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Topic: Chromaffin cell

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Endocrine system

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	Chromaffin-adrenocortical cell interactions: effects of chromaffin cell activation in adrenal cell cocultures -- ...
		Chromaffin cell activation resulted in time-dependent enhancement of neurite number (B), neurite length (C), number of branches per neurite (D), tyrosine hydroxylase immunoreactivity (TOH-IR; on a relative scale of 1-4; E), and the number of contacts formed between chromaffin and adrenocortical cells (F).
		Furthermore, in the absence of chromaffin cells (Fig.
		The purity of the Percoll-purified adrenocortical cell fraction is demonstrated by the presence of only adrenocortical cells in the micrographs, compared with the presence of adrenocortical cells, chromaffin cells, and other unidentified cell types in the other figures.
	ajpcell.physiology.org /cgi/content/full/280/1/C61 (4529 words)

	Light and Electron Microscopic Study of Changes in the Organization of the Cortical Actin Cytoskeleton During ...
		Chromaffin cells were cultured on Formvar-coated grids for 48 hr and then incubated with Locke's solution in the presence of 10 µM nicotine for 40 sec.
		Cells were cultured, stimulated, and treated as indicated in legend to Figure 2.
		Chromaffin cells were cultured on Formvar-coated grids for 48 hr and then incubated with Locke's solution for 40 sec in the absence (A) or presence (B) of 10 µM nicotine.
	www.jhc.org /cgi/content/full/46/2/193 (4700 words)

	Fine structure of host-graft relationships between transplanted chromaffin cells and CNS -- PAPPAS 13 (9002): 277 -- ...
		The close proximity of robust plasma cells of the host with the implanted chromaffin cells suggest that these plasma cells may be secreting idiotypic antibodies that promote and support the long-term survival of these allografts.
		Electron micrograph showing a portion of a bovine chromaffin cell (N, nucleus of chromaffin cell) implanted on the surface of the lumbar spinal cord in the subarachnoid space of a rat.
		Pappas, G. D., Sagen, J. (1988) The fine structure of chromaffin cell implants in the pain modulatory regions of the rat periaqueductal gray and spinal cord.
	www.fasebj.org /cgi/content/full/13/9002/S277 (1977 words)

	Protocol: Bovine chromaffin cell isolation
		The cells are then spun at 13,000 rpm (=20,000 G) at RT for 20 min (SS34 rotor, Sorvall).
		Chromaffin cells band in the middle of the tube (though you may not actually see a discrete chromaffin cell band; rather, a hazy layer), and cellular debris accumulates in the upper portion of the gradient.
		Collect the middle chromaffin cell layer (~50-60% of the gradient volume; 10-15 ml) with a 10 ml pipette.
	medicine.ucsd.edu /hypertension/list_of_protocols/18_CC_isolation.htm (1281 words)

	p245 : Chromaffin Cell Function and Structure is Impaired in Corticotropin-Releasing Hormone Receptor Type 1-Null Mice (Site not responding. Last check: 2007-10-29)
		Chromaffin Cell Function and Structure is Impaired in Corticotropin-Releasing Hormone Receptor Type 1-Null Mice
		On the ultrastructural level, chromaffin cells in saline-treated CRHR1 null mice exhibited a marked depletion in epinephrine-storing secretory granules that was not restored by ACTH-treatment.
		In conclusion, CRHR1 is required for a normal chromaffin cell structure and function and deletion of this gene is associated with a significant impairment of epinephrine biosynthesis.
	www.thieme.de /abstracts/eced/abstracts2002/daten/p245.html (334 words)

	Calcium Entry through L-type Calcium Channels Causes Mitochondrial Disruption and Chromaffin Cell Death -- Cano-Abad et ...
		Preparation and Culture of Bovine Chromaffin Cells-- Bovine adrenal medullary chromaffin cells were isolated as previously described (28) with some modifications (29).
		a, cell death expressed as a percentage of LDH released to the external medium in chromaffin cells incubated for 24 h with increasing concentrations of [K
		Cell death measured as LDH released in the first 30 min was completely counteracted when SOD and nimodipine were present during
	www.jbc.org /cgi/content/full/276/43/39695 (5035 words)

	biology - Chromophil
		chromaffin) cell readily absorbs chromium salts which are used in histology to increase the contrast of samples for microscopy.
		Chromophil cells are mostly hormone producing cells containing so called chromaffin granules.
		Chromophil cells therefore belong to the group of APUD (amine precursor uptake and decarboxylation) cells.
	www.biologydaily.com /biology/Chromophil (115 words)

	Acute Modulation of Adrenal Chromaffin Cell BK Channel Gating and Cell Excitability by Glucocorticoids -- Lovell et al. ...
		Glucocorticoids at lower concentrations typically increased peak BK current in rat chromaffin cells, although substantial variability was seen at all concentrations in both species.
		In the bovine cell, higher doses of DEX progressively raised the maximum number of spikes that could be elicited from the cell.
		For the rat cell in F, as well as in D, 10 µm did not produce a bigger effect than 1 µm, as was typically seen in the bovine cells.
	jn.physiology.org /cgi/content/full/91/1/561 (6475 words)

	Chromaffin Cell F-actin Disassembly and Potentiation of Catecholamine Release in Response to Protein Kinase C ...
		Chromaffin Cell F-actin Disassembly and Potentiation of Catecholamine Release in Response to Protein Kinase C Activation by Phorbol Esters Is Mediated through Myristoylated Alanine-rich C Kinase Substrate Phosphorylation -- Rosé et al.
		Following these treatments, the cells were fixed and processed for rhodamine-labeled phalloidin staining as indicated under "Experimental Procedures." A, image analysis of control (panel a) and PMA- and Ca -treated (panel b) cells stained with rhodamine phalloidin.
		Regulated secretion in chromaffin cells is triggered by an increase in intracellular Ca However, despite the fact that Ca participation in neurosecretion was observed many years ago (41-43),
	www.jbc.org /cgi/content/full/276/39/36757 (5250 words)

	Ultrastructural Organization of Bovine Chromaffin Cell Cortex---Analysis by Cryofixation and Morphometry of Aspects ...
		The size of chromaffin cells was estimated from measurements of diameters of the cells in culture.
		Cortical filamentous actin disassembly and scinderin redistribution during chromaffin cell stimulation precede exocytosis, a phenomenon not exhibited by gelsolin.
		Chromaffin cell cortical actin network dynamics control the size of the release-ready vesicle pool and the initial rate of exocytosis.
	www.jcb.org /cgi/content/full/139/7/1709 (6901 words)

	Secretion Control in Adrenal Chromaffin Cells (Site not responding. Last check: 2007-10-29)
		Neuroendocrine chromaffin cells of the adrenal medulla receive individual innervation through the splanchnic nerve.
		The accessibility of these cells make them a useful model system for the study of vesicle exocytosis in neurons as well as other excitable secretory cells.
		It is the main goal of the chromaffin cell group to better understand the manner in which the secretory vesicles reach a release-ready state and then undergo evoked fusion with the plasma membrane.
	www.mpibpc.gwdg.de /abteilungen/140/projects/Chromaffin.html (521 words)

	Chromaffin-adrenocortical cell interactions: effects of chromaffin cell activation in adrenal cell cocultures -- ...
		Chromaffin-adrenocortical cell interactions: effects of chromaffin cell activation in adrenal cell cocultures -- Shepherd and Holzwarth 280 (1): C61 -- AJP - Cell Physiology
		Chromaffin-adrenocortical cell interactions: effects of chromaffin cell activation in adrenal cell cocultures
		cells were used, selective chromaffin cell activation dramatically
	ajpcell.physiology.org /cgi/content/abstract/280/1/C61 (183 words)

	Development of chromaffin cells depends on MASH1 function -- Huber et al. 129 (20): 4729 -- Development
		The sympathoadrenal (SA) cell lineage is a derivative of the
		At least 100 cells per group were analyzed in random sections through different levels of the adrenal gland.
		Cells that are positive for TH and PNMT appear yellow.
	dev.biologists.org /cgi/content/full/129/20/4729 (5527 words)

	Evidence for hypoxia-induced neuronal-to-chromaffin metaplasia in neuroblastoma -- HEDBORG et al. 17 (6): 598 -- The ...
		IGF2-expressing cells in the center of tumor nodules are surrounded by neuroblastic stroma-apposed cells forming a regular pattern of rosettes (marked by yellow circles in panel C) leading to a "punched-out holes" appearance in panel A.
		Large ganglion cell-like cells (asterisks) are mainly present in peripheral parts of the nodule (I), whereas central cells express chromaffin markers and display distinct morphological features, consisting of specific nuclear morphology (fl arrows), smaller size, ovoid cell shape with a relatively thick cell process with varicosities extending from one pole.
		In SH-SY5Y cells, the chromaffin-like change in expression of IGF2/GAP-43 was reversed within 24 h of cessation of near-anoxia with slower kinetics than that of VEGFA expression (D).
	www.fasebj.org /cgi/content/full/17/6/598 (6259 words)

	Cellml.org - Modelling Stimulation-Sectretion Coupling in a Chromaffin Cell (Site not responding. Last check: 2007-10-29)
		Adrenal chromaffin cells have been used extensively for studying the mechanisms involved in stimulation-secretion coupling, namely electrophysiological progesses, signal transduction pathways, calcium homeostasis, and exocytotic processes.
		This model is able to simulate the cell's secretory responses, including the process of stimulation-secretion coupling.
		Modeling of stimulation-secretion coupling in a chromaffin cell, A. Warashina and T. Ogura, 2004, European Journal of Physiology, 448, 369-391.
	www.cellml.org /examples/repository/warashina_model_2004_doc.html (292 words)

	Desensitisation of chromaffin cell nicotinic receptors does not impede catecholamine secretion during acute hypoxia in ...
		Desensitisation of chromaffin cell nicotinic receptors does not impede catecholamine secretion during acute hypoxia in rainbow trout (Oncorhynchus mykiss) -- Lapner et al.
		Desensitisation of chromaffin cell nicotinic receptors does not impede catecholamine secretion during acute hypoxia in rainbow trout (Oncorhynchus mykiss)
		of chromaffin cell nicotinic receptors and (ii) to assess the ability of
	jeb.biologists.org /cgi/content/abstract/203/10/1589 (425 words)

	WCP: Subarachnoid Chromaffin Cell Allograft is Effective Analgesic in Patients with Terminal Cancer Pain (Site not responding. Last check: 2007-10-29)
		SAN DIEGO, CA -- August 20, 2002 -- Subarachnoid chromaffin cell allograft is a safe and effective analgesic in patients with terminal cancer pain, according to a small study presented August 18th at the 10th World Congress on Pain (WCP).
		Four patients received active treatment with 2 mL of a suspension of chromaffin cells, which had been cultured in vitro for three days, injected into the subarachnoid space through a lumbar puncture.
		Immune function of the patients remained stable with immunosuppressants, indicating that subarachnoid chromaffin cell allograft is both safe and effective in patients with terminal cancer pain.
	www.pslgroup.com /dg/21b9c6.htm (380 words)

	Acute Modulation of Adrenal Chromaffin Cell BK Channel Gating and Cell Excitability by Glucocorticoids -- Lovell et al. ...
		Acute Modulation of Adrenal Chromaffin Cell BK Channel Gating and Cell Excitability by Glucocorticoids -- Lovell et al.
		Acute Modulation of Adrenal Chromaffin Cell BK Channel Gating and Cell Excitability by Glucocorticoids
		ability than bovine cells in the absence of glucocorticoids.
	jn.physiology.org /cgi/content/abstract/91/1/561 (237 words)

	Cognetix (Site not responding. Last check: 2007-10-29)
		Antagonism of voltage-gated calcium channels in small cell carcinomas of patients with and without Lambert-Eaton myasthenic syndrome by autoantibodies omega-conotoxin and adenosine.
		Unmasking the functions of the chromaffin cell alpha7 nicotinic receptor by using short pulses of acetylcholine and selective blockers.
		Characterization of nicotinic acetylcholine receptors in cultured arterial chemoreceptor cells of the cat.
	www.cognetix.com /news_publications.asp (4884 words)

	Veterinary Information - Tumors and Cancer in Cats (Site not responding. Last check: 2007-10-29)
		Sqaumous cell carcinomas are the most common tumor of the oral tissues in cats and they do occur with some frequency.
		This is a tumor of a specific cell (chromaffin cell) that exists in the adrenal gland.
		Monitoring of white blood cell counts is recommended prior to administering each dose of carboplatin in order to get a rough idea of toxicity as it will suppress neutrophils (a specific type of white blood cell) at toxic levels.
	www.vetinfo.com /catcancer.html (7652 words)

	Light and Electron Microscopic Study of Changes in the Organization of the Cortical Actin Cytoskeleton During ...
		Light and Electron Microscopic Study of Changes in the Organization of the Cortical Actin Cytoskeleton During Chromaffin Cell Secretion -- Tchakarov et al.
		Light and Electron Microscopic Study of Changes in the Organization of the Cortical Actin Cytoskeleton During Chromaffin Cell Secretion
		Chromaffin cells cultured for 2 days were incubated in the absence
	www.jhc.org /cgi/content/abstract/46/2/193 (419 words)

	Prof. Dr. Erwin Neher
		DINKELACKER, V., VOETS, T., NEHER, E. The readily releasable pool of vesicles in chromaffin cells is replenished in a temperature-dependent manner and transiently overfills at 37°C. Neurosci.
		Rapid exocytosis in single chromaffin cells recorded from mouse adrenal slices.
		PLATTNER, H., ARTALEJO, A.R. and NEHER, E. Ultrastructural organization of bovine chromaffin cell cortex - analysis by cryofixation and morphometry of aspects pertinent to exocytosis.
	www.mpibpc.gwdg.de /abteilungen/140/erwin_neher (1407 words)

	WCP: Subarachnoid Chromaffin Cell Allograft is Effective Analgesic in Patients with Terminal Cancer Pain (Site not responding. Last check: 2007-10-29)
		Title: WCP: Subarachnoid Chromaffin Cell Allograft is Effective Analgesic in Patients with Terminal Cancer Pain
		SAN DIEGO, CA -- August 20, 2002 -- Subarachnoid chromaffin cell allograft is a safe and effective analgesic in patients with terminal cancer pain, according to a small study presented August 18
		Four patients received active treatment with 2 mL of a suspension of chromaffin cells, which had been cultured
	www.docguide.com /dg.nsf/PrintPrint/9D4C1678B70B7D7685256C1B00470D3D (385 words)

	Ultrastructural Organization of Bovine Chromaffin Cell Cortex---Analysis by Cryofixation and Morphometry of Aspects ...
		Ultrastructural Organization of Bovine Chromaffin Cell Cortex---Analysis by Cryofixation and Morphometry of Aspects Pertinent to Exocytosis -- Plattner et al.
		We have analyzed ultrathin sections from isolated bovine chromaffin cells grown on plastic support, after fast freezing, by
		the center of DVs to the cell membrane (CM) is analyzed, DV density
	www.jcb.org /cgi/content/abstract/139/7/1709 (1145 words)

	New Insights into the Genetics of Familial Chromaffin Cell Tumors -- KOCH et al. 970 (1): 11 -- Annals of the New York ...
		New Insights into the Genetics of Familial Chromaffin Cell Tumors -- KOCH et al.
		of the molecular pathogenesis of familial chromaffin cell tumors
		underlying the pathogenesis of chromaffin cell tumors remain
	www.annalsnyas.org /cgi/content/abstract/970/1/11 (457 words)

	Schweizer Lab Publications
		Schweizer and M. Burger (1986) Digitonin-permeabilized cells are exocytosis competent.
		Thoenen, R. Bookman and M. Burger (1989) Inhibition of exocytosis by intracellularly applied antibodies against a chromaffin granule binding protein.
		Schweizer (1988) Fast and slow phases in chromaffin cell exocytosis depend on Ca entry and Ca buffering.
	www.neurobio.ucla.edu /~felixs/publications.htm (817 words)

	Deletion of tyrosine hydroxylase gene reveals functional interdependence of adrenocortical and chromaffin cell system ...
		Deletion of tyrosine hydroxylase gene reveals functional interdependence of adrenocortical and chromaffin cell system in vivo
		Departments of Neuroscience and Anatomy and Cell Biology, Tufts University School of Medicine, Boston, MA 02111
		Catecholamines are produced in the medulla of the adrenal gland and may participate in the intraglandular regulation of its
	www.pnas.org /cgi/content/abstract/97/26/14742 (548 words)

	News - Subarachnoid Chromaffin Cell Allograft is Effective Analgesic in Patients with Terminal Cancer Pain: Presented ...
		News - Subarachnoid Chromaffin Cell Allograft is Effective Analgesic in Patients with Terminal Cancer Pain: Presented at WCP
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		Subarachnoid Chromaffin Cell Allograft is Effective Analgesic in Patients with Terminal Cancer Pain: Presented at WCP
	www.docguide.com /news/content.nsf/news/8525697700573E1885256C1B00470D3D (372 words)

	ANNALS ONLINE -- Collected Resources : Chromaffin Cell (Site not responding. Last check: 2007-10-29)
		ANNALS ONLINE -- Collected Resources : Chromaffin Cell
		Part I. Molecular Biology of the Chromaffin Cell
		Neuroendocrine Cell Type-Specific and Inducible Expression of Chromogranin/Secretogranin Genes: Crucial Promoter Motifs
	www.annalsnyas.org /cgi/collection/chromaffin (226 words)

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