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Topic: Cholestyramine

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	Cholestyramine and its role in C. difficile infections
		C. Kurtz and associates confirmed the use of cholestyramine in the treatment for C. difficile colitis in some patients, however, stated that the resin has shown only modest activity and is not recommended for use in patients with severe cases of C. difficile colitis.
		Kelly CP and LaMont JT reported that the response rate to cholestyramine in patients with C. difficile colitis is associated with a better overall response rate of 68 percent compared to colestipol (36 versus 22 percent with placebo).
		Cholestyramine should be given two to three hours apart from vancomycin to prevent it from binding with vancomycin.
	www.globalrph.com /cholestyramine.htm (747 words)

	Howstuffworks "Cholestyramine: A Profile of a Cholesterol Drug"
		Cholestyramine is used to lower levels of cholesterol in the blood and to treat the itching that is associated with liver disease.
		Cholestyramine chemically binds to bile salts in the gastrointestinal tract and thereby prevents the body from producing cholesterol.
		Although cholestyramine appears to be safe (because very little is absorbed into the bloodstream), extensive studies in humans during pregnancy have not been conducted.
	health.howstuffworks.com /define-cholestyramine.htm (790 words)

	Cholestyramine (Site not responding. Last check: 2007-10-16)
		Cholestyramine is prescribed, along with dietary changes (restriction of cholesterol and fat intake), to reduce low-density lipoprotein (LDL) and total cholesterol.
		Cholestyramine works by attaching to bile acids in the intestine, and both are removed from the body as waste.
		Before cholestyramine is prescribed, tell your health care provider about any other medicines you are taking (especially digoxin, beta blockers, thyroid hormone, and anticoagulant medications such as Coumadin).
	clevelandclinic.org /health/health-info/docs/0600/0671.asp?index=4797 (1026 words)

	A COMPARISON OF THE ANTIBIOTIC ENROFLOXACIN AND CHOLESTYRAMINE THERAPY IN NEONATAL DIARRHEIC CALVES
		Cholestyramine is a non-absorbable anion exchange resin that is used predominantly for the treatment of hypercholesterolemia in adults and the management of acute diarrhea in children (3).
		Cholestyramine treatment of newborn infectious diarrhea has been shown to be effective (4).
		In conclusion, cholestyramine may be used in preference to antibacterial therapy in the treatment of neonatal diarrhea.
	www.isrvma.org /article/54_1_6.htm (609 words)

	Cholestyramine (Site not responding. Last check: 2007-10-16)
		Cholestyramine is prescribed, along with dietary changes (restriction of cholesterol and fat intake), to reduce low-density lipoprotein (LDL) and total cholesterol.
		Cholestyramine works by attaching to bile acids in the intestine, and both are removed from the body as waste.
		Before cholestyramine is prescribed, tell your health care provider about any other medicines you are taking (especially digoxin, beta blockers, thyroid hormone, and anticoagulant medications such as Coumadin).
	www.clevelandclinic.org /health/health-info/docs/0600/0671.asp?index=4797 (1040 words)

	Parkinsn's List Drug DataBase cholestyramine / Questran
		Originally, cholestyramine was used to treat pruritis secondary to cholestasis, but its main use today is to treat hypercholesterolemia with concomitant hypertriglyceridemia.
		Cholestyramine is relatively contraindicated in constipated patients because of the danger of fecal impaction.
		Cholestyramine is relatively contraindicated in patients with renal disease because colestipol releases chloride, which can increase the risk of developing hyperchloremic metabolic acidosis.
	www.parkinsons-information-exchange-network-online.com /drugdb/030.html (1373 words)

	Medbroadcast Drug Info (Site not responding. Last check: 2007-10-16)
		Cholestyramine resin belongs to the class of medications known as bile acid sequestrants.
		Cholestyramine resin may be used for symptomatic control of bile-induced diarrhea due to short bowel syndrome and may also be used to relieve itchiness associated with partial blockage of bile ducts.
		Pregnancy: Since cholestyramine resin is not absorbed by the body, it is not expected harm to the baby during pregnancy if taken in recommended doses.
	www.medbroadcast.com /drug_info_details_pf.asp?brand_name_id=51 (931 words)

	Cholestyramine Indications (Site not responding. Last check: 2007-10-16)
		Cholestyramine is one fo the few lipid reducers for which a primary preventive use against myocardial infarctions has been demonstrated.
		A study, in which 1000 men with hypercholesterolemia were treated with cholestyramine for one year, demonstrated an infarction incidence reduced by 2 or 3 cases.
		Cholestyramine is only indicated in cases for which improved healing rates can be anticipated.
	www.infomed.org /100drugs/clstind.html (175 words)

	Data Sheet
		Questran Powder (cholestyramine resin), the chloride salt of a basic anion exchange resin, is a cholesterol lowering agent intended for oral administration.
		Cholestyramine resin adsorbs and combines with the bile acids in the intestine to form an insoluble complex which is excreted in the faeces.
		Because cholestyramine binds bile acids, Questran Light may interfere with normal fat digestion and absorption and this may prevent absorption of fat soluble vitamins A, D and K. When Questran Light is given for long periods of time, concomitant supplementation with water-miscible (or parenteral) form of vitamins A, D and K should be considered.
	www.medsafe.govt.nz /profs/Datasheet/q/QuestranLightsus.htm (2166 words)

	Cholestyramine.
		The medicament is also used to relieve itching caused by high levels of bile acids in the blood, a problem associated with blockage of the bile ducts.
		Cholestyramine may also be used to prevent some types of diarrhea.
		Cholestyramine binds with bile acids in the intestine, forming an insoluble complex that is excreted in the feces.
	www.herbs2000.com /medica/cholestyramine.htm (464 words)

	Patient Education - Drugs - cholestyramine
		Cholestyramine is also used to lower the cholesterol level and to bind up various toxins or poisons that may have been ingested.
		Cholestyramine is ranked C. However, since this drug is not absorbed but remains in the intestinal tract, it is probably safe during pregnancy.
		Sipping cholestyramine mixtures or holding it in your mouth for a long period of time can lead to tooth discoloration, enamel erosion or decay.
	www.gicare.com /pated/cholestyramine.htm (943 words)

	Cholestyramine (Oral) - MayoClinic.com (Site not responding. Last check: 2007-10-16)
		Cholestyramine (koe-less-TEAR-a-meen) is used to lower high cholesterol levels in the blood.
		Cholestyramine is also used to remove substances called bile acids from your body.
		Cholestyramine is not absorbed into the body and is not likely to cause problems.
	www.mayoclinic.com /health/drug-information/DR202137 (1438 words)

	cholestyramine, Questran - drug class, medical uses, medication side effects, and drug interactions by MedicineNet.com
		STORAGE: Store at room temperature, 15-30°C (59-86°F) Cholestyramine is used for reducing cholesterol levels in the blood, to relieve the itching of liver and biliary disease, and to treat overdoses of digoxin or thyroid hormone.
		Cholestyramine also is recommended for the rapid elimination of leflunomide (Arava).
		Cholestyramine decreases the conversion of leflunomide (Arava) to its active form and reduces the absorption of vitamin A, D, E and K. Use of cholestyramine in pregnant women has not been adequately evaluated.
	www.medicinenet.com /cholestyramine/article.htm (649 words)

	Carilion - Cholestyramine for kidney stones - [Medication]
		Cholestyramine attaches to bile in the intestine, which limits how much oxalate your intestines absorb.
		Cholestyramine is used in people with high levels of oxalate, especially those who also have inflammatory bowel disease (IBD).
		Cholestyramine is more commonly used to help lower the amount of cholesterol in the blood to reduce the risk of heart disease.
	www.carilion.com /kbase/htm/tw95/51/tw9551.htm (195 words)

	Cholestyramine - Wikipedia, the free encyclopedia
		Cholestyramine (Questran®, Questran Light®, Cholybar®) is a bile acid sequestrant, which binds bile in the gastrointestinal tract to prevent its reabsorption.
		It is primarily used to treat hypercholesterolemia, but can also used to treat the pruritus, or itching, that often occurs during liver failure due to the liver's inability to eliminate bile.
		Cholestyramine is available as powder form, in 4 gram packets.
	en.wikipedia.org /wiki/Cholestyramine (166 words)

	Pediatric Oncall- PATIENT INFORMATION ABOUT BILIARY ATRESIA
		Cholestyramine – This comes in the form of a powder in individual sachets.
		As your baby becomes older and manages larger volumes the daily dose of Cholestyramine can be given all at once or split into two.
		For a toddler or an older child needing Cholestyramine, it is best given in one or two doses away from the main meal times and vitamins.
	www.pediatriconcall.com /forpatients/commonchild/biliaryArt7.asp (420 words)

	cholestyramine - [Medication]
		Cholestyramine is used to lower high levels of cholesterol in the blood.
		Cholestyramine has also been used to treat the itching that is associated with a blockage of the biliary tract.
		Cholestyramine is in the FDA pregnancy category C. This means that it is not known whether cholestyramine will harm an unborn baby.
	www.peacehealth.org /kbase/multum/d00193a1.htm (1287 words)

	Ask an Expert: Cholestyramine: cure for fibromyalgia?
		Fibromyalgia is a chronic debilitating disease of unknown origin, which manifests as widespread musculoskeletal pain and stiffness associated with fatigue, poor sleep, neuroendocrine disorders, psychological distress including anxiety and depression and the presence of discrete tender points.
		They further think that a defined visual contrast sensitivity (VCS) test can be used as a marker of exposure to neurotoxins in general, and that improvements in VCS test results parallel both improvements in fibromyalgia symptoms and reduction of total body load of the toxin.
		Cholestyramine is available by prescription from your doctor.
	www.netwellness.org /question.cfm/25488.htm (958 words)

	Cholestyramine and Loperamide References
		"Cholestyramine also binds fat soluble and bacterial toxins and is effective in the treatment of enterotoxaemia if it is given in the early stages of the disease.
		Cholestyramine is a[n inert] granular [ion exchange] resin with an affinity to hydrophobic compounds.
		The infants receiving cholestyramine also had a better weight gain than those receiving the placebo, and their metabolic acidosis was corrected sooner.
	homepage.mac.com /mattocks/morfz/questran.html (791 words)

	Prevalite side effects (Site not responding. Last check: 2007-10-16)
		Cholestyramine is used to lower high levels of cholesterol in the blood.
		Cholestyramine has also been used to treat the itching that is associated with a blockage of the biliary tract.
		Cholestyramine is in the FDA pregnancy category C. This means that it is not known whether cholestyramine will harm an unborn baby.
	www.medicationadvisor.com /side_effects/Prevalite.htm (1536 words)

	Medical Dictionary: Cholestyramine - WrongDiagnosis.com
		Cholestyramine resin adsorbs and combines with bile acids in the intestine to form an insoluble complex, which is then excreted in the feces.
		As a result, the absorption of bile acids from the enterohepatic circulation is partially prevented, resulting in an increased oxidation of cholesterol to bile acids, a decrease in low density lipoprotein in the plasma, and a decrease in serum cholesterol levels.
		Cholestyramine : strongly basic anion exchange resin used to extract bile salts and cholesterol, to treat diarrhea and biliary obstruction, and as an antipruritic.
	www.wrongdiagnosis.com /medical/cholestyramine.htm (327 words)

	Low-Dose Combined Therapy with Fluvastatin and Cholestyramine in Hyperlipidemic Patients -- Sprecher et al. 120 (7): ...
		In the combined therapy groups, cholestyramine, 8 mg/d, was added in phase 2 and the dose increased to 16 mg/d in phase 3.
		Increased LDL cholesterol reductions were seen with the addition of cholestyramine, 8 g/d, in phase 2 (weeks 9 to 16), and modest additional reductions occurred when the dose was increased to 16 g/d in phase 3 (weeks 17 to 24).
		Pharmacokinetics and pharmacodynamics of pravastatin alone and with cholestyramine in hypercholesterolemia.
	www.annals.org /cgi/content/full/120/7/537 (3605 words)

	From CRS: Substances which absorb energy from food
		In the in vitro studies, we determined the adsorption capacity (Qm) of cholestyramine and activated charcoals for cholesterol in glacial acetic acid.
		For the bile salt sodium desoxycholate in ammonia: sodium bicarbonate, pH 8.2, the Qm with cholestyramine was 4641 +/- 2669 and with Super Char was 2814 +/- 667 (p = 0.11).
		In general, the acceptability by the patients and the efficacy of activated charcoal, cholestyramine and their combination were about equal, but there were individual preferences for particular treatments.
	darkwing.uoregon.edu /~freinkel/cr/crspsgs/hunger1.htm (2303 words)

	Cholestyramine Therapy for Dyslipidemia in Non-Insulin-dependent Diabetes Mellitus: A Short-Term, Double-Blind, ... (Site not responding. Last check: 2007-10-16)
		Cholestyramine Therapy for Dyslipidemia in Non-Insulin-dependent Diabetes Mellitus: A Short-Term, Double-Blind, Crossover Trial -- Garg and Grundy 121 (6): 416 -- Annals of Internal Medicine
		Cholestyramine therapy was well tolerated by our patients.
		Cholestyramine resin therapy for hypercholesteremia: clinical and metabolic studies.
	www.annals.org /cgi/content/full/121/6/416 (3845 words)

	Hepatitis C, Questran, Cholestyramine
		Since cholestyramine is not absorbed into the body, these substances also pass out of the body without being absorbed.
		Older adults—Side effects may be more likely to occur in patients over 60 years of age, who are usually more sensitive to the effects of cholestyramine.
		Side Effects of this Medicine—In some animal studies, cholestyramine was found to cause tumors.
	www.hepatitis-central.com /hcv/drugs/questran.html (1701 words)

	JAMA -- Abstract: A multicenter comparison of lovastatin and cholestyramine therapy for severe primary ...
		JAMA -- Abstract: A multicenter comparison of lovastatin and cholestyramine therapy for severe primary hypercholesterolemia.
		A multicenter comparison of lovastatin and cholestyramine therapy for severe primary hypercholesterolemia.
		cholestyramine resin group, 13% of the 20-mg lovastatin group, and 14% of
	jama.ama-assn.org /cgi/content/abstract/260/3/359 (355 words)

	Bile Acid Sequestrants, Cholestyramine, Prevalite, Questran
		Cholestyramine (Questran®) and colestipol (Colestid®) are bile acid sequestrants—a class of drugs that binds bile acids, prevents their reabsorption from the digestive system, and reduces cholesterol levels.
		Cholestyramine and colestipol are two of many drugs used to lower cholesterol levels in people with high cholesterol.
		Bile acids are produced in the liver from cholesterol and secreted into the small intestine to help with the absorption of dietary fat and cholesterol.
	www.truestarhealth.com /Notes/1322001.html (582 words)

	MedlinePlus Drug Information: Cholestyramine Resin
		Cholestyramine is used with diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in your blood.
		Cholestyramine comes in a chewable bar and in a powder that must be mixed with fluids or food.
		This precaution is especially important if you also take other drugs; changing your cholestyramine dose may change their effects.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a682672.html (871 words)

	warfarinfo
		Because cholestyramine is a resin which is not absorbed from the intestine, it would seem that this interaction is strictly one of inhibiting absorption.
		However, since the cholestyramine is not absorbed and has few side effects other than diarrhea, it would seem to cause no harm to try to eliminate excess warfarin (Coumadin, Jantoven) in this manner.
		MY COMMENT-- I question whether the cholestyramine had any effect on the warfarin (Coumadin, Jantoven) since this dose of vitamin K, alone, should have returned the INR to this level in the same length of time.
	www.warfarinfo.com /cholestyramine.htm (330 words)

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