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Topic: Chemical biology


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In the News (Sat 26 Dec 09)

  
  Chemical biology - Wikipedia, the free encyclopedia
Chemical biology is a scientific discipline spanning the fields of chemistry and biology that sometimes employs compounds produced by synthetic chemistry to study and manipulate biological systems.
Chemical biology is one of many interfacial sciences which are symptiomatic of a general trend in the early 21st century away from older, reductionist fields toward those whose goals are to achieve a description of scientific holism.
Chemical biology is attempting to answer many questions about the function, structure, affinity and location of all the proteins within a living cell.
en.wikipedia.org /wiki/Chemical_biology   (909 words)

  
 Chemistry and Chemical Biology   (Site not responding. Last check: 2007-11-05)
The Department of Chemistry and Chemical Biology offers a program of study leading to the degree of doctor of philosophy in chemistry, in the special fields of biological, inorganic, organic, and physical chemistry.
Chemical reactivity of radical-radical and radical-molecule systems; chemical catalysis sustained by free radical chain reactions in the Earth's stratosphere and troposphere; mechanistic links between chemistry, radiation, and dynamics in the atmosphere that control climate; high-accuracy satellite observations for testing and systematic improvement of climate forecasts.
Organic chemistry and chemical biology of molecular evolution, nucleic acid-templated organic synthesis, reaction discovery, protein and nucleic acid evolution and engineering, synthetic polymer evolution; generally, effective molarity-based approaches to controlling reactivity and evolution-based approaches to the discovery of functional synthetic and biological molecules.
www.gsas.harvard.edu /programs/degree/chem.html   (2603 words)

  
 Chemical Biology   (Site not responding. Last check: 2007-11-05)
The goal of the Chemical Biology Program is biological discovery, and its approach is the seamless integration of principles and experimental techniques drawn from both chemistry and biology.
The focus of chemical biology is on biology, which distinguishes it from traditional chemistry, and it uses chemical tools, which distinguishes it from traditional biology.
The objective of the Chemical Biology Program is to prepare investigators with diverse background for independent research careers in which the concepts and methods of chemistry are applied to biological problems.
www.gsas.harvard.edu /programs/degree/chembio.html   (1347 words)

  
 An Overview of Graduate Studies in Chemical Biology   (Site not responding. Last check: 2007-11-05)
Chemists are addressing problems in biochemistry, pharmacology, cell biology, structural biology, and medicine by designing and constructing small molecules as spectroscopic probes, functional congeners, and diagnostic and therapeutic agents.
The methods of molecular biology, biomimetics and genetics, in turn, are providing approaches and solutions to chemical problems, through mutagenesis to probe the mechanisms of enzymatic reactions, through the production of large quantities of pure proteins for spectroscopic and biophysical studies, and by the convenient generation of structural diversity.
The Graduate Studies in Chemical Biology is an area within the Department of Chemistry and is open to any graduate student in the department.
www.scs.uiuc.edu /chem/gradprogram/cb-overview.html   (669 words)

  
 WIKI
Chemical biology is a discipline at the interface of the life sciences and the physical sciences.
Everyone has their own definition of what it mean to be a chemical biologists, the tools that chemical biologists use in their research, and how one trains to work in this research area.
We know that there are many new programs in chemical biology that are emerging all over the world.
community.acs.org /journals/acbcct/cs/WIKI/tabid/54/Default.aspx   (504 words)

  
 Broad Institute - Chemical Biology Program
He is a Founder and Director of the Harvard ICCB and its affiliated and NCI-sponsored Initiative for Chemical Genetics, and a member of the faculty of the Broad Institute (a joint initiative of Harvard University and MIT).
Dr. Schreiber is known for having developed systematic ways to explore biology, especially disease biology, using small molecules (precursors to therapeutic drugs that are used as bioprobes) and for his role in the development of the field of chemical biology.
Chemical biology and cell circuitry: Systematic study of biology using small molecules; development and application of diversity-oriented organic synthesis and ChemBank.
www.broad.mit.edu /chembio/lab_schreiber/members/schreiber.html   (1451 words)

  
 U.S. Newswire : Releases : "ACS Chemical Biology the New Interface..."   (Site not responding. Last check: 2007-11-05)
The launch of ACS Chemical Biology comes at a time when funding agencies and companies are investing heavily in this emerging field, in part, because it promises to revolutionize the way chemists and biologists study cells and manage disease.
As researchers in chemical biology ourselves, the board of editors and I are committed to leveraging ACS Chemical Biology in every way we can to meet the needs of young and established members of our research community and disseminate important findings as broadly as possible to advance the field."
The American Chemical Society - the world's largest scientific society - is a nonprofit organization chartered by the U.S. Congress and a global leader in providing access to chemistry- related research through its multiple databases, peer-reviewed journals and scientific conferences.
releases.usnewswire.com /GetRelease.asp?id=59699   (565 words)

  
 Broad Institute - Chemical Biology Program
He is a Founder and Director of ICCB and its affiliated and NCI-sponsored Initiative for Chemical Genetics, (ICG) and a member of the faculty of the Broad Institute (a joint initiative of Harvard University and MIT).
Using chemical genetic epistasis analysis, diversity-oriented synthesis, small molecule microarrays, among others, the nutrient-response signaling network involving TOR proteins in yeast and mammalian cells has been illuminated.
The hope is to gain an understanding of the relationship of chemical and biological spaces and thereby to diminish the gap between biology and medicine in the future.
www.broad.harvard.edu /chembio/lab_schreiber/sciOver   (1900 words)

  
 About CMS—Chemical Biology and Nuclear Science Division   (Site not responding. Last check: 2007-11-05)
The Chemical Biology and Nuclear Science Division (CBND) is positioned at the intersection of chemical, biological, and nuclear science and provides unique and combined solutions to issues related to national security and nonproliferation and arms control programs.
Our Chemical Environmental Services (CES) laboratory is a State of California-certified environmental laboratory that provides high-volume analysis of Laboratory waste and process streams; it has expanded its client base to include nonstandard sample analyses required for the decommissioning and dismantlement of surplus buildings and radiochemical facilities at the Laboratory site.
As the Chemical Biology and Nuclear Science Division continues to grow and position its many capabilities at the intersection of nuclear, chemical, and biological science important to all the major programs, it continues to make significant contributions to the success of primary missions throughout the directorate and the Laboratory
www-cms.llnl.gov /about/cbnd.html   (921 words)

  
 Stevens Institute | Chemistry & Chemical Biology   (Site not responding. Last check: 2007-11-05)
An absorbance peak in IR region might be exactly attributed to the chemical bond responsible for the extinction of light at a given wavelength.
High pressure liquid chromatography (HPLC) is the method of separation and purification of chemical compounds dissolved in various mixtures of aqueous and organic solvents.
The main principle of the separation is the different affinity of chemicals under study to the stationary phase which results in different times every component takes to come through the separation column.
www.chem.stevens.edu /Polymer_Lab/PolymerLab.shtml   (787 words)

  
 Chemical Biology - University of Michigan
Understanding how nature catalyzes the innumerable chemical reactions that occur in living organisms is a problem central to the field of chemical biology.
Several research groups are using combinations of physical, chemical, and genetic approaches to investigate the reaction mechanisms of both protein and RNA enzymes.
Members of the department are studying a wide range of biologically important chemical reactions, including the modification of proteins by lipid and carbohydrate groups, the generation of free radicals by enzymes, and how RNA molecules are specifically cleaved and processed in the cell.
www.umich.edu /~chembio   (754 words)

  
 Chemical Biology - BioChemWeb.org
The Chemical Generation of Molecular Diversity - Overview of diversity generation in combinatorial chemistry (diversity-oriented synthesis) describing pin technology, split-pool synthesis, iterative deconvolution, encoded libraries, phage libraries, peptoid libraries etc.
Biocatalysis/Biodegradation Database - "Microbial biocatalytic reactions and biodegradation pathways primarily for xenobiotic, chemical compounds." (University of Minnesota)
CAS, Chemical Abstracts Service - "CAS provides pathways to published research in the world's journal and patent literature--virtually everything relevant to chemistry plus a wealth of information in the life sciences and a wide range of other scientific disciplines--back to the beginning of the 20th century."
www.biochemweb.org /chemical.shtml   (1158 words)

  
 Home : Nature Chemical Biology
Announcing: Papers published in Nature Chemical Biology now appear in the ISI Web of Science and the MEDLINE database, which is searchable through PubMed
The ubiquitous disulfide bonds found in proteins have traditionally been thought of as resistant to chemical modification.
They were able to modify at least three different proteins by adding PEG to a 3-carbon bridge that they introduced between internal sulfur atoms.
www.nature.com /nchembio   (444 words)

  
 Chemical Biology Virtual Journal
An easy-to-use point of access to all chemical biology literature in the RSC's publications.
Chemical Biology, a supplement highlighting the chemical biology content of RSC journals, has been launched.
The latest issue of our new chemical biology journal has been published and includes an opinion, a highlight and several high quality primary papers....
www.rsc.org /Publishing/Journals/cb/index.asp   (200 words)

  
 Grants and Fellowships - Chemical Biology Initiative at the University of Minnesota
The development and use of these chemical probes is likely to have a major impact on our ability to development a deeper understanding of biology, which can be translated to the improvement of new therapeutic strategies (http://nihroadmap.nih.gov/).
TIRR proposals should be highly relevant to the development of chemical and biological experimental and computational tools that may have a large impact on the ability of University of Minnesota researchers to carry out chemical biological research.
Grantees will be required to provide the Chemical Biology Steering Committee with information for the annual report and to acknowledge CBI support on any work supported by the grant.
www.pharmacy.umn.edu /cbi/grants/home.html   (456 words)

  
 Home - Chemical Biology Initiative at the University of Minnesota
The Chemical Biology Initiative (CBI) is designed to stimulate and encourage interdisciplinary biomedical/biotechnology research, technological development, and education at the cross roads of chemistry, physics, biology, and engineering at the University of Minnesota.
Our central goal is to enable the development of a deeper understanding of biology that can be applied to the improvement of health.
On behalf of the Chemical Biology Interface Symposium planning committee, we are pleased to invite you to the Chemical Biology Interface Symposium which will be held Thursday, June 1st at the St. Paul campus.
www.pharmacy.umn.edu /cbi/home.html   (319 words)

  
 Chemical Biology home
You will be taught by experts in chemical and structural biology using a ‘problem-based’ approach.
The Chemical Biology course takes full advantage of these facilities through an extended research project supervised by two members of staff with complementary expertise.
Further information on the MSc in Chemical Biology may be obtained from us, email chembio@leeds.ac.uk.
www.chembio.leeds.ac.uk   (222 words)

  
 Harvard Department of Chemistry and Chemical Biology
Welcome to the library of the Chemistry and Chemical Biology Department.
The main emphasis of the Chemistry and Chemical Biology Library collection is primary literature published in journals.
In addition, the library collects graduate textbooks, monographs and serials in the fields of inorganic and bioinorganic chemistry, organic and bioorganic chemistry, medicinal chemistry, biochemistry, chemical biology and some material in the fields of molecular biology, physics, and surface science.
www-chem.harvard.edu /library   (219 words)

  
 Broad Institute - Chemical Biology Program   (Site not responding. Last check: 2007-11-05)
The annotation of an already remarkable set of small molecules, contributed from scientists worldwide, will be performed with a biologically and medically rich selection of assays.
Analyses of the compounds and their influences on a broad swath of biology will be enabled by the small-molecule database ChemBank V.2.0, sponsored by the NCI.
New England Patriots owner Robert Kraft and his wife Myra surprised attendees of the weekly Chemical Biology meeting with impromptu and inspirational words by the owner, noting the similarities between achieving success in the NFL and in chemical biology research.
www.broad.mit.edu /chembio   (201 words)

  
 Cornell News: Symposium on chemical biology   (Site not responding. Last check: 2007-11-05)
Chemical biology offers an important direction for where life sciences are headed in the future, McQuade says.
As part of the progression of ideas in biology, scientists began by identifying natural systems and moved on to studying how organisms behave.
They range from chemical synthesis to understanding how cells respond and interact with the outside world, a process called signal transduction.
www.news.cornell.edu /stories/April05/ChemBioSymposium.kr.html   (393 words)

  
 Schepartz Laboratory | Chemical Biology for Sophomores!
is a pair of courses in Yale College that expose sophomores to the excitement and creativity of cutting-edge research in chemical biology.
To illustrate to undergraduates, early in their careers, that chemical biology is an exciting, dynamic, and expanding field;
To demonstrate that the pursuit of knowledge through creative and rigorous research – the work that scientists actually do – is intellectually satisfying and unbelievably fun.
www.schepartzlab.yale.edu /chembiolsoph   (155 words)

  
 Chemistry Training Track
Chuo Chen -- Naturalproduct synthesis, synthetic methodology development, small molecule library synthesis and chemical biology.
Thomas Kodadek -- Biochemistry of transcriptional regulation, chemical biology, proteomics.
Joseph Ready -- Discovery and application of new chemical reactions; total synthesis of complex molecules.
www8.utsouthwestern.edu /utsw/cda/dept23109/files/92379.html   (442 words)

  
 Harvard University Department of Chemistry&Chemical Biology
We are pleased to announce that Alan Saghatelian will be joining CCB as Assistant Professor, Chemistry and Chemical Biology, effective July 1, 2006.
We are pleased to announce that Tobias Ritter will be joining CCB as Assistant Professor, Chemistry and Chemical Biology, effective July 1, 2006.
Professor of Chemistry and Chemical Biology X. Sunney Xie is one of six Harvard affiliates elected as fellows by the American Association for the Advancement of Science (AAAS)
www.chem.harvard.edu   (464 words)

  
 Cornell/Rockefeller/Sloan-Kettering Tri-Institutional Training Program in Chemical Biology
The Tri-Institutional Training Program in Chemical Biology (TPCB) is a new generation of interdisciplinary study that seeks to recruit highly qualified students for a unique educational opportunity.
The TPCB is a joint collaboration among Cornell University in Ithaca, The Rockefeller University, Memorial Sloan-Kettering Cancer Center, and the Weill Medical College of Cornell, all in New York City.
The program blends educational and research experience on all four campuses and provides a unique training environment at the forefront of chemistry and biomedical research.
www.triiprograms.org /tpcb.html   (103 words)

  
 Rutgers Department of Chemistry and Chemical Biology
In Rutgers' Chemistry and Chemical Biology Department, education and research go hand in hand.
A major goal of our program is to train research scientists to create new knowledge in their careers as leaders in academe, industry or government.
The contest is being sponsored by the Center for Molecular Biophysics and Biophysical Chemistry, the BioMaPS Institute, the Protein Data Bank, and the Center for Advanced Biotechnology and Medicine.
rutchem.rutgers.edu   (251 words)

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