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Topic: Central pontine myelinolysis

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	Central pontine myelinolysis
		Central pontine myelinolysis is a neurologic disease caused by severe damage of the myelin sheath of nerve cells in the brainstem, more precisely in the area termed the pons.
		Central pontine myelinolysis: a hitherto undescribed disease occurring in alcoholics and malnourished patients.
		Central pontine and extrapontine myelinolysis: a report of 58 cases.
	www.mrsci.com /Neurology/Central_pontine_myelinolysis.php (171 words)

	Central pontine myelinolysis was first described by Adams et al... (Site not responding. Last check: 2007-11-03)
		Central pontine myelinolysis was first described by Adams et al in 1959 during the course of studying the neuropathology of alcoholism.
		CPM was usually a postmortem diagnosis till the advent of the CT and the MRI.
		Chronicity of hyponatremia as a factoir in experimental myelinolysis.
	www.indegene.com /Neu/ClinRound/indNeuCase10.html (1219 words)

	Central pontine myelinolysis associated with hypokalaemia in anorexia nervosa -- Sugimoto et al. 74 (3): 353 -- Journal ...
		Central pontine myelinolysis (CPM) is a demyelinative lesion
		Neuropsychiatric and neuropsychological manifestations of central pontine myelinolysis.
		Central pontine myelinolysis secondary to frequent and rapid shifts in plasma glucose in a diabetic haemodialysis patient.
	jnnp.bmj.com /cgi/content/full/74/3/353 (1434 words)

	Central pontine myelinolysis - Evanston Northwestern Healthcare (Site not responding. Last check: 2007-11-03)
		The most common cause of central pontine myelinolysis is a rapid, drastic change in sodium levels in the body.
		There is no known cure for central pontine myelinolysis and treatment is focused on relieving symptoms.
		The nerve damage caused by central pontine myelinolysis is usually long-lasting.
	www.enh.org /healthandwellness/encyclopedia/ency/article/000775.aspx (503 words)

	Central Pontine Myelinolysis Information Page: National Institute of Neurological Disorders and Stroke (NINDS)
		Central pontine myelinolysis (CPM) is a neurological disorder that most frequently occurs after too rapid medical correction of sodium deficiency (hyponatremia).
		The initial symptoms of myelinolysis, which begin to appear 2 to 3 days after hyponatremia is corrected, include a depressed level of awareness, difficulty speaking (dysarthria or mutism), and difficulty swallowing (dysphagia).
		At its most severe, myelinolysis can lead to coma, “locked-in” syndrome (which is the complete paralysis of all of the voluntary muscles in the body except for those that control the eyes), and death.
	www.ninds.nih.gov /disorders/central_pontine_myelinolysis.htm (684 words)

	Central pontine myelinolysis
		CPM is a degeneration of a symmetrical midline patch of the basis pontis.
		Extension to the cerebral hemispheres and the cerebellum (extrapontine myelinolysis) is seen in some cases.
		CPM was initially reported in alcoholic patients and was thought to be a complication of alcoholism.
	www.neuropathologyweb.org /chapter6/chapter6dCPM.html (245 words)

	JPMA ::: (Site not responding. Last check: 2007-11-03)
		We have reviewed the published cases of extra pontine myelinolysis and believe this to be the first report of EPM occurring in the setting of severe hypophosphatemia.
		Central pontine myelinolysis (CPM) and extra-pontine myelinolysis (EPM) is a distinct clinical syndrome and is characteristically found in malnourished alcoholics with chronic hyponatremia which is corrected too rapidly.
		Central and extrapontine myelinolysis in a patient in spite of a careful correction of hyponatremia.
	jpma.org.pk /jpma/6june05/fulltex11.htm (1151 words)

	Central pontine myelinolysis
		Alcoholism, Wernicke-Korsakoff syndrome, and general ill health and malnutrition associated with serious illnesses (cachexia) increase the risk of central pontine myelinolysis.
		Prognosis: The neurologic damage caused by central pontine myelinolysis is usually persistent.
		Go to the emergency room or call the local emergency number (such as 911) if seizures, muscle weakness, or other symptoms of central pontine myelinolysis occur.
	www.rwjobgyn.com /Atoz/Encyclopedia/article/000775.asp (430 words)

	Parkinsonism and dystonia in central pontine and extrapontine myelinolysis -- Seiser et al. 65 (1): 119 -- Journal of ...
		Parkinsonism and dystonia in central pontine and extrapontine myelinolysis -- Seiser et al.
		Parkinsonism and dystonia in central pontine and extrapontine myelinolysis
		Pontine myelinolysis presenting with acute parkinsonism as a sequel of corrected hyponatriemia.
	jnnp.bmjjournals.com /cgi/content/full/65/1/119 (884 words)

	Early Diagnosis of Central Pontine Myelinolysis with Diffusion-Weighted Imaging -- Ruzek et al. 25 (2): 210 -- American ...
		Central pontine myelinolysis (CPM) is an osmolar disturbance
		Cramer SC, Stegbauer KC, Schneider A. Decreased diffusion in central pontine myelinolysis.
		Osmotic demyelination disorders: central pontine and extrapontine myelinolysis.
	www.ajnr.org /cgi/content/full/25/2/210 (1674 words)

	Central pontine myelinolysis
		Central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of the covering layer (myelin sheath) of nerve cells in the brainstem (pons).
		The destruction of the myelin sheath that coats nerves inhibits impulse conduction within the cell and thus decreases its ability to communicate with other cells.
		Most commonly, this occurs when someone is being treated for low levels of sodium (hyponatremia) and the levels rise too fast, but it can occasionally occur when high levels of sodium in the body (hypernatremia) are corrected too quickly.
	www.stlukes-stl.com /ency/article/000775.htm (255 words)

	Myelinolysis after Correction of Hyponatremia -- Laureno and Karp 126 (1): 57 -- Annals of Internal Medicine
		the syndrome of myelinolysis from the symptoms of hyponatremia.
		a symmetrical central pontine lesion of characteristic histology.
		Central pontine myelinolysis: CT and BAER correlates of acute and recovery phases [Abstract].
	www.annals.org /cgi/content/full/126/1/57 (3797 words)

	eMedicine - Central Pontine Myelinolysis : Article Excerpt by: Christopher C Luzzio, MD (Site not responding. Last check: 2007-11-03)
		During the period of hyponatremia, the concentration of intracellular charged protein moieties is altered; reversal cannot parallel a rapid correction of electrolyte status.
		The term "osmotic myelinolysis" is more appropriate than "central pontine myelinolysis" for demyelination occurring in extrapontine regions after the correction of hyponatremia.
		A study by Singh et al demonstrated that CPM was present in 29% of postmortem exams of liver transplant patients.
	www.emedicine.com /neuro/byname/central-pontine-myelinolysis.htm (349 words)

	Central pontine and extrapontine myelinolysis: the osmotic demyelination syndromes -- Martin 75 (Supplement 3): iii22 ...
		Figure 2 Relative proportions of central pontine myelinolysis (CPM), extrapontine myelinolysis (EPM), and CPM with EPM.
		CPM is a recognised complication of liver transplantation.
		Evidence for a role for apoptosis in central pontine myelinolysis.
	jnnp.bmj.com /cgi/content/full/75/suppl_3/iii22 (3578 words)

	Central Pontine Myelinolysis (Site not responding. Last check: 2007-11-03)
		He sent for his appearance before the grave manifestation of the history of the operations of central pontine myelinolysis prison yard, with washstand, bureau, and I have gathered.
		unsatisfactory effect on the general progress or decline in a central pontine myelinolysis large man--apoplectic and with sclerotic veins and arteries.
		You're a great improvement in taste over that which is central pontine myelinolysis out of her great passion for him.
	www.jvlo.com /162/central-pontine-myelinolysis.html (397 words)

	Virginia Hospital Center - Central Pontine Myelinolysis
		This is an emergency disorder that requires hospitalization for initial diagnosis and treatment.
		The neurologic damage caused by central pontine myelinolysis is usually persistent.
		Gradual controlled correction of hyponatremia or hypernatremia may reduce the risk of damage to the nerves of the pons.
	www.virginiahospitalcenter.com /content/adam_000775.asp (479 words)

	Medical Dictionary: Central pontine myelinolysis - WrongDiagnosis.com
		Central pontine myelinolysis is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
		This means that Central pontine myelinolysis, or a subtype of Central pontine myelinolysis, affects less than 200,000 people in the US population.
		Terms that may be interchangeable with Central pontine myelinolysis:
	www.wrongdiagnosis.com /medical/central_pontine_myelinolysis.htm (221 words)

	Central Pontine Myelinolysis
		The second neurologist said the MRI indicated central & extra-pontine, with damages shown to the pons and also Basal Ganglia.
		She was confirmed CPM, due apparently to the too rapid correction of sodium chloride during the first 35 hours (to 128) following the coma & seizure after Hyponatremia.
		Nor is there any authority to rule out the process or point to the timing of a brain damage like CPM or other brain disorders.
	www.medhelp.org /forums/neuro/messages/30819a.html (972 words)

	Amazon.com: "central pontine myelinolysis": Key Phrase page (Site not responding. Last check: 2007-11-03)
		, methotrexate), PML Pontine trident-shaped lesion Central pontine myelinolysis Thalamus, occipital, pontine lesion Acute basilar artery occlusion Temporal, frontal lobe Herpes simplex encephalitis hyperintensities Parietal-occipital lesions Cyclosporine, tacrolimus neurotoxicity,...
		Central Pontine Mvelinolvsis Central pontine myelinolysis (CPM) is a rarely occurring demyelination syndrome that is characterized by symmetric pontine lesions.
		Experimental studies have suggested that excessively rapid correction of hyponatremia may be responsible for this lesion, as well as central pontine myelinolysis (Kleinschmidt-DeMas- ters and Norenberg, 1981).
	www.amazon.com /phrase/central-pontine-myelinolysis (534 words)

	Help HER - » For Health Professionals \| Complications \| Central Pontine Myelinolysis (Site not responding. Last check: 2007-11-03)
		Nerve damage caused by the destruction of the covering layer (myelin sheath) of nerve cells in the brainstem (pons).
		Magnetic resonance imaging detection of a lesion compatible with central pontine myelinolysis in a pregnant patient with recurrent vomiting and confusion.
		[Central pontine myelinolysis and pregnancy: a case report and review of literature] [Article in Spanish]
	www.helpher.org /health-professionals/complications/central-pontine.php (161 words)

	Resource Library: Find information on Central pontine myelinolysis at MerckSource (Site not responding. Last check: 2007-11-03)
		Resource Library: Find information on Central pontine myelinolysis at MerckSource
		The manufacture of a product generally has the most complete information about that product.
		Please discuss any and all treatment options for your condition with your healthcare professional.
	www.mercksource.com /ppdocs/us/cns/content/adam/ency/article/000775.htm (496 words)

	Dr. Koop - Central pontine myelinolysis
		Home > Health Reference > Central pontine myelinolysis
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	www.drkoop.com /ency/93/000775.html (384 words)

	Medical Dictionary: Osmotic myelinolysis - WrongDiagnosis.com
		Osmotic myelinolysis: A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness.
		Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons.
		Terms that may be interchangeable with Osmotic myelinolysis:
	www.wrongdiagnosis.com /medical/osmotic_myelinolysis.htm (261 words)

	central pontine myelinolysis - available resources from Patient UK
		central pontine myelinolysis - available resources from Patient UK central pontine myelinolysis
		central pontine myelinolysis - also known as or related to myelinolysis--central pontine or extra-pontine, osmotic demyelination syndrome, central pontine myelinosis, central pontine myelinolysis (disorder)
		Use the Google Search box below to search our site (default) or to search on the internet.
	www.patient.co.uk /leaflets/central_pontine_myelinolysis.htm (165 words)

	ENLmedical.com: Conditions And Concerns: Medical Encyclopedia: Central pontine myelinolysis
		ENLmedical.com: Conditions And Concerns: Medical Encyclopedia: Central pontine myelinolysis
		The most common cause of this condition is rapid correction of low sodium levels in the body (hyponatremia).
		Although not usually a direct threat to life, the disorder can cause serious chronic disability.
	www.enlmedical.com /article/000775.htm (305 words)

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	www.phil-taylor.com /directory/Central_Pontine_Myelinolysis_?c4065 (35 words)

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