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| | eMedicine - Pneumonia, Aspiration : Article by Basil Varkey, MD, FRCPC, FCCP (Site not responding. Last check: 2007-10-16) |
 | | The initial chemical burn is followed by an inflammatory cellular reaction fueled by the release of potent cytokines, eg, tumor necrosis factor–alpha and interleukin-8. |
 | | In anaerobic pneumonia, the pathogenesis is related to the large volume of aspirated anaerobes (eg, as in persons with periodontal disease) and to host factors (eg, as in alcoholism) that suppress cough, mucociliary clearance, and phagocytic efficiency. |
 | | Chemical pneumonia: Treatment should include maintenance of airways and clearance of secretions with tracheal suctioning, oxygen supplementation, mechanical ventilation if the patient is unable to maintain adequate oxygenation, early use of positive end-expiratory pressure (PEEP), and administration of intravenous fluids. |
| www.emedicine.com /MED/topic175.htm (2688 words) |
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