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| | Biophysical Journal: Effects of epicholesterol on the phosphatidylcholine bilayer: A molecular simulation study (Site not responding. Last check: 2007-10-09) |
 | | Cholesterol (Chol, [beta]-OH-Chol) is an important constituent of the animal cell membrane, where it accounts for up to 50 mol % of the membrane lipids (e.g., Sackmann, 1995). |
 | | In Chol, the hydroxyl group is in the [beta]-conformation (is located on the [beta]-face), whereas in Echol, the hydroxyl group, is in the [alpha]-conformation (is located on the [alpha]-face). |
 | | Chol in concentration 30 mol % eliminates the main phase transition, whereas Echol does not (De Kruyff et al., 1972). |
| www.findarticles.com /p/articles/mi_qa3938/is_200303/ai_n9193962 (1296 words) |
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