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Transcriptome analysis of human autosomal trisomy |
 | | However, each trisomy shows considerable variability in the severity and pattern of associated malformations, which cannot be accurately predicted by the karyotype. |
| | In t21 chromosome 21 showed the largest increase and was the only one to differ significantly from the mean for all other chromosomes. |
| | In t13 there was much more variability in the transcriptosome ratios with several chromosomes showing significant misregulation, however, chromosome 13 showed the largest upregulation and was the only transcriptosome where the standard error did not overlap with any other chromosome. |
| journals.aol.com /patoco2/TrisomyDisorders/entries/2006/03/27/transcriptome-analysis-of-human-autosomal-trisomy/1013 (1126 words) |
