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Topic: Chemokine

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	Chemokine - Wikipedia, the free encyclopedia
		All chemokines have molecular masses of between 8 and 10 kDa and are approximately 20-50% identical.
		Chemokines are released from a wide variety of cells in response to bacterial infection, viruses and agents that cause physical damage such as silica or the urate crystals that occur in gout.
		Members of the chemokine family fall mostly into two broad groups-CC chemokines (or β-chemokines) with two adjacent cysteines near the amino terminus of the protein, and CXC chemokines (or α-chemokines) in which the cysteines are separated by an amino acid.
	en.wikipedia.org /wiki/Chemokine (721 words)

	Search AEGIS (Site not responding. Last check: 2007-11-03)
		Involvement of chemokine receptors in the induction of interferon by HIV-1.
		Chemokine receptors are G protein-coupled receptors that mediate migration and activation of leukocytes as an important part of a protective immune response to injury and infection.
		The chemokine receptors CCR3, CCR5, and CXCR4 are...
	www.aegis.com /search/qk.asp?topic=chemokine+receptor&CiScope=pubs (15358 words)

	Chemokine Information available thru RDI Divison of Fitzgerald Industries Intl
		The chemokines are 8-16 kDa soluble proteins produced and released by a wide variety of cell types during the initial phase of host response to injury, allergens, antigens, or invading microorganisms.
		The a chemokines have a single amino acid inserted between the first and second of their four cysteine residues, whereas these cysteines are not separated in the B group.
		The chemokines are thought to competitively block entry of HIV-1 in a passive manner by binding to the chemokine receptor.
	www.researchd.com /cytokines/chemokin.htm (879 words)

	Chemokine definition - Medical Dictionary definitions of popular medical terms
		Chemokine: One of a large group of proteins that act as lures and were first found attracting white blood cells.
		The chemokines are involved in a wide variety of processes including acute and chronic types of inflammation, infectious diseases, and cancer.
		Most chemokines belong to one of two major subfamilies -- the CXC and CC subfamilies -- based on the arrangement of the first two of the 4 cysteine residues.
	www.medterms.com /script/main/art.asp?articlekey=2695 (258 words)

	Chemokine Therapeutics - Press Releases
		Chemokine Therapeutics is a product-focused biotechnology company developing drugs in the field of chemokines.
		Chemokines are a class of signaling proteins which play a critical role in the growth, differentiation and maturation of cells necessary for fighting infection, and stem cells, as well as tissue repair and regeneration.
		Chemokine Therapeutics is a leader in research in the field of chemokines and has several products in various stages of development.
	www.chemokine.net /news_releases.htm (650 words)

	Chemokine Regulation of Normal and Pathologic Immune Responses -- Christopherson and Hromas 19 (5): 388 -- Stem Cells (Site not responding. Last check: 2007-11-03)
		In autoimmune diseases, chemokines are implicated in the pathology
		The Exodus subfamily of cc chemokines inhibits the proliferation of chronic myelogenous leukemia progenitors.
		Nakano H, Gunn MD. Gene duplications at the chemokine locus on mouse chromosome 4: multiple strain-specific haplotypes and the deletion of secondary lymphoid-organ chemokine and EBI-1 ligand chemokine genes in the plt mutation.
	stemcells.alphamedpress.org /cgi/content/full/19/5/388 (3966 words)

	Chemokines in joint disease: the key to inflammation? -- Haringman et al. 63 (10): 1186 -- Annals of the Rheumatic ... (Site not responding. Last check: 2007-11-03)
		diseases, the in vitro and in vivo characteristics of the chemokine
		Figure 2 Expression of chemokine and chemokine receptor staining in RA ST. CCR1 positive cells are scattered throughout the synovium, and are expressed predominantly by macrophages.
		Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses.
	ard.bmjjournals.com /cgi/content/full/63/10/1186 (6333 words)

	Chemokine Receptor Polyclonal antibodies available through Research Diagnostics Inc
		CCR3 is the receptor for eotaxin and a novel CC Chemokine, leukotactin-1.
		The chemokine receptor CCR5 is one of the co-receptors used by primary isolates of HIV-1.
		identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK.
	www.researchd.com /cytokines/chempoly.htm (2960 words)

	Chemokines: role in inflammation and immune surveillance -- Moser and Willimann 63 (Supplement 2): ii84 -- Annals of ... (Site not responding. Last check: 2007-11-03)
		Chemokine receptors are embedded into the membrane by seven transmembrane domains.
		The NH -terminus and three extracellular loop regions are involved in chemokine binding, and the COOH-terminus and three intracellular loop regions participate in G-protein mediated signal transduction.
		for inflammatory chemokines and adhesion molecules that are
	ard.bmjjournals.com /cgi/content/full/63/suppl_2/ii84 (3740 words)

	Chemokines and chemokine receptors in leukocyte trafficking -- Olson and Ley 283 (1): 7 -- AJP - Regulatory, ... (Site not responding. Last check: 2007-11-03)
		Chemokines (Table 1) are highly basic proteins of 70-125 amino acids with molecular masses ranging from 6 to 14 kDa (94).
		Chemokine receptor expression is also regulated by a variety of inflammatory stimuli (172).
		Chemokine involvement in dendritic cell and lymphocyte trafficking to and from secondary lymphoid organs.
	ajpregu.physiology.org /cgi/content/full/283/1/R7 (7734 words)

	chemokine :: Molecules of HIV
		They aren't only used in the immune system - they also serve a purpose in related systems such as wound healing - but the majority of them in the body are secreted by T cells.
		A chemokine is a type of cytokine produced in acute and chronic inflammation, with the specific role of mobilising and activating white blood cells.
		This is because chemokines compete with HIV to attach to chemokine receptors such as CCR5, CXCR4 and CXCR5, which HIV uses as coreceptors.
	www.mcld.co.uk /hiv/?q=chemokine (197 words)

	Chemokine Therapeutics is a biotechnology company with expertise in chemokine based drugs
		Chemokine Therapeutics is a biotechnology company with expertise in chemokine based drugs
		Chemokine Therapeutics Corp. discovers and develops peptide analogs of chemokines for cancer treatment, and immune system recovery.
		Chemokine Therapeutics Corp. is a publicly-held biotechnology company with expertise in chemokine-based drugs.
	www.chemokine.net (68 words)

	Hydrogen Peroxide Induces Murine Macrophage Chemokine Gene Transcription Via Extracellular Signal-Regulated Kinase- and ... (Site not responding. Last check: 2007-11-03)
		of chemokines in response to oxidative stress (3).
		in the expression of several chemokines (34, 35).
		Chemokines are critical protein factors responsible for the activation
	www.jimmunol.org /cgi/content/full/169/12/7026 (5921 words)

	Welcome to Torrey Pines Biolabs
		Located in Houston, Torrey Pines Biolabs is specialized in providing quality immunological reagents to the chemokine and cytokine research community.
		Our major product line for chemokines and cytokines can be accessed through Internet, at www.chemokine.com.
		Through our tireless research effort, we continue to bring to the research community new antibodies that are suitable for immmunoprecipitation, immunohistochemistry, western blot, and neutralization assays.
	www.chemokine.com (72 words)

	{beta}-Chemokine Induction of Activation Protein-1 and Cyclic AMP Responsive Element Activation in Human Myeloid Cells ... (Site not responding. Last check: 2007-11-03)
		Chemokine receptors are members of the group of seven-transmembrane
		Kinase activity was measured by densitometry, and the values on the Y axes reflect the fold of kinase activity induced by chemokines versus the basal activity (kinase activity before chemokine treatment).
		Arai H., Charo I. Differential regulation of G-protein-mediated signaling by chemokine receptors.
	cgd.aacrjournals.org /cgi/content/full/12/4/211 (6434 words)

	Obstructive Nephropathy in the Mouse: Progressive Fibrosis Correlates with Tubulointerstitial Chemokine Expression and ... (Site not responding. Last check: 2007-11-03)
		Chemokine mRNA was detected by a multiprobe RNase protection assay (RPA) and quantified by image densitometry after normalization to glyceraldehyde phosphate dehydrogenase (GAPDH) expression, as described in the Materials and Methods section.
		Chemokine receptor expression was detected by a multiprobe RPA and quantified by image densitometry after normalization to GAPDH expression.
		Rovin BH: Chemokine blockade as a therapy of renal disease.
	jasn.asnjournals.org /cgi/content/full/12/6/1173 (6774 words)

	Keystone Symposia Conference \| Chemokines and Chemokine Receptors - Program
		The Chemokine Decoy Receptor D6 Protects the Fetus from Inflammation Acting as an Inflammatory CC Chemokine Scavenger at the Fetal-Maternal Interface
		Short Talk: The Chemokine Receptor CXCR3 is Replenished at the Cell Surface by de novo Synthesis of Receptor and not by Receptor Recycling
		Promiscuous Chemokine Sequestration By a Herpesvirus Decoy Receptor
	www.keystonesymposia.org /Meetings/ViewMeetings.cfm?MeetingID=795 (1209 words)

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