline and invasive epithelial ovarian tumors
X chromosome activation studies performed in cases with LOH at the AR locus showed that the allelic loss at the AR locus is not confined to the inactive allele.
A one centimorgan region including the AR locus and flanked by the primers DXS1161 and PGK1P1 was identified as the smallest common loss region in both borderline and invasive epithelial ovarian tumors.
www.nature.com /cgi-taf/DynaPage.taf?file=/onc/journal/v16/n2/abs/1201479a.html   (308 words)

  
 centimorgan - BioInformatics Glossary   (Site not responding. Last check: 2007-11-04)
Two markers are said to be 1 cM apart if they are separated by recombination 1% of the time.
In humans, one centimorgan is equivalent, on average, to one million base pairs.
The process by which progeny derive a combination of genes different from that of either parent.
big.mcw.edu /display.php?cM   (58 words)

  
 [No title]
It was then discontinued because knowledge, particularly of microsatellite markers, had become so detailed as to make the map impractical.
Between centimorgan distances the order of loci is the best estimate derived from consideration of the literature, particularly Copeland {\i et al (}1993), and again should be considered approximate.
Within a centimorgan position no attemp t has been made to show the order of the loci, and loci are listed alphabetically.
www2.bioch.ox.ac.uk /~jhe/wpdf/MlyonAtlas.rtf   (581 words)

  
 [No title]
In particular, the use by industry of recombinant DNA, cell fusion, and new bioprocessing techniques.
Centimorgan (cM): A unit of measure of recombination frequency.
Centromere: A specialized chromosome region to which spindle fibers attach during cell division.
www.cs.columbia.edu /digigov/LEXING/Bio_LBNL/gloss.html   (3843 words)

  
 [Biojava-l] Locations in centiMorgans   (Site not responding. Last check: 2007-11-04)
I do however need their location in centiMorgans.
Currently I am fetching for every gene two known nearby centiMorgan locations (using NCBI's genome viewer) and interpolate to derive the centiMorgan location for every SNP inside the gene, using a small script I wrote.
This method is a bit time consuming and needs to be automated in the near future.
www.biojava.org /pipermail/biojava-l/2004-May/004553.html   (199 words)

  
 Gibson Publication   (Site not responding. Last check: 2007-11-04)
A moderate resolution single nucleotide polymorphism (SNP) map of the genome of Drosophila melanogaster that is designed for use in quantitative genetic mapping is described.
Seventeen approximately 500 nucleotide gene sequences spaced at 10 to 20 centimorgan intervals were combined with 49 shorter sequence tag sites (STSs) at 5 to 10 centimorgan intervals to generate a map that should not leave any gaps greater than one half of a chromosome arm when any two wild type lines are compared.
Of 20 markers with sufficient polymorphism to construct haplotype cladograms, 13 showed evidence for two divergent classes of haplotype.
www.cals.ncsu.edu /genetics/gibson/gg3.html   (169 words)

  
 [No title]   (Site not responding. Last check: 2007-11-04)
Cell fusion: The joining of the membrane of two cells, thus creating a single hybrid cell that contains nuclear matter from both the parent cells.
Centimorgan: A unit of measure of genetic recombination frequency.
One centimorgan is equal to a 1 percent chance that a genetic locus will be separated from a marker due to recombination in a single generation.
www.biol.tsukuba.ac.jp /~macer/SG18.html   (7013 words)

  
 Consequences of Recombination Rate Variation on Quantitative Trait Locus Mapping Studies: Simulations Based on the ...
in gene density per centimorgan across this genome, and we observe
of multiple QTL in regions of high gene density per centimorgan.
per centimorgan in the centromeric regions of the two autosomes.
www.genetics.org /cgi/content/full/159/2/581   (4218 words)

  
 BIOL2316 Genetics
What is the maximum mapping distance in centimorgans for two genes?
Draw a Punnett Square of a cross between a female homozygous for an X-linked mutation, homozygous for a Y-linked gene and a male with the wild-type X-linked gene and mutant in the Y-linked gene.
Now that we have sequenced genomes, we can compare the genetic mapping distance with the actual distance between genes.
www.austin.cc.tx.us /pphelps/BIOL2316.notes.Ch5.05a.htm   (438 words)

  
 A Scan for Linkage Disequilibrium Across the Human Genome -- Huttley et al. 152 (4): 1711 -- Genetics
Figure 4 as a function of recombination distance (centimorgans).
(d) Centimorgan distance between STRP markers and average LDp values between markers within each centimorgan interval.
of inverse centimorgans to the likelihood of LD.
www.genetics.org /cgi/content/full/152/4/1711   (6133 words)

  
 Positional cloning
1) Close mapping of the target gene so that markers are determined less than a centimorgan from the gene.
This can often be obtained using many AFLP markers and large mapping populations.
One centiMorgan in most plant species still means more than a megabase (1 million bp) of DNA sequence.
www.agsci.kvl.dk /breed/kortleg1/Background/Markertypes/positional_cloning.htm   (455 words)

  
 AllelNumbers   (Site not responding. Last check: 2007-11-04)
Specify a marker locus by name and position.
Specify a marker locus by name and position (in centimorgan).
The position in centimorgan as distance from 0.0.
www.imbs.mu-luebeck.de /pub/sibsim/doc/ref-allelnumbers.html   (26 words)

  
 Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations
Energy Citations Database (ECD) Document #6523984 - A comprehensive human linkage map with centimorgan density
Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link.
A comprehensive human linkage map with centimorgan density
www.osti.gov /energycitations/product.biblio.jsp?osti_id=6523984   (130 words)

  
 [No title]   (Site not responding. Last check: 2007-11-04)
From bio.indiana.edu!usenet.ucs.indiana.edu!sol.ctr.columbia.edu!zaphod.mps.ohio-state.edu!saimiri.primate.wisc.edu!ames!agate!pathos!nigel Tue Nov 3 17:48:13 1992 From: nigel@pathos (Nigel Walker) Newsgroups: bionet.molbio.gene-linkage,bionet.plants,bionet.molbio.evolution,bionet.genome.arabidopsis Subject: What _is_ a Kosambi centimorgan?
Keywords: Centimorgan, Kosambi, genetics, Helentaris Hi, I was just wading through this months Genetics and ran into a term I can't figure out.
As the subject line says: What is a Kosambi centimorgan?
iubio.bio.indiana.edu:70 /R22094-23547-/Network-News/bionet/plants/9211.newsm   (99 words)

  
 Linkage and Linkage Maps
The centiMorgan is a unit of distance without a physical basis.
coupling/repulsion, coefficient of coincidence, crossing over, interference, linkage, linkage group, linkage map, parental/recombinant, recombination %, centimorgan, three-point, testcross.
An example of linkage map construction and utility in the OWBs:
cropandsoil.oregonstate.edu /classes/css430/notes6.htm   (1435 words)

  
 Glossary
An intermolecular bond is called a hydrogen bond.
CENTIMORGAN (cM) - A unit of measure of recombination frequency.
COMPLEMENTARY DNA (cDNA) - DNA that is made from a mRNA.
home.san.rr.com /dna/darryl/glossary.html   (2487 words)

  
 Vertebrate Comparative Database   (Site not responding. Last check: 2007-11-04)
If you do select overlapping ranges, then loci whose localisation partially, but not completely overlaps your range of segments will also be found.
Enter the chromosome number (or X or Y) in the map location field.
In the centiMorgan range field, enter the lower and upper range of centiMorgan positions you want to search on, separated by a space.
www.hgmp.mrc.ac.uk /Comparative/Comparative_Help.html   (452 words)

  
 Extensive Genome-wide Linkage Disequilibrium in Cattle -- Farnir et al. 10 (2): 220 -- Genome Research
The first data set used to measure LD in the dutch fl-and-white population was a previously described granddaughter design
( A) Distribution of D ' values observed between syntenic marker pairs as a function of genetic distance in centimorgan (cM).
The red lines correspond to average D ' values for marker pairs sorted in 5 cM bins (0-50 cM) or 10-cM bins (50-190 cM).
www.genome.org /cgi/content/full/10/2/220   (4585 words)

  
 Centimorgan (cM) - Medical Dictionary definitions of popular medical terms
Centimorgan (cM) - Medical Dictionary definitions of popular medical terms
MedicineNet Home > MedTerms medical dictionary A-Z List > Centimorgan (cM)
Please consult your healthcare provider before beginning any course of supplementation or treatment.
www.medterms.com /script/main/art.asp?articlekey=2665   (269 words)

Try your search on: Qwika (all wikis)

Factbites
  About us   |   Why use us?   |   Reviews   |   Press   |   Contact us  
Copyright © 2005-2007 www.factbites.com Usage implies agreement with terms.